-
1
-
-
38849098442
-
Cancer proliferation gene discovery through functional genomics
-
Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, et al. (2008) Cancer proliferation gene discovery through functional genomics. Science 319: 620-624.
-
(2008)
Science
, vol.319
, pp. 620-624
-
-
Schlabach, M.R.1
Luo, J.2
Solimini, N.L.3
Hu, G.4
Xu, Q.5
-
2
-
-
38849192515
-
Profiling essential genes in human mammary cells by multiplex RNAi screening
-
Silva JM, Marran K, Parker JS, Silva J, Golding M, et al. (2008) Profiling essential genes in human mammary cells by multiplex RNAi screening. Science 319: 617-620.
-
(2008)
Science
, vol.319
, pp. 617-620
-
-
Silva, J.M.1
Marran, K.2
Parker, J.S.3
Silva, J.4
Golding, M.5
-
3
-
-
78149489180
-
RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells
-
Bauer JA, Ye F, Marshall CB, Lehmann BD, Pendleton CS, et al. (2010) RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells. Breast Cancer Res 12: R41.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Bauer, J.A.1
Ye, F.2
Marshall, C.B.3
Lehmann, B.D.4
Pendleton, C.S.5
-
4
-
-
35148885729
-
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
-
Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, et al. (2007) A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer. Cancer Cell 12: 395-402.
-
(2007)
Cancer Cell
, vol.12
, pp. 395-402
-
-
Berns, K.1
Horlings, H.M.2
Hennessy, B.T.3
Madiredjo, M.4
Hijmans, E.M.5
-
5
-
-
58249090328
-
Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitization
-
Iorns E, Lord CJ, Ashworth A, (2009) Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitization. Biochem J 417: 361-370.
-
(2009)
Biochem J
, vol.417
, pp. 361-370
-
-
Iorns, E.1
Lord, C.J.2
Ashworth, A.3
-
6
-
-
33644623149
-
An overview of chemosensitivity testing
-
Blumenthal RD, (2005) An overview of chemosensitivity testing. Methods Mol Med 110: 3-18.
-
(2005)
Methods Mol Med
, vol.110
, pp. 3-18
-
-
Blumenthal, R.D.1
-
7
-
-
0001283359
-
In Vitro Cell Transformation with Chemical Carcinogens
-
Berwald Y, Sachs L, (1963) In Vitro Cell Transformation with Chemical Carcinogens. Nature 200: 1182-1184.
-
(1963)
Nature
, vol.200
, pp. 1182-1184
-
-
Berwald, Y.1
Sachs, L.2
-
8
-
-
84869092533
-
The Cancer BioChip System: A functional genomic assay for anchorage-independent three-dimensional breast cancer cell growth
-
Abbud-Antaki RA, Marhefka JN, DeLuca AL, Zuromski MP, (2012) The Cancer BioChip System: A functional genomic assay for anchorage-independent three-dimensional breast cancer cell growth. Horm Cancer.
-
(2012)
Horm Cancer
-
-
Abbud-Antaki, R.A.1
Marhefka, J.N.2
DeLuca, A.L.3
Zuromski, M.P.4
-
9
-
-
39749106670
-
Identifying breast cancer druggable oncogenic alterations: lessons learned and future targeted options
-
Ocana A, Pandiella A, (2008) Identifying breast cancer druggable oncogenic alterations: lessons learned and future targeted options. Clin Cancer Res 14: 961-970.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 961-970
-
-
Ocana, A.1
Pandiella, A.2
-
10
-
-
0032537396
-
Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group
-
Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group. Lancet 351: 1451-1467.
-
Lancet
, vol.351
, pp. 1451-1467
-
-
-
11
-
-
84866874180
-
Role of HER2-Targeted Agents in Adjuvant Treatment for Breast Cancer
-
Mukohara T, (2011) Role of HER2-Targeted Agents in Adjuvant Treatment for Breast Cancer. Chemother Res Pract 2011: 730360.
-
(2011)
Chemother Res Pract
, vol.2011
, pp. 730360
-
-
Mukohara, T.1
-
12
-
-
78651101402
-
Phase I/II study of sorafenib with anastrozole in patients with hormone receptor positive aromatase inhibitor resistant metastatic breast cancer
-
Isaacs C, Herbolsheimer P, Liu MC, Wilkinson M, Ottaviano Y, et al. (2011) Phase I/II study of sorafenib with anastrozole in patients with hormone receptor positive aromatase inhibitor resistant metastatic breast cancer. Breast Cancer Res Treat 125: 137-143.
-
(2011)
Breast Cancer Res Treat
, vol.125
, pp. 137-143
-
-
Isaacs, C.1
Herbolsheimer, P.2
Liu, M.C.3
Wilkinson, M.4
Ottaviano, Y.5
-
13
-
-
73349122284
-
Relationship between Topoisomerase 2A RNA Expression and Recurrence after Adjuvant Chemotherapy for Breast Cancer
-
Sparano JA, Goldstein LJ, Childs BH, Shak S, Brassard D, et al. (2009) Relationship between Topoisomerase 2A RNA Expression and Recurrence after Adjuvant Chemotherapy for Breast Cancer. Clin Cancer Res 15: 7693-7700.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7693-7700
-
-
Sparano, J.A.1
Goldstein, L.J.2
Childs, B.H.3
Shak, S.4
Brassard, D.5
-
15
-
-
79956340194
-
Targeting IGF-1R: at a crossroad
-
discussion 551
-
Lee AV, Yee D, (2011) Targeting IGF-1R: at a crossroad. Oncology (Williston Park) 25: 535-536; discussion 551.
-
(2011)
Oncology (Williston Park)
, vol.25
, pp. 535-536
-
-
Lee, A.V.1
Yee, D.2
-
16
-
-
77954690732
-
Advances in targeting SRC in the treatment of breast cancer and other solid malignancies
-
Mayer EL, Krop IE, (2010) Advances in targeting SRC in the treatment of breast cancer and other solid malignancies. Clin Cancer Res 16: 3526-3532.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3526-3532
-
-
Mayer, E.L.1
Krop, I.E.2
-
17
-
-
79960985354
-
HSP90 inhibition is effective in breast cancer: a phase II trial of tanespimycin (17-AAG) plus trastuzumab in patients with HER2-positive metastatic breast cancer progressing on trastuzumab
-
Modi S, Stopeck A, Linden H, Solit D, Chandarlapaty S, et al. (2011) HSP90 inhibition is effective in breast cancer: a phase II trial of tanespimycin (17-AAG) plus trastuzumab in patients with HER2-positive metastatic breast cancer progressing on trastuzumab. Clin Cancer Res 17: 5132-5139.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5132-5139
-
-
Modi, S.1
Stopeck, A.2
Linden, H.3
Solit, D.4
Chandarlapaty, S.5
-
18
-
-
70349682188
-
Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker
-
Munster PN, Marchion D, Thomas S, Egorin M, Minton S, et al. (2009) Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker. Br J Cancer 101: 1044-1050.
-
(2009)
Br J Cancer
, vol.101
, pp. 1044-1050
-
-
Munster, P.N.1
Marchion, D.2
Thomas, S.3
Egorin, M.4
Minton, S.5
-
19
-
-
84869092533
-
The Cancer BioChip System: A Functional Genomic Assay for Anchorage-Independent Three-Dimensional Breast Cancer Cell Growth
-
Abbud-Antaki RA, Marhefka JN, Deluca AL, Zuromskis MP, (2012) The Cancer BioChip System: A Functional Genomic Assay for Anchorage-Independent Three-Dimensional Breast Cancer Cell Growth. Horm Cancer.
-
(2012)
Horm Cancer
-
-
Abbud-Antaki, R.A.1
Marhefka, J.N.2
Deluca, A.L.3
Zuromskis, M.P.4
-
20
-
-
0033003760
-
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
-
Zhang JH, Chung TD, Oldenburg KR, (1999) A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J Biomol Screen 4: 67-73.
-
(1999)
J Biomol Screen
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
21
-
-
80053465657
-
Functional viability profiles of breast cancer
-
Brough R, Frankum JR, Sims D, Mackay A, Mendes-Pereira AM, et al. (2011) Functional viability profiles of breast cancer. Cancer Discov 1: 260-273.
-
(2011)
Cancer Discov
, vol.1
, pp. 260-273
-
-
Brough, R.1
Frankum, J.R.2
Sims, D.3
Mackay, A.4
Mendes-Pereira, A.M.5
-
22
-
-
33751166800
-
Stable knockdown of estrogen receptor alpha by vector-based RNA interference suppresses proliferation and enhances apoptosis in breast cancer cells
-
Fu HJ, Jia LT, Bao W, Zhao J, Meng YL, et al. (2006) Stable knockdown of estrogen receptor alpha by vector-based RNA interference suppresses proliferation and enhances apoptosis in breast cancer cells. Cancer Biol Ther 5: 842-847.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 842-847
-
-
Fu, H.J.1
Jia, L.T.2
Bao, W.3
Zhao, J.4
Meng, Y.L.5
-
23
-
-
55749110592
-
SiRNA inhibition of ER-alpha expression reduces KGF-induced proliferation of breast cancer cells
-
Zang XP, Pento JT, (2008) SiRNA inhibition of ER-alpha expression reduces KGF-induced proliferation of breast cancer cells. Anticancer Res 28: 2733-2735.
-
(2008)
Anticancer Res
, vol.28
, pp. 2733-2735
-
-
Zang, X.P.1
Pento, J.T.2
-
24
-
-
11144348206
-
Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells
-
Faltus T, Yuan J, Zimmer B, Kramer A, Loibl S, et al. (2004) Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells. Neoplasia 6: 786-795.
-
(2004)
Neoplasia
, vol.6
, pp. 786-795
-
-
Faltus, T.1
Yuan, J.2
Zimmer, B.3
Kramer, A.4
Loibl, S.5
-
25
-
-
65249161106
-
Integrated functional, gene expression and genomic analysis for the identification of cancer targets
-
Iorns E, Lord CJ, Grigoriadis A, McDonald S, Fenwick K, et al. (2009) Integrated functional, gene expression and genomic analysis for the identification of cancer targets. PLoS One 4: e5120.
-
(2009)
PLoS One
, vol.4
-
-
Iorns, E.1
Lord, C.J.2
Grigoriadis, A.3
McDonald, S.4
Fenwick, K.5
-
26
-
-
77749299074
-
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression
-
Nencioni A, Cea M, Garuti A, Passalacqua M, Raffaghello L, et al. (2010) Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression. PLoS One 5: e9024.
-
(2010)
PLoS One
, vol.5
-
-
Nencioni, A.1
Cea, M.2
Garuti, A.3
Passalacqua, M.4
Raffaghello, L.5
-
27
-
-
34247468876
-
Regulation of the actin cytoskeleton in cancer cell migration and invasion
-
Yamaguchi H, Condeelis J, (2007) Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta 1773: 642-652.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 642-652
-
-
Yamaguchi, H.1
Condeelis, J.2
-
28
-
-
51049121572
-
Identification of genes that regulate epithelial cell migration using an siRNA screening approach
-
Simpson KJ, Selfors LM, Bui J, Reynolds A, Leake D, et al. (2008) Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nat Cell Biol 10: 1027-1038.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1027-1038
-
-
Simpson, K.J.1
Selfors, L.M.2
Bui, J.3
Reynolds, A.4
Leake, D.5
-
29
-
-
35948930595
-
Abelson interactor protein-1 positively regulates breast cancer cell proliferation, migration, and invasion
-
Wang C, Navab R, Iakovlev V, Leng Y, Zhang J, et al. (2007) Abelson interactor protein-1 positively regulates breast cancer cell proliferation, migration, and invasion. Mol Cancer Res 5: 1031-1039.
-
(2007)
Mol Cancer Res
, vol.5
, pp. 1031-1039
-
-
Wang, C.1
Navab, R.2
Iakovlev, V.3
Leng, Y.4
Zhang, J.5
-
30
-
-
0026549659
-
Changes in the cytoskeleton pattern of tumor cells by cisplatin in vitro
-
Kopf-Maier P, Muhlhausen SK, (1992) Changes in the cytoskeleton pattern of tumor cells by cisplatin in vitro. Chem Biol Interact 82: 295-316.
-
(1992)
Chem Biol Interact
, vol.82
, pp. 295-316
-
-
Kopf-Maier, P.1
Muhlhausen, S.K.2
-
31
-
-
0034960408
-
Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine
-
Ngan VK, Bellman K, Hill BT, Wilson L, Jordan MA, (2001) Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine. Mol Pharmacol 60: 225-232.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 225-232
-
-
Ngan, V.K.1
Bellman, K.2
Hill, B.T.3
Wilson, L.4
Jordan, M.A.5
-
32
-
-
79953035125
-
Actin disruption agents induce phosphorylation of histone H2AX in human breast adenocarcinoma MCF-7 cells
-
Shin IJ, Ahn YT, Kim Y, Kim JM, An WG, (2011) Actin disruption agents induce phosphorylation of histone H2AX in human breast adenocarcinoma MCF-7 cells. Oncol Rep 25: 1313-1319.
-
(2011)
Oncol Rep
, vol.25
, pp. 1313-1319
-
-
Shin, I.J.1
Ahn, Y.T.2
Kim, Y.3
Kim, J.M.4
An, W.G.5
-
33
-
-
79951862799
-
The role of the cytoskeleton in cellular force generation in 2D and 3D environments
-
Kraning-Rush CM, Carey SP, Califano JP, Smith BN, Reinhart-King CA, (2011) The role of the cytoskeleton in cellular force generation in 2D and 3D environments. Phys Biol 8: 015009.
-
(2011)
Phys Biol
, vol.8
, pp. 015009
-
-
Kraning-Rush, C.M.1
Carey, S.P.2
Califano, J.P.3
Smith, B.N.4
Reinhart-King, C.A.5
-
34
-
-
78149465975
-
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity
-
Chia NY, Chan YS, Feng B, Lu X, Orlov YL, et al. (2010) A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature 468: 316-320.
-
(2010)
Nature
, vol.468
, pp. 316-320
-
-
Chia, N.Y.1
Chan, Y.S.2
Feng, B.3
Lu, X.4
Orlov, Y.L.5
-
35
-
-
0030970119
-
Emerging roles for cysteine proteases in human biology
-
Chapman HA, Riese RJ, Shi GP, (1997) Emerging roles for cysteine proteases in human biology. Annu Rev Physiol 59: 63-88.
-
(1997)
Annu Rev Physiol
, vol.59
, pp. 63-88
-
-
Chapman, H.A.1
Riese, R.J.2
Shi, G.P.3
-
36
-
-
36949011597
-
Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia
-
Boudreau F, Lussier CR, Mongrain S, Darsigny M, Drouin JL, et al. (2007) Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia. FASEB J 21: 3853-3865.
-
(2007)
FASEB J
, vol.21
, pp. 3853-3865
-
-
Boudreau, F.1
Lussier, C.R.2
Mongrain, S.3
Darsigny, M.4
Drouin, J.L.5
-
37
-
-
33644784910
-
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis
-
Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, et al. (2006) Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev 20: 543-556.
-
(2006)
Genes Dev
, vol.20
, pp. 543-556
-
-
Gocheva, V.1
Zeng, W.2
Ke, D.3
Klimstra, D.4
Reinheckel, T.5
-
38
-
-
34548689404
-
Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation
-
Goulet B, Sansregret L, Leduy L, Bogyo M, Weber E, et al. (2007) Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation. Mol Cancer Res 5: 899-907.
-
(2007)
Mol Cancer Res
, vol.5
, pp. 899-907
-
-
Goulet, B.1
Sansregret, L.2
Leduy, L.3
Bogyo, M.4
Weber, E.5
-
39
-
-
34547640302
-
Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer
-
Bell-McGuinn KM, Garfall AL, Bogyo M, Hanahan D, Joyce JA, (2007) Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer. Cancer Res 67: 7378-7385.
-
(2007)
Cancer Res
, vol.67
, pp. 7378-7385
-
-
Bell-McGuinn, K.M.1
Garfall, A.L.2
Bogyo, M.3
Hanahan, D.4
Joyce, J.A.5
-
40
-
-
58349113405
-
Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism
-
Zheng X, Chu F, Chou PM, Gallati C, Dier U, et al. (2009) Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism. Am J Physiol Cell Physiol 296: C65-74.
-
(2009)
Am J Physiol Cell Physiol
, vol.296
-
-
Zheng, X.1
Chu, F.2
Chou, P.M.3
Gallati, C.4
Dier, U.5
-
41
-
-
0035958050
-
Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions
-
Navab R, Chevet E, Authier F, Di Guglielmo GM, Bergeron JJ, et al. (2001) Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions. J Biol Chem 276: 13644-13649.
-
(2001)
J Biol Chem
, vol.276
, pp. 13644-13649
-
-
Navab, R.1
Chevet, E.2
Authier, F.3
Di Guglielmo, G.M.4
Bergeron, J.J.5
-
42
-
-
0032032628
-
Control of breast tumor cell growth using a targeted cysteine protease inhibitor
-
Xing R, Wu F, Mason RW, (1998) Control of breast tumor cell growth using a targeted cysteine protease inhibitor. Cancer Res 58: 904-909.
-
(1998)
Cancer Res
, vol.58
, pp. 904-909
-
-
Xing, R.1
Wu, F.2
Mason, R.W.3
-
43
-
-
53049094306
-
Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2
-
Fehrenbacher N, Bastholm L, Kirkegaard-Sorensen T, Rafn B, Bottzauw T, et al. (2008) Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2. Cancer Res 68: 6623-6633.
-
(2008)
Cancer Res
, vol.68
, pp. 6623-6633
-
-
Fehrenbacher, N.1
Bastholm, L.2
Kirkegaard-Sorensen, T.3
Rafn, B.4
Bottzauw, T.5
-
44
-
-
77949656494
-
Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis
-
Dennemarker J, Lohmuller T, Mayerle J, Tacke M, Lerch MM, et al. (2010) Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis. Oncogene 29: 1611-1621.
-
(2010)
Oncogene
, vol.29
, pp. 1611-1621
-
-
Dennemarker, J.1
Lohmuller, T.2
Mayerle, J.3
Tacke, M.4
Lerch, M.M.5
-
45
-
-
33746342801
-
Role of c-Src in human MCF7 breast cancer cell tumorigenesis
-
Gonzalez L, Agullo-Ortuno MT, Garcia-Martinez JM, Calcabrini A, Gamallo C, et al. (2006) Role of c-Src in human MCF7 breast cancer cell tumorigenesis. J Biol Chem 281: 20851-20864.
-
(2006)
J Biol Chem
, vol.281
, pp. 20851-20864
-
-
Gonzalez, L.1
Agullo-Ortuno, M.T.2
Garcia-Martinez, J.M.3
Calcabrini, A.4
Gamallo, C.5
-
46
-
-
0033945861
-
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
-
Rountree MR, Bachman KE, Baylin SB, (2000) DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet 25: 269-277.
-
(2000)
Nat Genet
, vol.25
, pp. 269-277
-
-
Rountree, M.R.1
Bachman, K.E.2
Baylin, S.B.3
-
47
-
-
79251557812
-
Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors
-
Chik F, Szyf M, (2011) Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors. Carcinogenesis 32: 224-232.
-
(2011)
Carcinogenesis
, vol.32
, pp. 224-232
-
-
Chik, F.1
Szyf, M.2
-
48
-
-
79960888804
-
Inferring causal genomic alterations in breast cancer using gene expression data
-
Tran LM, Zhang B, Zhang Z, Zhang C, Xie T, et al. (2011) Inferring causal genomic alterations in breast cancer using gene expression data. BMC Syst Biol 5: 121.
-
(2011)
BMC Syst Biol
, vol.5
, pp. 121
-
-
Tran, L.M.1
Zhang, B.2
Zhang, Z.3
Zhang, C.4
Xie, T.5
-
49
-
-
33748631834
-
Effect of a farnesyl transferase inhibitor (R115777) on ductal carcinoma in situ of the breast in a human xenograft model and on breast and ovarian cancer cell growth in vitro and in vivo
-
Warnberg F, White D, Anderson E, Knox F, Clarke RB, et al. (2006) Effect of a farnesyl transferase inhibitor (R115777) on ductal carcinoma in situ of the breast in a human xenograft model and on breast and ovarian cancer cell growth in vitro and in vivo. Breast Cancer Res 8: R21.
-
(2006)
Breast Cancer Res
, vol.8
-
-
Warnberg, F.1
White, D.2
Anderson, E.3
Knox, F.4
Clarke, R.B.5
-
50
-
-
78751501299
-
Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis
-
Gril B, Palmieri D, Qian Y, Smart D, Ileva L, et al. (2011) Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis. Clin Cancer Res 17: 142-153.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 142-153
-
-
Gril, B.1
Palmieri, D.2
Qian, Y.3
Smart, D.4
Ileva, L.5
-
51
-
-
67649628084
-
Sensitivity of breast cancer cell lines to the novel insulin-like growth factor-1 receptor (IGF-1R) inhibitor NVP-AEW541 is dependent on the level of IRS-1 expression
-
Mukohara T, Shimada H, Ogasawara N, Wanikawa R, Shimomura M, et al. (2009) Sensitivity of breast cancer cell lines to the novel insulin-like growth factor-1 receptor (IGF-1R) inhibitor NVP-AEW541 is dependent on the level of IRS-1 expression. Cancer Lett 282: 14-24.
-
(2009)
Cancer Lett
, vol.282
, pp. 14-24
-
-
Mukohara, T.1
Shimada, H.2
Ogasawara, N.3
Wanikawa, R.4
Shimomura, M.5
-
53
-
-
23644462077
-
Different delivery methods-different expression profiles
-
Fedorov Y, King A, Anderson E, Karpilow J, Ilsley D, et al. (2005) Different delivery methods-different expression profiles. Nat Methods 2: 241.
-
(2005)
Nat Methods
, vol.2
, pp. 241
-
-
Fedorov, Y.1
King, A.2
Anderson, E.3
Karpilow, J.4
Ilsley, D.5
-
54
-
-
0042972933
-
Activation of the interferon system by short-interfering RNAs
-
Sledz CA, Holko M, de Veer MJ, Silverman RH, Williams BR, (2003) Activation of the interferon system by short-interfering RNAs. Nat Cell Biol 5: 834-839.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 834-839
-
-
Sledz, C.A.1
Holko, M.2
de Veer, M.J.3
Silverman, R.H.4
Williams, B.R.5
-
55
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
Bridge AJ, Pebernard S, Ducraux A, Nicoulaz AL, Iggo R, (2003) Induction of an interferon response by RNAi vectors in mammalian cells. Nat Genet 34: 263-264.
-
(2003)
Nat Genet
, vol.34
, pp. 263-264
-
-
Bridge, A.J.1
Pebernard, S.2
Ducraux, A.3
Nicoulaz, A.L.4
Iggo, R.5
-
56
-
-
33646188259
-
3' UTR seed matches, but not overall identity, are associated with RNAi off-targets
-
Birmingham A, Anderson EM, Reynolds A, Ilsley-Tyree D, Leake D, et al. (2006) 3' UTR seed matches, but not overall identity, are associated with RNAi off-targets. Nat Methods 3: 199-204.
-
(2006)
Nat Methods
, vol.3
, pp. 199-204
-
-
Birmingham, A.1
Anderson, E.M.2
Reynolds, A.3
Ilsley-Tyree, D.4
Leake, D.5
-
57
-
-
33745614074
-
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing
-
Jackson AL, Burchard J, Leake D, Reynolds A, Schelter J, et al. (2006) Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing. RNA 12: 1197-1205.
-
(2006)
RNA
, vol.12
, pp. 1197-1205
-
-
Jackson, A.L.1
Burchard, J.2
Leake, D.3
Reynolds, A.4
Schelter, J.5
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