Length of polyglutamine tract affects secondary and tertiary structures of huntingtin protein

International Journal of Biological Macromolecules

Volumn 51, Issue 5, 2012, Pages 920-925

  Vachharajani, Shivang N ^a   Chaudhary, Rajeev Kumar ^a   Prasad, Shivcharan ^a   Roy, Ipsita ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Chaotrope; Huntingtin; Huntington's disease; Polyglutamine; Protein stability

Indexed keywords

GLUTAMINE; GUANIDINE; HUNTINGTIN; MUTANT PROTEIN; POLYGLUTAMINE; UREA;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EQUILIBRIUM CONSTANT; LONG TERM EXPOSURE; PROTEIN AGGREGATION; PROTEIN DENATURATION; PROTEIN REFOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; PROTEIN UNFOLDING; RESIDUE ANALYSIS; STRUCTURE ANALYSIS;

EID: 84866558620     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2012.07.022     Document Type: Article

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