메뉴 건너뛰기




Volumn 41, Issue 4, 2012, Pages 1504-1512

The enhanced antitumor effects of biodegradable cationic heparin-polyethyleneimine nanogels delivering HSulf-1 gene combined with cisplatin on ovarian cancer

Author keywords

Angiogenesis; Apoptosis; Combination therapy; Heparin polyethyleneimine; HSulf 1; Ovarian cancer

Indexed keywords

CD31 ANTIGEN; CISPLATIN; HEPARAN SULFATE; HEPARAN SULFATE 6 ENDOSULFATASE 1; HEPARIN POLYETHYLENEIMINE NANOGEL; KI 67 ANTIGEN; POLYETHYLENEIMINE; UNCLASSIFIED DRUG;

EID: 84866515124     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1558     Document Type: Article
Times cited : (24)

References (40)
  • 1
    • 0036143022 scopus 로고    scopus 로고
    • Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization
    • Shridhar V, Sen A, Chien J, Staub J, Avula R, Kovats S, Lee J, Lillie J and Smith DI: Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization. Cancer Res 62: 262-270, 2002.
    • (2002) Cancer Res , vol.62 , pp. 262-270
    • Shridhar, V.1    Sen, A.2    Chien, J.3    Staub, J.4    Avula, R.5    Kovats, S.6    Lee, J.7    Lillie, J.8    Smith, D.I.9
  • 2
    • 0037147259 scopus 로고    scopus 로고
    • Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans
    • Morimoto-Tomita M, Uchimura K, Werb Z, Hemmerich S and Rosen SD: Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans. J Biol Chem 277: 49175-49185, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 49175-49185
    • Morimoto-Tomita, M.1    Uchimura, K.2    Werb, Z.3    Hemmerich, S.4    Rosen, S.D.5
  • 3
    • 33646188185 scopus 로고    scopus 로고
    • Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2
    • Ai X, Do AT, Kusche-Gullberg M, Lindahl U, Lu K and Emerson CP Jr: Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2. J Biol Chem 281: 4969-4976, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 4969-4976
    • Ai, X.1    Do, A.T.2    Kusche-Gullberg, M.3    Lindahl, U.4    Lu, K.5    Emerson Jr., C.P.6
  • 5
    • 0034797022 scopus 로고    scopus 로고
    • Role of heparan sulfate proteoglycans in cell signaling and cancer
    • Selva EM and Perrimon N: Role of heparan sulfate proteoglycans in cell signaling and cancer. Adv Cancer Res 83: 67-80, 2001.
    • (2001) Adv Cancer Res , vol.83 , pp. 67-80
    • Selva, E.M.1    Perrimon, N.2
  • 6
    • 12344310615 scopus 로고    scopus 로고
    • Functions of heparan sulfate proteoglycans in cell signaling during development
    • Lin X: Functions of heparan sulfate proteoglycans in cell signaling during development. Development 131: 6009-6021, 2004.
    • (2004) Development , vol.131 , pp. 6009-6021
    • Lin, X.1
  • 12
    • 66349097740 scopus 로고    scopus 로고
    • Regulation of HSulf-1 expression by variant hepatic nuclear factor 1 in ovarian cancer
    • Liu P, Khurana A, Rattan R, Kalloger S, Dowdy S, Gilks B and Shridhar V: Regulation of HSulf-1 expression by variant hepatic nuclear factor 1 in ovarian cancer. Cancer Res 69: 4843-4850, 2009.
    • (2009) Cancer Res , vol.69 , pp. 4843-4850
    • Liu, P.1    Khurana, A.2    Rattan, R.3    Kalloger, S.4    Dowdy, S.5    Gilks, B.6    Shridhar, V.7
  • 14
    • 69849092570 scopus 로고    scopus 로고
    • The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis
    • Lai JP, Sandhu DS, Shire AM and Roberts LR: The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis. J Gastrointest Cancer 39: 149-158, 2008.
    • (2008) J Gastrointest Cancer , vol.39 , pp. 149-158
    • Lai, J.P.1    Sandhu, D.S.2    Shire, A.M.3    Roberts, L.R.4
  • 16
    • 2442417750 scopus 로고    scopus 로고
    • Progress in ovarian cancer: An overview and perspective
    • Ozols RF: Progress in ovarian cancer: an overview and perspective. EJC (Suppl) 1: 43-55, 2003.
    • (2003) EJC , vol.1 , Issue.SUPPL. , pp. 43-55
    • Ozols, R.F.1
  • 17
    • 0035060354 scopus 로고    scopus 로고
    • Is cisplatin-induced cell death always produced by apoptosis?
    • Gonzalez VM, Fuertes MA, Alonso C and Perez JM: Is cisplatin-induced cell death always produced by apoptosis? Mol Pharmacol 59: 657-663, 2001.
    • (2001) Mol Pharmacol , vol.59 , pp. 657-663
    • Gonzalez, V.M.1    Fuertes, M.A.2    Alonso, C.3    Perez, J.M.4
  • 18
    • 0037366133 scopus 로고    scopus 로고
    • Biochemical modulation of cisplatin mechanisms of action: Enhancement of antitumor activity and circumvention of drug resistance
    • Fuertes MA, Alonso C and Perez JM: Biochemical modulation of cisplatin mechanisms of action: enhancement of antitumor activity and circumvention of drug resistance. Chem Rev 103: 645-662, 2003.
    • (2003) Chem Rev , vol.103 , pp. 645-662
    • Fuertes, M.A.1    Alonso, C.2    Perez, J.M.3
  • 19
    • 0031791029 scopus 로고    scopus 로고
    • Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy
    • Reed E: Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy. Cancer Treat Rev 24: 331-344, 1998.
    • (1998) Cancer Treat Rev , vol.24 , pp. 331-344
    • Reed, E.1
  • 21
    • 4444370799 scopus 로고    scopus 로고
    • Gene therapy clinical trials worldwide 1989-2004-an overview
    • Edelstein ML, Abedi MR, Wixon J, Edelstein RM: Gene therapy clinical trials worldwide 1989-2004-an overview. J Gene Med 6: 597-602, 2004.
    • (2004) J Gene Med , vol.6 , pp. 597-602
    • Edelstein, M.L.1    Abedi, M.R.2    Wixon, J.3    Edelstein, R.M.4
  • 23
    • 0035941087 scopus 로고    scopus 로고
    • Gene therapy. Safer and virus-free?
    • Ferber D: Gene therapy. Safer and virus-free? Science 294: 1638-1642, 2001.
    • (2001) Science , vol.294 , pp. 1638-1642
    • Ferber, D.1
  • 24
    • 33746438424 scopus 로고    scopus 로고
    • Toxicity of cationic lipids and cationic polymers in gene delivery
    • Lv H, Zhang S, Wang B, Cui S and Yan J: Toxicity of cationic lipids and cationic polymers in gene delivery. J Control Release 114: 100-109, 2006.
    • (2006) J Control Release , vol.114 , pp. 100-109
    • Lv, H.1    Zhang, S.2    Wang, B.3    Cui, S.4    Yan, J.5
  • 25
    • 23944464631 scopus 로고    scopus 로고
    • Recent advances in rational gene transfer vector design based on poly(ethyleneimine) and its derivatives
    • Neu M, Fischer D and Kissel T: Recent advances in rational gene transfer vector design based on poly(ethyleneimine) and its derivatives. J Gene Med 7: 992-1009, 2005.
    • (2005) J Gene Med , vol.7 , pp. 992-1009
    • Neu, M.1    Fischer, D.2    Kissel, T.3
  • 26
    • 0037437033 scopus 로고    scopus 로고
    • Low-molecular-weight polyethyleneimine as a non-viral vector for DNA delivery: Comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethyleneimine
    • Kunath K, von Harpe A, Fischer D, Petersen H, Bickel U, Voigt K and Kissel T: Low-molecular-weight polyethyleneimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethyleneimine. J Control Release 89: 113-125, 2003.
    • (2003) J Control Release , vol.89 , pp. 113-125
    • Kunath, K.1    Von Harpe, A.2    Fischer, D.3    Petersen, H.4    Bickel, U.5    Voigt, K.6    Kissel, T.7
  • 27
    • 62549098542 scopus 로고    scopus 로고
    • A biodegradable low molecular weight polyethyleneimine derivative as low toxicity and efficient gene vector
    • Wen Y, Pan S, Luo X, Zhang X, Zhang W and Feng M: A biodegradable low molecular weight polyethyleneimine derivative as low toxicity and efficient gene vector. Bioconjug Chem 20: 322-332, 2009.
    • (2009) Bioconjug Chem , vol.20 , pp. 322-332
    • Wen, Y.1    Pan, S.2    Luo, X.3    Zhang, X.4    Zhang, W.5    Feng, M.6
  • 28
    • 0035214028 scopus 로고    scopus 로고
    • Efficient gene transfer using reversibly cross-linked low molecular weight polyethyleneimine
    • Gosselin MA, Guo W and Lee RJ: Efficient gene transfer using reversibly cross-linked low molecular weight polyethyleneimine. Bioconjug Chem 12: 989-994, 2001.
    • (2001) Bioconjug Chem , vol.12 , pp. 989-994
    • Gosselin, M.A.1    Guo, W.2    Lee, R.J.3
  • 29
    • 0141569730 scopus 로고    scopus 로고
    • A degradable polyethyleneimine derivative with low toxicity for highly efficient gene delivery
    • Forrest ML, Koerber JT and Pack DW: A degradable polyethyleneimine derivative with low toxicity for highly efficient gene delivery. Bioconjug Chem 14: 934-940, 2003.
    • (2003) Bioconjug Chem , vol.14 , pp. 934-940
    • Forrest, M.L.1    Koerber, J.T.2    Pack, D.W.3
  • 30
    • 56949101336 scopus 로고    scopus 로고
    • Heparin-conjugated polyethyleneimine for gene delivery
    • Jeon O, Yang HS, Lee TJ and Kim BS: Heparin-conjugated polyethyleneimine for gene delivery. J Control Release 132: 236-242, 2008.
    • (2008) J Control Release , vol.132 , pp. 236-242
    • Jeon, O.1    Yang, H.S.2    Lee, T.J.3    Kim, B.S.4
  • 32
    • 84862907918 scopus 로고    scopus 로고
    • Efficient inhibition of an intraperitoneal xenograft model of human ovarian cancer by HSulf-1 gene delivered by biodegradable cationic heparin-polyethyleneimine nanogels
    • Liu P, Gou ML, Yi T, Xie C, Qi XR, Zhou ST, Deng HX, Wei YQ and Zhao X: Efficient inhibition of an intraperitoneal xenograft model of human ovarian cancer by HSulf-1 gene delivered by biodegradable cationic heparin- polyethyleneimine nanogels. Oncol Rep 27: 363-370, 2012.
    • (2012) Oncol Rep , vol.27 , pp. 363-370
    • Liu, P.1    Gou, M.L.2    Yi, T.3    Xie, C.4    Qi, X.R.5    Zhou, S.T.6    Deng, H.X.7    Wei, Y.Q.8    Zhao, X.9
  • 33
    • 38549149793 scopus 로고    scopus 로고
    • Dynamic progression of an intraperitoneal xenograft model of human ovarian cancer and its potential for preclinical trials
    • Lin XJ, Chen XC, Wang L, Wei YQ, Kan B, Wen YJ, He X and Zhao X: Dynamic progression of an intraperitoneal xenograft model of human ovarian cancer and its potential for preclinical trials. J Exp Clin Cancer Res 26: 467-474, 2007.
    • (2007) J Exp Clin Cancer Res , vol.26 , pp. 467-474
    • Lin, X.J.1    Chen, X.C.2    Wang, L.3    Wei, Y.Q.4    Kan, B.5    Wen, Y.J.6    He, X.7    Zhao, X.8
  • 34
    • 0030865849 scopus 로고    scopus 로고
    • A highly sensitive model for quantification of in vivo tumor angiogenesis induced by alginate-encapsulated tumor cells
    • Hoffmann J, Schirner M, Menrad A and Schneider MR: A highly sensitive model for quantification of in vivo tumor angiogenesis induced by alginate-encapsulated tumor cells. Cancer Res 57: 3847-3851, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3847-3851
    • Hoffmann, J.1    Schirner, M.2    Menrad, A.3    Schneider, M.R.4
  • 36
    • 0036840759 scopus 로고    scopus 로고
    • Vascular endothelial growth factor immunoneutralization plus paclitaxel markedly reduces tumor burden and ascites in athymic mouse model of ovarian cancer
    • Hu L, Hofmann J, Zaloudek C, Ferrara N, Hamilton T and Jaffe RB: Vascular endothelial growth factor immunoneutralization plus paclitaxel markedly reduces tumor burden and ascites in athymic mouse model of ovarian cancer. Am J Pathol 161: 1917-1924, 2002.
    • (2002) Am J Pathol , vol.161 , pp. 1917-1924
    • Hu, L.1    Hofmann, J.2    Zaloudek, C.3    Ferrara, N.4    Hamilton, T.5    Jaffe, R.B.6
  • 37
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82: 4-6, 1990.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 38
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P and Jain RK: Angiogenesis in cancer and other diseases. Nature 407: 249-257, 2000.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 39
    • 0034087691 scopus 로고    scopus 로고
    • Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
    • Klement G, Baruchel S, Rak J, Man S, Clark K, Hicklin DJ, Bohlen P and Kerbel RS: Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J Clin Invest 105: R15-R24, 2000.
    • (2000) J Clin Invest , vol.105
    • Klement, G.1    Baruchel, S.2    Rak, J.3    Man, S.4    Clark, K.5    Hicklin, D.J.6    Bohlen, P.7    Kerbel, R.S.8
  • 40
    • 20344367537 scopus 로고    scopus 로고
    • Tumour vascular targeting
    • Neri D and Bicknell R: Tumour vascular targeting. Nat Rev Cancer 5: 436-446, 2005.
    • (2005) Nat Rev Cancer , vol.5 , pp. 436-446
    • Neri, D.1    Bicknell, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.