Dioscorealides and dioscoreanone, novel cytotoxic naphthofuranoxepins, and 1,4-phenanthraquinone from Dioscorea membranacea Pierre

Organic Letters

Volumn 5, Issue 16, 2003, Pages 2879-2882

  Itharat, Arunporn ^a   Plubrukarn, Anuchit ^b   Kongsaeree, Palangpon ^c   Bui, Tam ^a   Keawpradub, Niwat ^b   Houghton, Peter J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b PRINCE OF SONGKLA UNIVERSITY   (Thailand)

^c MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 PHENANTHRAQUINONE; ANTINEOPLASTIC AGENT; DIOSCOREA MEMBRANACEA PIERRE EXTRACT; DIOSCOREALIDE A; DIOSCOREALIDE B; DIOSCOREANONE; NAPHTHOFURANOXEPIN A; NAPHTHOFURANOXEPIN B; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CIRCULAR DICHROISM; CYTOTOXICITY; DIOSCOREA MEMBRANACEA PIERRE; DRUG SYNTHESIS; MEDICINAL PLANT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RHIZOME; X RAY CRYSTALLOGRAPHY; YAM;

EID: 0141631703     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol034926y     Document Type: Article

References (5)

1. Boonyaratanakornkit, L.; Chantarateptavan, V. Thai J. Pharm. Sci. 1993, 1, 79-90.
2. Dioscorea membranacea Pierre was kindly identified by Dr. Tippan Sdakorn of the Department of Forestry, Ministry of Agriculture and Cooperation, and by Mr. Cherdsak Thapyai of the Faculty of Pharmaceutical Sciences, Naresuan University. The authentic specimen is deposited at the herbarium of the Department of Forestry, Bangkok, Thailand.
3. +, 100), 267 (9), 254 (22), 231 (19).
4. (a) Skehan, P.; Storeng, R.; Scudiero, D.; Monks, A.; McMahon, J.; Vistica, D.; Warren, J. T.; Bokesch, H.; Kenney, S.; Boyd, M. R. J. Natl. Cancer Inst. 1990, 82, 1107-1112.
5. (b) Sampson, J. H.; Raman, A.; Kerlsen, G.; Navasaria, H.; Leigh, I. M. Phytomedicine 2001, 8, 230-235.