Shaken but unstirred? Effects of micronutrients on stress and trauma after an earthquake: RCT evidence comparing formulas and doses

Human Psychopharmacology

Volumn 27, Issue 5, 2012, Pages 440-454

  Rucklidge, Julia J ^a   Andridge, Rebecca ^b   Gorman, Brigette ^a   Blampied, Neville ^a   Gordon, Heather ^a   Boggis, Anna ^c  

^a UNIVERSITY OF CANTERBURY   (New Zealand)

^b OHIO STATE UNIVERSITY   (United States)

^c West Coast District Health Board   (New Zealand)

Author keywords

disaster; earthquake; micronutrients; stress; trauma; vitamins

Indexed keywords

ASCORBIC ACID PLUS VITAMIN B COMPLEX; CNE; MULTIVITAMIN; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; ADULT; ANXIETY; AROUSAL; ARTICLE; AVOIDANCE BEHAVIOR; CLINICAL GLOBAL IMPRESSION SCALE; CONSTIPATION; CONTROLLED STUDY; DEPRESSION ANXIETY AND STRESS SCALE; DIARRHEA; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; EARTHQUAKE; EMOTION; ENERGY; FEMALE; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; HUMAN EXPERIMENT; IMPACT OF EVENTS SCALE; LOW DRUG DOSE; MALE; MENTAL STRESS; MONITORING; MOOD; NAUSEA; NEW ZEALAND; NORMAL HUMAN; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PERCEIVED STRESS SCALE; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; PSYCHOLOGICAL RATING SCALE; PSYCHOTRAUMA; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SCREENING; SEDATION; SIDE EFFECT; SLEEP DISORDER; THINKING; TRAUMATIC EXPOSURE SEVERITY SCALE; URINE RETENTION; VITAMIN SUPPLEMENTATION; WEIGHT GAIN; XEROSTOMIA;

ADULT; EARTHQUAKES; FEMALE; FENOTEROL; FOLLOW-UP STUDIES; HUMANS; MALE; MICRONUTRIENTS; MIDDLE AGED; MINERALS; NEW ZEALAND; STRESS, PSYCHOLOGICAL; TREATMENT OUTCOME; VITAMINS; YOUNG ADULT;

EID: 84866732181     PISSN: 08856222     EISSN: 10991077     Source Type: Journal    
DOI: 10.1002/hup.2246     Document Type: Article

References (43)

1. Abbasnejad M, Mahani KN, Zamyad A,. 2007. Efficacy of "eye movement desensitization and reprocessing" in reducing anxiety and unpleasant feelings due to earthquake experience. Psychol Res 9: 104-117.
2. Baker CW, Little TD, Brownell KD,. 2003. Predicting adolescent eating and activity behaviors. The role of social norms and personal agency. Health Psychol 22: 189-198.
3. Barringer T, Kirk J, Santaniello A, Foley K, Michielutte R,. 2003. Effect of a multivitamin and mineral supplement on infection and quality of life: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 138: 365-371.
4. Başoǧlu M, Şalcioǧlu E, Livanou M,. 2007. A randomized controlled study of single-session behavioural treatment of earthquake-related post-traumatic stress disorder using an earthquake simulator. Psychol Med: J Res Psychiatry Allied Sci 37: 203-213.
5. Bonanno GA, Brewin CR, Kaniasty K, La Greca AM,. 2010. Weighing the costs of disaster: consequences, risks, and resilience in individuals, families, and communities. Psychol Sci Publ Interest 11: 1-49.
6. Carroll D, Ring C, Suter M, Willemsen G,. 2000. The effects of an oral multivitamin combination with calcium, magnesium, and zinc on psychological well-being in healthy young male volunteers: a double-blind placebo-controlled trial. Psychopharmacology (Berl) 150: 220-225.
7. Chen K, Zhang X, Li T, et al,. 2011. Effect of Vitamin A, vitamin A plus iron and multiple micronutrient-fortified seasoning powder on infectious morbidity of preschool children. Nutrition 27: 428-434.
8. Cohen S, Kamarck T, Mermelstein R,. 1983. A global measure of perceived stress. J Health Soc Behav 24: 385-396.
9. Coulter ID,. 2011. Comparative effectiveness research: does the emperor have clothes? Altern Ther Health Med 17: 8-15.
10. Creamer M, Bell R, Failla S,. 2003. Psychometric properties of the impact of event scale-revised. Behav Res Ther 41: 1489-1496.
11. Diggle P, Heagerty P, Liang KY, Zeger SL,. 2002. Analysis of Longitudinal Data. Claredon Press: Oxford, UK.
12. Elal G, Slade P,. 2005. Traumatic Exposure Severity Scale (TESS): a measure of exposure to major disasters. J Trauma Stress 18: 213-220.
13. Furlan PM, Have TT, Cary M, et al,. 2005. The role of stress-induced cortisol in the relationship between depression and decreased bone mineral density. Biol Psychiatry 57: 911-917.
14. Gariballa S, Forster S,. 2007. Effects of dietary supplements on depressive symptoms in older patients: a randomised double-blind placebo-controlled trial. Clin Nutr 26: 545-551.
15. Gately D, Kaplan BJ,. 2009. Database analysis of adults with bipolar disorder consuming a multinutrient formula. Clin Med Psychiatr 4: 3-16.
16. Gelpin E, Bonne O, Peri T, Brandes D,. 1996. Treatment of recent trauma survivors with benzodiazepines: a prospective study. J Clin Psychiatry 57: 390-394.
17. Glatthaar II,. 1999. Micronutrients and stress. S Afr Med J 89: 16-22.
18. Head KA, Kelly GS,. 2009. Nutrients and botanicals for treatment of stress: adrenal fatigue, neurotransmitter imbalance, anxiety, and restless sleep. Altern Med Rev 14: 114-140.
19. Kang MG, Koh SB, Cha BS, Park JK, Baik SK, Chang JJ,. 2005. Job stress and cardiovascular risk factors in male workers. Prev Med 40: 583-588.
20. Kaplan BJ, Crawford SG, Field CJ, Simpson JS,. 2007. Vitamins, minerals, and mood. Psychol Bull 133: 747-760.
21. Kaplan BJ, Giesbrecht G, Shannon S, McLeod K,. 2011. Evaluating treatments in health care: the instability of a one-legged stool. BMC Med Res Methodol 11.
22. Kemp S, Helton WS, Richardson JJ, Blampied NM, Grimshaw M,. 2011. Sleeplessness, stress, cognitive disruption and academic performance following the September 4, 2010, Christchurch earthquake. Australas J Disast Trauma Stud 2: 11-18.
23. Kennedy DO, Veasey R, Watson A, et al,. 2010. Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males. Psychopharmacology (Berl) 211: 55-68.
24. Kenward MG, Roger JH,. 1997. Small sample inference for fixed effects from restricted maximum likelihood. Biometrics 53: 983-997.
25. Konuk E, Knipe J, Eke I, Yuksek H, Yurtsever A, Ostep S,. 2006. The effects of eye movement desensitization and reprocessing (EMDR) therapy on posttraumatic stress disorder in survivors of the 1999 Marmara, Turkey, earthquake. Int J Stress Manag 13: 291-308.
26. Kuwabara H, Shioiri T, Toyabe S-I, et al,. 2008. Factors impacting on psychological distress and recovery after the 2004 Niigata-Chuetsu earthquake, Japan: community-based study. Psychiatry Clin Neurosci 62: 503-507.
27. Lovibond SH, Lovibond PF,. 1995. Manual for the Depression Anxiety Stress Scales. Psychology Foundation: Sydney.
28. McCann JC, Ames BN,. 2009. Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging? Am J Clin Nutr 90: 889-907.
29. Mehl-Madrona L, Leung B, Kennedy C, Paul S, Kaplan BJ,. 2010. A naturalistic case-control study of micronutrients versus standard medication management in autism. J Child Adolesc Psychopharmacol 20: 95-103.
30. Önder E, Tural Ü, Aker T,. 2006. A comparative study of fluoxetine, moclobemide, and tianeptine in the treatment of posttraumatic stress disorder following an earthquake. Eur Psychiatry 21: 174-179.
31. Rucklidge JJ, Blampied NM,. 2011. Post earthquake functioning in adults with Attention-Deficit/Hyperactivity Disorder: positive effects of micronutrients on resilience. New Zeal J Psychol 40: 51-57.
32. Rucklidge JJ, Johnstone J, Kaplan BJ,. 2009. Nutrient supplementation approaches in the treatment of ADHD. Expert Rev Neurother 9: 461-476.
33. Rucklidge JJ, Johnstone J, Harrison R, Boggis A,. 2011a. Micronutrients reduce stress and anxiety following a 7.1 earthquake in adults with Attention-Deficit/Hyperactivity Disorder. Psychiatry Res 189: 281-287.
34. Rucklidge JJ, Taylor M, Whitehead K,. 2011b. Effect of micronutrients on behavior and mood in adults with ADHD: evidence from an 8-week open label trial with natural extension. J Atten Disord 15: 79-91.
35. Sato Y, Honda Y, Iwamoto J, Kanoko T, Satoh K,. 2005. Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial. JAMA 293: 1082-1088.
36. Sattler DN, De Alvarado AMG, De Castro NB, Van Male R, Zetino AM, Vega R,. 2006. El Salvador earthquakes: relationships among acute stress disorder symptoms, depression, traumatic event exposure, and resource loss. J Trauma Stress 19: 879-893.
37. Schlebusch L, Bosch BA, Polglase G, Kleinschmidt I, Pillay BJ, Cassimjee MH,. 2000. A double-blind, placebo-controlled, double-centre study of the effects of an oral multivitamin-mineral combination on stress. S Afr Med J 90: 1216-1223.
38. Spearing MK, Post RM, Leverich GS, Brandt D, Nolen W,. 1997. Modification of the Clinical Global Impressions (CGI) scale for use with bipolar illness (BP): the CGI: BP. Psychiatry Res 73: 159-171.
39. Stough C, Scholey A, Lloyd J, Spong J, Myers S, Downey LA,. 2011. The effect of 90 day administration of a high dose vitamin B-complex on work stress. Hum Psychopharmacol Clin Exp 26: 470-476.
40. Suhail K, Malik F, Mir IA, Hasan SS, Sarwar A, Tanveer S,. 2009. Psychological health of earthquake survivors in Pakistan. Psychol Develop Soc 21: 183-207.
41. Wang L, Zhang J, Zhou M, Shi Z, Liu P,. 2010. Symptoms of posttraumatic stress disorder among health care workers in earthquake-affected areas in southwest China. Psychol Rep 106: 555-561.
42. Weiss DS, Marmar CR,. 1997. The impact of event scale-revised. In Assessing Psychological Trauma and PTSD: A Practitioner's Handbook, Wilson JP, Keane TM, (eds). Guilford Press: New York; 399-411.
43. Zimmerman M, Martinez JH,. 2012. Web-based assessment of depression in patients treated in clinical practice: reliability, validity, and patient acceptance. J Clin Psychiatry 73: 333-338.