A randomized trial of DHA intake during infancy: School readiness and receptive vocabulary at 2-3.5years of age

Early Human Development

Volumn 88, Issue 11, 2012, Pages 885-891

  Drover, James R ^a,b   Felius, Joost ^b,c   Hoffman, Dennis R ^b,c   Castañeda, Yolanda S ^b   Garfield, Sharon ^b   Wheaton, Dianna H ^b,c   Birch, Eileen E ^b,c  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^b RETINA FOUNDATION OF THE SOUTHWEST   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cognitive development; Docosahexaenoic acid; Infant; School readiness; Vocabulary

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID;

APGAR SCORE; ARTICLE; ARTIFICIAL MILK; CHILD; CHILD DEVELOPMENT; COGNITIVE DEVELOPMENT; COMPREHENSION; CONTROLLED STUDY; EDUCATIONAL STATUS; FATTY ACID ANALYSIS; FEMALE; HUMAN; INFANT; LANGUAGE DEVELOPMENT; LINGUISTICS; MAJOR CLINICAL STUDY; MALE; NUTRIENT CONTENT; PRESCHOOL CHILD; PROBLEM SOLVING; RANDOMIZED CONTROLLED TRIAL; SCHOOL; SELF CONCEPT; VISUAL ACUITY;

CASE-CONTROL STUDIES; CHILD, PRESCHOOL; DOCOSAHEXAENOIC ACIDS; FEMALE; HUMANS; INFANT; INFANT FORMULA; INFANT, NEWBORN; LANGUAGE DEVELOPMENT; MALE; SCHOOLS; VOCABULARY;

EID: 84866873127     PISSN: 03783782     EISSN: 18726232     Source Type: Journal    
DOI: 10.1016/j.earlhumdev.2012.07.007     Document Type: Article

References (49)

1. Dobbing J., Sands J. Quantitative growth and development of human brain. Arch Dis Child 1973, 48:757-767.
2. Anderson J.W., Johnstone B.M., Remley D.T. Breast-feeding and cognitive development: a meta-analysis. Am J Clin Nutr 1999, 70:525-535.
3. Horwood L.J., Darlow B.A., Mogridge N. Breast milk feeding and cognitive ability at 7-8years. Arch Dis Child Fetal Neonatal Ed 2001, 84:F23-F27.
4. Horwood L.J., Fergusson D.M. Breastfeeding and later cognitive and academic outcomes. Pediatrics 1998, 101:E9.
5. Kramer M.S., Aboud F., Mironova E., Vanilovich I., Platt R.W., Matush L., et al. Breastfeeding and child cognitive development: new evidence from a large randomized trial. Arch Gen Psychiatry 2008, 65:578-584.
6. Oddy W.H., Kendall G.E., Blair E., De Klerk N.H., Stanley F.J., Landau L.I., et al. Breast feeding and cognitive development in childhood: a prospective birth cohort study. Paediatr Perinat Epidemiol 2003, 17:81-90.
7. Slykerman R.F., Thompson J.M., Becroft D.M., Robinson E., Pryor J.E., Clark P.M., et al. Breastfeeding and intelligence of preschool children. Acta Paediatr 2005, 94:832-837.
8. Helland I.B., Smith L., Saarem K., Saugstad O.D., Drevon C.A. Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4years of age. Pediatrics 2003, 111:e39-e44.
9. Jensen C.L., Voigt R.G., Prager T.C., Zou Y.L., Fraley J.K., Rozelle J.C., et al. Effects of maternal docosahexaenoic acid intake on visual function and neurodevelopment in breastfed term infants. Am J Clin Nutr 2005, 82:125-132.
10. Judge M.P., Harel O., Lammi-Keefe C.J. Maternal consumption of a docosahexaenoic acid-containing functional food during pregnancy: benefit for infant performance on problem-solving but not on recognition memory tasks at age 9 mo. Am J Clin Nutr 2007, 85:1572-1577.
11. Jensen C.L., Voigt R.G., Llorente A.M., Peters S.U., Prager T.C., Zou Y.L., et al. Effects of early maternal docosahexaenoic acid intake on neuropsychological status and visual acuity at five years of age of breast-fed term infants. J Pediatr 2010, 157:900-905.
12. Birch E.E., Garfield S., Hoffman D.R., Uauy R., Birch D.G. A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants. Dev Med Child Neurol 2000, 42:174-181.
13. Clandinin M.T., Van Aerde J.E., Merkel K.L., Harris C.L., Springer M.A., Hansen J.W., et al. Growth and development of preterm infants fed infant formulas containing docosahexaenoic acid and arachidonic acid. J Pediatr 2005, 146:461-468.
14. Carlson S.E., Werkman S.H., Peeples J.M., Wilson W.M. Long-chain fatty acids and early visual and cognitive development of preterm infants. J Pediatr 1994, 48(Suppl. 2):S27-S30.
15. O'Connor D.L., Hall R., Adamkin D., Auestad N., Castillo M., Connor W.E., et al. Growth and development in preterm infants fed long-chain polyunsaturated fatty acids: a prospective, randomized controlled trial. Pediatrics 2001, 108:359-371.
16. Drover J.R., Hoffman D.R., Castaneda Y.S., Morale S.E., Garfield S., Wheaton D.H., et al. Cognitive function in 18-month-old term infants of the DIAMOND study: a randomized, controlled clinical trial with multiple dietary levels of docosahexaenoic acid. Early Hum Dev 2011, 87:223-230.
17. Agostoni C., Riva E., Trojan S., Bellu R., Giovannini M. Docosahexaenoic acid status and developmental quotient of healthy term infants. Lancet 1995, 346:638.
18. Carlson S.E., Werkman S.H. A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until two months. Lipids 1996, 31:85-90.
19. Werkman S.H., Carlson S.E. A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until nine months. Lipids 1996, 31:91-97.
20. Drover J., Hoffman D.R., Castaneda Y.S., Morale S.E., Birch E.E. Three randomized controlled trials of early long-chain polyunsaturated fatty acid supplementation on means-end problem solving in 9-month-olds. Child Dev 2009, 80:1376-1384.
21. Willatts P., Forsyth J.S., DiModugno M.K., Varma S., Colvin M. Effect of long-chain polyunsaturated fatty acids in infant formula on problem solving at 10months of age. Lancet 1998, 352:688-691.
22. Makrides M., Neumann M.A., Simmer K., Gibson R.A. A critical appraisal of the role of dietary long-chain polyunsaturated fatty acids on neural indices of term infants: a randomized, controlled trial. Pediatrics 2000, 105:32-38.
23. Lucas A., Stafford M., Morley R., Abbott R., Stephenson T., MacFadyen U., et al. Efficacy and safety of long-chain polyunsaturated fatty acid supplementation of infant-formula milk: a randomised trial. Lancet 1999, 354:1948-1954.
24. Bouwstra H., Dijck-Brouwer D.A., Boehm G., Boersma E.R., Muskiet F.A., Hadders-Algra M. Long-chain polyunsaturated fatty acids and neurological developmental outcome at 18months in healthy term infants. Acta Paediatr 2005, 94:26-32.
25. Agostoni C., Trojan S., Bellu R., Riva E., Bruzzese M.G., Giovannini M. Developmental quotient at 24months and fatty acid composition of diet in early infancy: a follow up study. Arch Dis Child 1997, 76:421-424.
26. Scott D.T., Janowsky J.S., Carroll R.E., Taylor J.A., Auestad N., Montalto M.B. Formula supplementation with long-chain polyunsaturated fatty acids: are there developmental benefits?. Pediatrics 1998, 102:E59.
27. Smithers L.G., Collins C.T., Simmonds L.A., Gibson R.A., McPhee A., Makrides M. Feeding preterm infants milk with a higher dose of docosahexaenoic acid than that used in current practice does not influence language or behavior in early childhood: a follow-up study of a randomized controlled trial. Am J Clin Nutr 2010, 91:628-634.
28. Auestad N., Scott D.T., Janowsky J.S., Jacobsen C., Carroll R.E., Montalto M.B., et al. Visual, cognitive, and language assessments at 39months: a follow-up study of children fed formulas containing long-chain polyunsaturated fatty acids to 1year of age. Pediatrics 2003, 112:e177-e183.
29. Auestad N., Halter R., Hall R.T., Blatter M., Bogle M.L., Burks W., et al. Growth anddevelopment in term infants fed long-chain polyunsaturated fatty acids: a double-masked, randomized, parallel, prospective, multivariate study. Pediatrics 2001, 108:372-381.
30. Innis S.M., Gilley J., Werker J. Are human milk long-chain polyunsaturated fatty acids related to visual and neural development in breast-fed term infants?. J Pediatr 2001, 139:532-538.
31. Innis S.M. Perinatal biochemistry and physiology of long-chain polyunsaturated fatty acids. J Pediatr 2003, 143:S1-S8.
32. Lauritzen L., Jorgensen M.H., Olsen S.F., Straarup E.M., Michaelsen K.F. Maternal fish oil supplementation in lactation: effect on developmental outcome in breast-fed infants. Reprod Nutr Dev 2005, 45:535-547.
33. Birch E.E., Carlson S.E., Hoffman D.R., Fitzgerald-Gustafson K.M., Fu V.L., Drover J.R., et al. The DIAMOND (DHA Intake And Measurement Of Neural Development) Study: a double-masked, randomized controlled clinical trial of the maturation of infant visual acuity as a function of the dietary level of docosahexaenoic acid. Am J Clin Nutr 2010, 91:848-859.
34. Brenna J.T., Varamini B., Jensen R.G., Diersen-Schade D.A., Boettcher J.A., Arterburn L.M. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr 2007, 85:1457-1464.
35. Bracken B.A. Bracken School Readiness Assessment 2002, Psychological Corporation, San Antonio, TX.
36. Panter J.E., Bracken B.A. Validity of the Bracken School Readiness Assessment for predicting first grade readiness. Psychol Sch 2009, 46:397-409.
37. Zimmerman I.L. Preschool language scale 1992, Psychological Corporation, San Antonio, TX. 4th ed.
38. Dunn L.M. Examiner's manual for the PPVT-III, Peabody Picture Vocabulary Test 1997, American Guidance Services, Inc., Circle Pines, MN. 3rd ed.
39. Hoffman D.R., Birch E.E., Birch D.G., Uauy R., Castaneda Y.S., Lapus M.G., et al. Impact of early dietary intake and blood lipid composition of long-chain polyunsaturated fatty acids on later visual development. J Pediatr Gastroenterol Nutr 2000, 31:540-553.
40. Pancsofar N., Vernon-Feagans L. Mother and father language input to young children: contributions to later language development. J Appl Dev Psychol 2006, 27:571-587.
41. Rosner B. Fundamental of biostatistics 1990, PWS-Kent Publishing, Boston, MA.
42. Sénéchal M., LeFevre J. Parental involvement in the development of children's reading skill: a 5-year longitudinal study. Child Dev 2002, 73:445-460.
43. NICHD Early child care and children's development prior to school entry. Am Educ Res J 2002, 39:133-164.
44. NICHD Early child care and children's development in the primary grades: follow up results from the NICHD study of early child care. Am Educ Res J 2005, 42:537-570.
45. Fewtrell M.S., Abbott R.A., Kennedy K., Singhal A., Morley R., Caine E., et al. Randomized, double-blind trial of long-chain polyunsaturated fatty acid supplementation with fish oil and borage oil in preterm infants. J Pediatr 2004, 144:471-479.
46. Hoffman D.R., Boettcher J.A., Diersen-Schade D.A. Toward optimizing vision and cognition in term infants by dietary docosahexaenoic and arachidonic acid supplementation: a review of randomized controlled trials. Prostaglandins Leukot Essent Fatty Acids 2009, 81:151-158.
47. Rupp H., Wagner D., Rupp T., Schulte L.M., Maisch B. Risk stratification by the "EPA+DHA level" and the "EPA/AA ratio" focus on anti-inflammatory and antiarrhythmogenic effects of long-chain omega-3 fatty acids. Herz 2004, 29:673-685.
48. Hoffman D.R., Castañeda Y.S., Garfield S., Ferguson P., Birch E.E. Four-year neurodevelopmental outcomes following a randomized trial of long-chain polyunsaturated fatty acid (LCP) supplementation during the first 12months of life. FASEB J 2008, 22(Suppl.):736.
49. Birch E.E., Garfield S., Castaneda Y., Hughbanks-Wheaton D., Uauy R., Hoffman D. Visual acuity and cognitive outcomes at 4years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula. Early Hum Dev 2007, 83:279-284.