Deficiency in TNFRSF13B (TACI) expands T-follicular helper and germinal center B cells via increased ICOS-ligand expression but impairs plasma cell survival

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 38, 2012, Pages 15401-15406

  Ou, Xijun ^a   Xu, Shengli ^a,b   Lam, Kong Peng ^a,b,c  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Costimulation; T cell dependent humoral immunity; TNF receptor

Indexed keywords

BIM PROTEIN; INDUCIBLE T CELL COSTIMULATOR LIGAND; THYMUS DEPENDENT ANTIGEN; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL EXPANSION; CELL SURVIVAL; CONTROLLED STUDY; GERMINAL CENTER; HELPER CELL; HUMORAL IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SECRETORY CELL; T FOLLICULAR HELPER CELL; UPREGULATION;

ANIMALS; AUTOIMMUNITY; B-LYMPHOCYTES; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GERMINAL CENTER; HUMANS; IMMUNE SYSTEM; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; LIGANDS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PLASMA CELLS; RECEPTORS, TUMOR NECROSIS FACTOR; T-LYMPHOCYTES, HELPER-INDUCER; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN;

MUS;

EID: 84866564120     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1200386109     Document Type: Article

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