Reduction of rat cardiac hypertrophy by osthol is related to regulation of cardiac oxidative stress and lipid metabolism

Lipids

Volumn 47, Issue 10, 2012, Pages 987-994

  Zhou, Feng ^a   Zhong, Wen ^a   Xue, Jie ^a   Gu, Zhen Lun ^a   Xie, Mei Lin ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

Cardiac hypertrophy; Hypertension; Lipid metabolism; Osthol; Oxidative stress

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE I; COUMARIN DERIVATIVE; DIACYLGLYCEROL ACYLTRANSFERASE; FATTY ACID; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; MESSENGER RNA; OSTHOLE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CNIDIUM; CNIDIUM MONNIERI; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEEDING; FRUIT; GENE EXPRESSION; HEART MUSCLE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; LIPID METABOLISM; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; RENOVASCULAR HYPERTENSION; TREATMENT DURATION;

ANIMALS; CARDIOMEGALY; CARNITINE O-PALMITOYLTRANSFERASE; CNIDIUM; COUMARINS; DIACYLGLYCEROL O-ACYLTRANSFERASE; GLUTATHIONE PEROXIDASE; LIPID METABOLISM; MALE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUPEROXIDE DISMUTASE;

CNIDIUM MONNIERI; RATTUS;

EID: 84866739122     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-012-3710-1     Document Type: Article

References (32)

1. Purushothaman S, Nair RR, Harikrishnan VS, Fernandez AC (2011) Temporal relation of cardiac hypertrophy, oxidative stress, and fatty acid metabolism in spontaneously hypertensive rat. Mol Cell Biochem 351:59-64
2. Bishop SP, Altschuld RA (1970) Increased glycolytic metabolism in cardiac hypertrophy and congestive failure. Am J Physiol 218:153-159
3. Takeyama D, Kagaya Y, Yamane Y, Shiba N, Chida M, Takahashi T, Ido T, Ishide N, Takishima T (1995) Effects of chronic right ventricular pressure overload on myocardial glucose and free fatty acid metabolism in the conscious rat. Cardiovasc Res 29:763-767
4. Polizio AH, Balestrasse KB, Yannarelli GG, Noriega GO, Gorzalczany S, Taira C, Tomaro ML (2008) Angiotensin II regulates cardiac hypertrophy via oxidative stress but not antioxidant enzyme activities in experimental renovascular hypertension. Hypertens Res 31:325-334
5. Adiga IK, Nair RR (2007) A positive association between cardiomyocyte volume and serum malondialdehyde levels. Int J Cardiol 115:246-248
6. Liu C, Cao F, Tang QZ, Yan L, Dong YG, Zhu LH, Wang L, Bian ZY, Li H (2010) Allicin protects against cardiac hypertrophy and fibrosis via attenuating reactive oxygen species-dependent signaling pathways. J Nutr Biochem 21:1238-1250
7. Bernardo BC, Weeks KL, Pretorius L, McMullen JR (2010) Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies. Pharmacol Therapeut 128:191-227
8. Agrawal R, Agrawal N, Koyani CN, Singh R (2010) Molecular targets and regulators of cardiac hypertrophy. Pharmacol Res 61:269-280
9. Liu JX, Zhang WP, Zhou L, Wang XR, Lian QS (2005) Anti-inflammatory effect and mechanism of osthol in rats. J Chin Med Mater 28:1002-1006
10. Zhang QY, Qin LP, He WD, Van Puyvelde L, Maes D, Adams A, Zheng HC, De Kimpe N (2007) Coumarins from Cnidium monnieri and their antiosteoporotic activity. Planta Med 73:13-19
11. Kuo PL, Hsu YL, Chang CH, Chang JK (2005) Osthole-mediated cell differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway in human osteoblast cells. J Pharmacol Exp Ther 314:1290-1299
12. Liang HJ, Suk FM, Wang CK, Hung LF, Liu DZ, Chen NQ, Chen YC, Chang CC, Liang YC (2009) Osthole, a potential antidiabetic agent, alleviates hyperglycemia in db/db mice. Chem Biol Interact 181:309-315
13. Zhang JJ, Xue J, Wang HB, Zhang Y, Xie ML (2010) Osthole improves alcohol-induced fatty liver in mice by reduction of hepatic oxidative stress. Phytother Res 25:638-643
14. Okamoto T, Kawasaki T, Hino O (2003) Osthole prevents anti-fas antibody-induced hepatitis in mice by affecting the caspase-3-mediated apoptotic pathway. Biochem Pharmacol 65: 677-681
15. Chen R, Xie ML, Zhou J (2005) Experimental study of osthole on inhibition of thrombosis and platelet aggregation. Chin Pharmacol Bull 21:440-443
16. Ogawa H, Sasai N, Kamisako T, Baba K (2007) Effects of osthol on blood pressure and lipid metabolism in stroke-prone spontaneously hypertensive rats. J Ethnopharmacol 112:26-31
17. Chen R, Xue J, Xie ML (2011) Reduction of isoprenaline-induced myocardial TGF-beta1 expression and fibrosis in osthole-treated mice. Toxicol Appl Pharmacol 256:168-173
18. Zhang Y, Xie ML, Xue J, Gu ZL (2007) Osthole improves fat milk-induced fatty liver in rats, modulation of hepatic PPAR-alpha/gamma-mediated lipogenic gene expression. Planta Med 73:718-724
19. Zhang Y, Xie ML, Xue J, Gu ZL (2008) Osthol regulates enzyme protein expression of CYP7A1 and DGAT2 via activation of PPARalpha/gamma in fat milk-induced fatty liver rats. Asian Nat Prod Res 10:807-812
20. Yang QL, Li YH (2007) Roles of PPARs on regulating myocardial energy and lipid homeostasis. J Mol Med 85:697-706
21. Morifuji M, Sanbongi C, Sugiura K (2006) Dietary soya protein intake and exercise training have an additive effect on skeletal muscle fatty acid oxidation enzyme activities and mRNA levels in rat s. Br J Nutr 96:469-475
22. Yen CLE, Stone SJ, Koliwad S, Harris C, Farese RV (2008) DGAT enzymes and triacylglycerol biosynthesis. J Lipid Res 49:2283-2301
23. Sharifi AM, Akbarloo N, Heshmatian B, Ziai A (2003) Alteration of local ACE activity and vascular responsiveness during development of 2K1C renovascular hypertension. Pharmacol Res 47:201-209
24. Okamura T, Miyazaki M, Inagami T, Toda N (1986) Vascular rennin-angiotensin system in two-kidney one clip hypertensive rats. Hypertension 8:560-565
25. Ko FN, Wu TS, Liou MJ, Huang TF, Teng CM (1992) Vasorelaxation of rat thoracic aorta caused by osthole isolated from Angelica pubescens. Eur J Pharmacol 219:29-34
26. Oliveira-Sales EB, Dugaich AP, Carillo BA, Abreu NP, Boim MA, Martins PJ, D'Almeida V, Dolnikoff MS, Bergamaschi CT, Campos RR (2008) Oxidative stress contributes to renovascular hypertension. Am J Hypertens 21:98-104
27. Foussal C, Lairez O, Calise D, Pathak A, Guilbeau-Frugier C, Valet P, Parini A, Kunduzova O (2010) Activation of catalase by apelin prevents oxidative stress-linked cardiac hypertrophy. FEBS Lett 584:2363-2370
28. Jaiswal A, Kumar S, Seth S, Dinda AK, Maulik SK (2010) Effect of U50, 488H, a κ-opioid receptor agonist on myocardial α- and β-myosin heavy chain expression and oxidative stress associated with isoproterenol-induced cardiac hypertrophy in rat. Mol Cell Biochem 345:231-240
29. Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrón M, Chen T, Marcinek DJ, Dorn GW, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS (2011) Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and G alpha q overexpression-induced heart failure. Circ Res 108:837-846
30. Tsujimoto I, Hikoso S, Yamaguchi O, Kashiwase K, Nakai A, Takeda T, Watanabe T, Taniike M, Matsumura Y, Nishida K, Hori M, Kogo M, Otsu K (2005) The antioxidant edaravone attenuates pressure overload-induced left ventricular hypertrophy. Hypertension 45:921-926
31. Sheng R, Gu ZL, Xie ML, Zhou WX, Guo CY (2007) EGCG inhibits cardiomyocyte apoptosis in pressure overload-induced cardiac hypertrophy and protects cardiomyocytes from oxidative stress in rats. Acta Pharmacol Sin 28:191-201
32. Shiota N, Rysa J, Kovanen PT, Rusokaho H, Kokkonen JO, Lindstedt KA (2003) A role for cardiac mast cells in the pathogenesis of hypertensive heart disease. J Hypertens 21:1935-1944