Experimental Models of Hepatic Fibrosis in the Rat

Annals of the Academy of Medicine Singapore

Volumn 28, Issue 1, 1999, Pages 109-111

  Wasser, Shanthi ^a   Tan, C E L ^b  

^a KK WOMEN'S AND CHILDREN'S HOSPITAL   (Singapore)

^b NONE

Author keywords

Alcoholic liver disease; Bile duct ligation; Carbon tetrachloride; Liver cirrhosis

Indexed keywords

ANIMAL; BILIARY CIRRHOSIS; EXPERIMENTAL LIVER CIRRHOSIS; PATHOLOGY; RAT; REVIEW;

ANIMALS; LIVER CIRRHOSIS, BILIARY; LIVER CIRRHOSIS, EXPERIMENTAL; RATS;

EID: 0032612910     PISSN: 03044602     EISSN: 29724066     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Tsukamoto H, Matsuoka M, French S W. Experimental models of hepatic fibrosis: A review. Semin Liver Dis 1990; 10:56-65.
2. Proctor E, Chatamra K. High yield micronodular cirrhosis in the rat. Gastroenterology 1982; 83:1183-90.
3. Risteli J, Kivirikko K A. Intracellular enzymes of collagen biosynthesis in rat liver as a function of age and in hepatic injury induced by dimethylnitrosamine. Biochem J 1976; 158:361-7.
4. Muller A, Macknik F, Zimmerman T, Schubert H. Thioacetamide-induced cirrhosis-like liver lesions in rats - usefulness and reliability of this animal model. Exp Pathol (Jena) 1988; 34:229-36.
5. Elmore L W, Sirica A E. Sequential appearance of intestinal mucosal cell types in the right and caudate liver lobes of furan-treated rats. Hepatology 1992; 16:1220-6.
6. Tsukamoto H, Home W, Kamimura S, Niemela O, Parkkila S, Yla-Herttuala S, et. al. Experimental liver cirrhosis induced by alcohol and iron. J Clin Invest 1995; 96:620-30.
7. Miao S, Wang B E, Annoni G, Esposti S D, Biempica L, Zern M A. Two rat models of hepatic fibrosis. A morphologic and molecular comparison. Lab Invest 1990; 63:467-75.
8. Wahl S M, Hunt D A, Allen J B, Wilder R L, Paglia L, Hand A R. Bacterial cell wall-induced hepatic granulomas. An in vivo model of T cell-depen-dent fibrosis. J Exp Med 1986; 163:884-902.
9. O'Neil S, Hunt J, Filkins J, Gamelli R. Obstructive jaundice in rats result in exaggerated hepatic production of tumor necrosis factor-alpha and systemic and tissue tumor necrosis factor-alpha levels after endotoxin. Surgery 1997; 122:281-7.
10. Gerling B, Becker M, Waldschmidt J, Rehmann M, Schupann D. Elevated serum aminoterminal procollagen type-III-peptide parallels collagen accumulation in rats with secondary biliary fibrosis. J Hepatol 1996; 25:79-84.