Spartan/C1orf124 is important to prevent UV-induced mutagenesis

Cell Cycle

Volumn 11, Issue 18, 2012, Pages 3395-3402

  Machida, Yuka ^a   Kim, Myoung Shin ^a   Machida, Yuichi J ^a  

^a Mayo Clinic   (United States)

Author keywords

C1orf124; DNA damage; Mutagenesis; PCNA; PIP box; Spartan; Ubiquitin; UBZ

Indexed keywords

CYCLINE; NUCLEAR PROTEIN; RAD18 PROTEIN; SPARTAN PROTEIN; UBIQUITIN; UBZ4 UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PIP BOX; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; RADIATION MUTAGENESIS; ULTRAVIOLET RADIATION;

EID: 84866745325     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.21694     Document Type: Article

References (37)

1. Chang DJ, Cimprich KA. DNA damage tolerance: when it's OK to make mistakes. Nat Chem Biol 2009; 5:82-90; PMID:19148176; http://dx.doi.org/10.1038/ nchembio.139.
2. Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 2002; 419:135-41; PMID:12226657; http://dx.doi.org/10.1038/nature00991.
3. Kannouche PL, Wing J, Lehmann AR. Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol Cell 2004; 14:491-500; PMID:15149598; http://dx.doi.org/10.1016/S1097-2765(04)00259-X.
4. Watanabe K, Tateishi S, Kawasuji M, Tsurimoto T, Inoue H, Yamaizumi M. Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination. EMBO J 2004; 23:3886-96; PMID:15359278; http://dx.doi.org/10.1038/sj.emboj.7600383.
5. Bienko M, Green CM, Crosetto N, Rudolf F, Zapart G, Coull B, et al. Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Science 2005; 310:1821-4; PMID:16357261; http://dx.doi.org/10.1126/ science.1120615.
6. Kannouche PL, Wing J, Lehmann AR. Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol Cell 2004; 14:491-500; PMID:15149598; http://dx.doi.org/10.1016/S1097-2765(04)00259-X.
7. Guo C, Tang TS, Bienko M, Dikic I, Friedberg EC. Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance. J Biol Chem 2008; 283:4658-64; PMID:18162470; http://dx.doi.org/10.1074/jbc. M709275200.
8. Plosky BS, Vidal AE, Fernández de Henestrosa AR, McLenigan MP, McDonald JP, Mead S, et al. Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin. EMBO J 2006; 25:2847-55; PMID:16763556; http://dx.doi.org/10.1038/sj.emboj.7601178.
9. Sale JE, Lehmann AR, Woodgate R. Y-family DNA polymerases and their role in tolerance of cellular DNA damage. Nat Rev Mol Cell Biol 2012; 13:141-52; PMID:22358330; http://dx.doi.org/10.1038/nrm3289.
10. Motegi A, Liaw HJ, Lee KY, Roest HP, Maas A, Wu X, et al. Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks. Proc Natl Acad Sci USA 2008; 105:12411-6; PMID:18719106; http://dx.doi.org/10.1073/pnas.0805685105.
11. Motegi A, Sood R, Moinova H, Markowitz SD, Liu PP, Myung K. Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination. J Cell Biol 2006; 175:703-8; PMID:17130289; http://dx.doi.org/10.1083/jcb.200606145.
12. Unk I, Hajdú I, Fátyol K, Szakál B, Blastyák A, Bermudez V, et al. Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen. Proc Natl Acad Sci USA 2006; 103:18107-12; PMID:17108083; http://dx.doi.org/10.1073/pnas. 0608595103.
13. Bergink S, Jentsch S. Principles of ubiquitin and SUMO modifications in DNA repair. Nature 2009; 458:461-7; PMID:19325626; http://dx.doi.org/10.1038/ nature07963.
14. Hofmann K. Ubiquitin-binding domains and their role in the DNA damage response. DNA Repair (Amst) 2009; 8:544-56; PMID:19213613; http://dx.doi.org/10. 1016/j.dnarep.2009.01.003.
15. Kratz K, Schöpf B, Kaden S, Sendoel A, Eberhard R, Lademann C, et al. Deficiency of FANCD2- associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents. Cell 2010; 142:77-88; PMID:20603016; http://dx.doi.org/10.1016/j.cell.2010.06.022.
16. Liu T, Ghosal G, Yuan J, Chen J, Huang J. FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. Science 2010; 329:693-6; PMID:20671156; http://dx.doi.org/10.1126/science.1192656.
17. MacKay C, Déclais AC, Lundin C, Agostinho A, Deans AJ, MacArtney TJ, et al. Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell 2010; 142:65-76; PMID:20603015; http://dx.doi.org/10.1016/j.cell.2010.06.021.
18. Shereda RD, Machida Y, Machida YJ. Human KIAA1018/FAN1 localizes to stalled replication forks via its ubiquitin-binding domain. Cell Cycle 2010; 9:3977-83; PMID:20935496; http://dx.doi.org/10.4161/cc.9.19.13207.
19. Smogorzewska A, Desetty R, Saito TT, Schlabach M, Lach FP, Sowa ME, et al. A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. Mol Cell 2010; 39:36-47; PMID:20603073; http://dx.doi.org/10.1016/j.molcel.2010.06.023.
20. Crosetto N, Bienko M, Hibbert RG, Perica T, Ambrogio C, Kensche T, et al. Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner. J Biol Chem 2008; 283:35173-85; PMID:18842586; http://dx.doi.org/10.1074/jbc.M803219200.
21. Guo C, Tang TS, Bienko M, Dikic I, Friedberg EC. Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance. J Biol Chem 2008; 283:4658-64; PMID:18162470; http://dx.doi.org/10.1074/jbc. M709275200.
22. Huang J, Huen MS, Kim H, Leung CC, Glover JN, Yu X, et al. RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol 2009; 11:592-603; PMID:19396164; http://dx.doi.org/10.1038/ncb1865.
23. rd, et al. A Ubiquitin-Binding Protein, FAAP20, Links RNF8-Mediated Ubiquitination to the Fanconi Anemia DNA Repair Network. Mol Cell 2012; 47:61-75; PMID:22705371.
24. Leung JW, Wang Y, Fong KW, Huen MS, Li L, Chen J. Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. Proc Natl Acad Sci USA 2012; 109:4491-6; PMID:22396592; http://dx.doi.org/10.1073/pnas.1118720109.
25. Ali AM, Pradhan A, Singh TR, Du C, Li J, Wahengbam K, et al. FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway. Blood 2012; 119:3285-94; PMID:22343915; http://dx.doi.org/10.1182/blood-2011-10-385963.
26. Kim H, Yang K, Dejsuphong D, D'Andrea AD. Regulation of Rev1 by the Fanconi anemia core complex. Nat Struct Mol Biol 2012; 19:164-70; PMID:22266823; http://dx.doi.org/10.1038/nsmb.2222.
27. Centore RC, Yazinski SA, Tse A, Zou L. Spartan/C1orf124, a reader of PCNA ubiquitylation and a regulator of UV-induced DNA damage response. Mol Cell 2012; 46:625-35; PMID:22681887; http://dx.doi.org/10.1016/j.molcel.2012.05.020.
28. Ponting CP. Novel domains and orthologues of eukaryotic transcription elongation factors. Nucleic Acids Res 2002; 30:3643-52; PMID:12202748; http://dx.doi.org/10.1093/nar/gkf498.
29. Moldovan GL, Pfander B, Jentsch S. PCNA, the maestro of the replication fork. Cell 2007; 129:665-79; PMID:17512402; http://dx.doi.org/10.1016/j.cell. 2007.05.003.
30. Colaiácovo MP, Stanfield GM, Reddy KC, Reinke V, Kim SK, Villeneuve AM. A targeted RNAi screen for genes involved in chromosome morphogenesis and nuclear organization in the Caenorhabditis elegans germline. Genetics 2002; 162:113-28; PMID:12242227.
31. Maeda I, Kohara Y, Yamamoto M, Sugimoto A. Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Curr Biol 2001; 11:171-6; PMID:11231151; http://dx.doi.org/10.1016/S0960-9822(01)00052-5.
32. Parris CN, Levy DD, Jessee J, Seidman MM. Proximal and distal effects of sequence context on ultraviolet mutational hotspots in a shuttle vector replicated in xeroderma cells. J Mol Biol 1994; 236:491-502; PMID:8107135; http://dx.doi.org/10.1006/jmbi.1994.1160.
33. Lehmann AR, Niimi A, Ogi T, Brown S, Sabbioneda S, Wing JF, et al. Translesion synthesis: Y-family polymerases and the polymerase switch. DNA Repair (Amst) 2007; 6:891-9; PMID:17363342; http://dx.doi.org/10.1016/j.dnarep. 2007.02.003.
34. Hendel A, Krijger PH, Diamant N, Goren Z, Langerak P, Kim J, et al. PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells. PLoS Genet 2011; 7:e1002262; PMID:21931560; http://dx.doi.org/10.1371/journal.pgen.1002262.
35. Geng L, Huntoon CJ, Karnitz LM. RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network. J Cell Biol 2010; 191:249-57; PMID:20937699; http://dx.doi.org/10.1083/jcb.201005101.
36. Shiomi N, Mori M, Tsuji H, Imai T, Inoue H, Tateishi S, et al. Human RAD18 is involved in S phase-specific single-strand break repair without PCNA monoubiquitination. Nucleic Acids Res 2007; 35:e9; PMID:17158148; http://dx.doi.org/10.1093/nar/gkl979.
37. Despras E, Daboussi F, Hyrien O, Marheineke K, Kannouche PL. ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells. Hum Mol Genet 2010; 19:1690-701; PMID:20123862; http://dx.doi.org/10.1093/hmg/ddq046.