메뉴 건너뛰기




Volumn 50, Issue 12, 2012, Pages 4239-4245

Neuroprotective effects of Schisandrin B against transient focal cerebral ischemia in Sprague-Dawley rats

Author keywords

Anti inflammatory; Matrix metalloproteinase; Microglial; Middle cerebral artery occlusion; Schisandra; Schisandrin B

Indexed keywords

GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; SCHIZANDRIN B; TUMOR NECROSIS FACTOR ALPHA;

EID: 84866669177     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.08.047     Document Type: Article
Times cited : (73)

References (57)
  • 3
    • 0033512004 scopus 로고    scopus 로고
    • Inflammatory mediators and stroke: new opportunities for novel therapeutics
    • Barone F.C., Feuerstein G.Z. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J. Cereb. Blood Flow Metab. 1999, 19:819-834.
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , pp. 819-834
    • Barone, F.C.1    Feuerstein, G.Z.2
  • 4
    • 0028884634 scopus 로고
    • HU-211, a novel noncompetitive N-methyl-D-aspartate antagonist, improves neurological deficit and reduces infarct volume after reversible focal cerebral ischemia in the rat
    • Belayev L., Busto R., Zhao W., Ginsberg M.D. HU-211, a novel noncompetitive N-methyl-D-aspartate antagonist, improves neurological deficit and reduces infarct volume after reversible focal cerebral ischemia in the rat. Stroke 1995, 26:2313-2319.
    • (1995) Stroke , vol.26 , pp. 2313-2319
    • Belayev, L.1    Busto, R.2    Zhao, W.3    Ginsberg, M.D.4
  • 5
    • 0029839695 scopus 로고    scopus 로고
    • Middle cerebral artery occlusion in the rat by intraluminal suture: neurological and pathological evaluation of an improved model
    • Belayev L., Alonso O.F., Busto R., Zhao W., Ginsberg M.D. Middle cerebral artery occlusion in the rat by intraluminal suture: neurological and pathological evaluation of an improved model. Stroke 1996, 27:1616-1623.
    • (1996) Stroke , vol.27 , pp. 1616-1623
    • Belayev, L.1    Alonso, O.F.2    Busto, R.3    Zhao, W.4    Ginsberg, M.D.5
  • 6
    • 0034652558 scopus 로고    scopus 로고
    • Tumor necrosis factor-α mRNA expression in early multiple sclerosis lesions: correlation with demyelinating activity and oligodendrocyte pathology
    • Bitsch A., Kuhlmann T., Da Costa C., Bunkowski S., Polak T., Bruck W. Tumor necrosis factor-α mRNA expression in early multiple sclerosis lesions: correlation with demyelinating activity and oligodendrocyte pathology. Glia 2000, 29:366-375.
    • (2000) Glia , vol.29 , pp. 366-375
    • Bitsch, A.1    Kuhlmann, T.2    Da Costa, C.3    Bunkowski, S.4    Polak, T.5    Bruck, W.6
  • 7
    • 0026702955 scopus 로고
    • Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
    • Boje K.M., Arora P.K. Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res. 1992, 587:250-256.
    • (1992) Brain Res. , vol.587 , pp. 250-256
    • Boje, K.M.1    Arora, P.K.2
  • 8
    • 46449093978 scopus 로고    scopus 로고
    • Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, and protects against cerebral ischemia/reperfusion injury in rats
    • Chen N., Chiu P.Y., Ko K.M. Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, and protects against cerebral ischemia/reperfusion injury in rats. Biol. Pharm. Bull. 2008, 31:1387-1391.
    • (2008) Biol. Pharm. Bull. , vol.31 , pp. 1387-1391
    • Chen, N.1    Chiu, P.Y.2    Ko, K.M.3
  • 9
    • 9444228870 scopus 로고    scopus 로고
    • Schisandrin B protects myocardial ischemia-reperfusion injury partly by inducing Hsp25 and Hsp70 expression in rats
    • Chiu P.Y., Ko K.M. Schisandrin B protects myocardial ischemia-reperfusion injury partly by inducing Hsp25 and Hsp70 expression in rats. Mol. Cell. Biochem. 2004, 266:139-144.
    • (2004) Mol. Cell. Biochem. , vol.266 , pp. 139-144
    • Chiu, P.Y.1    Ko, K.M.2
  • 10
    • 33747319849 scopus 로고    scopus 로고
    • Chronic Schisandrin B treatment improves mitochondrial antioxidant status and tissue heat shock protein production in various tissues of young adult and middle-aged rats
    • Chiu P.Y., Leung H.Y., Poon M.K., Ko K.M. Chronic Schisandrin B treatment improves mitochondrial antioxidant status and tissue heat shock protein production in various tissues of young adult and middle-aged rats. Biogerontology 2006, 7:199-210.
    • (2006) Biogerontology , vol.7 , pp. 199-210
    • Chiu, P.Y.1    Leung, H.Y.2    Poon, M.K.3    Ko, K.M.4
  • 11
    • 0032211291 scopus 로고    scopus 로고
    • An integrated analysis of the progression of cell responses induced by permanent focal middle cerebral artery occlusion in the rat
    • Davies C.A., Loddick S.A., Stroemer R.P., Hunt J., Rothwell N.J. An integrated analysis of the progression of cell responses induced by permanent focal middle cerebral artery occlusion in the rat. Exp. Neurol. 1998, 154:199-212.
    • (1998) Exp. Neurol. , vol.154 , pp. 199-212
    • Davies, C.A.1    Loddick, S.A.2    Stroemer, R.P.3    Hunt, J.4    Rothwell, N.J.5
  • 12
    • 0024414097 scopus 로고
    • Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats
    • De Ryck M., Van Reempts J., Borgers M., Wauquier A., Janssen P.A. Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats. Stroke 1989, 20:1383-1390.
    • (1989) Stroke , vol.20 , pp. 1383-1390
    • De Ryck, M.1    Van Reempts, J.2    Borgers, M.3    Wauquier, A.4    Janssen, P.A.5
  • 13
    • 80052844339 scopus 로고    scopus 로고
    • Matrix metalloproteinases as drug targets in ischemia/reperfusion injury
    • Dejonckheere E., Vandenbroucke R.E., Libert C. Matrix metalloproteinases as drug targets in ischemia/reperfusion injury. Drug Discov. Today 2011, 16:762-778.
    • (2011) Drug Discov. Today , vol.16 , pp. 762-778
    • Dejonckheere, E.1    Vandenbroucke, R.E.2    Libert, C.3
  • 14
    • 0041337013 scopus 로고    scopus 로고
    • Ninjin-yoei-to (Ren-Shen-Yang-Rong-Tang) and polygalae radix improves scopolamine-induced impairment of passive avoidance response in mice
    • Egashira N., Yuzurihara M., Hattori N., et al. Ninjin-yoei-to (Ren-Shen-Yang-Rong-Tang) and polygalae radix improves scopolamine-induced impairment of passive avoidance response in mice. Phytomedicine 2003, 10:467-473.
    • (2003) Phytomedicine , vol.10 , pp. 467-473
    • Egashira, N.1    Yuzurihara, M.2    Hattori, N.3
  • 15
    • 0031666486 scopus 로고    scopus 로고
    • The role of cytokines in the neuropathology of stroke and neurotrauma
    • Feuerstein G.Z., Wang X., Barone F.C. The role of cytokines in the neuropathology of stroke and neurotrauma. NeuroImmunoModulation 1998, 5:143-159.
    • (1998) NeuroImmunoModulation , vol.5 , pp. 143-159
    • Feuerstein, G.Z.1    Wang, X.2    Barone, F.C.3
  • 16
    • 0029088913 scopus 로고
    • Anti-human immunodeficiency virus (HIV) activities of halogenated gomisin J derivatives, new non-nucleoside inhibitors of HIV type 1 reverse transcriptase
    • Fujihashi T., Hara H., Sakata T., Mori K., Higuchi H., Tanaka A., Kaji H., Kaji A. Anti-human immunodeficiency virus (HIV) activities of halogenated gomisin J derivatives, new non-nucleoside inhibitors of HIV type 1 reverse transcriptase. Antimicrob. Agents Chemother. 1995, 39:2000-2007.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 2000-2007
    • Fujihashi, T.1    Hara, H.2    Sakata, T.3    Mori, K.4    Higuchi, H.5    Tanaka, A.6    Kaji, H.7    Kaji, A.8
  • 17
    • 0028959038 scopus 로고
    • Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation
    • Garcia J.H., Wagner S., Liu K.F., Hu X.J. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke 1995, 26:627-634.
    • (1995) Stroke , vol.26 , pp. 627-634
    • Garcia, J.H.1    Wagner, S.2    Liu, K.F.3    Hu, X.J.4
  • 18
    • 0033505281 scopus 로고    scopus 로고
    • Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction
    • Gasche Y., Fujimura M., Morita-Fujimura Y., Copin J., Kawase M., Massengale J., et al. Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction. J. Cereb. Blood Flow Metab. 1999, 19:1020-1028.
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , pp. 1020-1028
    • Gasche, Y.1    Fujimura, M.2    Morita-Fujimura, Y.3    Copin, J.4    Kawase, M.5    Massengale, J.6
  • 19
  • 20
    • 0036262303 scopus 로고    scopus 로고
    • Antioxidant therapy in acute central nervous system injury: current state
    • Gilgun-Sherki Y., Rosenbaum Z., Melamed E., Offen D. Antioxidant therapy in acute central nervous system injury: current state. Pharmacol. Rev. 2002, 54:271-284.
    • (2002) Pharmacol. Rev. , vol.54 , pp. 271-284
    • Gilgun-Sherki, Y.1    Rosenbaum, Z.2    Melamed, E.3    Offen, D.4
  • 21
    • 21844450866 scopus 로고    scopus 로고
    • A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia
    • Gu Z., Cui J., Brown S., Fridman R., Mobashery S., Strongin A.Y., Lipton S.A. A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. J. Neurosci. 2005, 25:6401-6408.
    • (2005) J. Neurosci. , vol.25 , pp. 6401-6408
    • Gu, Z.1    Cui, J.2    Brown, S.3    Fridman, R.4    Mobashery, S.5    Strongin, A.Y.6    Lipton, S.A.7
  • 22
    • 0021182748 scopus 로고
    • Antihepatotoxic actions of lignoids from Schisandra chinensis fruits
    • Hikino H., Kiso Y., Taguchi H., Ikeya Y. Antihepatotoxic actions of lignoids from Schisandra chinensis fruits. Planta Med. 1984, 50:213-218.
    • (1984) Planta Med. , vol.50 , pp. 213-218
    • Hikino, H.1    Kiso, Y.2    Taguchi, H.3    Ikeya, Y.4
  • 23
    • 2342599464 scopus 로고
    • 13C NMR magnetic resonance spectroscopy of dibenzocyclooctadiene lignans
    • Ikeya Y., Taguchi H., Sasaki H., Nakajima K., Yoshioka I. 13C NMR magnetic resonance spectroscopy of dibenzocyclooctadiene lignans. Chem. Pharm. Bull. 1980, 27:1383-1390.
    • (1980) Chem. Pharm. Bull. , vol.27 , pp. 1383-1390
    • Ikeya, Y.1    Taguchi, H.2    Sasaki, H.3    Nakajima, K.4    Yoshioka, I.5
  • 24
    • 77952513645 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: role of inflammatory cells
    • Jin R., Yang G., Li G. Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J. Leukoc. Biol. 2010, 87:779-789.
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 779-789
    • Jin, R.1    Yang, G.2    Li, G.3
  • 26
    • 0021816338 scopus 로고
    • Mechanism of antihepatotoxic activity of wuweizisu C and gomisin A
    • Kiso Y., Tohkin M., Hikino H., Ikeya Y., Taguchi H. Mechanism of antihepatotoxic activity of wuweizisu C and gomisin A. Planta Med. 1985, 51:331-334.
    • (1985) Planta Med. , vol.51 , pp. 331-334
    • Kiso, Y.1    Tohkin, M.2    Hikino, H.3    Ikeya, Y.4    Taguchi, H.5
  • 27
    • 0034983189 scopus 로고    scopus 로고
    • Schisandrin B modulates the ischemia-reperfusion induced changes in non-enzymatic antioxidant levels in isolated-perfused rat hearts
    • Ko K.M., Yiu H.Y. Schisandrin B modulates the ischemia-reperfusion induced changes in non-enzymatic antioxidant levels in isolated-perfused rat hearts. Mol. Cell. Biochem. 2001, 220:141-147.
    • (2001) Mol. Cell. Biochem. , vol.220 , pp. 141-147
    • Ko, K.M.1    Yiu, H.Y.2
  • 28
    • 0028907612 scopus 로고
    • Effect of a lignan-enriched Fructus Schisandrae extract on hepatic glutathione status in rats: protection against carbon tetracholoride toxicity
    • Ko K.M., Ip S.P., Poon M.K.T., Wu S.S., Che C.T., Ng K.H., Kong T.C. Effect of a lignan-enriched Fructus Schisandrae extract on hepatic glutathione status in rats: protection against carbon tetracholoride toxicity. Planta Med. 1995, 61:134-137.
    • (1995) Planta Med. , vol.61 , pp. 134-137
    • Ko, K.M.1    Ip, S.P.2    Poon, M.K.T.3    Wu, S.S.4    Che, C.T.5    Ng, K.H.6    Kong, T.C.7
  • 30
    • 3042730654 scopus 로고    scopus 로고
    • Induction of caspase-mediated cell death by matrix metalloproteinases in cerebral endothelial cells after hypoxia-reoxygenation
    • Lee S.R., Lo E.H. Induction of caspase-mediated cell death by matrix metalloproteinases in cerebral endothelial cells after hypoxia-reoxygenation. J. Cereb. Blood Flow Metab. 2004, 24:720-727.
    • (2004) J. Cereb. Blood Flow Metab. , vol.24 , pp. 720-727
    • Lee, S.R.1    Lo, E.H.2
  • 31
    • 0030769136 scopus 로고    scopus 로고
    • Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion
    • Lehrmann E., Christensen T., Zimmer J., Diemer N.H., Finsen B. Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion. J. Comp. Neurol. 1997, 386:461-476.
    • (1997) J. Comp. Neurol. , vol.386 , pp. 461-476
    • Lehrmann, E.1    Christensen, T.2    Zimmer, J.3    Diemer, N.H.4    Finsen, B.5
  • 32
    • 0345258379 scopus 로고
    • Chapter Title: Hepato-Pharmacology of Fructus schisandrae
    • Chang HM, et al. (Eds.), Advances in Chinese Medical Materials Research. Singapore
    • Liu, G.T., 1985. In: Chang HM, et al. (Eds.), Advances in Chinese Medical Materials Research. Singapore. Chapter Title: Hepato-Pharmacology of Fructus schisandrae. World Scientific Publishing Co., pp. 257-268.
    • (1985) World Scientific Publishing Co , pp. 257-268
    • Liu, G.T.1
  • 33
    • 0036644958 scopus 로고    scopus 로고
    • Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases
    • Lo E., Wang X., Cuzner M. Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases. J. Neurosci. Res. 2002, 69:1-9.
    • (2002) J. Neurosci. Res. , vol.69 , pp. 1-9
    • Lo, E.1    Wang, X.2    Cuzner, M.3
  • 34
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • Lo E.H., Dalkara T., Moskowitz M.A. Mechanisms, challenges and opportunities in stroke. Nat. Rev. Neurosci. 2003, 4:399-415.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 35
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20:84-91.
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 36
    • 0345563285 scopus 로고    scopus 로고
    • Optimal depth and duration of mild hypothermia in a focal model of transient cerebral ischemia: effects on neurologic outcome, infarct size, apoptosis, and inflammation
    • Maier C.M., Ahern K., Cheng M.L., Lee J.E., Yenari M.A., Steinberg G.K. Optimal depth and duration of mild hypothermia in a focal model of transient cerebral ischemia: effects on neurologic outcome, infarct size, apoptosis, and inflammation. Stroke 1998, 29:2171-2180.
    • (1998) Stroke , vol.29 , pp. 2171-2180
    • Maier, C.M.1    Ahern, K.2    Cheng, M.L.3    Lee, J.E.4    Yenari, M.A.5    Steinberg, G.K.6
  • 38
    • 79960703787 scopus 로고    scopus 로고
    • The effects of a novel anti-inflammatory compound (AHI-805) on cyclooxygenase enzymes and the recovery of ischaemia injured equine jejunum ex vivo
    • Marshall J.F., Bhatnagar A.S., Bowman S.G., Morris N.N., Skorich D.A., Redding C.D., Blikslager A.T. The effects of a novel anti-inflammatory compound (AHI-805) on cyclooxygenase enzymes and the recovery of ischaemia injured equine jejunum ex vivo. Equine Vet. J. 2011, 43:106-111.
    • (2011) Equine Vet. J. , vol.43 , pp. 106-111
    • Marshall, J.F.1    Bhatnagar, A.S.2    Bowman, S.G.3    Morris, N.N.4    Skorich, D.A.5    Redding, C.D.6    Blikslager, A.T.7
  • 40
    • 0020784280 scopus 로고
    • The constituents of Schisandra chinensis Baill. XIII. Quantitative analysis of lignans in the fruits of Schisandra chinensis Baill. by high performance liquid chromatography
    • Nakajima K., Taguchi H., Ikeya Y., Endo Y., Yosioka I. The constituents of Schisandra chinensis Baill. XIII. Quantitative analysis of lignans in the fruits of Schisandra chinensis Baill. by high performance liquid chromatography. Yakugaku Zasshi 1983, 103:743-749.
    • (1983) Yakugaku Zasshi , vol.103 , pp. 743-749
    • Nakajima, K.1    Taguchi, H.2    Ikeya, Y.3    Endo, Y.4    Yosioka, I.5
  • 41
    • 0030029701 scopus 로고    scopus 로고
    • Tumor necrosis factor-α is elevated in serum and cerebrospinal fluid in multiple sclerosis and inflammatory neuropathies
    • Rentzos M., Nikolaou C., Rombos A., Voumvourakis K., Segditsa I., Papageorgiou C. Tumor necrosis factor-α is elevated in serum and cerebrospinal fluid in multiple sclerosis and inflammatory neuropathies. J. Neurol. 1996, 243:165-170.
    • (1996) J. Neurol. , vol.243 , pp. 165-170
    • Rentzos, M.1    Nikolaou, C.2    Rombos, A.3    Voumvourakis, K.4    Segditsa, I.5    Papageorgiou, C.6
  • 42
    • 0036460593 scopus 로고    scopus 로고
    • Gelatinase B and TIMP-1 are regulated in a cell- and time-dependent manner in association with neuronal death and glial reactivity after global forebrain ischemia
    • Rivera S., Ogier C., Jourquin J., Timsit S., Szklarczyk A.W., Miller K., Gearing A.J., Kaczmarek L., Khrestchatisky M. Gelatinase B and TIMP-1 are regulated in a cell- and time-dependent manner in association with neuronal death and glial reactivity after global forebrain ischemia. Eur. J. Neurosci. 2002, 15:19-32.
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 19-32
    • Rivera, S.1    Ogier, C.2    Jourquin, J.3    Timsit, S.4    Szklarczyk, A.W.5    Miller, K.6    Gearing, A.J.7    Kaczmarek, L.8    Khrestchatisky, M.9
  • 43
    • 0030899195 scopus 로고    scopus 로고
    • Metalloproteinase inhibition blocks edema in intracerebral hemorrhage in the rat
    • Rosenberg G., Navratil M. Metalloproteinase inhibition blocks edema in intracerebral hemorrhage in the rat. Neurology 1997, 48:921-926.
    • (1997) Neurology , vol.48 , pp. 921-926
    • Rosenberg, G.1    Navratil, M.2
  • 44
    • 0028973084 scopus 로고
    • Tumor necrosis factor-α-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window
    • Rosenberg G.A., Estrada E.Y., Dencoff J.E., Stetler-Stevenson W.G. Tumor necrosis factor-α-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window. Brain Res. 1995, 703:151-155.
    • (1995) Brain Res. , vol.703 , pp. 151-155
    • Rosenberg, G.A.1    Estrada, E.Y.2    Dencoff, J.E.3    Stetler-Stevenson, W.G.4
  • 45
    • 0035793934 scopus 로고    scopus 로고
    • Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures
    • Rosenberg G.A., Cunningham L.A., Wallace J., Alexander S., Estrada E.Y., Grossetete M., Razhagi A., Miller K., Gearing A. Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures. Brain Res. 2001, 893:104-112.
    • (2001) Brain Res. , vol.893 , pp. 104-112
    • Rosenberg, G.A.1    Cunningham, L.A.2    Wallace, J.3    Alexander, S.4    Estrada, E.Y.5    Grossetete, M.6    Razhagi, A.7    Miller, K.8    Gearing, A.9
  • 46
    • 0037196121 scopus 로고    scopus 로고
    • Free radical scavenging and antioxidative activity of caffeic acid amide and ester analogues: structure-activity relationship
    • Son S., Lewis B.A. Free radical scavenging and antioxidative activity of caffeic acid amide and ester analogues: structure-activity relationship. J. Agric. Food Chem. 2002, 50:468-472.
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 468-472
    • Son, S.1    Lewis, B.A.2
  • 47
    • 79952232564 scopus 로고    scopus 로고
    • Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells
    • Song J.X., Lin X., Wong R.N., Sze S.C., Tong Y., Shaw P.C., Zhang Y.B. Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells. Phytother Res. 2011, 25:435-443.
    • (2011) Phytother Res. , vol.25 , pp. 435-443
    • Song, J.X.1    Lin, X.2    Wong, R.N.3    Sze, S.C.4    Tong, Y.5    Shaw, P.C.6    Zhang, Y.B.7
  • 48
    • 80055017674 scopus 로고    scopus 로고
    • Effect of baicalin on matrix metalloproteinase-9 expression and blood-brain barrier permeability following focal cerebral ischemia in rats
    • Tu X.K., Yang W.Z., Liang R.S., Shi S.S., Chen J.P., Chen C.M., Wang C.H., Xie H.S., Chen Y., Ouyang L.Q. Effect of baicalin on matrix metalloproteinase-9 expression and blood-brain barrier permeability following focal cerebral ischemia in rats. Neurochem. Res. 2011, 36:2022-2028.
    • (2011) Neurochem. Res. , vol.36 , pp. 2022-2028
    • Tu, X.K.1    Yang, W.Z.2    Liang, R.S.3    Shi, S.S.4    Chen, J.P.5    Chen, C.M.6    Wang, C.H.7    Xie, H.S.8    Chen, Y.9    Ouyang, L.Q.10
  • 49
    • 0028053465 scopus 로고
    • Inhibition by gomisin C (a lignan from Schisandra chinensis) of the respiratory burst of rat neutrophils
    • Wang J.P., Raung S.L., Hsu M.F., Chen C.C. Inhibition by gomisin C (a lignan from Schisandra chinensis) of the respiratory burst of rat neutrophils. Br. J. Pharmacol. 1994, 113:945-953.
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 945-953
    • Wang, J.P.1    Raung, S.L.2    Hsu, M.F.3    Chen, C.C.4
  • 52
    • 0026565227 scopus 로고
    • Antioxidant activity of two dibenzocyclooctene lignans on the aged and ischemic brain in rats
    • Xue J.Y., Liu G.T., Wei H.L., Pan Y. Antioxidant activity of two dibenzocyclooctene lignans on the aged and ischemic brain in rats. Free Radical Biol. Med. 1992, 12:127-135.
    • (1992) Free Radical Biol. Med. , vol.12 , pp. 127-135
    • Xue, J.Y.1    Liu, G.T.2    Wei, H.L.3    Pan, Y.4
  • 53
    • 0027240206 scopus 로고
    • Preventive effect of gomisin A, a lignan component of Schisandra fruits, on acetaminophen-induced hepatotoxicity in rats
    • Yamada S., Murawaki Y., Kawasaki H. Preventive effect of gomisin A, a lignan component of Schisandra fruits, on acetaminophen-induced hepatotoxicity in rats. Biochem. Pharmacol. 1993, 46:1081-1085.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 1081-1085
    • Yamada, S.1    Murawaki, Y.2    Kawasaki, H.3
  • 54
    • 0026565258 scopus 로고
    • Gomisin A inhibits tumor promotion by 12-o-tetra-decanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin
    • Yasukawa K., Ikeya Y., Mitsuhashi H., Iwasaki M., Aburada M., Nakagawa S., Takeuchi M., Takido M. Gomisin A inhibits tumor promotion by 12-o-tetra-decanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Oncology 1992, 49:68-71.
    • (1992) Oncology , vol.49 , pp. 68-71
    • Yasukawa, K.1    Ikeya, Y.2    Mitsuhashi, H.3    Iwasaki, M.4    Aburada, M.5    Nakagawa, S.6    Takeuchi, M.7    Takido, M.8
  • 55
    • 0032769002 scopus 로고    scopus 로고
    • Schisandrin B protects against myocardial ischemia-reperfusion injury by enhancing myocardial glutathione antioxidant status
    • Yim T.K., Ko K.M. Schisandrin B protects against myocardial ischemia-reperfusion injury by enhancing myocardial glutathione antioxidant status. Mol. Cell. Biochem. 1999, 196:151-156.
    • (1999) Mol. Cell. Biochem. , vol.196 , pp. 151-156
    • Yim, T.K.1    Ko, K.M.2
  • 56
    • 0030670117 scopus 로고    scopus 로고
    • Transient middle cerebral artery occlusion by intraluminal suture: II. Neurological deficits, and pixel-based correlation of histopathology with local blood t10w and glucose utilization
    • Zhao W., Belayev L., Ginsberg M.D. Transient middle cerebral artery occlusion by intraluminal suture: II. Neurological deficits, and pixel-based correlation of histopathology with local blood t10w and glucose utilization. J. Cereb. Blood Flow Metab. 1997, 17:1281-1290.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 1281-1290
    • Zhao, W.1    Belayev, L.2    Ginsberg, M.D.3
  • 57
    • 0032797602 scopus 로고    scopus 로고
    • Evaluation of the protective effects of Schisandra chinensis on Phase I drug metabolism using a CCl4 intoxication model
    • Zhu M., Lin K.F., Yeung R.Y., Li R.C. Evaluation of the protective effects of Schisandra chinensis on Phase I drug metabolism using a CCl4 intoxication model. J. Ethnopharmacol. 1999, 67:61-68.
    • (1999) J. Ethnopharmacol. , vol.67 , pp. 61-68
    • Zhu, M.1    Lin, K.F.2    Yeung, R.Y.3    Li, R.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.