메뉴 건너뛰기




Volumn 40, Issue 4, 2012, Pages 204-210

Severe obesity: Evidence for a deranged metabolic program in skeletal muscle?

Author keywords

bariatric surgery; Class III obesity; exercise training; fat oxidation; insulin action; mitochondria; obesity

Indexed keywords

ANIMAL; ARTICLE; FAT INTAKE; HUMAN; LIPID METABOLISM; METABOLISM; MORBID OBESITY; PATHOLOGY; SKELETAL MUSCLE; TISSUE CULTURE TECHNIQUE; WEIGHT REDUCTION;

EID: 84866943696     PISSN: 00916331     EISSN: None     Source Type: Journal    
DOI: 10.1097/JES.0b013e31825d53fc     Document Type: Article
Times cited : (42)

References (35)
  • 1
    • 0029066976 scopus 로고
    • Hypoxia stimulates glucose transport in insulin-resistant human skeletal muscle
    • Azevedo JL Jr, Carey JO, Pories WJ, Morris PG, Dohm GL. Hypoxia stimulates glucose transport in insulin-resistant human skeletal muscle. Diabetes. 1995; 44:695-8.
    • (1995) Diabetes. , vol.44 , pp. 695-8
    • Azevedo Jr., J.L.1    Carey, J.O.2    Pories, W.J.3    Morris, P.G.4    Dohm, G.L.5
  • 2
    • 77954905826 scopus 로고    scopus 로고
    • Lipid partitioning, incomplete fatty acid oxidation, and insulin signal transduction in primary human muscle cells: Effects of severe obesity, fatty acid incubation, and fatty acid translocase/CD36 overexpression
    • Bell JA, Reed MA, Consitt LA, et al. Lipid partitioning, incomplete fatty acid oxidation, and insulin signal transduction in primary human muscle cells: Effects of severe obesity, fatty acid incubation, and fatty acid translocase/CD36 overexpression. J. Clin. Endocrinol. Metab. 2010; 95: 3400-10.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 3400-10
    • Bell, J.A.1    Reed, M.A.2    Consitt, L.A.3
  • 4
    • 57349109343 scopus 로고    scopus 로고
    • Mechanism for improved insulin sensitivity after gastric bypass surgery
    • Bikman BT, Zheng D, Pories WJ, et al. Mechanism for improved insulin sensitivity after gastric bypass surgery. J. Clin. Endocrinol. Metab. 2008; 93:4656-63.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 4656-63
    • Bikman, B.T.1    Zheng, D.2    Pories, W.J.3
  • 6
    • 79952295016 scopus 로고    scopus 로고
    • A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals
    • Boyle KE, Canham JP, Consitt LA, et al. A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals. J. Clin. Endocrinol. Metab. 2011; 96:775-81.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 775-81
    • Boyle, K.E.1    Canham, J.P.2    Consitt, L.A.3
  • 8
    • 0037381535 scopus 로고    scopus 로고
    • Defective signaling through Akt- 2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: Potential role in insulin resistance
    • Brozinick JT Jr, Roberts BR, Dohm GL. Defective signaling through Akt- 2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: Potential role in insulin resistance. Diabetes. 2003; 52:935-41.
    • (2003) Diabetes. , vol.52 , pp. 935-41
    • Brozinick Jr., J.T.1    Roberts, B.R.2    Dohm, G.L.3
  • 9
    • 0029063669 scopus 로고
    • Okadaic acid, vanadate, and phenylarsine oxide stimulate 2-deoxyglucose transport in insulin-resistant human skeletal muscle
    • Carey JO, Azevedo JL Jr, Morris PG, Pories WJ, Dohm GL. Okadaic acid, vanadate, and phenylarsine oxide stimulate 2-deoxyglucose transport in insulin-resistant human skeletal muscle. Diabetes. 1995; 44:682-8.
    • (1995) Diabetes. , vol.44 , pp. 682-8
    • Carey, J.O.1    Azevedo Jr., J.L.2    Morris, P.G.3    Pories, W.J.4    Dohm, G.L.5
  • 10
    • 0023222361 scopus 로고
    • Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes
    • Caro JF, Sinha MK, Raju SM, et al. Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes. J. Clin. Invest. 1987; 79:1330-7.
    • (1987) J. Clin. Invest. , vol.79 , pp. 1330-7
    • Caro, J.F.1    Sinha, M.K.2    Raju, S.M.3
  • 11
    • 77953189610 scopus 로고    scopus 로고
    • Peroxisome proliferatorYactivated receptorYgamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals
    • Consitt LA, Bell JA, Koves TR, et al. Peroxisome proliferatorYactivated receptorYgamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals. Diabetes. 2010; 59:1407-15.
    • (2010) Diabetes. , vol.59 , pp. 1407-15
    • Consitt, L.A.1    Bell, J.A.2    Koves, T.R.3
  • 13
    • 0025144452 scopus 로고
    • IGF-IYstimulated glucose transport in human skeletal muscle and IGF-I resistance in obesity and NIDDM
    • Dohm GL, Elton CW, Raju MS, et al. IGF-IYstimulated glucose transport in human skeletal muscle and IGF-I resistance in obesity and NIDDM. Diabetes. 1990; 39:1028-32.
    • (1990) Diabetes. , vol.39 , pp. 1028-32
    • Dohm, G.L.1    Elton, C.W.2    Raju, M.S.3
  • 15
    • 0027392973 scopus 로고
    • Contractile activity restores insulin responsiveness in skeletal muscle of obese Zucker rats
    • Dolan PL, Tapscott EB, Dorton PJ, Dohm GL. Contractile activity restores insulin responsiveness in skeletal muscle of obese Zucker rats. Biochem. J. 1993; 289(pt 2):423-6.
    • (1993) Biochem. J. , vol.289 , Issue.PART 2 , pp. 423-6
    • Dolan, P.L.1    Tapscott, E.B.2    Dorton, P.J.3    Dohm, G.L.4
  • 16
    • 0028224164 scopus 로고
    • Effect of moderate obesity on glucose transport in human muscle.Horm
    • Elton CW, Tapscott EB, Pories WJ, Dohm GL. Effect of moderate obesity on glucose transport in human muscle.Horm. Metab. Res. 1994; 26:181-3.
    • (1994) Metab. Res. , vol.26 , pp. 181-3
    • Elton, C.W.1    Tapscott, E.B.2    Pories, W.J.3    Dohm, G.L.4
  • 17
    • 0027939941 scopus 로고
    • Glucose metabolism in incubated human muscle: Effect of obesity and noninsulin- dependent diabetes mellitus
    • Friedman JE, Caro JF, Pories WJ, Azevedo JL Jr, Dohm GL. Glucose metabolism in incubated human muscle: Effect of obesity and noninsulin- dependent diabetes mellitus. Metabolism. 1994; 43:1047-54.
    • (1994) Metabolism. , vol.43 , pp. 1047-54
    • Friedman, J.E.1    Caro, J.F.2    Pories, W.J.3    Azevedo Jr., J.L.4    Dohm, G.L.5
  • 19
    • 0028903232 scopus 로고
    • Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects
    • Goodyear LJ, Giorgino F, Sherman LA, Carey J, Smith RJ, Dohm GL. Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. J. Clin. Invest. 1995; 95:2195-204.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2195-204
    • Goodyear, L.J.1    Giorgino, F.2    Sherman, L.A.3    Carey, J.4    Smith, R.J.5    Dohm, G.L.6
  • 21
    • 0035112464 scopus 로고    scopus 로고
    • Substrate utilization during exercise in formerly morbidly obese women
    • Guesbeck NR, Hickey MS, MacDonald KG, et al. Substrate utilization during exercise in formerly morbidly obese women. J. Appl. Physiol. 2001; 90:1007-12.
    • (2001) J. Appl. Physiol. , vol.90 , pp. 1007-12
    • Guesbeck, N.R.1    Hickey, M.S.2    MacDonald, K.G.3
  • 22
    • 0029157866 scopus 로고
    • Skeletal muscle fiber composition is related to adiposity and in vitro glucose transport rate in humans
    • Hickey MS, Carey JO, Azevedo JL, et al. Skeletal muscle fiber composition is related to adiposity and in vitro glucose transport rate in humans. Am. J. Physiol. 1995; 268:E453-7.
    • (1995) Am. J. Physiol. , vol.268
    • Hickey, M.S.1    Carey, J.O.2    Azevedo, J.L.3
  • 23
    • 0001786537 scopus 로고    scopus 로고
    • Effects of 7 days of exercise training on insulin action in morbidly obese men
    • Hickey MS, Gavingan KE, McCammon MR, et al. Effects of 7 days of exercise training on insulin action in morbidly obese men. Clin. Exerc. Physiol. 1999; 1:24-8.
    • (1999) Clin. Exerc. Physiol. , vol.1 , pp. 24-8
    • Hickey, M.S.1    Gavingan, K.E.2    McCammon, M.R.3
  • 24
    • 17844391820 scopus 로고    scopus 로고
    • Proteome analysis of skeletal muscle from obese and morbidly obese women
    • Hittel DS, Hathout Y, Hoffman EP, Houmard JA. Proteome analysis of skeletal muscle from obese and morbidly obese women. Diabetes. 2005; 54:1283-8.
    • (2005) Diabetes. , vol.54 , pp. 1283-8
    • Hittel, D.S.1    Hathout, Y.2    Hoffman, E.P.3    Houmard, J.A.4
  • 25
    • 0036789205 scopus 로고    scopus 로고
    • Effect of weight loss on insulin sensitivity and intramuscular long-chain fatty acyl-CoAs in morbidly obese subjects
    • Houmard JA, Tanner CJ, Yu C, et al. Effect of weight loss on insulin sensitivity and intramuscular long-chain fatty acyl-CoAs in morbidly obese subjects. Diabetes. 2002; 51:2959-63.
    • (2002) Diabetes. , vol.51 , pp. 2959-63
    • Houmard, J.A.1    Tanner, C.J.2    Yu, C.3
  • 26
    • 33644821916 scopus 로고    scopus 로고
    • Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans
    • Hulver MW, Berggren JR, Carper MJ, et al. Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab. 2005; 2:251-61.
    • (2005) Cell Metab. , vol.2 , pp. 251-61
    • Hulver, M.W.1    Berggren, J.R.2    Carper, M.J.3
  • 28
    • 0033861608 scopus 로고    scopus 로고
    • Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity
    • Itani SI, Zhou Q, Pories WJ, MacDonald KG, Dohm GL. Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity. Diabetes. 2000; 49:1353-8.
    • (2000) Diabetes. , vol.49 , pp. 1353-8
    • Itani, S.I.1    Zhou, Q.2    Pories, W.J.3    MacDonald, K.G.4    Dohm, G.L.5
  • 30
    • 33846917548 scopus 로고    scopus 로고
    • GRB14, GPD1, and GDF8 as potential network collaborators in weight lossY induced improvements in insulin action in human skeletal muscle
    • Park JJ, Berggren JR, Hulver MW, Houmard JA, Hoffman EP. GRB14, GPD1, and GDF8 as potential network collaborators in weight lossY induced improvements in insulin action in human skeletal muscle. Physiol. Genomics. 2006; 27:114-21.
    • (2006) Physiol. Genomics. , vol.27 , pp. 114-21
    • Park, J.J.1    Berggren, J.R.2    Hulver, M.W.3    Houmard, J.A.4    Hoffman, E.P.5
  • 31
    • 1542300118 scopus 로고    scopus 로고
    • Muscle insulin receptor concentrations in obese patients post bariatric surgery: Relationship to hyperinsulinemia
    • Pender C, Goldfine ID, Tanner CJ, et al. Muscle insulin receptor concentrations in obese patients post bariatric surgery: Relationship to hyperinsulinemia. Int. J. Obes. Relat. Metab. Disord. 2004; 28:363-9.
    • (2004) Int. J. Obes. Relat. Metab. Disord. , vol.28 , pp. 363-9
    • Pender, C.1    Goldfine, I.D.2    Tanner, C.J.3
  • 32
    • 79961238549 scopus 로고    scopus 로고
    • Roux-en-Y gastric bypass corrects hyperinsulinemia implications for the remission of type 2 diabetes
    • Reed MA, Pories WJ, Chapman W, et al. Roux-en-Y gastric bypass corrects hyperinsulinemia implications for the remission of type 2 diabetes. J. Clin. Endocrinol. Metab. 2011; 96:2525-31.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 2525-31
    • Reed, M.A.1    Pories, W.J.2    Chapman, W.3
  • 35
    • 0033056557 scopus 로고    scopus 로고
    • Dephosphorylation increases insulinstimulated receptor kinase activity in skeletal muscle of obese Zucker rats
    • Zhou Q, Dolan PL, Dohm GL. Dephosphorylation increases insulinstimulated receptor kinase activity in skeletal muscle of obese Zucker rats. Mol. Cell. Biochem. 1999; 194:209-16.
    • (1999) Mol. Cell. Biochem. , vol.194 , pp. 209-16
    • Zhou, Q.1    Dolan, P.L.2    Dohm, G.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.