Engineering fibrin matrices: The engagement of polymerization pockets through fibrin knob technology for the delivery and retention of therapeutic proteins

Biomaterials

Volumn 31, Issue 7, 2010, Pages 1944-1954

  Soon, Allyson S C ^a   Stabenfeldt, Sarah E ^a   Brown, Wendy E ^a   Barker, Thomas H ^a  

^a Wallace H Coulter Department of Biomedical Engineering   (United States)

Author keywords

Affinity; Controlled drug release; Fibrin; Fibrinogen; Molecular biology; Recombinant protein

Indexed keywords

AFFINITY; BINDING AFFINITIES; CATALYZED CONVERSION; CELL INFILTRATION; CONFOCAL IMAGING; CONTROLLED DRUG RELEASE; EQUILIBRIUM DISSOCIATION CONSTANT; EXTRACELLULAR MATRICES; FIBRIN MATRIX; FIBRIN NETWORK; FIBRONECTIN FRAGMENTS; INTEGRINS; MATRIX; MODEL PROTEINS; MOLAR EXCESS; N-TERMINALS; PERFUSION CONDITIONS; PLATFORM SYSTEMS; PROTEIN DELIVERY; PROTEIN FACTORS; PROTEIN FUSION; RECOMBINANT PROTEIN; RELEASE PROFILES; SURGICAL SEALANTS; THERAPEUTIC PROTEIN;

BINDING ENERGY; BIOCHEMISTRY; DISSOCIATION; EQUILIBRIUM CONSTANTS; FUNCTIONAL POLYMERS; KNOBS; MOLECULAR BIOLOGY; MOLECULAR STRUCTURE; SURFACE PLASMON RESONANCE;

PROTEINS;

FIBRIN; FIBRONECTIN; RECOMBINANT PROTEIN;

ARTICLE; BINDING AFFINITY; CONTROLLED DRUG RELEASE; DISSOCIATION CONSTANT; DRUG DELIVERY SYSTEM; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; MOLECULAR BIOLOGY; MOLECULAR STABILITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN INTERACTION; PROTEIN POLYMERIZATION;

BATROXOBIN; BIOPOLYMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FACTOR XIIIA; FIBRIN; FIBRINOGEN; HUMANS; OLIGOPEPTIDES; PERFUSION; PROTEIN BINDING; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; SURFACE PLASMON RESONANCE; THROMBIN;

EID: 73249130099     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.10.060     Document Type: Article

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