Hepatic miR-29ab1 expression modulates chronic hepatic injury

Journal of Cellular and Molecular Medicine

Volumn 16, Issue 11, 2012, Pages 2647-2654

  Kogure, Takayuki ^a,b   Costinean, Stefan ^a   Yan, Irene ^b   Braconi, Chiara ^a   Croce, Carlo ^a   Patel, Tushar ^a,b  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Fibrosis; Liver cancer; Transgenic

Indexed keywords

CARBON TETRACHLORIDE; MICRORNA; MIRN29 MICRORNA, MOUSE;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; CHRONIC DISEASE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; LIVER CELL; LIVER CIRRHOSIS; MORTALITY; MOUSE; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CARBON TETRACHLORIDE; CHRONIC DISEASE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEPATOCYTES; LIVER CIRRHOSIS; MICE; MICE, KNOCKOUT; MICRORNAS;

MUS;

EID: 84866854752     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2012.01578.x     Document Type: Article

References (27)

1. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116: 281-97.
2. Kim VN. MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol. 2005; 6: 376-85.
3. Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet. 2010; 11: 597-610.
4. Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005; 120: 15-20.
5. Xiong Y, Fang JH, Yun JP, et al. Effects of microRNA-29 on apoptosis, tumourigenicity, and prognosis of hepatocellular carcinoma. Hepatology. 2010; 51: 836-45.
6. Roderburg C, Urban GW, Bettermann K, et al. Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis. Hepatology. 2011; 53: 209-18.
7. Jiang X, Tsitsiou E, Herrick SE, Lindsay MA. MicroRNAs and the regulation of fibrosis. FEBS J. 2010; 277: 2015-21.
8. Maurer B, Stanczyk J, Jungel A, et al. MicroRNA-29, a key regulator of collagen expression in systemic sclerosis. Arthritis Rheum. 2010; 62: 1733-43.
9. Cushing L, Kuang PP, Qian J, et al. MIR-29 is a major regulator of genes associated with pulmonary fibrosis. Am J Respir Cell Mol Biol. 2010; 45: 287-94.
10. van Rooij E, Sutherland LB, Thatcher JE, et al. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci USA. 2008; 105: 13027-32.
11. Pekarsky Y, Santanam U, Cimmino A, et al. Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res. 2006; 66: 11590-3.
12. Mott JL, Kobayashi S, Bronk SF, Gores GJ. mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene. 2007; 26: 6133-40.
13. Park SY, Lee JH, Ha M, et al. miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42. Nat Struct Mol Biol. 2009; 16: 23-9.
14. Mott JL, Kurita S, Cazanave SC, et al. Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB. J Cell Biochem. 2010; 110: 1155-64.
15. Kwiecinski M, Noetel A, Elfimova N, et al. Hepatocyte growth factor (HGF) inhibits collagen I and IV synthesis in hepatic stellate cells by miRNA-29 induction. PLoS One. 2011; 6: e24568.
16. Postic C, Shiota M, Niswender KD, et al. Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase. J Biol Chem. 1999; 274: 305-15.
17. Brault V, Moore R, Kutsch S, et al. Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development. 2001; 128: 1253-64.
18. Zeisberg M, Yang C, Martino M, et al. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J Biol Chem. 2007; 282: 23337-47.
19. Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc. 2008; 3: 1101-8.
20. Irizarry RA, Bolstad BM, Collin F, et al. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res. 2003; 31: e15.
21. Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009; 4: 44-57.
22. Friedman SL. Evolving challenges in hepatic fibrosis. Nat Rev Gastroenterol Hepatol. 2010; 7: 425-36.
23. Fabbri M, Garzon R, Cimmino A, et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA. 2007; 104: 15805-10.
24. Filkowski JN, Ilnytskyy Y, Tamminga J, et al. Hypomethylation and genome instability in the germline of exposed parents and their progeny is associated with altered miRNA expression. Carcinogenesis. 2010; 31: 1110-5.
25. Vacher J, Camper SA, Krumlauf R, et al. raf regulates the postnatal repression of the mouse alpha-fetoprotein gene at the posttranscriptional level. Mol Cell Biol. 1992; 12: 856-64.
26. Matouk IJ, DeGroot N, Mezan S, et al. The H19 non-coding RNA is essential for human tumour growth. PLoS One 2007; 2: e845.
27. Yamamoto Y, Nishikawa Y, Tokairin T, et al. Increased expression of H19 non-coding mRNA follows hepatocyte proliferation in the rat and mouse. J Hepatol. 2004; 40: 808-14.