-
1
-
-
0347753697
-
Peroxisome-proliferator-activated receptors and cancers: complex stories
-
Michalik L, Desvergne B, Wahli W, (2004) Peroxisome-proliferator-activated receptors and cancers: complex stories. Nat Rev Cancer 4: 61-70.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 61-70
-
-
Michalik, L.1
Desvergne, B.2
Wahli, W.3
-
2
-
-
0034700110
-
Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer
-
Gupta RA, Tan J, Krause WF, Geraci MW, Willson TM, et al. (2000) Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer. Proc Natl Acad Sci U S A 97: 13275-13280.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13275-13280
-
-
Gupta, R.A.1
Tan, J.2
Krause, W.F.3
Geraci, M.W.4
Willson, T.M.5
-
3
-
-
0033615352
-
PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
-
He TC, Chan TA, Vogelstein B, Kinzler KW, (1999) PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99: 335-345.
-
(1999)
Cell
, vol.99
, pp. 335-345
-
-
He, T.C.1
Chan, T.A.2
Vogelstein, B.3
Kinzler, K.W.4
-
4
-
-
2342640982
-
Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines
-
Stephen RL, Gustafsson MC, Jarvis M, Tatoud R, Marshall BR, et al. (2004) Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines. Cancer Res 64: 3162-3170.
-
(2004)
Cancer Res
, vol.64
, pp. 3162-3170
-
-
Stephen, R.L.1
Gustafsson, M.C.2
Jarvis, M.3
Tatoud, R.4
Marshall, B.R.5
-
5
-
-
1942470331
-
Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth
-
Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, et al. (2004) Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nat Med 10: 245-247.
-
(2004)
Nat Med
, vol.10
, pp. 245-247
-
-
Gupta, R.A.1
Wang, D.2
Katkuri, S.3
Wang, H.4
Dey, S.K.5
-
6
-
-
4544320012
-
Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta
-
Wang D, Wang H, Shi Q, Katkuri S, Walhi W, et al. (2004) Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell 6: 285-295.
-
(2004)
Cancer Cell
, vol.6
, pp. 285-295
-
-
Wang, D.1
Wang, H.2
Shi, Q.3
Katkuri, S.4
Walhi, W.5
-
7
-
-
18144384743
-
Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis
-
Yin Y, Russell RG, Dettin LE, Bai R, Wei ZL, et al. (2005) Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis. Cancer Res 65: 3950-3957.
-
(2005)
Cancer Res
, vol.65
, pp. 3950-3957
-
-
Yin, Y.1
Russell, R.G.2
Dettin, L.E.3
Bai, R.4
Wei, Z.L.5
-
8
-
-
0035956850
-
Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells
-
Park BH, Vogelstein B, Kinzler KW, (2001) Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Proc Natl Acad Sci U S A 98: 2598-2603.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2598-2603
-
-
Park, B.H.1
Vogelstein, B.2
Kinzler, K.W.3
-
9
-
-
84857641358
-
The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention
-
Peters JM, Shah YM, Gonzalez FJ, (2012) The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention. Nat Rev Cancer 12: 181-195.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 181-195
-
-
Peters, J.M.1
Shah, Y.M.2
Gonzalez, F.J.3
-
10
-
-
0037039374
-
Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer
-
Barak Y, Liao D, He W, Ong ES, Nelson MC, et al. (2002) Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci U S A 99: 303-308.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 303-308
-
-
Barak, Y.1
Liao, D.2
He, W.3
Ong, E.S.4
Nelson, M.C.5
-
11
-
-
2442708845
-
Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis
-
Harman FS, Nicol CJ, Marin HE, Ward JM, Gonzalez FJ, et al. (2004) Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis. Nat Med 10: 481-483.
-
(2004)
Nat Med
, vol.10
, pp. 481-483
-
-
Harman, F.S.1
Nicol, C.J.2
Marin, H.E.3
Ward, J.M.4
Gonzalez, F.J.5
-
12
-
-
10644231009
-
PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine
-
Reed KR, Sansom OJ, Hayes AJ, Gescher AJ, Winton DJ, et al. (2004) PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine. Oncogene 23: 8992-8996.
-
(2004)
Oncogene
, vol.23
, pp. 8992-8996
-
-
Reed, K.R.1
Sansom, O.J.2
Hayes, A.J.3
Gescher, A.J.4
Winton, D.J.5
-
13
-
-
34249696521
-
Block of nuclear receptor ubiquitination. A mechanism of ligand-dependent control of peroxisome proliferator-activated receptor delta activity
-
Genini D, Catapano CV, (2007) Block of nuclear receptor ubiquitination. A mechanism of ligand-dependent control of peroxisome proliferator-activated receptor delta activity. J Biol Chem 282: 11776-11785.
-
(2007)
J Biol Chem
, vol.282
, pp. 11776-11785
-
-
Genini, D.1
Catapano, C.V.2
-
14
-
-
45749154831
-
Multiple Interactions between Peroxisome Proliferators-Activated Receptors and the Ubiquitin-Proteasome System and Implications for Cancer Pathogenesis
-
Genini D, Carbone GM, Catapano CV, (2008) Multiple Interactions between Peroxisome Proliferators-Activated Receptors and the Ubiquitin-Proteasome System and Implications for Cancer Pathogenesis. PPAR Res 2008: 195065.
-
(2008)
PPAR Res
, vol.2008
, pp. 195065
-
-
Genini, D.1
Carbone, G.M.2
Catapano, C.V.3
-
15
-
-
0035496616
-
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
-
Gupta RA, Dubois RN, (2001) Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat Rev Cancer 1: 11-21.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 11-21
-
-
Gupta, R.A.1
Dubois, R.N.2
-
16
-
-
0037652234
-
Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors
-
Ermert L, Dierkes C, Ermert M, (2003) Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors. Clin Cancer Res 9: 1604-1610.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1604-1610
-
-
Ermert, L.1
Dierkes, C.2
Ermert, M.3
-
17
-
-
0037189578
-
Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator-activated receptors in bladder cancer cells
-
Fauconnet S, Lascombe I, Chabannes E, Adessi GL, Desvergne B, et al. (2002) Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator-activated receptors in bladder cancer cells. J Biol Chem 277: 23534-23543.
-
(2002)
J Biol Chem
, vol.277
, pp. 23534-23543
-
-
Fauconnet, S.1
Lascombe, I.2
Chabannes, E.3
Adessi, G.L.4
Desvergne, B.5
-
18
-
-
34047243022
-
Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression
-
Wang D, Wang H, Guo Y, Ning W, Katkuri S, et al. (2006) Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression. Proc Natl Acad Sci U S A 103: 19069-19074.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 19069-19074
-
-
Wang, D.1
Wang, H.2
Guo, Y.3
Ning, W.4
Katkuri, S.5
-
19
-
-
34948817275
-
New molecularly targeted therapies for lung cancer
-
Sun S, Schiller JH, Spinola M, Minna JD, (2007) New molecularly targeted therapies for lung cancer. J Clin Invest 117: 2740-2750.
-
(2007)
J Clin Invest
, vol.117
, pp. 2740-2750
-
-
Sun, S.1
Schiller, J.H.2
Spinola, M.3
Minna, J.D.4
-
20
-
-
33749833663
-
Cellular and molecular consequences of peroxisome proliferator-activated receptor-gamma activation in ovarian cancer cells
-
Vignati S, Albertini V, Rinaldi A, Kwee I, Riva C, et al. (2006) Cellular and molecular consequences of peroxisome proliferator-activated receptor-gamma activation in ovarian cancer cells. Neoplasia 8: 851-861.
-
(2006)
Neoplasia
, vol.8
, pp. 851-861
-
-
Vignati, S.1
Albertini, V.2
Rinaldi, A.3
Kwee, I.4
Riva, C.5
-
21
-
-
67649537602
-
Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells
-
Napoli S, Pastori C, Magistri M, Carbone GM, Catapano CV, (2009) Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells. EMBO J 28: 1708-1719.
-
(2009)
EMBO J
, vol.28
, pp. 1708-1719
-
-
Napoli, S.1
Pastori, C.2
Magistri, M.3
Carbone, G.M.4
Catapano, C.V.5
-
22
-
-
56049083203
-
Peroxisome proliferator-activated receptor beta/delta expression and activation in lung cancer
-
Pedchenko TV, Gonzalez AL, Wang D, DuBois RN, Massion PP, (2008) Peroxisome proliferator-activated receptor beta/delta expression and activation in lung cancer. Am J Respir Cell Mol Biol 39: 689-696.
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 689-696
-
-
Pedchenko, T.V.1
Gonzalez, A.L.2
Wang, D.3
DuBois, R.N.4
Massion, P.P.5
-
23
-
-
83855160814
-
Dissecting the role of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in colon, breast, and lung carcinogenesis
-
Peters JM, Foreman JE, Gonzalez FJ, (2011) Dissecting the role of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in colon, breast, and lung carcinogenesis. Cancer Metastasis Rev 30: 619-640.
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 619-640
-
-
Peters, J.M.1
Foreman, J.E.2
Gonzalez, F.J.3
-
24
-
-
0036771764
-
Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway
-
Di-Poi N, Tan NS, Michalik L, Wahli W, Desvergne B, (2002) Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway. Mol Cell 10: 721-733.
-
(2002)
Mol Cell
, vol.10
, pp. 721-733
-
-
Di-Poi, N.1
Tan, N.S.2
Michalik, L.3
Wahli, W.4
Desvergne, B.5
-
25
-
-
34547891037
-
Transcriptional network governing the angiogenic switch in human pancreatic cancer
-
Abdollahi A, Schwager C, Kleeff J, Esposito I, Domhan S, et al. (2007) Transcriptional network governing the angiogenic switch in human pancreatic cancer. Proc Natl Acad Sci U S A 104: 12890-12895.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12890-12895
-
-
Abdollahi, A.1
Schwager, C.2
Kleeff, J.3
Esposito, I.4
Domhan, S.5
-
26
-
-
33244482536
-
Combinatorial roles of nuclear receptors in inflammation and immunity
-
Glass CK, Ogawa S, (2006) Combinatorial roles of nuclear receptors in inflammation and immunity. Nat Rev Immunol 6: 44-55.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 44-55
-
-
Glass, C.K.1
Ogawa, S.2
-
27
-
-
38749152401
-
Identification and Characterization of a Selective Peroxisome Proliferator-Activated Receptor {beta}/{delta} (NR1C2) Antagonist
-
Shearer BG, Steger DJ, Way JM, Stanley TB, Lobe DC, et al. (2008) Identification and Characterization of a Selective Peroxisome Proliferator-Activated Receptor {beta}/{delta} (NR1C2) Antagonist. Mol Endocrinol 22: 523-529.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 523-529
-
-
Shearer, B.G.1
Steger, D.J.2
Way, J.M.3
Stanley, T.B.4
Lobe, D.C.5
-
28
-
-
33644609473
-
PPAR gamma represses VEGF expression in human endometrial cells: implications for uterine angiogenesis
-
Peeters LL, Vigne JL, Tee MK, Zhao D, Waite LL, et al. (2005) PPAR gamma represses VEGF expression in human endometrial cells: implications for uterine angiogenesis. Angiogenesis 8: 373-379.
-
(2005)
Angiogenesis
, vol.8
, pp. 373-379
-
-
Peeters, L.L.1
Vigne, J.L.2
Tee, M.K.3
Zhao, D.4
Waite, L.L.5
-
29
-
-
67749122122
-
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
-
Engelman JA, (2009) Targeting PI3K signalling in cancer: opportunities, challenges and limitations. Nat Rev Cancer 9: 550-562.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 550-562
-
-
Engelman, J.A.1
-
30
-
-
52149086346
-
Peroxisome proliferator-activated receptor-delta agonist enhances vasculogenesis by regulating endothelial progenitor cells through genomic and nongenomic activations of the phosphatidylinositol 3-kinase/Akt pathway
-
Han JK, Lee HS, Yang HM, Hur J, Jun SI, et al. (2008) Peroxisome proliferator-activated receptor-delta agonist enhances vasculogenesis by regulating endothelial progenitor cells through genomic and nongenomic activations of the phosphatidylinositol 3-kinase/Akt pathway. Circulation 118: 1021-1033.
-
(2008)
Circulation
, vol.118
, pp. 1021-1033
-
-
Han, J.K.1
Lee, H.S.2
Yang, H.M.3
Hur, J.4
Jun, S.I.5
-
31
-
-
48949119347
-
PPARbeta/delta agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3K and NF-kappaB signals
-
Han S, Ritzenthaler JD, Zheng Y, Roman J, (2008) PPARbeta/delta agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3K and NF-kappaB signals. Am J Physiol Lung Cell Mol Physiol 294: L1238-1249.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Han, S.1
Ritzenthaler, J.D.2
Zheng, Y.3
Roman, J.4
-
32
-
-
40849140987
-
Antitumorigenic effects of peroxisome proliferator-activated receptor-gamma in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via inhibition of nuclear factor-kappaB
-
Bren-Mattison Y, Meyer AM, Van Putten V, Li H, Kuhn K, et al. (2008) Antitumorigenic effects of peroxisome proliferator-activated receptor-gamma in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via inhibition of nuclear factor-kappaB. Mol Pharmacol 73: 709-717.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 709-717
-
-
Bren-Mattison, Y.1
Meyer, A.M.2
Van Putten, V.3
Li, H.4
Kuhn, K.5
-
33
-
-
61549114992
-
Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha
-
Han S, Ritzenthaler JD, Sun X, Zheng Y, Roman J, (2009) Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha. Am J Respir Cell Mol Biol 40: 325-331.
-
(2009)
Am J Respir Cell Mol Biol
, vol.40
, pp. 325-331
-
-
Han, S.1
Ritzenthaler, J.D.2
Sun, X.3
Zheng, Y.4
Roman, J.5
-
34
-
-
34249087361
-
Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors
-
Schug TT, Berry DC, Shaw NS, Travis SN, Noy N, (2007) Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. Cell 129: 723-733.
-
(2007)
Cell
, vol.129
, pp. 723-733
-
-
Schug, T.T.1
Berry, D.C.2
Shaw, N.S.3
Travis, S.N.4
Noy, N.5
-
35
-
-
0042388005
-
PPARdelta activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells
-
Glinghammar B, Skogsberg J, Hamsten A, Ehrenborg E, (2003) PPARdelta activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells. Biochem Biophys Res Commun 308: 361-368.
-
(2003)
Biochem Biophys Res Commun
, vol.308
, pp. 361-368
-
-
Glinghammar, B.1
Skogsberg, J.2
Hamsten, A.3
Ehrenborg, E.4
-
36
-
-
79955632705
-
The expression of both peroxisome proliferator-activated receptor delta and cyclooxygenase-2 in tissues is associated with poor prognosis in colorectal cancer patients
-
Yoshinaga M, Taki K, Somada S, Sakiyama Y, Kubo N, et al. (2011) The expression of both peroxisome proliferator-activated receptor delta and cyclooxygenase-2 in tissues is associated with poor prognosis in colorectal cancer patients. Dig Dis Sci 56: 1194-1200.
-
(2011)
Dig Dis Sci
, vol.56
, pp. 1194-1200
-
-
Yoshinaga, M.1
Taki, K.2
Somada, S.3
Sakiyama, Y.4
Kubo, N.5
-
37
-
-
0034727094
-
Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
-
Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW, et al. (2000) Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407: 538-541.
-
(2000)
Nature
, vol.407
, pp. 538-541
-
-
Simoncini, T.1
Hafezi-Moghadam, A.2
Brazil, D.P.3
Ley, K.4
Chin, W.W.5
-
38
-
-
0242290354
-
Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85alpha, androgen receptor, and Src
-
Sun M, Yang L, Feldman RI, Sun XM, Bhalla KN, et al. (2003) Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85alpha, androgen receptor, and Src. J Biol Chem 278: 42992-43000.
-
(2003)
J Biol Chem
, vol.278
, pp. 42992-43000
-
-
Sun, M.1
Yang, L.2
Feldman, R.I.3
Sun, X.M.4
Bhalla, K.N.5
-
39
-
-
77953283014
-
NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling
-
Zhou H, Liu W, Su Y, Wei Z, Liu J, et al. (2010) NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling. Cancer Cell 17: 560-573.
-
(2010)
Cancer Cell
, vol.17
, pp. 560-573
-
-
Zhou, H.1
Liu, W.2
Su, Y.3
Wei, Z.4
Liu, J.5
-
40
-
-
33646107369
-
VEGF receptor signalling - in control of vascular function
-
Olsson AK, Dimberg A, Kreuger J, Claesson-Welsh L, (2006) VEGF receptor signalling- in control of vascular function. Nat Rev Mol Cell Biol 7: 359-371.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 359-371
-
-
Olsson, A.K.1
Dimberg, A.2
Kreuger, J.3
Claesson-Welsh, L.4
-
41
-
-
4143070427
-
Pulmonary prostacyclin synthase overexpression chemoprevents tobacco smoke lung carcinogenesis in mice
-
Keith RL, Miller YE, Hudish TM, Girod CE, Sotto-Santiago S, et al. (2004) Pulmonary prostacyclin synthase overexpression chemoprevents tobacco smoke lung carcinogenesis in mice. Cancer Res 64: 5897-5904.
-
(2004)
Cancer Res
, vol.64
, pp. 5897-5904
-
-
Keith, R.L.1
Miller, Y.E.2
Hudish, T.M.3
Girod, C.E.4
Sotto-Santiago, S.5
-
42
-
-
57249089708
-
Prostacyclin prevents murine lung cancer independent of the membrane receptor by activation of peroxisomal proliferator-activated receptor gamma
-
Nemenoff R, Meyer AM, Hudish TM, Mozer AB, Snee A, et al. (2008) Prostacyclin prevents murine lung cancer independent of the membrane receptor by activation of peroxisomal proliferator-activated receptor gamma. Cancer Prev Res (Phila) 1: 349-356.
-
(2008)
Cancer Prev Res (Phila)
, vol.1
, pp. 349-356
-
-
Nemenoff, R.1
Meyer, A.M.2
Hudish, T.M.3
Mozer, A.B.4
Snee, A.5
|