Modification of rat model of sciatica induced by lumber disc herniation and the anti-inflammatory effect of osthole given by epidural catheterization

Pharmacology

Volumn 90, Issue 5-6, 2012, Pages 251-263

  Wei, Ming ^a   Mo, Sui Lin ^b   Nabar, Neel R ^d   Chen, Yuling ^e   Zhang, Jin Jun ^a   He, Qiu Lan ^a   Zou, Xue Nong ^c   Liu, Xian Guo ^a   Sun, Lai Bao ^a   Zhou, Shu Feng ^d  

^a SUN YAT SEN UNIVERSITY   (China)

^b University of Chinese Medicine   (China)

^c First Affiliated Hospital   (China)

^d UNIVERSITY OF SOUTH FLORIDA   (United States)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Cyclooxygenase 2; Nitric oxide synthase; Nucleus pulposus; Osthole; Sciatica

Indexed keywords

CYCLOOXYGENASE 2; NITRIC OXIDE SYNTHASE; OSTHOLE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG EFFECT; DRUG EFFICACY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME REGULATION; GENE OVEREXPRESSION; HYPERALGESIA; INFLAMMATION; ISCHIALGIA; LUMBAR DISK HERNIA; MALE; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RAT; RELIABILITY; SIMULATION; TREATMENT RESPONSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CATHETERIZATION; COUMARINS; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; INJECTIONS, EPIDURAL; INTERVERTEBRAL DISC DISPLACEMENT; LUMBAR VERTEBRAE; MALE; NITRIC OXIDE SYNTHASE; PAIN; RATS; RATS, SPRAGUE-DAWLEY; SCIATICA;

EID: 84866668451     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000340023     Document Type: Article

References (33)

1. Hoy D, Mar ch L, Brooks P, Woolf A, Blyth F, Vos T, Buchbinder R: Measuring the global burden of low back pain. Best Pract Res Clin Rheumatol 2010;24:155-165.
2. Kent PM, Keating JL: The epidemiology of low back pain in primary care. Chiropr Osteopat 2005;13:13.
3. Thelin A, Holmberg S, Thelin N: Functioning in neck and low back pain from a 12-year perspective: a prospective population-based study. J Rehabil Med 2008;40:555-561.
4. Steenstra IA, Verbeek JH, Heymans MW, Bongers PM: Prognostic factors for duration of sick leave in patients sick listed with acute low back pain: a systematic review of the literature. Occup Environ Med 2005;62: 851-860. (Pubitemid 41729775)
5. Kawakami M, Weinstein JN, Spratt KF, Chatani K, Traub RJ, Meller ST, Gebhart GF: Experimental lumbar radiculopathy. Immunohistochemical and quantitative demonstrations of pain induced by lumbar nerve root irritation of the rat. Spine 1994;19:1780-1794. (Pubitemid 24314190)
6. Lipetz JS: Pathophysiology of inflammatory, degenerative, and compressive radiculopathies. Phys Med Rehabil Clin N Am 2002;13: 439-449.
7. Kawakami M, Tamaki T, Hayashi N, Hashizume H, Nishi H: Possible mechanism of painful radiculopathy in lumbar disc herniation. Clin Orthop Relat Res 1998;351:241-251. (Pubitemid 28275409)
8. Kawakami M, Matsumoto T, Kuribayashi K, Tamaki T: mRNA expression of interleukins, phospholipase A2, and nitric oxide synthase in the nerve root and dorsal root ganglion induced by autologous nucleus pulposus in the rat. J Orthop Res 1999;17:941-946.
9. Kawakami M, Matsumoto T, Hashizume H, Kuribayashi K, Tamaki T: Epidural injection of cyclooxygenase-2 inhibitor attenuates pain-related behavior following application of nucleus pulposus to the nerve root in the rat. J Orthop Res 2002;20:376-381. (Pubitemid 34218286)
10. Kawakami M, Tamaki T, Weinstein JN, Hashizume H, Nishi H, Meller ST: Pathomechanism of pain-related behavior produced by allografts of intervertebral disc in the rat. Spine 1996;21:2101-2107. (Pubitemid 26330595)
11. Onda A, Murata Y, Rydevik B, Larsson K, Kikuchi S, Olmarker K: Infliximab attenuates immunoreactivity of brain-derived neurotrophic factor in a rat model of herniated nucleus pulposus. Spine 2004;29:1857-1861. (Pubitemid 39181041)
12. Lin XJ, Chen CY: Advances on study of treatment of lumbar disk herniation by Chinese medicinal herbs (in Chinese). Zhongguo Zhong Yao Za Zhi 2007;32:186-191.
13. Sasaki T, Fassler R, Hohenester E: Laminin: The crux of basement membrane assembly. J Cell Biol 2004;164:959-963. (Pubitemid 38429121)
14. Sasaki N, Kikuchi S, Konno S, Sekiguchi M, Watanabe K: Anti-TNF-α antibody reduces pain-behavioral changes induced by epidural application of nucleus pulposus in a rat model depending on the timing of administration. Spine 2007;32:413-416.
15. Liu J, Zhang W, Zhou L, Wang X, Lian Q: Anti-inflammatory effect and mechanism of osthole in rats. Zhong Yao Cai 2005;28: 1002-1006.
16. Qin LP, Wang HB, Zhang JQ: Effects of osthol and total-coumarins from Cnidium monnieri on immunological function in kidney Yang deficiency mice (in Chinese). Zhongguo Zhong Xi Yi Jie He Za Zhi 1995;15: 547-549.
17. Xu X, Zhang Y, Qu D, Jiang T, Li S: Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway. J Exp Clin Cancer Res 2011;30:33.
18. Li L, Qiu Y: Local anesthetic action of osthole. Shanghai Lab Anim Sci 1997;17: 133-136.
19. He QL, Chen Y, Qin J, Mo SL, Wei M, Zhang JJ, Li MN, Zou XN, Zhou SF, Sun LB: Osthole, a herbal compound, alleviates nucleus pulposus-evoked nociceptive responses through the suppression of overexpression of acid-sensing ion channel 3 (ASIC3) in rat dorsal root ganglion. Med Sci Monit 2012;18: BR229-BR236.
20. Ohtori S, Inoue G, Koshi T, Ito T, Doya H, Saito T, Moriya H, Takahashi K: Up-regulation of acid-sensing ion channel 3 in dorsal root ganglion neurons following application of nucleus pulposus on nerve root in rats. Spine 2006;31:2048-2052.
21. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL: Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods 1994;53:55-63. (Pubitemid 24238751)
22. Dawson TM, Bredt DS, Fotuhi M, Hwang PM, Snyder SH: Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc Natl Acad Sci USA 1991;88:7797-7801. (Pubitemid 21915241)
23. Dou W, Jiao Y, Goorha S, Raghow R, Ballou LR: Nociception and the differential expression of cyclooxygenase-1 (COX-1), the COX-1 variant retaining intron-1 (COX- 1v), and COX-2 in mouse dorsal root ganglia (DRG). Prostaglandins Other Lipid Mediat 2004;74:29-43. (Pubitemid 39360218)
24. Wu G, Robertson DH, Brooks CL 3rd, Vieth M: Detailed analysis of grid-based molecular docking: a case study of CDOCKER-A CHARMm-based MD docking algorithm. J Comput Chem 2003;24:1549-1562.
25. Brisby H, Byrod G, Olmarker K, Miller VM, Aoki Y, Rydevik B: Nitric oxide as a mediator of nucleus pulposus-induced effects on spinal nerve roots. J Orthop Res 2000;18:815-820.
26. Ohtori S, Takahashi K, Aoki Y, Doya H, Ozawa T, Saito T, Moriya H: Spinal neural cyclooxygenase-2 mediates pain caused in a rat model of lumbar disk herniation. J Pain 2004;5:385-391. (Pubitemid 39410107)
27. Choi SS, Kim YC, Lim YJ, Lee CJ, Lee PB, Lee SC, Sim WS, Choi YL: The neurological safety of epidural gabapentin in rats: a light microscopic examination. Anesth Analg 2005; 101:1422-1426. (Pubitemid 41531882)
28. Picot D, Loll PJ, Garavito RM: The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature 1994;367: 243-249. (Pubitemid 24051139)
29. Kurumbail RG, Stevens AM, Gierse JK, Mc- Donald JJ, Stegeman RA, Pak JY, Gildehaus D, Miyashiro JM, Penning TD, Seibert K, Isakson PC, Stallings WC: Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature 1996;384: 644-648.
30. Luong C, Miller A, Barnett J, Chow J, Ramesha C, Browner MF: Flexibility of the NSAID binding site in the structure of human cyclooxygenase- 2. Nat Struct Biol 1996;3: 927-933. (Pubitemid 26398325)
31. Duggan KC, Walters MJ, Musee J, Harp JM, Kiefer JR, Oates JA, Marnett LJ: Molecular basis for cyclooxygenase inhibition by the nonsteroidal anti-inflammatory drug naproxen. J Biol Chem 2010;285:34950-34959.
32. Delker SL, Xue F, Li H, Jamal J, Silverman RB, Poulos TL: Role of zinc in isoformselective inhibitor binding to neuronal nitric oxide synthase. Biochemistry 2010;49: 10803-10810.
33. Cai TB, Lu D, Wang PG: N-Hydroxyguanidines as substrates of nitric oxide synthases. Curr Top Med Chem 2005;5:721-736. (Pubitemid 41179730)