FM19G11 favors spinal cord injury regeneration and stem cell self-renewal by mitochondrial uncoupling and glucose metabolism induction

Stem Cells

Volumn 30, Issue 10, 2012, Pages 2221-2233

  Rodríguez Jiménez, Francisco Javier ^a   Alastrue Agudo, Ana ^a   Erceg, Slaven ^b,c   Stojkovic, Miodrag ^d   Moreno Manzano, Victoria ^a  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b CABIMER Andalusian Center for Molecular Biology and Regenerative Medicine CSIC University of Seville UPO   (Spain)

^c Medical Genome Project   (Spain)

^d Spebo Medical ^*  (Serbia)

Author keywords

Ependymal stem cells; Glucose metabolism; Pharmacology; Spinal cord regeneration

Indexed keywords

BETA ACTIN; FM 19G 11; GLUCOSE; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; NOTCH1 RECEPTOR; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN INHIBITOR; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2; VIMENTIN;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL METABOLISM; CELL POPULATION; CELL RENEWAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EPENDYMA CELL; FEMALE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; IN VIVO STUDY; LOCOMOTION; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PROTEIN EXPRESSION; RAT; SPINAL CORD INJURY; SPINAL CORD REGENERATION; STEM CELL; UPREGULATION;

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; ADULT STEM CELLS; ANIMALS; BENZAMIDES; EPENDYMA; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; ION CHANNELS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NERVE REGENERATION; NEUROPROTECTIVE AGENTS; ONCOGENE PROTEIN V-AKT; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD INJURIES; TOR SERINE-THREONINE KINASES;

ANIMALIA; RATTUS;

EID: 84866657164     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1189     Document Type: Article

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