메뉴 건너뛰기




Volumn 18, Issue 8, 2012, Pages 763-770

Efficacy of short-term adjunctive subantimicrobial dose doxycycline in diabetic patients - randomized study

Author keywords

Diabetes mellitus; Host modulation therapy; Matrix metalloproteinase; Periodontitis; Scaling and root planing; Subantimicrobial dose doxycycline

Indexed keywords

DOXYCYCLINE; HEMOGLOBIN A1C; NEUTROPHIL COLLAGENASE; PLACEBO;

EID: 84866863512     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/j.1601-0825.2012.01943.x     Document Type: Article
Times cited : (29)

References (51)
  • 1
    • 0016655811 scopus 로고
    • Problems and proposals for recording gingivitis and plaque
    • Ainamo J, Bay I (1975). Problems and proposals for recording gingivitis and plaque. Int Dent J25: 229-235.
    • (1975) Int Dent J , vol.25 , pp. 229-235
    • Ainamo, J.1    Bay, I.2
  • 2
    • 0029285987 scopus 로고
    • Single-blind studies of the effects of improved periodontal health on metabolic control in type 1 diabetes mellitus
    • Aldridge JP, Lester V, Watts TLP, Collins A, Viberti G, Wilson RF (1995). Single-blind studies of the effects of improved periodontal health on metabolic control in type 1 diabetes mellitus. J Clin Periodontol22: 271-275.
    • (1995) J Clin Periodontol , vol.22 , pp. 271-275
    • Aldridge, J.P.1    Lester, V.2    Watts, T.L.P.3    Collins, A.4    Viberti, G.5    Wilson, R.F.6
  • 3
    • 79951886480 scopus 로고    scopus 로고
    • Diabetes mellitus-associated periodontitis: differences between type 1 and type 2 diabetes mellitus
    • Aspriello SD, Zizzi A, Tirabassi G et al (2011). Diabetes mellitus-associated periodontitis: differences between type 1 and type 2 diabetes mellitus. J Periodontal Res46: 164-169.
    • (2011) J Periodontal Res , vol.46 , pp. 164-169
    • Aspriello, S.D.1    Zizzi, A.2    Tirabassi, G.3
  • 4
    • 0033862278 scopus 로고    scopus 로고
    • Treatment with subantimicrobial dose doxycycline improves the efficacy of scaling and root planing in patients with adult periodontitis
    • Caton JG, Ciancio SG, Blieden TM et al (2000). Treatment with subantimicrobial dose doxycycline improves the efficacy of scaling and root planing in patients with adult periodontitis. J Periodontol71: 521-532.
    • (2000) J Periodontol , vol.71 , pp. 521-532
    • Caton, J.G.1    Ciancio, S.G.2    Blieden, T.M.3
  • 5
    • 0034186228 scopus 로고    scopus 로고
    • Matrix metalloproteinase-8 levels and elastase activities in gingival crevicular fluid from chronic adult periodontitis patients
    • Chen HY, Cox SW, Eley BM, Mantyla R, Ronka H, Sorsa T (2000). Matrix metalloproteinase-8 levels and elastase activities in gingival crevicular fluid from chronic adult periodontitis patients. J Clin Periodontol27: 366-369.
    • (2000) J Clin Periodontol , vol.27 , pp. 366-369
    • Chen, H.Y.1    Cox, S.W.2    Eley, B.M.3    Mantyla, R.4    Ronka, H.5    Sorsa, T.6
  • 6
    • 77649198937 scopus 로고    scopus 로고
    • Association of periodontal parameters with metabolic level and systemic inflammatory markers in patients with type 2 diabetes
    • Chen L, Wei B, Li J et al (2010). Association of periodontal parameters with metabolic level and systemic inflammatory markers in patients with type 2 diabetes. J Periodontol81: 364-371.
    • (2010) J Periodontol , vol.81 , pp. 364-371
    • Chen, L.1    Wei, B.2    Li, J.3
  • 7
    • 1542653032 scopus 로고    scopus 로고
    • Effects of sub-antimicrobial dose doxycycline therapy on crevicular fluid MMP-8, and gingival tissue MMP-9, TIMP-1 and IL-6 levels in chronic periodontitis
    • Choi DH, Moon IS, Choi BK et al (2004). Effects of sub-antimicrobial dose doxycycline therapy on crevicular fluid MMP-8, and gingival tissue MMP-9, TIMP-1 and IL-6 levels in chronic periodontitis. J Periodontal Res39: 20-26.
    • (2004) J Periodontal Res , vol.39 , pp. 20-26
    • Choi, D.H.1    Moon, I.S.2    Choi, B.K.3
  • 8
    • 0031992956 scopus 로고    scopus 로고
    • Healing response to non-surgical periodontal therapy in patients with diabetes mellitus: clinical, microbiological, and immunological results
    • Christgau M, Palitzsch KD, Schmalz G, Kreiner U, Frenzel S (1998). Healing response to non-surgical periodontal therapy in patients with diabetes mellitus: clinical, microbiological, and immunological results. J Clin Periodontol25: 112-124.
    • (1998) J Clin Periodontol , vol.25 , pp. 112-124
    • Christgau, M.1    Palitzsch, K.D.2    Schmalz, G.3    Kreiner, U.4    Frenzel, S.5
  • 10
    • 0030138722 scopus 로고    scopus 로고
    • The "cyclic" regimen of low-dose doxycycline for adult periodontitis: a preliminary study
    • Crout RJ, Lee HM, Schroeder K et al (1996). The "cyclic" regimen of low-dose doxycycline for adult periodontitis: a preliminary study. J Periodontol67: 506-514.
    • (1996) J Periodontol , vol.67 , pp. 506-514
    • Crout, R.J.1    Lee, H.M.2    Schroeder, K.3
  • 11
    • 47749133006 scopus 로고    scopus 로고
    • Clinical and laboratory evaluations of non-surgical periodontal treatment in subjects with diabetes mellitus
    • da Cruz GA, de Toledo S, Sallum EA et al (2008). Clinical and laboratory evaluations of non-surgical periodontal treatment in subjects with diabetes mellitus. J Periodontol79: 1150-1157.
    • (2008) J Periodontol , vol.79 , pp. 1150-1157
    • da Cruz, G.A.1    de Toledo, S.2    Sallum, E.A.3
  • 12
    • 77955863393 scopus 로고    scopus 로고
    • Evaluation of subantimicrobial dose doxycycline as an adjunct to scaling and root planing in chronic periodontitis patients with diabetes: a randomized, placebo-controlled clinical trial
    • Deo V, Gupta S, Bhongade ML, Jaiswal R (2010). Evaluation of subantimicrobial dose doxycycline as an adjunct to scaling and root planing in chronic periodontitis patients with diabetes: a randomized, placebo-controlled clinical trial. J Contemp Dent Pract11: 9-16.
    • (2010) J Contemp Dent Pract , vol.11 , pp. 9-16
    • Deo, V.1    Gupta, S.2    Bhongade, M.L.3    Jaiswal, R.4
  • 13
    • 1542360543 scopus 로고    scopus 로고
    • The effect of adjunctive low-dose doxycycline therapy on clinical parameters and gingival crevicular fluid matrix metalloproteinase-8 levels in chronic periodontitis
    • Emingil G, Atilla G, Sorsa T, Luoto H, Kirilmaz L, Baylas H (2004). The effect of adjunctive low-dose doxycycline therapy on clinical parameters and gingival crevicular fluid matrix metalloproteinase-8 levels in chronic periodontitis. J Periodontol75: 106-115.
    • (2004) J Periodontol , vol.75 , pp. 106-115
    • Emingil, G.1    Atilla, G.2    Sorsa, T.3    Luoto, H.4    Kirilmaz, L.5    Baylas, H.6
  • 14
    • 80054098536 scopus 로고    scopus 로고
    • Sub-antimicrobial doxycycline for periodontitis reduces hemoglobin A1c in subjects with type 2 diabetes: a pilot study
    • Engebretson SP, Hey-Hadavi J (2011). Sub-antimicrobial doxycycline for periodontitis reduces hemoglobin A1c in subjects with type 2 diabetes: a pilot study. Pharmacol Res64: 624-629.
    • (2011) Pharmacol Res , vol.64 , pp. 624-629
    • Engebretson, S.P.1    Hey-Hadavi, J.2
  • 15
    • 0021677785 scopus 로고
    • Tetracyclines inhibit tissue collagenases activity. A new mechanism in the treatment of periodontal disease
    • Golub LM, Ramamurthy N, McNamara TF et al (1984). Tetracyclines inhibit tissue collagenases activity. A new mechanism in the treatment of periodontal disease. J Periodontal Res19: 651-655.
    • (1984) J Periodontal Res , vol.19 , pp. 651-655
    • Golub, L.M.1    Ramamurthy, N.2    McNamara, T.F.3
  • 16
    • 0025686083 scopus 로고
    • Low-dose doxycykline therapy: effect on gingival and crevicular fluid collagenase activity in humans
    • Golub LM, Ciancio S, Ramamurthy N, Leung M, McNamara TF (1990). Low-dose doxycykline therapy: effect on gingival and crevicular fluid collagenase activity in humans. J Periodontal Res25: 321-330.
    • (1990) J Periodontal Res , vol.25 , pp. 321-330
    • Golub, L.M.1    Ciancio, S.2    Ramamurthy, N.3    Leung, M.4    McNamara, T.F.5
  • 17
    • 0032200444 scopus 로고    scopus 로고
    • Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms
    • Golub LM, Lee HM, Ryan ME, Giannobile WV, Payne J, Sorsa T (1998). Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms. Adv Dent Res12: 12-26.
    • (1998) Adv Dent Res , vol.12 , pp. 12-26
    • Golub, L.M.1    Lee, H.M.2    Ryan, M.E.3    Giannobile, W.V.4    Payne, J.5    Sorsa, T.6
  • 18
    • 0035256275 scopus 로고    scopus 로고
    • Adjunctive treatment with subantimicrobial doses of doxycycline: effects on gingival fluid collagenase activity and attachment loss in adult periodontitis
    • Golub LM, McNamara TF, Ryan ME et al (2001). Adjunctive treatment with subantimicrobial doses of doxycycline: effects on gingival fluid collagenase activity and attachment loss in adult periodontitis. J Clin Periodontol28: 146-156.
    • (2001) J Clin Periodontol , vol.28 , pp. 146-156
    • Golub, L.M.1    McNamara, T.F.2    Ryan, M.E.3
  • 19
    • 49149123468 scopus 로고    scopus 로고
    • Subantimicrobial-dose doxycycline modulates gingival crevicular fluid biomarkers of periodontitis in postmenopausal osteopenic women
    • Golub LM, Lee HM, Stoner JA et al (2008). Subantimicrobial-dose doxycycline modulates gingival crevicular fluid biomarkers of periodontitis in postmenopausal osteopenic women. J Periodontol79: 1409-1418.
    • (2008) J Periodontol , vol.79 , pp. 1409-1418
    • Golub, L.M.1    Lee, H.M.2    Stoner, J.A.3
  • 20
    • 0030746716 scopus 로고    scopus 로고
    • Treatment of periodontal disease in diabetics reduces glycated hemoglobin
    • Grossi SG, Skrepcinski FB, DeCaro T et al (1997). Treatment of periodontal disease in diabetics reduces glycated hemoglobin. J Periodontol68: 713-719.
    • (1997) J Periodontol , vol.68 , pp. 713-719
    • Grossi, S.G.1    Skrepcinski, F.B.2    DeCaro, T.3
  • 21
    • 78249233559 scopus 로고    scopus 로고
    • Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: a longitudinal study
    • Hernandez M, Gamonal J, Tervahartiala T et al (2010). Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: a longitudinal study. J Periodontol81: 1644-1652.
    • (2010) J Periodontol , vol.81 , pp. 1644-1652
    • Hernandez, M.1    Gamonal, J.2    Tervahartiala, T.3
  • 22
    • 77953196153 scopus 로고    scopus 로고
    • Crevicular fluid matrix metalloproteinase-8, -13, and TIMP-1 levels in type 2 diabetics
    • Kardeşler L, Biyikoǧlu B, Çetinkalp Ş, Pitkala M, Sorsa T, Buduneli N (2010a). Crevicular fluid matrix metalloproteinase-8, -13, and TIMP-1 levels in type 2 diabetics. Oral Dis16: 476-481.
    • (2010) Oral Dis , vol.16 , pp. 476-481
    • Kardeşler, L.1    Biyikoǧlu, B.2    Çetinkalp, S.3    Pitkala, M.4    Sorsa, T.5    Buduneli, N.6
  • 23
    • 77649201584 scopus 로고    scopus 로고
    • Adipokines and inflammatory mediators after initial periodontal treatment in patients with type 2 diabetes and chronic periodontitis
    • Kardeşler L, Buduneli N, Çetinkalp Ş, Kinane DF (2010b). Adipokines and inflammatory mediators after initial periodontal treatment in patients with type 2 diabetes and chronic periodontitis. J Periodontol81: 24-33.
    • (2010) J Periodontol , vol.81 , pp. 24-33
    • Kardeşler, L.1    Buduneli, N.2    Çetinkalp, S.3    Kinane, D.F.4
  • 24
    • 77958581326 scopus 로고    scopus 로고
    • The effect of full-mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial
    • Khader YS, Al Habashneh R, Al Malalheh M, Bataineh A (2010). The effect of full-mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial. J Periodontal Res45: 741-747.
    • (2010) J Periodontal Res , vol.45 , pp. 741-747
    • Khader, Y.S.1    Al Habashneh, R.2    Al Malalheh, M.3    Bataineh, A.4
  • 25
    • 28244477069 scopus 로고    scopus 로고
    • The use of locally-delivered chlorhexidine in the treatment of periodontitis. Clinical results
    • Killoy WJ (1998). The use of locally-delivered chlorhexidine in the treatment of periodontitis. Clinical results. J Clin Periodontol25: 953-958.
    • (1998) J Clin Periodontol , vol.25 , pp. 953-958
    • Killoy, W.J.1
  • 26
    • 0141783728 scopus 로고    scopus 로고
    • Changes in gingival crevicular fluid matrix metalloproteinase-8 levels during periodontal treatment and maintenance
    • Kinane DF, Darby IB, Said S et al (2003). Changes in gingival crevicular fluid matrix metalloproteinase-8 levels during periodontal treatment and maintenance. J Periodontal Res38: 400-404.
    • (2003) J Periodontal Res , vol.38 , pp. 400-404
    • Kinane, D.F.1    Darby, I.B.2    Said, S.3
  • 27
    • 16244372028 scopus 로고    scopus 로고
    • The effect of improved periodontal health on metabolic control in type diabetes mellitus
    • Kiran M, Arpak N, Unsal E, Erdogan MF (2005). The effect of improved periodontal health on metabolic control in type diabetes mellitus. J Clin Periodontol32: 266-272.
    • (2005) J Clin Periodontol , vol.32 , pp. 266-272
    • Kiran, M.1    Arpak, N.2    Unsal, E.3    Erdogan, M.F.4
  • 28
    • 33751265226 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases (MMP-8 and -9) in chronic periodontitis patients with and without diabetes mellitus
    • Kumar MS, Vamsi G, Sripriya R, Sehgal PK (2006). Expression of matrix metalloproteinases (MMP-8 and -9) in chronic periodontitis patients with and without diabetes mellitus. J Periodontol77: 1803-1808.
    • (2006) J Periodontol , vol.77 , pp. 1803-1808
    • Kumar, M.S.1    Vamsi, G.2    Sripriya, R.3    Sehgal, P.K.4
  • 30
    • 10944256349 scopus 로고    scopus 로고
    • Effect of subantimicrobial dose doxycycline as an effective adjunct to scaling and root planing
    • Lee JY, Lee YM, Shin SY et al (2004). Effect of subantimicrobial dose doxycycline as an effective adjunct to scaling and root planing. J Periodontol75: 1500-1508.
    • (2004) J Periodontol , vol.75 , pp. 1500-1508
    • Lee, J.Y.1    Lee, Y.M.2    Shin, S.Y.3
  • 31
    • 78650077604 scopus 로고    scopus 로고
    • Oral rinse MMP-8 point-of-care immuno test identifies patients with strong periodontal inflammatory burden
    • Leppilahti J, Ahonen MM, Hernández M et al (2011). Oral rinse MMP-8 point-of-care immuno test identifies patients with strong periodontal inflammatory burden. Oral Dis17: 115-122.
    • (2011) Oral Dis , vol.17 , pp. 115-122
    • Leppilahti, J.1    Ahonen, M.M.2    Hernández, M.3
  • 32
    • 74049098607 scopus 로고    scopus 로고
    • Gingival crevicular fluid levels of MMP-8, MMP-9, TIMP-2, and MPO decrease after periodontal therapy
    • Marcaccini AM, Meschiari CA, Zuardi LR et al (2010). Gingival crevicular fluid levels of MMP-8, MMP-9, TIMP-2, and MPO decrease after periodontal therapy. J Clin Periodontol37: 180-190.
    • (2010) J Clin Periodontol , vol.37 , pp. 180-190
    • Marcaccini, A.M.1    Meschiari, C.A.2    Zuardi, L.R.3
  • 33
    • 0026929998 scopus 로고
    • The relationship between reduction in periodontal inflammation and diabetes control: a report of 9 cases
    • Miller LS, Manwell MA, Newbold D et al (1992). The relationship between reduction in periodontal inflammation and diabetes control: a report of 9 cases. J Periodontol63: 843-848.
    • (1992) J Periodontol , vol.63 , pp. 843-848
    • Miller, L.S.1    Manwell, M.A.2    Newbold, D.3
  • 34
    • 34548572150 scopus 로고    scopus 로고
    • Effect of non-surgical periodontal therapy on clinical and immunological response and glycaemic control in type 2 diabetic patients with moderate periodontitis
    • Navarro-Sanchez AB, Faria-Almeida R, Bascones-Martinez A (2007). Effect of non-surgical periodontal therapy on clinical and immunological response and glycaemic control in type 2 diabetic patients with moderate periodontitis. J Clin Periodontol34: 835-843.
    • (2007) J Clin Periodontol , vol.34 , pp. 835-843
    • Navarro-Sanchez, A.B.1    Faria-Almeida, R.2    Bascones-Martinez, A.3
  • 35
    • 63149176683 scopus 로고    scopus 로고
    • Dose-response relationship between periodontal inflamed surface area and HbA1c in type 2 diabetics
    • Nesse W, Linde A, Abbas F et al (2009). Dose-response relationship between periodontal inflamed surface area and HbA1c in type 2 diabetics. J Clin Periodontol36: 295-300.
    • (2009) J Clin Periodontol , vol.36 , pp. 295-300
    • Nesse, W.1    Linde, A.2    Abbas, F.3
  • 37
    • 78650085459 scopus 로고    scopus 로고
    • Smoking and matrix metalloproteinases, neutrophil elastase and myeloperoxidase in chronic periodontitis
    • Özçaka Ö, Biçakci N, Pussinen P, Sorsa T, Köse T, Buduneli N (2011). Smoking and matrix metalloproteinases, neutrophil elastase and myeloperoxidase in chronic periodontitis. Oral Dis17: 68-76.
    • (2011) Oral Dis , vol.17 , pp. 68-76
    • Özçaka, O.1    Biçakci, N.2    Pussinen, P.3    Sorsa, T.4    Köse, T.5    Buduneli, N.6
  • 38
    • 4644370370 scopus 로고    scopus 로고
    • Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: a multicenter trial
    • Preshaw PM, Hefti AF, Novak MJ et al (2004). Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: a multicenter trial. J Periodontol75: 1068-1076.
    • (2004) J Periodontol , vol.75 , pp. 1068-1076
    • Preshaw, P.M.1    Hefti, A.F.2    Novak, M.J.3
  • 39
    • 25144510575 scopus 로고    scopus 로고
    • The effect of periodontal therapy on uncontrolled type 2 diabetes mellitus in older subjects
    • Promsudthi A, Pimapansri S, Deerochanawong C, Kanchanavasita W (2005). The effect of periodontal therapy on uncontrolled type 2 diabetes mellitus in older subjects. Oral Dis11: 293-298.
    • (2005) Oral Dis , vol.11 , pp. 293-298
    • Promsudthi, A.1    Pimapansri, S.2    Deerochanawong, C.3    Kanchanavasita, W.4
  • 40
    • 0029353884 scopus 로고
    • Full- vs. partial-mouth disinfection in the treatment of periodontal infections: short-term clinical and microbiological observations
    • Quirynen M, Bollen CM, Vandekerckhove BN, Dekeyser C, Papaioannou W, Eyssen H (1995). Full- vs. partial-mouth disinfection in the treatment of periodontal infections: short-term clinical and microbiological observations. J Dent Res74: 1459-1467.
    • (1995) J Dent Res , vol.74 , pp. 1459-1467
    • Quirynen, M.1    Bollen, C.M.2    Vandekerckhove, B.N.3    Dekeyser, C.4    Papaioannou, W.5    Eyssen, H.6
  • 41
    • 0242383361 scopus 로고    scopus 로고
    • Effect of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes mellitus
    • Rodrigues DC, Tabe MJ, Novaes AB, Souza SL, Grisi MF (2003). Effect of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes mellitus. J Periodontol74: 1361-1367.
    • (2003) J Periodontol , vol.74 , pp. 1361-1367
    • Rodrigues, D.C.1    Tabe, M.J.2    Novaes, A.B.3    Souza, S.L.4    Grisi, M.F.5
  • 42
    • 0036482285 scopus 로고    scopus 로고
    • Defining the relationship between plasma glucose and HbA1c: analysis of glucose profile and HbA1c in the diabetes control and complications trial
    • Rohlfing CL, Wiedemeyer HM, Little RR, England JD, Tennill A, Goldstein DE (2002). Defining the relationship between plasma glucose and HbA1c: analysis of glucose profile and HbA1c in the diabetes control and complications trial. Diabetes Care25: 275-278.
    • (2002) Diabetes Care , vol.25 , pp. 275-278
    • Rohlfing, C.L.1    Wiedemeyer, H.M.2    Little, R.R.3    England, J.D.4    Tennill, A.5    Goldstein, D.E.6
  • 43
    • 77955949371 scopus 로고    scopus 로고
    • Expression of periodontal interleukin-6 protein is increased across patients with neither periodontal disease nor diabetes, patients with periodontal disease alone and patients with both diseases
    • Ross JH, Hardy DC, Schuyler CA, Slate EH, Mize TW, Huang Y (2010). Expression of periodontal interleukin-6 protein is increased across patients with neither periodontal disease nor diabetes, patients with periodontal disease alone and patients with both diseases. J Periodontal Res45: 688-694.
    • (2010) J Periodontal Res , vol.45 , pp. 688-694
    • Ross, J.H.1    Hardy, D.C.2    Schuyler, C.A.3    Slate, E.H.4    Mize, T.W.5    Huang, Y.6
  • 44
    • 80655129361 scopus 로고    scopus 로고
    • Long-term efficacy of subantimicrobial-dose doxycycline as an adjunctive treatment to scaling and root planing: a systematic review and meta-analysis
    • Sgolastra F, Petrucci A, Gatto R, Giannoni M, Monaco A (2011). Long-term efficacy of subantimicrobial-dose doxycycline as an adjunctive treatment to scaling and root planing: a systematic review and meta-analysis. J Periodontol82: 1570-1581.
    • (2011) J Periodontol , vol.82 , pp. 1570-1581
    • Sgolastra, F.1    Petrucci, A.2    Gatto, R.3    Giannoni, M.4    Monaco, A.5
  • 45
    • 77958531151 scopus 로고    scopus 로고
    • Type 1 diabetes predisposes to enhanced gingival leukocyte margination and macromolecule extravasation in vivo
    • Sima C, Rhourida K, Van Dyke TE, Gyurko R (2010). Type 1 diabetes predisposes to enhanced gingival leukocyte margination and macromolecule extravasation in vivo. J Periodontal Res45: 748-756.
    • (2010) J Periodontal Res , vol.45 , pp. 748-756
    • Sima, C.1    Rhourida, K.2    Van Dyke, T.E.3    Gyurko, R.4
  • 46
    • 0024117565 scopus 로고
    • Comparison of interstitial collagenases from human gingival, sulcular fluid and polymorphonuclear leukocytes
    • Sorsa T, Uitto VJ, Suomalainen K, Vauhkinen M, Lindy S (1988). Comparison of interstitial collagenases from human gingival, sulcular fluid and polymorphonuclear leukocytes. J Periodontal Res23: 386-393.
    • (1988) J Periodontal Res , vol.23 , pp. 386-393
    • Sorsa, T.1    Uitto, V.J.2    Suomalainen, K.3    Vauhkinen, M.4    Lindy, S.5
  • 47
    • 73649134293 scopus 로고    scopus 로고
    • Detection of gingival crevicular fluid MMP-8 levels with different laboratory and chair-side methods
    • Sorsa T, Hernández M, Leppilahti J, Munjal S, Netuschil L, Mäntylä P (2010). Detection of gingival crevicular fluid MMP-8 levels with different laboratory and chair-side methods. Oral Dis16: 39-45.
    • (2010) Oral Dis , vol.16 , pp. 39-45
    • Sorsa, T.1    Hernández, M.2    Leppilahti, J.3    Munjal, S.4    Netuschil, L.5    Mäntylä, P.6
  • 48
    • 0035316165 scopus 로고    scopus 로고
    • The effect of periodontal treatment on glycemic control in patients with type 2 diabetes mellitus
    • Stewart JE, Pager KA, Friedlander AH, Zadeh HH (2001). The effect of periodontal treatment on glycemic control in patients with type 2 diabetes mellitus. J Clin Periodontol28: 306-310.
    • (2001) J Clin Periodontol , vol.28 , pp. 306-310
    • Stewart, J.E.1    Pager, K.A.2    Friedlander, A.H.3    Zadeh, H.H.4
  • 49
    • 58449108032 scopus 로고    scopus 로고
    • Resolution of periodontal inflammation does not guarantee improved glycemic control in type 1 diabetic subjects
    • Tervonen T, Lamminsalo S, Hiltunen L, Raunio T, Knuuttila M (2009). Resolution of periodontal inflammation does not guarantee improved glycemic control in type 1 diabetic subjects. J Clin Periodontol36: 51-57.
    • (2009) J Clin Periodontol , vol.36 , pp. 51-57
    • Tervonen, T.1    Lamminsalo, S.2    Hiltunen, L.3    Raunio, T.4    Knuuttila, M.5
  • 50
    • 77955371777 scopus 로고    scopus 로고
    • Effects of scaling and root planing and subantimicrobial dose doxycycline on gingival crevicular fluid levels of matrix metalloproteinase-8, -13 and serum levels of HsCRP in patients with chronic periodontitis
    • Tüter G, Serdar M, Kurtis B et al (2010). Effects of scaling and root planing and subantimicrobial dose doxycycline on gingival crevicular fluid levels of matrix metalloproteinase-8, -13 and serum levels of HsCRP in patients with chronic periodontitis. J Periodontol81: 1132-1139.
    • (2010) J Periodontol , vol.81 , pp. 1132-1139
    • Tüter, G.1    Serdar, M.2    Kurtis, B.3
  • 51
    • 0028521265 scopus 로고
    • Diabetes as a modifier of periodontal disease expression
    • Yalda B, Offenbacher S, Collins G (1994). Diabetes as a modifier of periodontal disease expression. Periodontol 20006: 37-49.
    • (1994) Periodontol 2000 , vol.6 , pp. 37-49
    • Yalda, B.1    Offenbacher, S.2    Collins, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.