Molecular background of Rh D-positive, D-negative, Del and weak D phenotypes in Chinese

Vox Sanguinis

Volumn 83, Issue 2, 2002, Pages 156-161

  Shao, C P ^a   Maas, J H ^a   Su, Y Q ^b   Kohler M ^a   Legler, Tobias J ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b Shenzhen Institute of Transfusion Medicine   (China)

Author keywords

Chinese; Del; Genotype; Phenotype; RhD

Indexed keywords

RHESUS D ANTIGEN;

ALLELISM; ARTICLE; CHINESE; CONTROLLED STUDY; DNA DETERMINATION; ETHNIC DIFFERENCE; FEMALE; GENE; GENETIC ANALYSIS; GENOTYPE; HETEROZYGOTE DETECTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; RHD GENE; SEQUENCE ANALYSIS;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; DNA PRIMERS; GENE FREQUENCY; GENOTYPE; HUMANS; PHENOTYPE; POLYMERASE CHAIN REACTION; RH-HR BLOOD-GROUP SYSTEM; SENSITIVITY AND SPECIFICITY;

EID: 0012514010     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1423-0410.2002.00192.x     Document Type: Article

References (23)

1. Wagner FF, Flegel WA: RHD gene deletion occurred in the Rhesus box. Blood 2000; 95:3662-3668
2. Wagner FF, Frohmajer A, Flegel WA: RHD positive haplotypes in D negative Europeans. BMC Genet 2001; 2:10
3. Faas BH, Beckers EA, Simsek S, Overbeeke MA, Pepper R, van Rhenen DJ, dem Borne AE, van der Schoot CE: Involvement of Ser103 of the Rh polypeptides in G epitope formation. Transfusion 1996; 36:506-511
4. Huang CH: Alteration of RH gene structure and expression in human dCCee and DCW-red blood cells: phenotypic homozygosity versus genotypic heterozygosity. Blood 1996; 88:2326-2333
5. Okuda H, Kawano M, Iwamoto S, Tanaka M, Seno T, Okubo Y, Kajii E: The RHD gene is highly detectable in RhD-negative Japanese donors. J Clin Invest 1997; 100:373-379
6. u), and partial D phenotypes, as determined by multiplex polymerase chain reaction analysis of the RHD gene. Blood 1997; 89:2568-2577
7. Andrews KT, Wolter LC, Saul A, Hyland CA: The RhD-trait in a white patient with the RhCCee phenotype attributed to a four-nucleotide deletion in the RHD gene [letter]. Blood 1998; 92:1839-1840
8. Singleton BK, Green CA, Avent ND, Martin PG, Smart E, Daka A, Narter-Olaga EG, Hawthorne LM, Daniels G: The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in Africans with the Rh D-negative blood group phenotype. Blood 2000; 95:12-18
9. Lan JC, Chen Q, Wu DL, Ding H, Pong DB, Zhao T: Genetic polymorphism of RhD-negative associated haplotypes in the Chinese. J Hum Genet 2000; 45:224-227
10. Sun CF, Chou CS, Lai NC, Wang WT: RHD gene polymorphisms among RhD-negative Chinese in Taiwan. Vox Sang 1998; 75:52-57
11. Mak KH, Yan KF, Cheng SS, Yuen MY: Rh phenotypes of Chinese blood donors in Hong Kong, with special reference to weak D antigens. Transfusion 1993; 33:348-351
12. el is caused by a deletion of 1013 bp between introns 8 and 9 including exon 9 of RHD gene [letter]. Blood 1998; 92:2602-2604
13. Vengelen-Tyler V: Technical Manual, edn 12. Bethesda, MD, American Association of Blood Banks, 1996
14. Legler TJ, Maas JH, Köhler M, Wagner T, Daniels GL, Perco P, Panzer S: RHD sequencing. A new tool for decision making on transfusion therapy and provision of Rh prophylaxis. Transfus Med 2001; 11:383-388
15. Legler TJ, Eber SW, Lakomek M, Lynen R, Maas JH, Pekrun A, Repas-Humpe M, Schroter W, Köhler M: Application of RHD and RHCE genotyping for correct blood group determination in chronically transfused patients. Transfusion 1999; 39:852-855
16. Poulter M, Kemp TJ, Carritt B: DNA-based Rhesus typing: simultaneous determination of RHC and RHD status using the polymerase chain reaction. Vox Sang 1996; 70:164-168
17. Legler TJ, Maas JH, Blaschke V, Malekan M, Ohto H, Lynen R, Bustami N, Schwartz DW, Mayr WR, Köhler M, Panzer S: RHD genotyping in weak D phenotypes by multiple polymerase chain reactions. Transfusion 1998; 38:434-440
18. Wagner FF, Gassner C, Müller TH, Schonitzer D, Schunter F, Flegel WA: Molecular basis of weak D phenotypes. Blood 1999; 93:385-393
19. Xu Q, Zhang S, Zhang J, Si G, Song Y, Wang M, Li J, Wang W, Nie X: Study on polymorphism of D gene exons among RhD-negative Chinese Han population [Chinese]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2001; 18:39-42
20. Fukumori Y, Hori Y, Ohnoki S, Minami A, Okubo Y, Daniels GL: Further analysis of Del (D-elute) using polymerase chain reaction (PCR) with RHD gene-specific primers. Transfus Med 1997; 7:227-231
21. el Phenotype [Abstract]. Transfus Clin Biol 2001; 8:9s
22. Aubin JT, Le Van Kim C, Mouro I, Colin Y, Bignozzi C, Brossard Y, Cartron JP: Specificity and sensitivity of RHD genotyping methods by PCR-based DNA amplification. Br J Haematol 1997; 98:356-364
23. Avent ND: Antenatal genotyping of the blood groups of the fetus [Review]. Vox Sang 1998; 74:365-374