Glucose metabolism in 105 children and adolescents after pancreatectomy for congenital hyperinsulinism

Diabetes Care

Volumn 35, Issue 2, 2012, Pages 198-203

  Beltrand, Jacques ^a   Caquard, Marylène ^a   Arnoux, Jean Baptiste ^a   Laborde, Kathleen ^a   Velho, Gilberto ^b   Verkarre, Virginie ^a   Rahier, Jacques ^c   Brunelle, Francis ^a   Nihoul Fékété, Claire ^a   Saudubray, Jean Marie ^a   Robert, Jean Jacques ^a   De Lonlay, Pascale ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b INSERM   (France)

^c CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ADOLESCENT; ARTICLE; CHILD; CONGENITAL HYPERINSULINEMIA; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HUMAN; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPOGLYCEMIA; INCIDENCE; INFANT; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; INTRAVENOUS GLUCOSE TOLERANCE TEST; MAJOR CLINICAL STUDY; MALE; NEWBORN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS RESECTION; PRESCHOOL CHILD; SCHOOL CHILD; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADOLESCENT; BLOOD GLUCOSE; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; INFANT, NEWBORN; INSULIN; KAPLAN-MEIER ESTIMATE; MALE; PANCREATECTOMY; PERSISTENT HYPERINSULINEMIA HYPOGLYCEMIA OF INFANCY; TREATMENT OUTCOME;

EID: 84859089485     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc11-1296     Document Type: Article

References (25)

1. Aynsley-Green A, Hussain K, Hall J, et al. Practical management of hyperinsulinism in infancy. Arch Dis Child Fetal Neonatal Ed 2000;82:F98-F107
2. Menni F, de Lonlay P, Sevin C, et al. Neurologic outcomes of 90 neonates and infants with persistent hyperinsulinemic hypoglycemia. Pediatrics 2001; 107:476-479 (Pubitemid 32183179)
3. Hussain K, Cosgrove KE. Fromcongenital hyperinsulinism todiabetes mellitus: the role of pancreatic beta-cell KATP channels. Pediatr Diabetes 2005;6:103-113 (Pubitemid 40916645)
4. Lovvorn HN 3rd, Nance ML, Ferry RJ Jr, Stolte L, Baker L, O'Neill JA Jr, Schnaufer L, Stanley CA, Adzick NS. Congenital hyperinsulinism and the surgeon: lessons learned over 35 years. J Pediatr Surg 1999; 34:786-792
5. Shilyansky J, Fisher S, Cutz E, Perlman K, Filler RM. Is 95% pancreatectomy the procedure of choice for treatment of persistent hyperinsulinemic hypoglycemia of the neonate? J Pediatr Surg 1997;32: 342-346 (Pubitemid 27082183)
6. Thomas CG Jr, Cuenca RE, Azizkhan RG, Underwood LE, Carney CN. Changing concepts of islet cell dysplasia in neonatal and infantile hyperinsulinism. World J Surg 1988;12:598-609
7. Thomas CG Jr, Underwood LE, Carney CN, Dolcourt JL, Whitt JJ. Neonatal and infantile hypoglycemia due to insulin excess: new aspects of diagnosis and surgical management. Ann Surg 1977;185: 505-517 (Pubitemid 8091205)
8. Sempoux C, Guiot Y, Dahan K, et al. The focal form of persistent hyperinsulinemic hypoglycemia of infancy: morphological and molecular studies show structural and functional differences with insulinoma. Diabetes 2003;52:784-794 (Pubitemid 36323587)
9. Jack MM, Walker RM, Thomsett MJ, Cotterill AM, Bell JR. Histologic findings inpersistent hyperinsulinemic hypoglycemia of infancy: Australian experience. Pediatr Dev Pathol 2000;3:532-547
10. Fékété CN, de Lonlay P, Jaubert F, Rahier J, Brunelle F, Saudubray JM. The surgical management of congenital hyperinsulinemic hypoglycemia in infancy. J Pediatr Surg 2004;39:267-269 (Pubitemid 38338332)
11. Brunelle F, Negre V, Barth MO, et al. Pancreatic venous samplings ininfants and children with primary hyperinsulinism. Pediatr Radiol 1989;19:100-103 (Pubitemid 19048667)
12. Doppman JL, Miller DL, Chang R, Shawker TH, Gorden P, Norton JA. Insulinomas: localization with selective intraarterial injection of calcium. Radiology 1991;178:237-241
13. 18F]fluoro-L-dihydroxyphenylalanine (DOPA) positron emission tomography and immunohistochemistry study of DOPA decarboxylase and insulin secretion. J Clin Endocrinol Metab 2006;91:933-940
14. Cade A,Walters M, Puntis JW, Arthur RJ, Stringer MD. Pancreatic exocrine and endocrine function after pancreatectomy for persistent hyperinsulinaemic hypoglycaemia of infancy. Arch Dis Child 1998;79:435-439 (Pubitemid 28496004)
15. de Lonlay-Debeney P, Poggi-Travert F, Fournet JC, et al. Clinical features of 52 neonates with hyperinsulinism. N Engl J Med 1999;340:1169-1175 (Pubitemid 29177876)
16. Jack MM, Greer RM, Thomsett MJ, et al. The outcome inAustralian children with hyperinsulinism of infancy: early extensive surgery in severe cases lowers risk of diabetes. Clin Endocrinol (Oxf) 2003;58: 355-364 (Pubitemid 36308125)
17. Rother KI, Matsumoto JM, Rasmussen NH, Schwenk WF. Subtotal pancreatectomy for hypoglycemia due to congenital hyperinsulinism: long-term follow-up of neurodevelopmental and pancreatic function. Pediatr Diabetes 2001;2:115-122 (Pubitemid 32734368)
18. Rahier J, Fält K, Müntefering H, Becker K, Gepts W, Falkmer S. The basic structural lesion of persistent neonatal hypoglycaemia with hyperinsulinism: deficiency of pancreatic D cells or hyperactivity of B cells? Diabetologia 1984;26:282-289 (Pubitemid 14137826)
19. Rahier J, Sempoux C, Fournet JC, et al. Partial ornear-total pancreatectomy for persistent neonatal hyperinsulinaemic hypoglycaemia: the pathologist's role. Histopathology 1998;32:15-19
20. Stumvoll M, Mitrakou A, Pimenta W, et al. Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity. Diabetes Care 2000;23:295-301 (Pubitemid 30131733)
21. Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care 2004;27:1487-1495
22. Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22:1462-1470 (Pubitemid 29418240)
23. Giurgea I, Sempoux C, Bellanné-Chantelot C, et al. The Knudson's two-hit model and timing of somatic mutation may account for the phenotypic diversity of focal congenital hyperinsulinism. J Clin Endocrinol Metab 2006;91:4118-4123
24. Leibowitz G, Glaser B, Higazi AA, Salameh M, Cerasi E, Landau H. Hyperinsulinemic hypoglycemia of infancy (nesidioblastosis) in clinical remission: high incidence of diabetes mellitus and persistent beta-cell dysfunction at long-term follow-up. J Clin Endocrinol Metab 1995;80:386-392
25. Mazor-Aronovitch K, Landau H, Gillis D. Surgical versus non-surgical treatment of congenital hyperinsulinism. Pediatr Endocrinol Rev 2009;6:424-430