Interferon γ stimulates accumulation of gas phase nitric oxide in differentiated cultures of normal and cystic fibrosis airway epithelial cells

Lung

Volumn 190, Issue 5, 2012, Pages 563-571

  Ostrowski, Lawrence E ^a   Stewart, Daniel ^a   Hazucha, Milan ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Air liquid interface; Airway; Cystic fibrosis; Gas phase; Nitric oxide; Primary ciliary dyskinesia

Indexed keywords

GAMMA INTERFERON; GAS PHASE NITRIC OXIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; UNCLASSIFIED DRUG;

ARTICLE; BRONCHUS; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYSTIC FIBROSIS; EPITHELIUM CELL; GAS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

BRONCHI; CELL DIFFERENTIATION; CELLS, CULTURED; CYSTIC FIBROSIS; EPITHELIAL CELLS; HUMANS; INTERFERON-GAMMA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II;

EID: 84866739044     PISSN: 03412040     EISSN: 14321750     Source Type: Journal    
DOI: 10.1007/s00408-012-9395-7     Document Type: Article

References (32)

1. Ricciardolo FL, Sterk PJ, Gaston B, Folkerts G (2004) Nitric oxide in health and disease of the respiratory system. Physiol Rev 84(3):731-765
2. Zhan X, Li D, Johns RA (2003) Expression of endothelial nitric oxide synthase in ciliated epithelia of rats. J Histochem Cytochem 51(1):81-87
3. Jain B, Rubinstein I, Robbins RA, Leise KL, Sisson JH (1993) Modulation of airway epithelial cell ciliary beat frequency by nitric oxide. Biochem Biophys Res Commun 191(1):83-88
4. Jain B, Rubinstein I, Robbins RA, Sisson JH (1995) TNF-alpha and IL-1 beta upregulate nitric oxide-dependent ciliary motility in bovine airway epithelium. Am J Physiol 268(6 Pt 1):L911-L917
5. Li D, Shirakami G, Zhan X, Johns RA (2000) Regulation of ciliary beat frequency by the nitric oxide-cyclic guanosine monophosphate signaling pathway in rat airway epithelial cells. Am J Respir Cell Mol Biol 23(2):175-181
6. Kharitonov SA, Barnes PJ (2006) Exhaled biomarkers. Chest 130(5):1541-1546
7. Asano K, Chee CB, Gaston B, Lilly CM, Gerard C, Drazen JM, Stamler JS (1994) Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proc Natl Acad Sci USA 91(21):10089-10093
8. Jiang J, Malavia N, Suresh V, George SC (2009) Nitric oxide gas phase release in human small airway epithelial cells. Respir Res 10:3
9. Nathan C, Xie QW (1994) Regulation of biosynthesis of nitric oxide. J Biol Chem 269(19):13725-13728
10. Salkowski CA, Detore G, McNally R, van Rooijen N, Vogel SN (1997) Regulation of inducible nitric oxide synthase messenger RNA expression and nitric oxide production by lipopolysaccharide in vivo: the roles of macrophages, endogenous IFN-gamma, and TNF receptor-1-mediated signaling. J Immunol 158(2):905-912
11. Bush A, Chodhari R, Collins N, Copeland F, Hall P, Harcourt J, Hariri M, Hogg C, Lucas J, Mitchison HM, O'Callaghan C, Phillips G (2007) Primary ciliary dyskinesia: current state of the art. Arch Dis Child 92(12):1136-1140
12. Leigh MW, Pittman JE, Carson JL, Ferkol TW, Dell SD, Davis SD, Knowles MR, Zariwala MA (2009) Clinical and genetic aspects of primary ciliary dyskinesia/Kartagener syndrome. Genet Med 11(7):473-487
13. Lundberg JO, Weitzberg E, Nordvall SL, Kuylenstierna R, Lundberg JM, Alving K (1994) Primarily nasal origin of exhaled nitric oxide and absence in Kartagener's syndrome. Eur Respir J 7(8):1501-1504
14. Noone PG, Leigh MW, Sannuti A, Minnix SL, Carson JL, Hazucha M, Zariwala MA, Knowles MR (2004) Primary ciliary dyskinesia: diagnostic and phenotypic features. Am J Respir Crit Care Med 169(4):459-467
15. Leigh MW, O'Callaghan C, Knowles MR (2011) The challenges of diagnosing primary ciliary dyskinesia. Proc Am Thorac Soc 8(5):434-437
16. Balfour-Lynn IM, Laverty A, Dinwiddie R (1996) Reduced upper airway nitric oxide in cystic fibrosis. Arch Dis Child 75(4): 319-322
17. Grasemann H, Michler E, Wallot M, Ratjen F (1997) Decreased concentration of exhaled nitric oxide (NO) in patients with cystic fibrosis. Pediatr Pulmonol 24(3):173-177
18. Lundberg JO, Nordvall SL, Weitzberg E, Kollberg H, Alving K (1996) Exhaled nitric oxide in paediatric asthma and cystic fibrosis. Arch Dis Child 75(4):323-326
19. Meng QH, Polak JM, Edgar AJ, Chacon MR, Evans TJ, Gruenert DC, Bishop AE (2000) Neutrophils enhance expression of inducible nitric oxide synthase in human normal but not cystic fibrosis bronchial epithelial cells. J Pathol 190(2):126-132
20. Steagall WK, Elmer HL, Brady KG, Kelley TJ (2000) Cystic fibrosis transmembrane conductance regulator-dependent regulation of epithelial inducible nitric oxide synthase expression. Am J Respir Cell Mol Biol 22(1):45-50
21. Kraynack NC, Corey DA, Elmer HL, Kelley TJ (2002) Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 283(3): L604-L611
22. Kreiselmeier NE, Kraynack NC, Corey DA, Kelley TJ (2003) Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol 285(6):L1286-L1295
23. Suresh V, Mih JD, George SC (2007) Measurement of IL-13induced INOS-derived gas phase nitric oxide in human bronchial epithelial cells. Am J Respir Cell Mol Biol 37(1):97-104
24. Fulcher ML, Gabriel S, Burns KA, Yankaskas JR, Randell SH (2005) Well-differentiated human airway epithelial cell cultures. Methods Mol Med 107:183-206
25. Gray TE, Guzman K, Davis CW, Abdullah LH, Nettesheim P (1996) Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells. Am J Respir Cell Mol Biol 14:104-112
26. Thomas SR, Kharitonov SA, Scott SF, Hodson ME, Barnes PJ (2000) Nasal and exhaled nitric oxide is reduced in adult patients with cystic fibrosis and does not correlate with cystic fibrosis genotype. Chest 117(4):1085-1089
27. Barnes PJ, Dweik RA, Gelb AF, Gibson PG, George SC, Grasemann H, Pavord ID, Ratjen F, Silkoff PE, Taylor DR, Zamel N (2010) Exhaled nitric oxide in pulmonary diseases: a comprehensive review. Chest 138(3):682-692
28. Salam MT, Bastain TM, Rappaport EB, Islam T, Berhane K, Gauderman WJ, Gilliland FD (2011) Genetic variations in nitric oxide synthase and arginase Influence exhaled nitric oxide levels in children. Allergy 66(3):412-419
29. Worlitzsch D, Tarran R, Ulrich M, Schwab U, Cekici A, Meyer KC, Birrer P, Bellon G, Berger J, Weiss T, Botzenhart K, Yankaskas JR, Randell S, Boucher RC, Doring G (2002) Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. J Clin Invest 109(3):317-325
30. Haight JS, Qian W, Daya H, Chalmers P, Zamel N (2000) Hypoxia depresses nitric oxide output in the human nasal airways. Laryngoscope 110(3 Pt 1):429-433
31. Nakano H, Ide H, Ogasa T, Osanai S, Imada M, Nonaka S, Kikuchi K, Iwamoto J (2002) Ambient oxygen regulates epithelial metabolism and nitric oxide production in the human nose. J Appl Physiol 93(1):189-194
32. Ide H, Nakano H, Ogasa T, Osanai S, Kikuchi K, Iwamoto J (1999) Regulation of pulmonary circulation by alveolar oxygen tension via airway nitric oxide. J Appl Physiol 87(5):1629-1636