Melatonin down-regulates volume-sensitive chloride channels in fibroblasts

Pflugers Archiv European Journal of Physiology

Volumn 464, Issue 3, 2012, Pages 273-285

  Soussia, Ismail Ben ^a   Mies, Frédérique ^a   Naeije, Robert ^a   Shlyonsky, Vadim ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Anion channel; Cell migration; Cell proliferation; Cell volume; Melatonin receptor; Patch clamp

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CHLORIDE CHANNEL; LUZINDOLE; MELATONIN; MELATONIN 2 RECEPTOR; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG; VOLUME SENSITIVE CHLORIDE CHANNEL;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL SWELLING; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FIBROBLAST; FIBROSIS; HORMONE ACTION; HYPERTENSION; ION CURRENT; LUNG FIBROBLAST; LUNG FIBROSIS; MOUSE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; WHOLE CELL;

ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELL SIZE; CHLORIDE CHANNELS; FIBROBLASTS; INDOLES; MALEIMIDES; MELATONIN; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE C; RATS; RECEPTOR, MELATONIN, MT2; TRYPTAMINES;

EID: 84866733107     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-012-1139-2     Document Type: Article

References (51)

1. Alarma-Estrany P, Crooke A, Mediero A, Peláez T, Pintor J (2008) Sympathetic nervous system modulates the ocular hypotensive action of MT2-melatonin receptors in normotensive rabbits. J Pineal Res 45:468-475
2. Alarma-Estrany P, Guzman-Aranguez A, Huete F, Peral A, Plourde R Jr, Pelaez T, Yerxa B, Pintor J (2011) Design of novel melatonin analogs for the reduction of intraocular pressure in normotensive rabbits. J Pharmacol Exp Ther 337:703-709
3. Anton-Tay F, Ramirez G, Martinez I, Benítez-King G (1998) In vitro stimulation of protein kinase C by melatonin. J Neurochem Res 23:601-606
4. Anwar MM, Meki AR, Rahma HH (2001) Inhibitory effects of melatonin on vascular reactivity: possible role of vasoactive mediators. J Comp Biochem Physiol C Toxicol Pharmacol 130:357-367
5. Bard J, Wright M (1975) The membrane potential of fibroblasts in different environments. J Cell Physiol 84:141-145
6. Benitez-King G (2000) PKC activation by melatonin modulates vimentin intermediate filament organization in N1E-115 cells. J Pineal Res 29:8-14
7. Chilton L, Ohya S, Freed D, George E, Drobic V, Shibukawa Y, Maccannell KA, Imaizumi Y, Clark RB, Dixon IM, Giles WR (2005) K+ currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts. Am J Physiol 288:H2931-H2939
8. Cos S, Fernandez R, Guezmes A, Sánchez-Barceló EJ (1998) Influence of melatonin on invasive and metastatic properties of MCF-7 human breast cancer cells. J Cancer Res 58:4383-4390
9. Crestani B, Besnard V, Boczkowski J (2011) Signalling pathways from NADPH oxidase-4 to idiopathic pulmonary fibrosis. Int J Biochem Cell Biol 43:1086-1089
10. Crutzen R, Shlyonsky V, Louchami K, Virreira M, Hupkens E, Boom A, Sener A, Malaisse WJ, Beauwens R (2012) Does NAD (P)H oxidase-derived H(2)O(2) participate in hypotonicityinduced insulin release by activating VRAC in β-cells? Pflugers Arch 463:377-390
11. Cui P, Yu M, Peng X, Dong L, Yang Z (2011) Melatonin prevents human pancreatic carcinoma cell PANC-1-induced human umbilical vein endothelial cell proliferation and migration by inhibiting vascular endothelial growth factor expression. J Pineal Res 52:236-243
12. Das R, Balonan L, Ballard HJ, Ho S (2008) Chronic hypoxia inhibits the antihypertensive effect of melatonin on pulmonary artery. Int J Cardiol 126:340-345
13. Das M, Dempsey EC, Reeves JT, Stenmark KR (2002) Selective expansion of fibroblast subpopulations from pulmonary artery adventitia in response to hypoxia. Am J Physiol Lung Cell Mol Physiol 282:976-986
14. Ding CN, Cao YX, Zhou L, Zhu DN, Shen ZY, Fei MY, Yu P (2001) Effects of microinjection of melatonin and its receptor antagonists into anterior hypothalamic area on blood pressure and heart rate in rats. J Acta Pharmacol Sin 22:997-1002
15. Gerdin MJ,MasanaMI, Rivera-BermúdezMA, Hudson RL, Earnest DJ, Gillette MU, Dubocovich ML (2004) Melatonin desensitizes endogenous MT2 melatonin receptors in the rat suprachiasmatic nucleus: relevance for defining the periods of sensitivity of the mammalian circadian clock to melatonin. FASEB J 18:1646-1656
16. Girouard H, Chulak C, Lejossec M, Lamontagne D, De Champlain J (2001) Vasorelaxant effects of the chronic treatment with melatonin on mesenteric artery and aorta of spontaneously hypertensive rats. J Hypertens 8:1969-1977
17. Holmes SW, Sugden D (1976) The effect of melatonin on pinealectomy induced hypertension in the rat. Br J Pharmacol 56:360-361
18. Jones TR, Kang IH, Wheeler DB, Lindquist RA, Papallo A, Sabatini DM, Golland P, Carpenter AE (2008) Cell Profiler Analyst: Data exploration and analysis software for complex image-based screens. J BMC Bioinforma 9:482
19. Kim GD, Lee SE, Kim TH, Jin YH, Park YS, Park CS (2011) Melatonin suppresses acrolein-induced IL-8 production in human pulmonary fibroblasts. J Pineal Res. doi:10.1111/j.1600-079X.2011.00950.x
20. King TE Jr, Pardo A, Selman M (2011) Idiopathic pulmonary fibrosis. Lancet 378:1949-1961
21. Lee CH, Yoo KY, Choi JH, Park OK, Hwang IK, Kwon YG, Kim YM, Won MH (2010) Melatonin's protective action against ischemic neuronal damage is associated with up-regulation of the MT2 melatonin receptor. J Neurosci Res 88:2630-2640
22. Li HL, Kang YM, Yu L, Xu HY, Zhao H (2009) Melatonin reduces blood pressure in rats with stress-induced hypertension via GABAA receptors. J Clin Exp Pharmacol Physiol 36:436-440
23. Morrell NW, Adnot S, Archer SL, Dupuis J, Jones PL, MacLean MR, McMurtry IF, Stenmark KR, Thistlethwaite PA, Weissmann N, Yuan JX, Weir EK (2009) Cellular and molecular basis of pulmonary arterial hypertension. J Am Coll Cardiol 54:20-31
24. Nah SS, Won HJ, Park HJ, Ha E, Chung JH, Cho HY, Baik HH (2009) Melatonin inhibits human fibroblast-like synoviocyte proliferation via extracellular signal-regulated protein kinase/ P21CIP1/P27KIP1 pathways. J Pineal Res 47:70-74
25. Nelson PG, Peacock J, Minna J (1972) An active electrical response in fibroblasts. J Gen Physiol 60:58-71
26. Oiki S, Okada Y (1988) Factors responsible for oscillations of membrane potential recorded with tight-seal-patch electrodes in mouse fibroblasts. J Membrane Biol 105:23-32
27. Okada Y, Sato K, Numata T (2009) Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel. J Physiol 587:2141-2149
28. Okatani Y,Watanabe K, Hayashi K,Wakatsuki A, Sagara Y (1997) Melatonin inhibits vasospastic action of hydrogen peroxide in human umbilical artery. J Pineal Res 22:163-168
29. Ortiz-Lopez L, Morales-Mulia S, Ramirez-Rodriguez G, Benítez-King G (2009) ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration. J Pineal Res 46:15-21
30. Paulis L, Pechanova O, Zicha J, Krajcirovicova K, Barta A, Pelouch V, Adamcova M, Simko F (2009) Melatonin prevents fibrosis but not hypertrophy development in the left ventricle of NG-nitro-L-arginine-methyl ester hypertensive rats. J Hypertens Suppl 27:11-16
31. Pitsiou G, Papakosta D, Bouros D (2011) Pulmonary hypertension in idiopathic pulmonary fibrosis: A review. Respiration 82:294-304
32. Sallinen P, Manttari S, Leskinen H, Ilves M, Vakkuri O, Ruskoaho H, Saarela S (2006) The effect of myocardial infarction on the synthesis, concentration and receptor expression of endogenous melatonin. J Pineal Res 42:254-260
33. Schwab A, Nechyporuk-Zloy V, Fabian A, Stock C (2007) Cells move when ions and water flow. Pflugers Arch 453:421-432
34. Shlyonsky V, Ben Soussia I, Naeije R, Mies F (2011) Opposing effects of bone morphogenetic protein-2 and endothelin-1 on lung fibroblast chloride currents. Am J Respir Cell Mol Biol 45:1154-1160
35. Simko F, Paulis L (2007) Melatonin as a potential antihypertensive treatment. J Pineal Res 42:319-322
36. Soto-Vega E, Meza I, Ramirez-Rodriguez G, Benitez-King G (2004) Melatonin stimulates calmodulin phosphorylation by protein kinase C. J Pineal Res 37:98-106
37. Stenmark KR, Bouchey D, Nemenoff R, Dempsey EC, Das M (2000) Hypoxia-induced pulmonary vascular remodeling: Contribution of the adventitial fibroblasts. Physiol Res 49:503-517
38. Stevens T, Phan S, Frid MG, Alvarez D, Herzog E, Stenmark KR (2008) Lung vascular cell heterogeneity: Endothelium, smooth muscle, and fibroblasts. J Proc Am Thorac Soc 15:783-791
39. Swift MR, Todaro GJ (1968) Membrane potentials of human fibroblast strains in culture. J Cell Physiol 71:61-64
40. Tain YL, Huang LT, Lin IC, Lau YT, Lin CY (2010) Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats. J Pineal Res 49:390-398
41. Vaughan MB, Howard EW, Tomasek JJ (2000) Transforming growth factor-beta1 promotes the morphological and functional differentiation of the myofibroblast. J Exp Cell Res 257:180-189
42. Wang GL, Wang XR, Lin MJ, He H, Lan XJ, Guan YY (2002) Deficiency in ClC-3 chloride channels prevents rat aortic smooth muscle cell proliferation. J Circ Res 91:28-32
43. Welsh MG, Cameron IL, Reiter RJ (1979) The pineal gland of the gerbil, Meriones unguiculatus. II. Morphometric analysis over a-hour period. Cell Tissue Res 204:95-109
44. Welsh DJ, Harnett M, Maclean M, Peacock AJ (2004) Proliferation and signaling in fibroblasts: role of 5-hydroxytryptamine2A receptor and transporter. Am J Respir Crit Care Med 170:252-259
45. Xia CM, Shao CH, Xin L, Wang YR, Ding CN, Wang J, Shen LL, Li L, Cao YX, Zhu DN (2008) Effects of melatonin on blood pressure in stress-induced hypertension in rats. J Clin Exp Pharmacol Physiol 35:1258-1264
46. Xiao GN, Guan YY, He H (2002) Effects of Cl-channel blockers on endothelin-1-induced proliferation of rat vascular smooth muscle cells. J Life Sci 70:33-41
47. Yen-Chow YC, Chow SY, Jee WSS, Woodbury DM (1984) Membrane potentials, electrolyte contents, cell pH and some enzyme activities of fibroblasts. In Vitro 20:677-684
48. Yildirim Z, Kotuk M, Erdogan H, Iraz M, Yagmurca M, Kuku I, Fadillioglu E (2006) Preventive effect of melatonin on bleomycininduced lung fibrosis in rats. J Pineal Res 40:27-33
49. Yin Z,Watsky MA (2004) Chloride channel activity in human lung fibroblasts and myofibroblasts. Am J Physiol Lung Cell Mol Physiol 288:1110-1116
50. Zanoboni A, Forni A, Zanoboni-Muciaccia W, Zanussi C (1979) Effect of pinealectomy on arterial blood pressure and food and water intake in the rat. J Endocrinol Investig 2:125-130
51. Zhao WJ, Zhang M, Miao Y, Yang XL, Wang Z (2010) Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells. J Physiol 588:2605-2619