Molecular basis of weak D and DEL in Han population in Anhui Province, China

Chinese Medical Journal

Volumn 125, Issue 18, 2012, Pages 3251-3255

  Chen, Qing ^a,e   Li, Ming ^b   Li, Min ^c   Lu, Xue song ^d   Lü, Rong ^b   Sun, Jun ^a   Liu, Zhong ^b  

^a Jiangsu Province Blood Center   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

^c INSTITUTE OF DERMATOLOGY   (China)

^d SOUTHEAST UNIVERSITY   (China)

^e SOOCHOW UNIVERSITY   (China)

Author keywords

DEL phenotypes; Rh blood group system; Sequence analysis; Weak D

Indexed keywords

GENOMIC DNA; IMMUNOGLOBULIN M; RHESUS D ANTIBODY;

ADSORPTION; ALLELE; ARTICLE; BLOOD GROUP RHESUS SYSTEM; CHINA; COOMBS TEST; ELUTION; EXON; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC SCREENING; HUMAN; MULTIPLEX POLYMERASE CHAIN REACTION; NUCLEOTIDE SEQUENCE; PHENOTYPE; SEROLOGY;

ALLELES; CHINA; EXONS; HUMANS; IMMUNOGLOBULIN M; MULTIPLEX POLYMERASE CHAIN REACTION; PHENOTYPE; POLYMERASE CHAIN REACTION; RH-HR BLOOD-GROUP SYSTEM;

EID: 84866647046     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.18.010     Document Type: Article

References (33)

1. Daniels G. Human blood groups, 2nd ed. Oxford: Blackwell Science Ltd; 2002: 232-267.
2. Wagner FF, Flegel WA. The molecular basis of the Rh blood group phenotypes. Immunohematology 2004; 20: 23-36.
3. Wagner FF, Gassner C, Müller TH, Schönitzer D, Schunter F, Flegel WA. Molecular basis of weak D phenotypes. Blood 1999; 93: 385-393.
4. Flegel WA. Molecular genetics and clinical applications for RH. Transfus Apher Sci 2011; 44: 81-91.
5. Makroo RN, Raina V, Chowdhry M, Bhatia A, Gupta R, Rosamma NL. Weak D prevalence among Indian blood donors. Asian J Transfus Sci 2010; 4: 137-139.
6. Peng CT, Shih MC, Liu TC, Lin IL, Jaung SJ, Chang JG. Molecular basis for the RhD negative phenotype in Chinese. Int J Mol Med 2003; 11: 515-521.
7. Wagner FF, Frohmajer A, Flegel WA. RHD positive haplotypes in D negative Europeans. BMC Genet 2001; 2: 10.
8. Mak KH, Yan KF, Cheng SS, Yuen MY. Rh phenotypes of Chinese blood donors in Hong Kong, with special reference to weak D antigens. Transfusion 1993; 33: 348-351.
9. Wagner TW, Körmöczi GF, Buchta C, Vadon M, Lanzer G, Mayr WR, et al. Anti-D immunization by DEL red blood cells. Transfusion 2005; 520-526.
10. Yasuda H, Ohto H, Sakuma S, Ishikawa Y. Secondary anti-D immunization by Del red blood cells. Transfusion 2005; 1581-1584.
11. Kim KH, Kim KE, Woo KS, Han JY, Kim JM, Park KU. Primary anti-D immunization by DEL red blood cells. Korean J Lab Med 2009; 29: 361-365.
12. Ansart-Pirenne H, Asso-Bonnet M, Le Pennec PY, Roussel M, Patereau C, Noizat-Pirenne F. RhD variants in Caucasians: consequences for checking clinically relevant alleles. Transfusion 2004; 44: 1282-1286.
13. Flegel WA, Wagner FF, Müller TH, Gassner C. Rh phenotype prediction by DNA typing and its application to practice. Transfus Med 1998; 8: 281-302.
14. Legler TJ, Maas JH, Köhler M, Wagner T, Daniels GL, Perco P, et al. RHD sequencing: a new tool for decision making on transfusion therapy and provision of Rh prophylaxis. Transfus Med 2001; 11: 383-388.
15. http://www.uniulm.de/~wflegel/Rh/.
16. Araújo F, Rodrigues MJ, Monteiro F, Chabert T, Tavares G, Sousa G, et al. Weak D type 2 is the most prevalent weak D type in Portugal. Transfus Med 2006; 16: 63-67.
17. Muller TH, Wagner FF, Trockenbacher A, Eicher NI, Flegel WA, Schonitzer D, et al. PCR screening for common weak D types shows different distributions in three Central European populations. Transfusion 2001; 41: 45-52.
18. Wagner FF, Frohmajer A, Ladewig B, Eicher NI, Lonicer CB, Müller TH, et al. Weak D alleles express distinct phenotypes. Blood 2000; 95: 2699-2708.
19. Shao CP, Maas JH, Su YQ, Köhler M, Legler TJ. Molecular background of Rh D-positive, D-negative, Del and weak D phenotypes in Chinese. Vox Sang 2002; 83: 156-161.
20. Sun GD, Duan XM, Zhang YP, Yin ZZ, Niu XL, Li YF, et al. Molecular background of weak D type 15 as the predominant weak D type found in Chinese population. J Exp Hematol (Chin) 2006; 14: 1024-1028.
21. Lin IL, Shih MC, Hsieh MH, Liu TC, Chang SE, Lin CL, et al. Molecular basis of weak D in Taiwanese. Ann Hematol 2003; 82: 617-620.
22. Gassner C, Doescher A, Drnovsek TD, Rozman P, Eicher NI, Legler TJ, et al. Presence of RHD in serologically D-, C/E+ individuals: a European multicenter study. Transfusion 2005; 45: 527-538.
23. Chen JC, Lin TM, Chen YL, Wang YH, Jin YT, Yue CT. RHD 1227A is an important genetic marker for RhD(el) individuals. Am J Clin Pathol 2004; 122: 193-198.
24. Xu Q, Grootkerk-Tax MG, Maaskant-van Wijk PA, van der Schoot CE. Systemic analysis and zygosity determination of the RHD gene in a D-negative Chinese Han population reveals a novel D-negative RHD gene. Vox Sang 2005; 88: 35-40.
25. Yang YF, Wang YH, Chen JC, Eng HL, Lin TM. Prevalence of RHD 1227A and hybrid Rhesus box in the general Chinese population. Transl Kes 2007; 149: 31-36.
26. Wagner T, Körmöczi GF, Buchta C, Vadon M, Lanzer G, Mayr WR, et al. Anti-D immunization by DEL red blood cells. Transfusion 2005; 45: 520-526.
27. Yasuda H, Ohto H, Sakuma S, Ishikawa Y. Secondary anti-D immunization by Del red blood cells. Transfusion 2005; 45: 1581-1584.
28. Kim KH, Kim KE, Woo KS, Han JY, Kim JM, Park KU. Primary anti-D immunization by DEL red blood cells. Korean J Lab Med 2009; 29: 361-365.
29. Shao CP. Transfusion of RhD-positive blood in "Asia type" DEL recipients. N Engl J Med 2010; 362: 472-473.
30. Körmöczi GF, Gassner C, Shao CP, Uchikawa M, Legler TJ. A comprehensive analysis of DEL types: partial DEL individuals are prone to anti-D alloimmunization. Transfusion 2005; 45: 1561-1567.
31. Kim JY, Kim SY, Kim CA, Yon GS, Park SS. Molecular characterization of D-Korean persons: development of a diagnostic strategy. Transfusion 2005; 45: 345-352.
32. Luettringhaus TA, Cho D, Ryang DW, Flegel WA. An easy RHD genotyping strategy for D-East Asian persons applied to Korean blood donors. Transfusion 2006; 46: 2128-2137.
33. Richard M, Perreault J, Constanzo-Yanez J, Khalifé S, St-Louis M. A new DEL variant caused by exon 8 deletion. Transfusion 2007; 47: 852-857.