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Volumn 61, Issue 10, 2012, Pages 2585-2591

GLP-1 receptor antagonist exendin-(9-39) elevates fasting blood glucose levels in congenital hyperinsulinism owing to inactivating mutations in the ATP-sensitive K+ channel

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; AMINO ACID; EXENDIN 9 39; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCOSE; HORMONE RECEPTOR BLOCKING AGENT; INSULIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; UNCLASSIFIED DRUG;

EID: 84866607794     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0166     Document Type: Article
Times cited : (87)

References (30)
  • 1
    • 0036833473 scopus 로고    scopus 로고
    • Editorial: Advances in diagnosis and treatment of hyperinsulinism in infants and children
    • DOI 10.1210/jc.2002-021403
    • Stanley CA. Advances in diagnosis and treatment of hyperinsulinism in infants and children. J Clin Endocrinol Metab 2002;87:4857-4859 (Pubitemid 35316315)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.11 , pp. 4857-4859
    • Stanley, C.A.1
  • 2
    • 84859089485 scopus 로고    scopus 로고
    • Glucose metabolism in 105 children and adolescents after pancreatectomy for congenital hyperinsulinism
    • Beltrand J, Caquard M, Arnoux JB, et al. Glucose metabolism in 105 children and adolescents after pancreatectomy for congenital hyperinsulinism. Diabetes Care 2012;35:198-203
    • (2012) Diabetes Care , vol.35 , pp. 198-203
    • Beltrand, J.1    Caquard, M.2    Arnoux, J.B.3
  • 3
    • 67049155251 scopus 로고    scopus 로고
    • Unraveling the science of incretin biology
    • Nauck MA. Unraveling the science of incretin biology. Am J Med 2009;122 (Suppl.):S3-S10
    • (2009) Am J Med , vol.122 , Issue.SUPPL.
    • Nauck, M.A.1
  • 5
    • 0032960834 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: Studies with the antagonist exendin 9-39
    • DOI 10.2337/diabetes.48.1.86
    • Edwards CM, Todd JF, Mahmoudi M, et al. Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: studies with the antagonist exendin 9-39. Diabetes 1999;48:86-93 (Pubitemid 29019356)
    • (1999) Diabetes , vol.48 , Issue.1 , pp. 86-93
    • Edwards, C.M.B.1    Todd, J.F.2    Mahmoudi, M.3    Wang, Z.4    Wang, R.M.5    Ghatei, M.A.6    Bloom, S.R.7
  • 6
    • 30944467225 scopus 로고    scopus 로고
    • Endogenous glucagon-like peptide 1 controls endocrine pancreatic secretion and antro-pyloro-duodenal motility in humans
    • DOI 10.1136/gut.2004.059741
    • Schirra J, Nicolaus M, Roggel R, et al. Endogenous glucagon-like peptide 1 controls endocrine pancreatic secretion and antro-pyloro-duodenal motility in humans. Gut 2006;55:243-251 (Pubitemid 43117285)
    • (2006) Gut , vol.55 , Issue.2 , pp. 243-251
    • Schirra, J.1    Nicolaus, M.2    Roggel, R.3    Katschinski, M.4    Storr, M.5    Woerle, H.J.6    Goke, B.7
  • 7
    • 0037312829 scopus 로고    scopus 로고
    • Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy
    • DOI 10.2337/diabetes.52.2.365
    • De León DD, Deng S, Madani R, Ahima RS, Drucker DJ, Stoffers DA. Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy. Diabetes 2003;52:365-371 (Pubitemid 36173191)
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 365-371
    • De Leon, D.D.1    Deng, S.2    Madani, R.3    Ahima, R.S.4    Drucker, D.J.5    Stoffers, D.A.6
  • 8
    • 15044354104 scopus 로고    scopus 로고
    • GIP and GLP-1 as incretin hormones: Lessons from single and double incretin receptor knockout mice
    • DOI 10.1016/j.regpep.2004.07.019, Proceedings from the GLP1 Meeting on the Occasion of the 80th Birthday of Prof.Dr. Med. Dr. hc (em) Werner Creutzfeltdt.
    • Hansotia T, Drucker DJ. GIP and GLP-1 as incretin hormones: lessons from single and double incretin receptor knockout mice. Regul Pept 2005;128: 125-134 (Pubitemid 40380913)
    • (2005) Regulatory Peptides , vol.128 , Issue.2 , pp. 125-134
    • Hansotia, T.1    Drucker, D.J.2
  • 10
    • 78650860373 scopus 로고    scopus 로고
    • Endogenous GLP-1 regulates postprandial glycemia in humans: Relative contributions of insulin, glucagon, and gastric emptying
    • Nicolaus M, Brödl J, Linke R, Woerle HJ, Göke B, Schirra J. Endogenous GLP-1 regulates postprandial glycemia in humans: relative contributions of insulin, glucagon, and gastric emptying. J Clin Endocrinol Metab 2011;96:229-236
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 229-236
    • Nicolaus, M.1    Brödl, J.2    Linke, R.3    Woerle, H.J.4    Göke, B.5    Schirra, J.6
  • 11
    • 58149391357 scopus 로고    scopus 로고
    • Increased glucagon-like peptide-1 secretion and postprandial hypoglycemia in children after Nissen fundoplication
    • Palladino AA, Sayed S, Katz LE, Gallagher PR, De León DD. Increased glucagon-like peptide-1 secretion and postprandial hypoglycemia in children after Nissen fundoplication. J Clin Endocrinol Metab 2009;94:39-44
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 39-44
    • Palladino, A.A.1    Sayed, S.2    Katz, L.E.3    Gallagher, P.R.4    De León, D.D.5
  • 13
    • 54449098531 scopus 로고    scopus 로고
    • Exendin-(9-39) corrects fasting hypoglycemia in SUR-1-/- mice by lowering cAMP in pancreatic beta-cells and inhibiting insulin secretion
    • De León DD, Li C, Delson MI, Matschinsky FM, Stanley CA, Stoffers DA. Exendin-(9-39) corrects fasting hypoglycemia in SUR-1-/- mice by lowering cAMP in pancreatic beta-cells and inhibiting insulin secretion. J Biol Chem 2008;283:25786-25793
    • (2008) J Biol Chem , vol.283 , pp. 25786-25793
    • De León, D.D.1    Li, C.2    Delson, M.I.3    Matschinsky, F.M.4    Stanley, C.A.5    Stoffers, D.A.6
  • 15
    • 77958087153 scopus 로고    scopus 로고
    • Reactive hypoglycaemia following GLP-1 infusion in pancreas transplant recipients
    • Rickels MR, Naji A. Reactive hypoglycaemia following GLP-1 infusion in pancreas transplant recipients. Diabetes Obes Metab 2010;12:731-733
    • (2010) Diabetes Obes Metab , vol.12 , pp. 731-733
    • Rickels, M.R.1    Naji, A.2
  • 16
    • 0031721391 scopus 로고    scopus 로고
    • Exaggerated secretion of glucagon-like peptide- 1 (GLP-1) could cause reactive hypoglycaemia
    • DOI 10.1007/s001250051049
    • Toft-Nielsen M, Madsbad S, Holst JJ. Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia. Diabetologia 1998;41:1180-1186 (Pubitemid 28449084)
    • (1998) Diabetologia , vol.41 , Issue.10 , pp. 1180-1186
    • Toft-Nielsen, M.1    Madsbad, S.2    Holst, J.J.3
  • 17
    • 0037452225 scopus 로고    scopus 로고
    • A tumour that secretes glucagon-like peptide-1 and somatostatin in a patient with reactive hypoglycaemia and diabetes
    • DOI 10.1016/S0140-6736(03)12256-8
    • Todd JF, Stanley SA, Roufosse CA, et al. A tumour that secretes glucagon-like peptide-1 and somatostatin in a patient with reactive hypoglycaemia and diabetes. Lancet 2003;361:228-230 (Pubitemid 36126227)
    • (2003) Lancet , vol.361 , Issue.9353 , pp. 228-230
    • Todd, J.F.1    Stanley, S.A.2    Roufosse, C.A.3    Bishop, A.E.4    Khoo, B.5    Bloom, S.R.6    Meeran, K.7
  • 18
    • 17144371646 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
    • DOI 10.2337/diacare.28.5.1083
    • Kendall DM, Riddle MC, Rosenstock J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care 2005;28:1083-1091 (Pubitemid 40616617)
    • (2005) Diabetes Care , vol.28 , Issue.5 , pp. 1083-1091
    • Kendall, D.M.1    Riddle, M.C.2    Rosenstock, J.3    Zhuang, D.4    Kim, D.D.5    Fineman, M.S.6    Baron, A.D.7
  • 19
    • 0036724256 scopus 로고    scopus 로고
    • Glucose-sensing in glucagon-like peptide-1-secreting cells
    • Reimann F, Gribble FM. Glucose-sensing in glucagon-like peptide-1-secreting cells. Diabetes 2002;51:2757-2763 (Pubitemid 34970929)
    • (2002) Diabetes , vol.51 , Issue.9 , pp. 2757-2763
    • Reimann, F.1    Gribble, F.M.2
  • 20
    • 79961204682 scopus 로고    scopus 로고
    • Gastric bypass surgery enhances glucagon-like peptide 1-stimulated postprandial insulin secretion in humans
    • Salehi M, Prigeon RL, D'Alessio DA. Gastric bypass surgery enhances glucagon-like peptide 1-stimulated postprandial insulin secretion in humans. Diabetes 2011;60:2308-2314
    • (2011) Diabetes , vol.60 , pp. 2308-2314
    • Salehi, M.1    Prigeon, R.L.2    D'Alessio, D.A.3
  • 21
    • 0031789874 scopus 로고    scopus 로고
    • Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: Implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and β-cell glucose competence
    • DOI 10.1210/en.139.11.4448
    • Serre V, Dolci W, Schaerer E, et al. Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3′,5′-monophosphate levels and beta-cell glucose competence. Endocrinology 1998;139:4448-4454 (Pubitemid 28487758)
    • (1998) Endocrinology , vol.139 , Issue.11 , pp. 4448-4454
    • Serre, V.1    Dolci, W.2    Schaerer, E.3    Scrocchi, L.4    Drucker, D.5    Efrat, S.6    Thorens, B.7
  • 23
    • 0031965605 scopus 로고    scopus 로고
    • Dual glucagon recognition by pancreatic β-cells via glucagon and glucagon-like peptide 1 receptors
    • Moens K, Flamez D, Van Schravendijk C, Ling Z, Pipeleers D, Schuit F. Dual glucagon recognition by pancreatic beta-cells via glucagon and glucagon-like peptide 1 receptors. Diabetes 1998;47:66-72 (Pubitemid 28030809)
    • (1998) Diabetes , vol.47 , Issue.1 , pp. 66-72
    • Moens, K.1    Flamez, D.2    Van Schravendijk, C.3    Ling, Z.4    Pipeleers, D.5    Schuit, F.6
  • 24
    • 0028156856 scopus 로고
    • Effect of glucagon-like peptide-1 (proglucagon 78-107 amide) on hepatic glucose production in healthy man
    • DOI 10.1016/0026-0495(94)90164-3
    • Hvidberg A, Nielsen MT, Hilsted J, Orskov C, Holst JJ. Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man. Metabolism 1994;43:104-108 (Pubitemid 24047112)
    • (1994) Metabolism: Clinical and Experimental , vol.43 , Issue.1 , pp. 104-108
    • Hvidberg, A.1    Nielsen, M.T.2    Hilsted, J.3    Orskov, C.4    Holst, J.J.5
  • 26
    • 25844501587 scopus 로고    scopus 로고
    • Serum glucagon counterregulatory hormonal response to hypoglycemia is blunted in congenital hyperinsulinism
    • DOI 10.2337/diabetes.54.10.2946
    • Hussain K, Bryan J, Christesen HT, Brusgaard K, Aguilar-Bryan L. Serum glucagon counterregulatory hormonal response to hypoglycemia is blunted in congenital hyperinsulinism. Diabetes 2005;54:2946-2951 (Pubitemid 41401091)
    • (2005) Diabetes , vol.54 , Issue.10 , pp. 2946-2951
    • Hussain, K.1    Bryan, J.2    Christesen, H.T.3    Brusgaard, K.4    Aguilar-Bryan, L.5
  • 27
    • 9444266572 scopus 로고    scopus 로고
    • -/- mouse α-cells
    • DOI 10.2337/diabetes.53.suppl-3.S181
    • Gromada J, Ma X, Høy M, et al. ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells. Diabetes 2004;53(Suppl. 3):S181-S189 (Pubitemid 39564542)
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Gromada, J.1    Ma, X.2    Hoy, M.3    Bokvist, K.4    Salehi, A.5    Berggren, P.-O.6    Rorsmam, P.7
  • 29
    • 0027374336 scopus 로고
    • Short- and long-term use of octreotide in the treatment of congenital hyperinsulinism
    • Thornton PS, Alter CA, Katz LE, Baker L, Stanley CA. Short- and long-term use of octreotide in the treatment of congenital hyperinsulinism. J Pediatr 1993;123:637-643 (Pubitemid 23287542)
    • (1993) Journal of Pediatrics , vol.123 , Issue.4 , pp. 637-643
    • Thornton, P.S.1    Alter, C.A.2    Levitt, K.L.E.3    Baker, L.4    Stanley, C.A.5
  • 30
    • 77954452310 scopus 로고    scopus 로고
    • Necrotizing enterocolitis in neonates receiving octreotide for the management of congenital hyperinsulinism
    • Laje P, Halaby L, Adzick NS, Stanley CA. Necrotizing enterocolitis in neonates receiving octreotide for the management of congenital hyperinsulinism. Pediatr Diabetes 2010;11:142-147
    • (2010) Pediatr Diabetes , vol.11 , pp. 142-147
    • Laje, P.1    Halaby, L.2    Adzick, N.S.3    Stanley, C.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.