Dioscoreanone suppresses LPS-induced nitric oxide production and inflammatory cytokine expression in RAW 264.7 macrophages by NF-κB and ERK1/2 signaling transduction

Journal of Cellular Biochemistry

Volumn 113, Issue 11, 2012, Pages 3427-3435

  Itharat, Arunporn ^a   Hiransai, Poonsit ^b,c  

^a THAMMASAT UNIVERSITY   (Thailand)

^b WALAILAK UNIVERSITY   (Thailand)

^c PRINCE OF SONGKLA UNIVERSITY   (Thailand)

Author keywords

Dioscorea membranacea; INFLAMMATORY CYTOKINES; NITRIC OXIDE PRODUCTION; PHENANTHRAQUINONE; RAW 264.7 CELLS

Indexed keywords

ACETYLCYSTEINE; ANTIINFLAMMATORY AGENT; DICOUMAROL; DIOSCOREANONE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL LINE; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; DRUG MECHANISM; IC 50; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ACETYLCYSTEINE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GENES, REPORTER; INHIBITORY CONCENTRATION 50; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LUCIFERASES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHENANTHRENES; QUINONES;

DIOSCOREA MEMBRANACEA;

EID: 84866517631     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24219     Document Type: Article

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