-
1
-
-
55549145072
-
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
-
Epsztejn-Litman S, Feldman N, Abu-Remaileh M, Shufaro Y, Gerson A, Ueda J et al. De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes. Nat Struct Mol Biol 2008; 15: 1176-1183.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1176-1183
-
-
Epsztejn-Litman, S.1
Feldman, N.2
Abu-Remaileh, M.3
Shufaro, Y.4
Gerson, A.5
Ueda, J.6
-
2
-
-
54349114603
-
DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity
-
Dong KB, Maksakova IA, Mohn F, Leung D, Appanah R, Lee S et al. DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity. EMBO J 2008; 27: 2691-2701.
-
(2008)
EMBO J
, vol.27
, pp. 2691-2701
-
-
Dong, K.B.1
Maksakova, I.A.2
Mohn, F.3
Leung, D.4
Appanah, R.5
Lee, S.6
-
3
-
-
14844345317
-
Transcription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene
-
Nguyen TT, Cho K, Stratton SA, Barton MC. Transcription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene. Mol Cell Biol 2005; 25: 2147-2157.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2147-2157
-
-
Nguyen, T.T.1
Cho, K.2
Stratton, S.A.3
Barton, M.C.4
-
4
-
-
57749094930
-
G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance
-
El Gazzar M, Yoza BK, Chen X, Hu J, Hawkins GA, McCall CE. G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance. J Biol Chem 2008; 283: 32198-32208.
-
(2008)
J Biol Chem
, vol.283
, pp. 32198-32208
-
-
El Gazzar, M.1
Yoza, B.K.2
Chen, X.3
Hu, J.4
Hawkins, G.A.5
McCall, C.E.6
-
5
-
-
0037099413
-
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis
-
Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M et al. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev 2002; 16: 1779-1791.
-
(2002)
Genes Dev
, vol.16
, pp. 1779-1791
-
-
Tachibana, M.1
Sugimoto, K.2
Nozaki, M.3
Ueda, J.4
Ohta, T.5
Ohki, M.6
-
6
-
-
77953069207
-
Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B
-
Jiang Y, Jakovcevski M, Bharadwaj R, Connor C, Schroeder FA, Lin CL et al. Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B. J Neurosci 2010; 30: 7152-7167.
-
(2010)
J Neurosci
, vol.30
, pp. 7152-7167
-
-
Jiang, Y.1
Jakovcevski, M.2
Bharadwaj, R.3
Connor, C.4
Schroeder, F.A.5
Lin, C.L.6
-
7
-
-
59149083658
-
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells
-
Wen B, Wu H, Shinkai Y, Irizarry RA, Feinberg AP. Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells. Nat Genet 2009; 41: 246-250.
-
(2009)
Nat Genet
, vol.41
, pp. 246-250
-
-
Wen, B.1
Wu, H.2
Shinkai, Y.3
Irizarry, R.A.4
Feinberg, A.P.5
-
8
-
-
79955460159
-
H3K9 methyltransferase G9a and the related molecule GLP
-
Shinkai Y, Tachibana M. H3K9 methyltransferase G9a and the related molecule GLP. Genes Dev 2011; 25: 781-788.
-
(2011)
Genes Dev
, vol.25
, pp. 781-788
-
-
Shinkai, Y.1
Tachibana, M.2
-
9
-
-
0015296118
-
The distribution and turnover of labeled methyl groups in histone fractions of cultured mammalian cells
-
Byvoet P, Shepherd GR, Hardin JM, Noland BJ. The distribution and turnover of labeled methyl groups in histone fractions of cultured mammalian cells. Arch Biochem Biophys 1972; 148: 558-567.
-
(1972)
Arch Biochem Biophys
, vol.148
, pp. 558-567
-
-
Byvoet, P.1
Shepherd, G.R.2
Hardin, J.M.3
Noland, B.J.4
-
10
-
-
78649698079
-
Global turnover of histone post-translational modifications and variants in human cells
-
Zee BM, Levin RS, Dimaggio PA, Garcia BA. Global turnover of histone post-translational modifications and variants in human cells. Epigenetics Chromatin 2010; 3: 22.
-
(2010)
Epigenetics Chromatin
, vol.3
, pp. 22
-
-
Zee, B.M.1
Levin, R.S.2
Dimaggio, P.A.3
Garcia, B.A.4
-
11
-
-
0016835983
-
Studies on highly metabolically active acetylation and phosphorylation of histones
-
Jackson V, Shires A, Chalkley R, Granner DK. Studies on highly metabolically active acetylation and phosphorylation of histones. J Biol Chem 1975; 250: 4856-4863.
-
(1975)
J Biol Chem
, vol.250
, pp. 4856-4863
-
-
Jackson, V.1
Shires, A.2
Chalkley, R.3
Granner, D.K.4
-
12
-
-
29144463657
-
Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: Analysis at c-fos and cjun
-
Hazzalin CA, Mahadevan LC. Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: Analysis at c-fos and cjun. PLoS Biol 2005; 3: e393.
-
(2005)
PLoS Biol
, vol.3
-
-
Hazzalin, C.A.1
Mahadevan, L.C.2
-
13
-
-
9244234323
-
Schizophrenia, epigenetics and ligand-activated nuclear receptors: A framework for chromatin therapeutics
-
Sharma RP. Schizophrenia, epigenetics and ligand-activated nuclear receptors: A framework for chromatin therapeutics. Schizophr Res 2005; 72: 79-90.
-
(2005)
Schizophr Res
, vol.72
, pp. 79-90
-
-
Sharma, R.P.1
-
14
-
-
35348856827
-
Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells
-
Dai B, Rasmussen TP. Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells. Stem Cells 2007; 25: 2567-2574.
-
(2007)
Stem Cells
, vol.25
, pp. 2567-2574
-
-
Dai, B.1
Rasmussen, T.P.2
-
15
-
-
77954359979
-
A case study in cross-talk: The histone lysine methyltransferases G9a and GLP
-
Collins R, Cheng X. A case study in cross-talk: The histone lysine methyltransferases G9a and GLP. Nucleic Acids Res 2010; 38: 3503-3511.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 3503-3511
-
-
Collins, R.1
Cheng, X.2
-
16
-
-
0031214069
-
Nuclear matrix, dynamic histone acetylation and transcriptionally active chromatin
-
Davie JR. Nuclear matrix, dynamic histone acetylation and transcriptionally active chromatin. Mol Biol Rep 1997; 24: 197-207.
-
(1997)
Mol Biol Rep
, vol.24
, pp. 197-207
-
-
Davie, J.R.1
-
17
-
-
0037087576
-
Dynamics of global histone acetylation and deacetylation in vivo: Rapid restoration of normal histone acetylation status upon removal of activators and repressors
-
Katan-Khaykovich Y, Struhl K. Dynamics of global histone acetylation and deacetylation in vivo: Rapid restoration of normal histone acetylation status upon removal of activators and repressors. Genes Dev 2002; 16: 743-752.
-
(2002)
Genes Dev
, vol.16
, pp. 743-752
-
-
Katan-Khaykovich, Y.1
Struhl, K.2
-
18
-
-
13944262010
-
Epigenetic ontogeny of the igk locus during B cell development
-
Goldmit M, Ji Y, Skok J, Roldan E, Jung S, Cedar H et al. Epigenetic ontogeny of the igk locus during B cell development. Nat Immunol 2005; 6: 198-203.
-
(2005)
Nat Immunol
, vol.6
, pp. 198-203
-
-
Goldmit, M.1
Ji, Y.2
Skok, J.3
Roldan, E.4
Jung, S.5
Cedar, H.6
-
19
-
-
33644850958
-
Heterochromatin protein 1: Don't judge the book by its cover!
-
Hediger F, Gasser SM. Heterochromatin protein 1: Don't judge the book by its cover!. Curr Opin Genet Dev 2006; 16: 143-150.
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 143-150
-
-
Hediger, F.1
Gasser, S.M.2
-
20
-
-
0037086355
-
Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail
-
Jacobs SA, Khorasanizadeh S. Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail. Science 2002; 295: 2080-2083.
-
(2002)
Science
, vol.295
, pp. 2080-2083
-
-
Jacobs, S.A.1
Khorasanizadeh, S.2
-
21
-
-
0034599522
-
The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer
-
Brasher SV, Smith BO, Fogh RH, Nietlispach D, Thiru A, Nielsen PR et al. The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer. EMBO J 2000; 19: 1587-1597.
-
(2000)
EMBO J
, vol.19
, pp. 1587-1597
-
-
Brasher, S.V.1
Smith, B.O.2
Fogh, R.H.3
Nietlispach, D.4
Thiru, A.5
Nielsen, P.R.6
-
22
-
-
45149084413
-
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
-
Guelen L, Pagie L, Brasset E, Meuleman W, Faza MB, Talhout W et al. Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. Nature 2008; 453: 948-951.
-
(2008)
Nature
, vol.453
, pp. 948-951
-
-
Guelen, L.1
Pagie, L.2
Brasset, E.3
Meuleman, W.4
Faza, M.B.5
Talhout, W.6
-
23
-
-
0041624239
-
Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: A mammalian cell culture model of gene variegation
-
Ayyanathan K, Lechner MS, Bell P, Maul GG, Schultz DC, Yamada Y et al. Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: A mammalian cell culture model of gene variegation. Genes Dev 2003; 17: 1855-1869.
-
(2003)
Genes Dev
, vol.17
, pp. 1855-1869
-
-
Ayyanathan, K.1
Lechner, M.S.2
Bell, P.3
Maul, G.G.4
Schultz, D.C.5
Yamada, Y.6
-
24
-
-
0346525136
-
Modulation of heterochromatin protein 1 dynamics in primary mammalian cells
-
Festenstein R, Pagakis SN, Hiragami K, Lyon D, Verreault A, Sekkali B et al. Modulation of heterochromatin protein 1 dynamics in primary mammalian cells. Science 2003; 299: 719-721.
-
(2003)
Science
, vol.299
, pp. 719-721
-
-
Festenstein, R.1
Pagakis, S.N.2
Hiragami, K.3
Lyon, D.4
Verreault, A.5
Sekkali, B.6
-
25
-
-
20144370936
-
Dissociation of heterochromatin protein 1 from lamin B receptor induced by human polyomavirus agnoprotein: Role in nuclear egress of viral particles
-
Okada Y, Suzuki T, Sunden Y, Orba Y, Kose S, Imamoto N et al. Dissociation of heterochromatin protein 1 from lamin B receptor induced by human polyomavirus agnoprotein: Role in nuclear egress of viral particles. EMBO Rep 2005; 6: 452-457.
-
(2005)
EMBO Rep
, vol.6
, pp. 452-457
-
-
Okada, Y.1
Suzuki, T.2
Sunden, Y.3
Orba, Y.4
Kose, S.5
Imamoto, N.6
-
26
-
-
77954818442
-
Genome-nuclear lamina interactions and gene regulation
-
Kind J, van Steensel B. Genome-nuclear lamina interactions and gene regulation. Curr Opin Cell Biol 2010; 22: 320-325.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 320-325
-
-
Kind, J.1
Van Steensel, B.2
-
27
-
-
18044364584
-
Cell-by-cell dissection of gene expression and chromosomal interactions reveals consequences of nuclear reorganization
-
Harmon B, Sedat J. Cell-by-cell dissection of gene expression and chromosomal interactions reveals consequences of nuclear reorganization. PLoS Biol 2005; 3: e67.
-
(2005)
PLoS Biol
, vol.3
-
-
Harmon, B.1
Sedat, J.2
-
28
-
-
33845755946
-
Heterochromatin revisited
-
Grewal SI, Jia S. Heterochromatin revisited. Nat Rev Genet 2007; 8: 35-46.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 35-46
-
-
Grewal, S.I.1
Jia, S.2
-
29
-
-
77952576224
-
Molecular maps of the reorganization of genomenuclear lamina interactions during differentiation
-
Peric-Hupkes D, Meuleman W, Pagie L, Bruggeman SW, Solovei I, Brugman W et al. Molecular maps of the reorganization of genomenuclear lamina interactions during differentiation. Mol Cell 2010; 38: 603-613.
-
(2010)
Mol Cell
, vol.38
, pp. 603-613
-
-
Peric-Hupkes, D.1
Meuleman, W.2
Pagie, L.3
Bruggeman, S.W.4
Solovei, I.5
Brugman, W.6
-
30
-
-
20244375017
-
Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes
-
Baxter J, Sauer S, Peters A, John R, Williams R, Caparros ML et al. Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes. EMBO J 2004; 23: 4462-4472.
-
(2004)
EMBO J
, vol.23
, pp. 4462-4472
-
-
Baxter, J.1
Sauer, S.2
Peters, A.3
John, R.4
Williams, R.5
Caparros, M.L.6
-
31
-
-
67749120074
-
Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures
-
Gavin DP, Rosen C, Chase K, Grayson DR, Tun N, Sharma RP. Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. J Psychiatry Neurosci 2009; 34: 232-237.
-
(2009)
J Psychiatry Neurosci
, vol.34
, pp. 232-237
-
-
Gavin, D.P.1
Rosen, C.2
Chase, K.3
Grayson, D.R.4
Tun, N.5
Sharma, R.P.6
-
32
-
-
33750626746
-
Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: Preliminary results from a clinical population
-
Sharma RP, Rosen C, Kartan S, Guidotti A, Costa E, Grayson DR et al. Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: Preliminary results from a clinical population. Schizophr Res 2006; 88: 227-231.
-
(2006)
Schizophr Res
, vol.88
, pp. 227-231
-
-
Sharma, R.P.1
Rosen, C.2
Kartan, S.3
Guidotti, A.4
Costa, E.5
Grayson, D.R.6
-
33
-
-
79952582606
-
Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens
-
Maze I, Feng J, Wilkinson MB, Sun H, Shen L, Nestler EJ. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proc Natl Acad Sci USA 2011; 108: 3035-3040.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3035-3040
-
-
Maze, I.1
Feng, J.2
Wilkinson, M.B.3
Sun, H.4
Shen, L.5
Nestler, E.J.6
-
34
-
-
71149121303
-
Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex
-
Schaefer A, Sampath SC, Intrator A, Min A, Gertler TS, Surmeier DJ et al. Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. Neuron 2009; 64: 678-691.
-
(2009)
Neuron
, vol.64
, pp. 678-691
-
-
Schaefer, A.1
Sampath, S.C.2
Intrator, A.3
Min, A.4
Gertler, T.S.5
Surmeier, D.J.6
-
35
-
-
44349103591
-
A combined chemical and genetic approach for the generation of induced pluripotent stem cells
-
Shi Y, Do JT, Desponts C, Hahm HS, Scholer HR, Ding S. A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2008; 2: 525-528.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 525-528
-
-
Shi, Y.1
Do, J.T.2
Desponts, C.3
Hahm, H.S.4
Scholer, H.R.5
Ding, S.6
-
36
-
-
74249105659
-
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
-
Maze I, Covington HE, Dietz DM, LaPlant Q, Renthal W, Russo SJ et al. Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science 2010; 327: 213-216.
-
(2010)
Science
, vol.327
, pp. 213-216
-
-
Maze, I.1
Covington, H.E.2
Dietz, D.M.3
Laplant, Q.4
Renthal, W.5
Russo, S.J.6
-
37
-
-
0035134393
-
FosB in rat striatum: Normal regional distribution and enhanced expression after 6-month haloperidol administration
-
Rodriguez JJ, Garcia DR, Nakabeppu Y, Pickel VM. FosB in rat striatum: Normal regional distribution and enhanced expression after 6-month haloperidol administration. Synapse 2001; 39: 122-132.
-
(2001)
Synapse
, vol.39
, pp. 122-132
-
-
Rodriguez, J.J.1
Garcia, D.R.2
Nakabeppu, Y.3
Pickel, V.M.4
-
38
-
-
77949357100
-
Histone methylation regulates memory formation
-
Gupta S, Kim SY, Artis S, Molfese DL, Schumacher A, Sweatt JD et al. Histone methylation regulates memory formation. J Neurosci 2010; 30: 3589-3599.
-
(2010)
J Neurosci
, vol.30
, pp. 3589-3599
-
-
Gupta, S.1
Kim, S.Y.2
Artis, S.3
Molfese, D.L.4
Schumacher, A.5
Sweatt, J.D.6
-
39
-
-
33645357786
-
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action
-
Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 2006; 9: 519-525.
-
(2006)
Nat Neurosci
, vol.9
, pp. 519-525
-
-
Tsankova, N.M.1
Berton, O.2
Renthal, W.3
Kumar, A.4
Neve, R.L.5
Nestler, E.J.6
-
40
-
-
62049083789
-
Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294
-
Chang Y, Zhang X, Horton JR, Upadhyay AK, Spannhoff A, Liu J et al. Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294. Nat Struct Mol Biol 2009; 16: 312-317.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 312-317
-
-
Chang, Y.1
Zhang, X.2
Horton, J.R.3
Upadhyay, A.K.4
Spannhoff, A.5
Liu, J.6
-
41
-
-
33645132331
-
G9amediated irreversible epigenetic inactivation of oct-3/4 during early embryogenesis
-
Feldman N, Gerson A, Fang J, Li E, Zhang Y, Shinkai Y et al. G9amediated irreversible epigenetic inactivation of oct-3/4 during early embryogenesis. Nat Cell Biol 2006; 8: 188-194.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 188-194
-
-
Feldman, N.1
Gerson, A.2
Fang, J.3
Li, E.4
Zhang, Y.5
Shinkai, Y.6
-
42
-
-
77955363182
-
Protein lysine methyltransferase G9a inhibitors: Design, syn thesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines
-
Liu F, Chen X, Allali-Hassani A, Quinn AM, Wigle TJ, Wasney GA et al. Protein lysine methyltransferase G9a inhibitors: Design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines. J Med Chem 2010; 53: 5844-5857.
-
(2010)
J Med Chem
, vol.53
, pp. 5844-5857
-
-
Liu, F.1
Chen, X.2
Allali-Hassani, A.3
Quinn, A.M.4
Wigle, T.J.5
Wasney, G.A.6
-
43
-
-
33846690407
-
Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors
-
Garcia-Bassets I, Kwon YS, Telese F, Prefontaine GG, Hutt KR, Cheng CS et al. Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell 2007; 128: 505-518.
-
(2007)
Cell
, vol.128
, pp. 505-518
-
-
Garcia-Bassets, I.1
Kwon, Y.S.2
Telese, F.3
Prefontaine, G.G.4
Hutt, K.R.5
Cheng, C.S.6
-
44
-
-
70349335528
-
Mechanisms of transcriptional repression by histone lysine methylation
-
Hublitz P, Albert M, Peters AH. Mechanisms of transcriptional repression by histone lysine methylation. Int J Dev Biol 2009; 53: 335-354.
-
(2009)
Int J Dev Biol
, vol.53
, pp. 335-354
-
-
Hublitz, P.1
Albert, M.2
Peters, A.H.3
-
45
-
-
0035282458
-
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
-
Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC et al. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 2001; 410: 120-124.
-
(2001)
Nature
, vol.410
, pp. 120-124
-
-
Bannister, A.J.1
Zegerman, P.2
Partridge, J.F.3
Miska, E.A.4
Thomas, J.O.5
Allshire, R.C.6
-
47
-
-
0242348752
-
Histone lysine methylation: A signature for chromatin function
-
Sims III RJ, Nishioka K, Reinberg D. Histone lysine methylation: A signature for chromatin function. Trends Genet 2003; 19: 629-639.
-
(2003)
Trends Genet
, vol.19
, pp. 629-639
-
-
Sims Iii., R.J.1
Nishioka, K.2
Reinberg, D.3
|