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Volumn 181, Issue 4, 2012, Pages 1316-1326

Prostaglandin reductase 2 modulates ros-mediated cell death and tumor transformation of gastric cancer cells and is associated with higher mortality in gastric cancer patients

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXIDOREDUCTASE; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN REDUCTASE 2; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 84866522945     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.07.006     Document Type: Article
Times cited : (15)

References (59)
  • 1
    • 5044224294 scopus 로고    scopus 로고
    • Molecular biology of gastric cancer: Helicobacter infection and gastric adenocarcinoma: Bacterial and host factors responsible for altered growth signaling
    • DOI 10.1016/j.gene.2004.07.023, PII S0378111904004640
    • C. Stoicov, R. Saffari, X. Cai, C. Hasyagar, J. Houghton Molecular biology of gastric cancer: Helicobacter infection and gastric adenocarcinoma: bacterial and host factors responsible for altered growth signaling Gene 341 2004 1 17 (Pubitemid 39335879)
    • (2004) Gene , vol.341 , Issue.1-2 , pp. 1-17
    • Stoicov, C.1    Saffari, R.2    Cai, X.3    Hasyagar, C.4    Houghton, J.5
  • 2
    • 70649093715 scopus 로고    scopus 로고
    • Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer
    • T. Matsuzaki, M. Yashiro, R. Kaizaki, K. Yasuda, Y. Doi, T. Sawada, M. Ohira, K. Hirakawa Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer Cancer Sci 100 2009 2402 2410
    • (2009) Cancer Sci , vol.100 , pp. 2402-2410
    • Matsuzaki, T.1    Yashiro, M.2    Kaizaki, R.3    Yasuda, K.4    Doi, Y.5    Sawada, T.6    Ohira, M.7    Hirakawa, K.8
  • 3
    • 44449122711 scopus 로고    scopus 로고
    • Anti-proliferative and chemosensitizing effects of luteolin on human gastric cancer AGS cell line
    • B. Wu, Q. Zhang, W. Shen, J. Zhu Anti-proliferative and chemosensitizing effects of luteolin on human gastric cancer AGS cell line Mol Cell Biochem 313 2008 125 132
    • (2008) Mol Cell Biochem , vol.313 , pp. 125-132
    • Wu, B.1    Zhang, Q.2    Shen, W.3    Zhu, J.4
  • 4
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • DOI 10.1136/gut.2004.047100
    • D. Wang, R.N. Dubois Prostaglandins and cancer Gut 55 2006 115 122 (Pubitemid 41820645)
    • (2006) Gut , vol.55 , Issue.1 , pp. 115-122
    • Wang, D.1    Dubois, R.N.2
  • 5
    • 36148978529 scopus 로고    scopus 로고
    • Cyclooxygenases, prostanoids, and tumor progression
    • DOI 10.1007/s10555-007-9096-5, Forty Years of Metastasis Research: A Tribute to Dr. Isaiah J. Fidler
    • M.T. Wang, K.V. Honn, D. Nie Cyclooxygenases, prostanoids, and tumor progression Cancer Metastasis Rev 26 2007 525 534 (Pubitemid 350115125)
    • (2007) Cancer and Metastasis Reviews , vol.26 , Issue.3-4 , pp. 525-534
    • Wang, M.-T.1    Honn, K.V.2    Nie, D.3
  • 6
    • 33845716751 scopus 로고    scopus 로고
    • 15-Deoxy-Δ12,14-prostaglandin J2 enhances docetaxel anti-tumor activity against A549 and H460 non-small-cell lung cancer cell lines and xenograft tumors
    • DOI 10.1097/CAD.0b013e3280101006, PII 0000181320070100000009
    • S.V. Fulzele, A. Chatterjee, M.S. Shaik, T. Jackson, N. Ichite, M. Singh 15-Deoxy-Delta12,14-prostaglandin J2 enhances docetaxel anti-tumor activity against A549 and H460 non-small-cell lung cancer cell lines and xenograft tumors Anticancer Drugs 18 2007 65 78 (Pubitemid 44963416)
    • (2007) Anti-Cancer Drugs , vol.18 , Issue.1 , pp. 65-78
    • Fulzele, S.V.1    Chatterjee, A.2    Shaik, M.S.3    Jackson, T.4    Ichite, N.5    Singh, M.6
  • 7
    • 0032586875 scopus 로고    scopus 로고
    • Activation of PPARγ inhibits cell growth and induces apoptosis in human gastric cancer cells
    • DOI 10.1016/S0014-5793(99)00871-6, PII S0014579399008716
    • N. Takahashi, T. Okumura, W. Motomura, Y. Fujimoto, I. Kawabata, Y. Kohgo Activation of PPARgamma inhibits cell growth and induces apoptosis in human gastric cancer cells FEBS Lett 455 1999 135 139 (Pubitemid 29322796)
    • (1999) FEBS Letters , vol.455 , Issue.1-2 , pp. 135-139
    • Takahashi, N.1    Okumura, T.2    Motomura, W.3    Fujimoto, Y.4    Kawabata, I.5    Kohgo, Y.6
  • 8
    • 10744231241 scopus 로고    scopus 로고
    • Effect of peroxisome proliferator activated receptor γ ligands on growth and gene expression profiles of gastric cancer cells
    • DOI 10.1136/gut.2003.021105
    • W.K. Leung, A.H. Bai, V.Y. Chan, J. Yu, M.W. Chan, K.F. To, J.R. Wu, K.K. Chan, Y.G. Fu, F.K. Chan, J.J. Sung Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells Gut 53 2004 331 338 (Pubitemid 38241325)
    • (2004) Gut , vol.53 , Issue.3 , pp. 331-338
    • Leung, W.K.1    Bai, A.2    Chan, V.Y.W.3    Yu, J.4    Chan, M.W.Y.5    To, K.-F.6    Wu, J.-R.7    Chan, K.-K.8    Fu, Y.-G.9    Chan, F.K.L.10    Sung, J.J.Y.11
  • 9
    • 7944236430 scopus 로고    scopus 로고
    • Implication of peroxisome proliferator-activated receptor γ and proinflammatory cytokines in gastric carcinogenesis: Link to Helicobacter pylori-infection
    • DOI 10.1254/jphs.FPJ04016X
    • P.C. Konturek, J. Kania, V. Kukharsky, M. Raithel, M. Ocker, K. Rembiasz, E.G. Hahn, S.J. Konturek Implication of peroxisome proliferator-activated receptor gamma and proinflammatory cytokines in gastric carcinogenesis: link to Helicobacter pylori-infection J Pharmacol Sci 96 2004 134 143 (Pubitemid 39469604)
    • (2004) Journal of Pharmacological Sciences , vol.96 , Issue.2 , pp. 134-143
    • Konturek, P.C.1    Kania, J.2    Kukharsky, V.3    Raithel, M.4    Ocker, M.5    Rembiasz, K.6    Hahn, E.G.7    Konturek, S.J.8
  • 10
    • 0142152189 scopus 로고    scopus 로고
    • 2 inhibits cell growth and induces apoptosis of MCG-803 human gastric cancer cell line
    • Y.X. Chen, X.Y. Zhong, Y.F. Qin, W. Bing, L.Z. He 15d-PGJ2 inhibits cell growth and induces apoptosis of MCG-803 human gastric cancer cell line World J Gastroenterol 9 2003 2149 2153 (Pubitemid 37321434)
    • (2003) World Journal of Gastroenterology , vol.9 , Issue.10 , pp. 2149-2153
    • Chen, Y.-X.1    Zhong, X.-Y.2    Qin, Y.-F.3    Bing, W.4    He, L.-Z.5
  • 11
    • 70350518970 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma
    • X.M. Ma, H. Yu, N. Huai Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma World J Gastroenterol 15 2009 3874 3883
    • (2009) World J Gastroenterol , vol.15 , pp. 3874-3883
    • Ma, X.M.1    Yu, H.2    Huai, N.3
  • 13
    • 34547101243 scopus 로고    scopus 로고
    • 2 catabolism in regulation of peroxisome proliferator-activated receptor γ activation
    • DOI 10.1074/jbc.M702289200
    • W.L. Chou, L.M. Chuang, C.C. Chou, A.H. Wang, J.A. Lawson, G.A. FitzGerald, Z.F. Chang Identification of a novel prostaglandin reductase reveals the involvement of prostaglandin E2 catabolism in regulation of peroxisome proliferator-activated receptor gamma activation J Biol Chem 282 2007 18162 18172 (Pubitemid 47100215)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.25 , pp. 18162-18172
    • Chou, W.-L.1    Chuang, L.-M.2    Chou, C.-C.3    Wang, A.H.-J.4    Lawson, J.A.5    FitzGerald, G.A.6    Chang, Z.-F.7
  • 14
    • 55249106494 scopus 로고    scopus 로고
    • Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2
    • Y.H. Wu, T.P. Ko, R.T. Guo, S.M. Hu, L.M. Chuang, A.H. Wang Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2 Structure 16 2008 1714 1723
    • (2008) Structure , vol.16 , pp. 1714-1723
    • Wu, Y.H.1    Ko, T.P.2    Guo, R.T.3    Hu, S.M.4    Chuang, L.M.5    Wang, A.H.6
  • 16
    • 34948881208 scopus 로고    scopus 로고
    • Mitochondria: A hub of redox activities and cellular distress control
    • DOI 10.1007/s11010-007-9520-8
    • P. Kakkar, B.K. Singh Mitochondria: a hub of redox activities and cellular distress control Mol Cell Biochem 305 2007 235 253 (Pubitemid 47517185)
    • (2007) Molecular and Cellular Biochemistry , vol.305 , Issue.1-2 , pp. 235-253
    • Kakkar, P.1    Singh, B.K.2
  • 17
    • 33749178260 scopus 로고    scopus 로고
    • Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
    • DOI 10.1016/j.bbabio.2006.06.014, PII S000527280600212X, Mitochondria: from Molecular Insight to Physiology and Pathology
    • N. Festjens, T. Vanden Berghe, P. Vandenabeele Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response Biochim Biophys Acta 1757 2006 1371 1387 (Pubitemid 44472550)
    • (2006) Biochimica et Biophysica Acta - Bioenergetics , vol.1757 , Issue.9-10 , pp. 1371-1387
    • Festjens, N.1    Vanden Berghe, T.2    Vandenabeele, P.3
  • 18
    • 77953488144 scopus 로고    scopus 로고
    • Mitochondria as decision-makers in cell death
    • V. Borutaite Mitochondria as decision-makers in cell death Environ Mol Mutagen 51 2010 406 416
    • (2010) Environ Mol Mutagen , vol.51 , pp. 406-416
    • Borutaite, V.1
  • 19
    • 44449147036 scopus 로고    scopus 로고
    • Tumor Cell Metabolism: Cancer's Achilles' Heel
    • DOI 10.1016/j.ccr.2008.05.005, PII S1535610808001608
    • G. Kroemer, J. Pouyssegur Tumor cell metabolism: cancer's Achilles' heel Cancer Cell 13 2008 472 482 (Pubitemid 351766797)
    • (2008) Cancer Cell , vol.13 , Issue.6 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 20
    • 79954459921 scopus 로고    scopus 로고
    • Regulation of mitochondrial metabolism: Yet another facet in the biology of the oncoprotein Bcl-2
    • S. Krishna, I.C. Low, S. Pervaiz Regulation of mitochondrial metabolism: yet another facet in the biology of the oncoprotein Bcl-2 Biochem J 435 2011 545 551
    • (2011) Biochem J , vol.435 , pp. 545-551
    • Krishna, S.1    Low, I.C.2    Pervaiz, S.3
  • 21
    • 0036644215 scopus 로고    scopus 로고
    • Regulation and measurement of oxidative stress in apoptosis
    • DOI 10.1016/S0022-1759(02)00070-4, PII S0022175902000704
    • J.F. Curtin, M. Donovan, T.G. Cotter Regulation and measurement of oxidative stress in apoptosis J Immunol Methods 265 2002 49 72 (Pubitemid 34628804)
    • (2002) Journal of Immunological Methods , vol.265 , Issue.1-2 , pp. 49-72
    • Curtin, J.F.1    Donovan, M.2    Cotter, T.G.3
  • 22
    • 64149087422 scopus 로고    scopus 로고
    • Therapeutic strategies by modulating oxygen stress in cancer and inflammation
    • J. Fang, T. Seki, H. Maeda Therapeutic strategies by modulating oxygen stress in cancer and inflammation Adv Drug Deliv Rev 61 2009 290 302
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 290-302
    • Fang, J.1    Seki, T.2    Maeda, H.3
  • 23
    • 73649089980 scopus 로고    scopus 로고
    • ERK and cell death: Mechanisms of ERK-induced cell death-apoptosis, autophagy and senescence
    • S. Cagnol, J.C. Chambard ERK and cell death: mechanisms of ERK-induced cell death-apoptosis, autophagy and senescence FEBS J 277 2010 2 21
    • (2010) FEBS J , vol.277 , pp. 2-21
    • Cagnol, S.1    Chambard, J.C.2
  • 24
    • 34548451974 scopus 로고    scopus 로고
    • Reactive oxygen species in mitochondria-mediated cell death
    • DOI 10.1080/03602530701468516, PII 781828662
    • S. Orrenius Reactive oxygen species in mitochondria-mediated cell death Drug Metab Rev 39 2007 443 455 (Pubitemid 47355728)
    • (2007) Drug Metabolism Reviews , vol.39 , Issue.2-3 , pp. 443-455
    • Orrenius, S.1
  • 28
    • 76249133498 scopus 로고    scopus 로고
    • Distinct antiviral roles for human 2′,5′-oligoadenylate synthetase family members against dengue virus infection
    • R.J. Lin, H.P. Yu, B.L. Chang, W.C. Tang, C.L. Liao, Y.L. Lin Distinct antiviral roles for human 2′,5′-oligoadenylate synthetase family members against dengue virus infection J Immunol 183 2009 8035 8043
    • (2009) J Immunol , vol.183 , pp. 8035-8043
    • Lin, R.J.1    Yu, H.P.2    Chang, B.L.3    Tang, W.C.4    Liao, C.L.5    Lin, Y.L.6
  • 29
    • 77951207164 scopus 로고    scopus 로고
    • TCF7L2 genetic variants and progression to diabetes in the Chinese population: Pleiotropic effects on insulin secretion and insulin resistance
    • Y.C. Chang, Y.F. Chiu, L.L. Ho, C.T. Ting, K.C. Shih, J.D. Curb, Y.D. Chen, H.Y. Li, L.M. Chuang TCF7L2 genetic variants and progression to diabetes in the Chinese population: pleiotropic effects on insulin secretion and insulin resistance J Mol Med (Berl) 88 2010 183 192
    • (2010) J Mol Med (Berl) , vol.88 , pp. 183-192
    • Chang, Y.C.1    Chiu, Y.F.2    Ho, L.L.3    Ting, C.T.4    Shih, K.C.5    Curb, J.D.6    Chen, Y.D.7    Li, H.Y.8    Chuang, L.M.9
  • 30
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • K.J. Livak, T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method Methods 25 2001 402 408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 32
    • 0032939619 scopus 로고    scopus 로고
    • Rho GTPases are over-expressed in human tumors
    • DOI 10.1002/(SICI)1097-0215(19990531)81:5<682::AID-IJC2>3.0.CO;2-B
    • G. Fritz, I. Just, B. Kaina Rho GTPases are over-expressed in human tumors Int J Cancer 81 1999 682 687 (Pubitemid 29214373)
    • (1999) International Journal of Cancer , vol.81 , Issue.5 , pp. 682-687
    • Fritz, G.1    Just, I.2    Kaina, B.3
  • 33
    • 79952703288 scopus 로고    scopus 로고
    • Cell metabolism: An essential link between cell growth and apoptosis
    • E.F. Mason, J.C. Rathmell Cell metabolism: an essential link between cell growth and apoptosis Biochim Biophys Acta 1813 2011 645 654
    • (2011) Biochim Biophys Acta , vol.1813 , pp. 645-654
    • Mason, E.F.1    Rathmell, J.C.2
  • 34
    • 77954542997 scopus 로고    scopus 로고
    • Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells
    • C. Favre, A. Zhdanov, M. Leahy, D. Papkovsky, R. O'Connor Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells Oncogene 29 2010 3964 3976
    • (2010) Oncogene , vol.29 , pp. 3964-3976
    • Favre, C.1    Zhdanov, A.2    Leahy, M.3    Papkovsky, D.4    O'Connor, R.5
  • 35
    • 33646165559 scopus 로고    scopus 로고
    • Efficient execution of cell death in non-glycolytic cells requires the generation of ROS controlled by the activity of mitochondrial H+-ATP synthase
    • G. Santamaria, M. Martínez-Diez, I. Fabregat, J.M. Cuezva Efficient execution of cell death in non-glycolytic cells requires the generation of ROS controlled by the activity of mitochondrial H+-ATP synthase Carcinogenesis 27 2006 925 935
    • (2006) Carcinogenesis , vol.27 , pp. 925-935
    • Santamaria, G.1    Martínez-Diez, M.2    Fabregat, I.3    Cuezva, J.M.4
  • 36
    • 65949119310 scopus 로고    scopus 로고
    • How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer
    • Y. Mebratu, Y. Tesfaigzi How ERK1/2 activation controls cell proliferation and cell death: is subcellular localization the answer Cell Cycle 8 2009 1168 1175
    • (2009) Cell Cycle , vol.8 , pp. 1168-1175
    • Mebratu, Y.1    Tesfaigzi, Y.2
  • 38
    • 0037271412 scopus 로고    scopus 로고
    • Inducing cancer cell death by targeting transcription factors
    • DOI 10.1097/00001813-200301000-00002
    • R. Kim, K. Tanabe, M. Emi, Y. Uchida, H. Inoue, T. Toge Inducing cancer cell death by targeting transcription factors Anticancer Drugs 14 2003 3 11 (Pubitemid 36177349)
    • (2003) Anti-Cancer Drugs , vol.14 , Issue.1 , pp. 3-11
    • Kim, R.1    Tanabe, K.2    Emi, M.3    Uchida, Y.4    Inoue, H.5    Toge, T.6
  • 39
    • 26444495516 scopus 로고    scopus 로고
    • Diversity of gastric carcinogenesis
    • M. Kaminishi Diversity of gastric carcinogenesis Oncology 69 Suppl 1 2005 1 8
    • (2005) Oncology , vol.69 , Issue.SUPPL. 1 , pp. 1-8
    • Kaminishi, M.1
  • 40
    • 84855591618 scopus 로고    scopus 로고
    • Inhibition of peroxisome proliferator-activated receptor-gamma in myeloid lineage cells induces systemic inflammation, immunosuppression and tumorigenesis
    • L. Wu, C. Yan, M. Czader, O. Foreman, J.S. Blum, R. Kapur, H. Du Inhibition of peroxisome proliferator-activated receptor-gamma in myeloid lineage cells induces systemic inflammation, immunosuppression and tumorigenesis Blood 119 2012 115 126
    • (2012) Blood , vol.119 , pp. 115-126
    • Wu, L.1    Yan, C.2    Czader, M.3    Foreman, O.4    Blum, J.S.5    Kapur, R.6    Du, H.7
  • 41
    • 84055217307 scopus 로고    scopus 로고
    • Crosstalk between the canonical NF-kappaB and Notch signaling pathways inhibits Ppargamma expression and promotes pancreatic cancer progression in mice
    • E. Maniati, M. Bossard, N. Cook, J.B. Candido, N. Emami-Shahri, S.A. Nedospasov, F.R. Balkwill, D.A. Tuveson, T. Hagemann Crosstalk between the canonical NF-kappaB and Notch signaling pathways inhibits Ppargamma expression and promotes pancreatic cancer progression in mice J Clin Invest 121 2011 4685 4699
    • (2011) J Clin Invest , vol.121 , pp. 4685-4699
    • Maniati, E.1    Bossard, M.2    Cook, N.3    Candido, J.B.4    Emami-Shahri, N.5    Nedospasov, S.A.6    Balkwill, F.R.7    Tuveson, D.A.8    Hagemann, T.9
  • 42
    • 2042443068 scopus 로고    scopus 로고
    • Tumor growth inhibition by indomethacin in a mouse model of human medullary thyroid cancer: Implication of cyclooxygenases and 15-hydroxyprostaglandin dehydrogenase
    • DOI 10.1210/en.2003-0915
    • V. Quidville, N. Segond, E. Pidoux, R. Cohen, A. Jullienne, S. Lausson Tumor growth inhibition by indomethacin in a mouse model of human medullary thyroid cancer: implication of cyclooxygenases and 15-hydroxyprostaglandin dehydrogenase Endocrinology 145 2004 2561 2571 (Pubitemid 38535084)
    • (2004) Endocrinology , vol.145 , Issue.5 , pp. 2561-2571
    • Quidville, V.1    Segond, N.2    Pidoux, E.3    Cohen, R.4    Jullienne, A.5    Lausson, S.6
  • 43
    • 0041409648 scopus 로고    scopus 로고
    • Activity of the non-steroidal anti-inflammatory drug indomethacin against colorectal cancer
    • DOI 10.1016/S0305-7372(03)00014-8
    • M.A. Hull, S.H. Gardner, G. Hawcroft Activity of the non-steroidal anti-inflammatory drug indomethacin against colorectal cancer Cancer Treat Rev 29 2003 309 320 (Pubitemid 37069661)
    • (2003) Cancer Treatment Reviews , vol.29 , Issue.4 , pp. 309-320
    • Hull, M.A.1    Gardner, S.H.2    Hawcroft, G.3
  • 44
    • 0031903711 scopus 로고    scopus 로고
    • Bcl-2 expression as a prognostic factor of survival of gastric carcinoma
    • T. Inada, S. Kikuyama, A. Ichikawa, S. Igarashi, Y. Ogata Bcl-2 expression as a prognostic factor of survival of gastric carcinoma Anticancer Res 18 1998 2003 2010 (Pubitemid 28344862)
    • (1998) Anticancer Research , vol.18 , Issue.3 , pp. 2003-2010
    • Inada, T.1    Kikuyama, S.2    Ichikawa, A.3    Igarashi, S.4    Ogata, Y.5
  • 45
    • 0031018119 scopus 로고    scopus 로고
    • Apoptosis, cell proliferation and expression of Bcl-2 and Bax in gastric carcinomas: Immunohistochemical and clinicopathological study
    • Y. Koshida, M. Saegusa, I. Okayasu Apoptosis, cell proliferation and expression of Bcl-2 and Bax in gastric carcinomas: immunohistochemical and clinicopathological study Br J Cancer 75 1997 367 373 (Pubitemid 27051051)
    • (1997) British Journal of Cancer , vol.75 , Issue.3 , pp. 367-373
    • Koshida, Y.1    Saegusa, M.2    Okayasu, I.3
  • 46
    • 0029066597 scopus 로고
    • Bcl-2 expression and its association with cell kinetics in human gastric carcinomas and intestinal metaplasia
    • M. Saegusa, Y. Takano, I. Okayasu Bcl-2 expression and its association with cell kinetics in human gastric carcinomas and intestinal metaplasia J Cancer Res Clin Oncol 121 1995 357 363
    • (1995) J Cancer Res Clin Oncol , vol.121 , pp. 357-363
    • Saegusa, M.1    Takano, Y.2    Okayasu, I.3
  • 47
    • 23344436292 scopus 로고    scopus 로고
    • Molecular markers in gastric cancer: Can p53 and bcl-2 protein expressions be used as prognostic factors?
    • K. Zafirellis, A. Karameris, N. Milingos, G. Androulakis Molecular markers in gastric cancer: can p53 and bcl-2 protein expressions be used as prognostic factors Anticancer Res 25 2005 3629 3636 (Pubitemid 41105253)
    • (2005) Anticancer Research , vol.25 , Issue.5 , pp. 3629-3636
    • Zafirellis, K.1    Karameris, A.2    Milingos, N.3    Androulakis, G.4
  • 49
    • 0029787341 scopus 로고    scopus 로고
    • Different expression of Bcl-2 in diffuse and intestinal type stomach carcinomas
    • R. Klein, H. Vollmers, H. Mullerhermelink Different expression of Bcl-2 in diffuse and intestinal type stomach carcinomas Oncology Rep 3 1996 825 828 (Pubitemid 26323731)
    • (1996) Oncology Reports , vol.3 , Issue.5 , pp. 825-828
    • Klein, R.1    Vollmers, H.P.2    Muller-Hermelink, H.K.3
  • 51
    • 0027476151 scopus 로고
    • Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA
    • DOI 10.1038/361365a0
    • M.D. Jacobson, J.F. Burne, M.P. King, T. Miyashita, J.C. Reed, M.C. Raff Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA Nature 361 1993 365 369 (Pubitemid 23041631)
    • (1993) Nature , vol.361 , Issue.6410 , pp. 365-369
    • Jacobson, M.D.1    Burne, J.F.2    King, M.P.3    Miyashita, T.4    Reed, J.C.5    Raff, M.C.6
  • 52
    • 0034629336 scopus 로고    scopus 로고
    • Lack of oxidative phosphorylation and low mitochondrial membrane potential decrease susceptibility to apoptosis and do not modulate the protective effect of Bcl-x(L) in osteosarcoma cells
    • DOI 10.1074/jbc.275.10.7087
    • R. Dey, C.T. Moraes Lack of oxidative phosphorylation and low mitochondrial membrane potential decrease susceptibility to apoptosis and do not modulate the protective effect of Bcl-x(L) in osteosarcoma cells J Biol Chem 275 2000 7087 7094 (Pubitemid 30146256)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.10 , pp. 7087-7094
    • Dey, R.1    Moraes, C.T.2
  • 53
    • 34548036251 scopus 로고    scopus 로고
    • Bcl-2 induces pro-oxidant state by engaging mitochondrial respiration in tumor cells
    • DOI 10.1038/sj.cdd.4402165, PII 4402165
    • Z.X. Chen, S. Pervaiz Bcl-2 induces pro-oxidant state by engaging mitochondrial respiration in tumor cells [Erratum appeared in Cell Death Differ 2012, 19:551] Cell Death Differ 14 2007 1617 1627 (Pubitemid 47278847)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.9 , pp. 1617-1627
    • Chen, Z.X.1    Pervaiz, S.2
  • 54
    • 76749120374 scopus 로고    scopus 로고
    • Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2
    • Z.X. Chen, S. Pervaiz Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2 Cell Death Differ 17 2010 408 420
    • (2010) Cell Death Differ , vol.17 , pp. 408-420
    • Chen, Z.X.1    Pervaiz, S.2
  • 56
    • 34247099457 scopus 로고    scopus 로고
    • Differential expression of manganese superoxide dismutase, copper/zinc superoxide dismutase, and catalase in gastric adenocarcinoma and normal gastric mucosa
    • DOI 10.1016/j.ejso.2006.10.024, PII S0748798306004100
    • T.S. Hwang, H.K. Choi, H.S. Han Differential expression of manganese superoxide dismutase, copper/zinc superoxide dismutase, and catalase in gastric adenocarcinoma and normal gastric mucosa Eur J Surg Oncol 33 2007 474 479 (Pubitemid 46591167)
    • (2007) European Journal of Surgical Oncology , vol.33 , Issue.4 , pp. 474-479
    • Hwang, T.S.1    Choi, H.K.2    Han, H.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.