Genetics of familial atrial fibrillation

Europace

Volumn 11, Issue 10, 2009, Pages 1267-1271

  Campuzano, Oscar ^a   Brugada, Ramon ^a  

^a UNIVERSITY OF GIRONA   (Spain)

Author keywords

Atrial fibrillation; Genetics

Indexed keywords

AUTOSOMAL DOMINANT INHERITANCE; AUTOSOMAL RECESSIVE INHERITANCE; CHROMOSOME 10Q; FAMILIAL DISEASE; GENE LOCUS; GENETIC PREDISPOSITION; GENOME ANALYSIS; HEART ATRIUM FIBRILLATION; HUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; REVIEW; SODIUM CURRENT; SOMATIC MUTATION;

ATRIAL FIBRILLATION; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HUMANS; INCIDENCE; MODELS, GENETIC; POTASSIUM CHANNELS;

EID: 70349483986     PISSN: 10995129     EISSN: 15322092     Source Type: Journal    
DOI: 10.1093/europace/eup199     Document Type: Review

References (44)

1. Feinberg WM, Blackshear JL, Laupacis A, Kronmal R, Hart RG. Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications. Arch Intern Med 1995;155:469-473
2. Wolf PA, Singer DE. Preventing stroke in atrial fibrillation. Am Fam Physician 1997; 56 :2242-2250
3. Barth AS, Hare JM. The potential for the transcriptome to serve as a clinical bio-marker for cardiovascular diseases. Circ Res 2006;98:1459-1461
4. Barth AS, Merk S, Arnoldi E, Zwermann L, Kloos P, Gebauer M et al. Reprogramming of the human atrial transcriptome in permanent atrial fibrillation: expression of a ventricular-like genomic signature. Circ Res 2005;96:1022-1029
5. Brugada R. Molecular biology of atrial fibrillation. Minerva Cardioangiol 2004;52: 65-72.
6. Wolff L. Familiar auricular fibrillation. New Engl J Med 1943;229:396.
7. Darbar D, Herron KJ, Ballew JD, Jahangir A, Gersh BJ, Shen WK et al. Familial atrial fibrillation is a genetically heterogeneous disorder. J Am Coll Cardiol 2003; 41 :2185-2192
8. Arnar DO, Thorvaldsson S, Manolio TA, Thorgeirsson G, Kristjansson K, Hakonarson H et al. Familial aggregation of atrial fibrillation in Iceland. Eur Heart J 2006;27:708-712
9. Fox CS, Parise H, D'Agostino RB Sr, Lloyd-Jones DM, Vasan RS, Wang TJ et al. Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring. J Am Med Assoc 2004;291:2851-2855
10. Brugada R, Tapscott T, Czernuszewicz GZ, Marian AJ, Iglesias A, Mont L et al. Identification of a genetic locus for familial atrial fibrillation. N Engl J Med 1997; 336:905-911
11. Ellinor PT, Shin JT, Moore RK, Yoerger DM, MacRae CA. Locus for atrial fibrilla-tion maps to chromosome 6q14-16. Circulation 2003;107:2880-2883
12. Chen YH, Xu SJ, Bendahhou S, Wang XL, Wang Y, Xu WY et al. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 2003;299:251-254
13. Hong K, Piper DR, Diaz-Valdecantos A, Brugada J, Oliva A, Burashnikov E et al. De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero. Cardiovasc Res 2005;68:433-440 (Pubitemid 41566563)
14. Otway R, Vandenberg JI, Guo G, Varghese A, Castro ML, Liu J et al. Stretch-sensitive KCNQ1 mutation A link between genetic and environmental factors in the pathogenesis of atrial fibrillation? J Am Coll Cardiol 2007;49:578-586
15. Yang Y, Xia M, Jin Q, Bendahhou S, Shi J, Chen Y et al. Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation. Am J Hum Genet 2004;75:899-905.
16. Zhang DF, Liang B, Lin J, Liu B, Zhou QS, Yang YQ. KCNE3 R53H substitution in familial atrial fibrillation. Chin Med J (Engl) 2005;118:1735-1738
17. Xia M, Jin Q, Bendahhou S, He Y, Larroque MM, Chen Y et al. A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation. Biochem Biophys Res Commun 2005;332:1012-1019
18. Olson TM, Alekseev AE, Liu XK, Park S, Zingman LV, Bienengraeber M et al. Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation. Hum Mol Genet 2006;15:2185-2191
19. Viswanathan PC, Balser JR. Inherited sodium channelopathies: a continuum of channel dysfunction. Trends Cardiovasc Med 2004;14:28-35.
20. Darbar D, Kannankeril PJ, Donahue BS, Kucera G, Stubblefield T, Haines JL et al. Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation. Circulation 2008;117:1927-1935.
21. Benito B, Brugada R, Perich RM, Lizotte E, Cinca J, Mont L et al. A mutation in the sodium channel is responsible for the association of long QT syndrome and familial atrial fibrillation. Heart Rhythm 2008;5:1434-1440
22. Hodgson-Zingman DM, Karst ML, Zingman LV, Heublein DM, Darbar D, Herron KJ et al. Atrial natriuretic peptide frameshift mutation in familial atrial fibrillation. N Engl J Med 2008;359:158-165
23. Zhang X, Chen S, Yoo S, Chakrabarti S, Zhang T, Ke T et al. Mutation in nuclear pore component NUP155 leads to atrial fibrillation and early sudden cardiac death. Cell 2008;135:1017-1027
24. Gollob MH, Jones DL, Krahn AD, Danis L, Gong XQ, Shao Q et al. Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation. N Engl J Med 2006;354:2677-2688
25. Gruver EJ, Fatkin D, Dodds GA, Kisslo J, Maron BJ, Seidman JG et al. Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation. Am J Cardiol 1999;83:13H-18H.
26. Ohkubo R, Nakagawa M, Higuchi I, Utatsu Y, Miyazato H, Atsuchi Y et al. Familial skeletal myopathy with atrioventricular block. Intern Med 1999;38:856-860
27. Gillmore JD, Booth DR, Pepys MB, Hawkins PN. Hereditary cardiac amyloidosis associated with the transthyretin Ile122 mutation in a white man. Heart 1999;82:e2.
28. Benito B, Brugada R, Perich RM, Lizotte E, Cinca J, Mont L et al. A mutation in the sodium channel is responsible for the association of long QT syndrome and familial atrial fibrillation. Heart Rhythm 2008;5:1434-1440
29. Schott JJ, Charpentier F, Peltier S, Foley P, Drouin E, Bouhour JB et al. Mapping of a gene for long QT syndrome to chromosome 4q25-27. Am J Hum Genet 1995; 57 :1114-1122
30. Morita H, Kusano-Fukushima K, Nagase S, Fujimoto Y, Hisamatsu K, Fujio H et al. Atrial fibrillation and atrial vulnerability in patients with Brugada syndrome. J Am Coll Cardiol 2002;40:1437-1444
31. Brugada R, Hong K, Dumaine R, Cordeiro J, Gaita F, Borggrefe M et al. Sudden death associated with short-QT syndrome linked to mutations in HERG. Circulation 2004;109:30-35
32. Hong K, Bjerregaard P, Gussak I, Brugada R. Short QT syndrome and atrial fibrilla-tion caused by mutation in KCNH2. J Cardiovasc Electrophysiol 2005;16:394-396
33. Gussak I, Brugada P, Brugada J, Wright RS, Kopecky SL, Chaitman BR et al. Idiopathic short QT interval: a new clinical syndrome? Cardiology 2000;94:99-102.
34. Darbar D, Hardy A, Haines JL, Roden DM. Prolonged signal-averaged P-wave duration as an intermediate phenotype for familial atrial fibrillation. J Am Coll Cardiol 2008;51:1083-1089
35. Yamashita T, Hayami N, Ajiki K, Oikawa N, Sezaki K, Inoue M et al. Is ACE gene polymorphism associated with lone atrial fibrillation? Jpn Heart J 1997;38:637-641
36. Nakai K, Itoh C, Miura Y, Hotta K, Musha T, Itoh T et al. Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with serum ACE concentration and increased risk for CAD in the Japanese. Circulation 1994;90: 2199-2202
37. Tsai CT, Lai LP, Lin JL, Chiang FT, Hwang JJ, Ritchie MD et al. Renin-angiotensin system gene polymorphisms and atrial fibrillation. Circulation 2004;109:1640-1646
38. Ehrlich JR, Zicha S, Coutu P, Hebert TE, Nattel S. Atrial fibrillation-associated minK38G/S polymorphism modulates delayed rectifier current and membrane localization. Cardiovasc Res 2005;67:520-528
39. Lai LP, Lin JL, Huang SK. Molecular genetic studies in atrial fibrillation. Cardiology 2003;100:109-113
40. Chen LY, Herron KJ, Tai BC, Olson TM. Lone atrial fibrillation: influence of familial disease on gender predilection. J Cardiovasc Electrophysiol 2008;19:802-806
41. Gaudino M, Andreotti F, Zamparelli R, Di Castelnuovo A, Nasso G, Burzotta F et al. The -174G/C interleukin-6 polymorphism influences postoperative interleukin-6 levels and postoperative atrial fibrillation. Is atrial fibrillation an inflammatory complication? Circulation 2003;108:II195-99.
42. Splawski I, Tristani-Firouzi M, Lehmann MH, Sanguinetti MC, Keating MT. Mutations in the hminK gene cause long QT syndrome and suppress IKs function. Nat Genet 1997;17:338-340
43. Gudbjartsson DF, Arnar DO, Helgadottir A, Gretarsdottir S, Holm H, Sigurdsson A et al. Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature 2007;448:353-357
44. Kaab S, Darbar D, van Noord C, Dupuis J, Pfeufer A, Newton-Cheh C et al. Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. Eur Heart J 2009;30:813-819