Synthesis and anti-cancer efficacy of rapid hydrolysed water-soluble paclitaxel pro-drugs

Journal of Biomaterials Science, Polymer Edition

Volumn 19, Issue 3, 2008, Pages 311-324

  Ryu, Beom Young ^a   Sohn, Jeong Sun ^a   Hess, Michael ^b   Choi, Soo Kyung ^a   Choi, Jae Kon ^a   Jo, Byung Wook ^a  

^a Chosun University   (South Korea)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Anti cancer efficiacy; Paclitaxel; Pro drug; Self immolating linker; Synthesis

Indexed keywords

CELL GROWTH; DRUG PRODUCTS; ENZYME ACTIVITY; ENZYME INHIBITION; HYDROLYSIS; TUMORS;

ANTI-CANCER EFFICIACY; PACLITAXEL; PRO-DRUG; SELF-IMMOLATING LINKERS;

ONCOLOGY;

PACLITAXEL; PEGYLATED PACLITAXEL; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LUNG METASTASIS; MALE; MELANOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR XENOGRAFT;

MURINAE; MUS; RATTUS;

EID: 39749111804     PISSN: 09205063     EISSN: 15685624     Source Type: Journal    
DOI: 10.1163/156856208783720994     Document Type: Article

References (38)