Prokaryotic substrate-binding proteins as targets for antimicrobial therapies

Current Drug Targets

Volumn 13, Issue 11, 2012, Pages 1400-1410

  Couñago, Rafael M ^a   McDevitt, Christopher A ^b   Ween, Miranda P ^b   Kobe, Bostjan ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

ABC transporter; Antimicrobials; ATP binding cassette; Bacterial pathogens; Cluster A 1 SBP; Drug design; Metal binding; Substrate binding protein (SBP)

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; ANTIINFECTIVE AGENT; BINDING PROTEIN; COPPER; IRON; LIPID; MANGANESE; METAL; PNEUMOCOCCUS VACCINE; PROTEIN ADCAII; PROTEIN LBP; PROTEIN MNTC; PROTEIN MTSA; PROTEIN PSAA; PROTEIN TROA; PROTEIN ZNUA; SUBSTRATE BINDING PROTEIN; UNCLASSIFIED DRUG; ZINC;

BACTERIAL CELL; BACTERIAL COLONIZATION; BACTERIAL VIRULENCE; CYTOPLASM; CYTOSOL; DRUG TARGETING; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HYDROLYSIS; NONHUMAN; PNEUMOCOCCAL INFECTION; PROKARYOTE; PROTEIN CONFORMATION; PROTEIN FAMILY; REVIEW; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM;

ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL PROTEINS; MODELS, MOLECULAR; PROKARYOTIC CELLS; SUBSTRATE SPECIFICITY; VIRULENCE;

EID: 84866930055     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: 10.2174/138945012803530170     Document Type: Review

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