-
1
-
-
0026695259
-
tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors
-
Dumont DJ, Yamaguchi TP, Conlon RA, Rossant J, Breitman ML, (1992) tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors. Oncogene 7: 1471-1480.
-
(1992)
Oncogene
, vol.7
, pp. 1471-1480
-
-
Dumont, D.J.1
Yamaguchi, T.P.2
Conlon, R.A.3
Rossant, J.4
Breitman, M.L.5
-
2
-
-
0029001244
-
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
-
Sato TN, Tozawa Y, Deutsch U, Wolburg-Buchholz K, Fujiwara Y, et al. (1995) Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 376: 70-74.
-
(1995)
Nature
, vol.376
, pp. 70-74
-
-
Sato, T.N.1
Tozawa, Y.2
Deutsch, U.3
Wolburg-Buchholz, K.4
Fujiwara, Y.5
-
3
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
-
Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, et al. (1996) Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87: 1171-1180.
-
(1996)
Cell
, vol.87
, pp. 1171-1180
-
-
Suri, C.1
Jones, P.F.2
Patan, S.3
Bartunkova, S.4
Maisonpierre, P.C.5
-
4
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, et al. (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380: 435-439.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
-
5
-
-
0033601357
-
Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1
-
Thurston G, Suri C, Smith K, McClain J, Sato TN, et al. (1999) Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 286: 2511-2514.
-
(1999)
Science
, vol.286
, pp. 2511-2514
-
-
Thurston, G.1
Suri, C.2
Smith, K.3
McClain, J.4
Sato, T.N.5
-
6
-
-
0034036689
-
Angiopoietin-1 protects the adult vasculature against plasma leakage
-
Thurston G, Rudge JS, Ioffe E, Zhou H, Ross L, et al. (2000) Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med 6: 460-463.
-
(2000)
Nat Med
, vol.6
, pp. 460-463
-
-
Thurston, G.1
Rudge, J.S.2
Ioffe, E.3
Zhou, H.4
Ross, L.5
-
7
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, et al. (2000) Vascular-specific growth factors and blood vessel formation. Nature 407: 242-248.
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
Rudge, J.S.4
Wiegand, S.J.5
-
8
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, et al. (1997) Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277: 55-60.
-
(1997)
Science
, vol.277
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
-
9
-
-
0032939205
-
Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma
-
Tanaka S, Mori M, Sakamoto Y, Makuuchi M, Sugimachi K, et al. (1999) Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma. J Clin Invest 103: 341-345.
-
(1999)
J Clin Invest
, vol.103
, pp. 341-345
-
-
Tanaka, S.1
Mori, M.2
Sakamoto, Y.3
Makuuchi, M.4
Sugimachi, K.5
-
10
-
-
0032504757
-
Vascular endothelial growth factor and the angiopoietins: working together to build a better blood vessel
-
Peters KG, (1998) Vascular endothelial growth factor and the angiopoietins: working together to build a better blood vessel. Circ Res 83: 342-343.
-
(1998)
Circ Res
, vol.83
, pp. 342-343
-
-
Peters, K.G.1
-
11
-
-
0037143737
-
Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo
-
Lobov IB, Brooks PC, Lang RA, (2002) Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci U S A 99: 11205-11210.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11205-11210
-
-
Lobov, I.B.1
Brooks, P.C.2
Lang, R.A.3
-
12
-
-
0031729982
-
Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis
-
Goede V, Schmidt T, Kimmina S, Kozian D, Augustin HG, (1998) Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis. Lab Invest 78: 1385-1394.
-
(1998)
Lab Invest
, vol.78
, pp. 1385-1394
-
-
Goede, V.1
Schmidt, T.2
Kimmina, S.3
Kozian, D.4
Augustin, H.G.5
-
13
-
-
0034648666
-
Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway
-
Kim I, Kim JH, Moon SO, Kwak HJ, Kim NG, et al. (2000) Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Oncogene 19: 4549-4552.
-
(2000)
Oncogene
, vol.19
, pp. 4549-4552
-
-
Kim, I.1
Kim, J.H.2
Moon, S.O.3
Kwak, H.J.4
Kim, N.G.5
-
14
-
-
0035895712
-
Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2
-
Teichert-Kuliszewska K, Maisonpierre PC, Jones N, Campbell AI, Master Z, et al. (2001) Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2. Cardiovasc Res 49: 659-670.
-
(2001)
Cardiovasc Res
, vol.49
, pp. 659-670
-
-
Teichert-Kuliszewska, K.1
Maisonpierre, P.C.2
Jones, N.3
Campbell, A.I.4
Master, Z.5
-
15
-
-
0032504752
-
Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization
-
Asahara T, Chen D, Takahashi T, Fujikawa K, Kearney M, et al. (1998) Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. Circ Res 83: 233-240.
-
(1998)
Circ Res
, vol.83
, pp. 233-240
-
-
Asahara, T.1
Chen, D.2
Takahashi, T.3
Fujikawa, K.4
Kearney, M.5
-
16
-
-
0032506290
-
Direct intramuscular injection of plasmid DNA encoding angiopoietin-1 but not angiopoietin-2 augments revascularization in the rabbit ischemic hindlimb
-
Shyu KG, Manor O, Magner M, Yancopoulos GD, Isner JM, (1998) Direct intramuscular injection of plasmid DNA encoding angiopoietin-1 but not angiopoietin-2 augments revascularization in the rabbit ischemic hindlimb. Circulation 98: 2081-2087.
-
(1998)
Circulation
, vol.98
, pp. 2081-2087
-
-
Shyu, K.G.1
Manor, O.2
Magner, M.3
Yancopoulos, G.D.4
Isner, J.M.5
-
17
-
-
34447643563
-
Angiopoietin-2 impairs revascularization after limb ischemia
-
Reiss Y, Droste J, Heil M, Tribulova S, Schmidt MH, et al. (2007) Angiopoietin-2 impairs revascularization after limb ischemia. Circ Res 101: 88-96.
-
(2007)
Circ Res
, vol.101
, pp. 88-96
-
-
Reiss, Y.1
Droste, J.2
Heil, M.3
Tribulova, S.4
Schmidt, M.H.5
-
18
-
-
0033882191
-
Angiopoietin 2 expression in the retina: upregulation during physiologic and pathologic neovascularization
-
Hackett SF, Ozaki H, Strauss RW, Wahlin K, Suri C, et al. (2000) Angiopoietin 2 expression in the retina: upregulation during physiologic and pathologic neovascularization. J Cell Physiol 184: 275-284.
-
(2000)
J Cell Physiol
, vol.184
, pp. 275-284
-
-
Hackett, S.F.1
Ozaki, H.2
Strauss, R.W.3
Wahlin, K.4
Suri, C.5
-
19
-
-
18644382318
-
Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1
-
Gale NW, Thurston G, Hackett SF, Renard R, Wang Q, et al. (2002) Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1. Dev Cell 3: 411-423.
-
(2002)
Dev Cell
, vol.3
, pp. 411-423
-
-
Gale, N.W.1
Thurston, G.2
Hackett, S.F.3
Renard, R.4
Wang, Q.5
-
20
-
-
55449131657
-
Angiopoietin-2 stimulates blood flow recovery after femoral artery occlusion by inducing inflammation and arteriogenesis
-
Tressel SL, Kim H, Ni CW, Chang K, Velasquez-Castano JC, et al. (2008) Angiopoietin-2 stimulates blood flow recovery after femoral artery occlusion by inducing inflammation and arteriogenesis. Arterioscler Thromb Vasc Biol 28: 1989-1995.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1989-1995
-
-
Tressel, S.L.1
Kim, H.2
Ni, C.W.3
Chang, K.4
Velasquez-Castano, J.C.5
-
21
-
-
0038108603
-
Impaired arteriogenic response to acute hindlimb ischemia in CD4-knockout mice
-
Stabile E, Burnett MS, Watkins C, Kinnaird T, Bachis A, et al. (2003) Impaired arteriogenic response to acute hindlimb ischemia in CD4-knockout mice. Circulation 108: 205-210.
-
(2003)
Circulation
, vol.108
, pp. 205-210
-
-
Stabile, E.1
Burnett, M.S.2
Watkins, C.3
Kinnaird, T.4
Bachis, A.5
-
22
-
-
0030928783
-
Recommended standards for reports dealing with lower extremity ischemia: revised version
-
Rutherford RB, Baker JD, Ernst C, Johnston KW, Porter JM, et al. (1997) Recommended standards for reports dealing with lower extremity ischemia: revised version. J Vasc Surg 26: 517-538.
-
(1997)
J Vasc Surg
, vol.26
, pp. 517-538
-
-
Rutherford, R.B.1
Baker, J.D.2
Ernst, C.3
Johnston, K.W.4
Porter, J.M.5
-
23
-
-
0037689525
-
Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors
-
Arsic N, Zentilin L, Zacchigna S, Santoro D, Stanta G, et al. (2003) Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors. Mol Ther 7: 450-459.
-
(2003)
Mol Ther
, vol.7
, pp. 450-459
-
-
Arsic, N.1
Zentilin, L.2
Zacchigna, S.3
Santoro, D.4
Stanta, G.5
-
24
-
-
0037062491
-
Orchestration of angiogenesis and arteriovenous contribution by angiopoietins and vascular endothelial growth factor (VEGF)
-
Visconti RP, Richardson CD, Sato TN, (2002) Orchestration of angiogenesis and arteriovenous contribution by angiopoietins and vascular endothelial growth factor (VEGF). Proc Natl Acad Sci U S A 99: 8219-8224.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8219-8224
-
-
Visconti, R.P.1
Richardson, C.D.2
Sato, T.N.3
-
25
-
-
0142222482
-
Pre-administration of angiopoietin-1 followed by VEGF induces functional and mature vascular formation in a rabbit ischemic model
-
Yamauchi A, Ito Y, Morikawa M, Kobune M, Huang J, et al. (2003) Pre-administration of angiopoietin-1 followed by VEGF induces functional and mature vascular formation in a rabbit ischemic model. J Gene Med 5: 994-1004.
-
(2003)
J Gene Med
, vol.5
, pp. 994-1004
-
-
Yamauchi, A.1
Ito, Y.2
Morikawa, M.3
Kobune, M.4
Huang, J.5
-
26
-
-
33751225092
-
Angiopoietins: a link between angiogenesis and inflammation
-
Fiedler U, Augustin HG, (2006) Angiopoietins: a link between angiogenesis and inflammation. Trends Immunol 27: 552-558.
-
(2006)
Trends Immunol
, vol.27
, pp. 552-558
-
-
Fiedler, U.1
Augustin, H.G.2
-
27
-
-
32244436305
-
Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation
-
Fiedler U, Reiss Y, Scharpfenecker M, Grunow V, Koidl S, et al. (2006) Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation. Nat Med 12: 235-239.
-
(2006)
Nat Med
, vol.12
, pp. 235-239
-
-
Fiedler, U.1
Reiss, Y.2
Scharpfenecker, M.3
Grunow, V.4
Koidl, S.5
-
28
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff JA, Malone RW, Williams P, Chong W, Acsadi G, et al. (1990) Direct gene transfer into mouse muscle in vivo. Science 247: 1465-1468.
-
(1990)
Science
, vol.247
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
Chong, W.4
Acsadi, G.5
-
29
-
-
0029744337
-
Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector
-
Tripathy SK, Svensson EC, Black HB, Goldwasser E, Margalith M, et al. (1996) Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector. Proc Natl Acad Sci U S A 93: 10876-10880.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10876-10880
-
-
Tripathy, S.K.1
Svensson, E.C.2
Black, H.B.3
Goldwasser, E.4
Margalith, M.5
-
30
-
-
19044389402
-
Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of end-stage unreconstructible lower extremity ischemia: preliminary results of a phase I trial
-
Comerota AJ, Throm RC, Miller KA, Henry T, Chronos N, et al. (2002) Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of end-stage unreconstructible lower extremity ischemia: preliminary results of a phase I trial. J Vasc Surg 35: 930-936.
-
(2002)
J Vasc Surg
, vol.35
, pp. 930-936
-
-
Comerota, A.J.1
Throm, R.C.2
Miller, K.A.3
Henry, T.4
Chronos, N.5
-
31
-
-
77958042477
-
Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody
-
Coxon A, Bready J, Min H, Kaufman S, Leal J, et al. (2010) Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody. Mol Cancer Ther 9: 2641-2651.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 2641-2651
-
-
Coxon, A.1
Bready, J.2
Min, H.3
Kaufman, S.4
Leal, J.5
-
32
-
-
67650248913
-
Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide
-
Ahmed A, Fujisawa T, Niu XL, Ahmad S, Al-Ani B, et al. (2009) Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide. Circ Res 104: 1333-1336.
-
(2009)
Circ Res
, vol.104
, pp. 1333-1336
-
-
Ahmed, A.1
Fujisawa, T.2
Niu, X.L.3
Ahmad, S.4
Al-Ani, B.5
-
33
-
-
0032102292
-
Nitric oxide synthase modulates angiogenesis in response to tissue ischemia
-
Murohara T, Asahara T, Silver M, Bauters C, Masuda H, et al. (1998) Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest 101: 2567-2578.
-
(1998)
J Clin Invest
, vol.101
, pp. 2567-2578
-
-
Murohara, T.1
Asahara, T.2
Silver, M.3
Bauters, C.4
Masuda, H.5
-
34
-
-
2642597076
-
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
-
Papapetropoulos A, Garcia-Cardena G, Madri JA, Sessa WC, (1997) Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest 100: 3131-3139.
-
(1997)
J Clin Invest
, vol.100
, pp. 3131-3139
-
-
Papapetropoulos, A.1
Garcia-Cardena, G.2
Madri, J.A.3
Sessa, W.C.4
-
35
-
-
0037358570
-
Molecular pathways regulating mobilization of marrow-derived stem cells for tissue revascularization
-
Rabbany SY, Heissig B, Hattori K, Rafii S, (2003) Molecular pathways regulating mobilization of marrow-derived stem cells for tissue revascularization. Trends Mol Med 9: 109-117.
-
(2003)
Trends Mol Med
, vol.9
, pp. 109-117
-
-
Rabbany, S.Y.1
Heissig, B.2
Hattori, K.3
Rafii, S.4
-
36
-
-
3042590902
-
Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis
-
Bazzoni G, Dejana E, (2004) Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Physiol Rev 84: 869-901.
-
(2004)
Physiol Rev
, vol.84
, pp. 869-901
-
-
Bazzoni, G.1
Dejana, E.2
-
38
-
-
14844360656
-
Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease
-
Zhao YD, Courtman DW, Deng Y, Kugathasan L, Zhang Q, et al. (2005) Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease. Circ Res 96: 442-450.
-
(2005)
Circ Res
, vol.96
, pp. 442-450
-
-
Zhao, Y.D.1
Courtman, D.W.2
Deng, Y.3
Kugathasan, L.4
Zhang, Q.5
-
39
-
-
0028122465
-
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
-
Dumont DJ, Gradwohl G, Fong GH, Puri MC, Gertsenstein M, et al. (1994) Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev 8: 1897-1909.
-
(1994)
Genes Dev
, vol.8
, pp. 1897-1909
-
-
Dumont, D.J.1
Gradwohl, G.2
Fong, G.H.3
Puri, M.C.4
Gertsenstein, M.5
-
40
-
-
33744544135
-
Transgenic expression of Angiopoietin 1 in the liver leads to changes in lymphatic and blood vessel architecture
-
Haninec AL, Voskas D, Needles A, Brown AS, Foster FS, et al. (2006) Transgenic expression of Angiopoietin 1 in the liver leads to changes in lymphatic and blood vessel architecture. Biochem Biophys Res Commun 345: 1299-1307.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 1299-1307
-
-
Haninec, A.L.1
Voskas, D.2
Needles, A.3
Brown, A.S.4
Foster, F.S.5
|