A tumour that secretes glucagon-like peptide-1 and somatostatin in a patient with reactive hypoglycaemia and diabetes

Lancet

Volumn 361, Issue 9353, 2003, Pages 228-230

  Todd, Jeannie F ^a   Stanley, S A ^a   Roufosse, C A ^a   Bishop, A E ^b   Khoo, B ^a   Bloom, S R ^a   Meeran, K ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; SOMATOSTATIN;

ADULT; AGE; ARTICLE; CASE REPORT; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENDER; HORMONE RELEASE; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; NEUROENDOCRINE TUMOR; PRIORITY JOURNAL; PROTEIN SECRETION; SURGICAL TECHNIQUE;

EID: 0037452225     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(03)12256-8     Document Type: Article

References (5)

1. Hamid Q.A., Bishop A.E., Sikri K.L., Varndell I.M., Bloom S.R., Polak J.M. Imunocytochemical characterization of 10 pancreatic tumours associated with the glucagonoma syndrome using antibodies to seperate regions of the pro-glucagon molecule and other neuroendocrine markers. Histopathology. 10:1986;119-133.
2. Kreymann B., Williams G., Ghatei M.A., Bloom S.R. Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet. 2:1987;1300-1304.
3. Ashton M.A. Strumal carcinoid of the ovary associated with hyperinsulinaemic hypoglycaemia and cutaneous melanosis. Histopathology. 27:1995;463-467.
4. Morgello S., Schwartz E., Horwith M., King M.E., Gordon P., Alonso D.R. Ectopic insulin production by a primary ovarian carcinoid. Cancer. 61:1988;800-805.
5. Edwards C.M., Todd J.F., Ghatei M.A., Bloom S.R. Subcutaneous glucagon-like peptide-1 (7-36) amide is insulinotropic and can cause hypoglycaemia in fasted healthy subjects. Clin Sci (Lond). 95:1998;719-724.