Profiling the expression pattern of GPI transamidase complex subunits in human cancer

Modern Pathology

Volumn 21, Issue 8, 2008, Pages 979-991

  Nagpal, Jatin K ^a   Dasgupta, Santanu ^a   Jadallah, Sana ^a   Chae, Young K ^a   Ratovitski, Edward A ^a   Toubaji, Antoun ^a   Netto, George J ^a   Eagle, Toby ^a   Nissan, Aviram ^b   Sidransky, David ^a   Trink, Barry ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Cancer; Gene expression; GPIT complex

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; MESSENGER RNA; SMALL INTERFERING RNA;

ARTICLE; BLADDER CANCER; BREAST CANCER; CELL INVASION; CELL PROLIFERATION; DEREGULATION; GENE; GENE OVEREXPRESSION; GP18 GENE; GPAA1 GENE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; LYMPHOMA; ONCOGENE; OVARY; PIG S GENE; PIG T GENE; PIG U GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE MICROARRAY; UTERUS;

ACYLTRANSFERASES; CELL PROLIFERATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; NEOPLASM INVASIVENESS; NEOPLASMS;

EID: 48749096218     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2008.76     Document Type: Article

References (21)

1. Orlean P, Menon AK. GPI anchoring of protein in yeast and mammalian cells or: how we learned to stop worrying and love glycophospholipids. J Lipid Res 2007;48:993-1011.
2. Hamburger D, Egerton M, Riezman H. Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins. J Cell Biol 1995;129:629-639.
3. Benghezal M, Benachour A, Rusconi S, et al. Yeast Gpi8p is essential for GPI anchor attachment onto proteins. EMBO J 1996;15:6575-6583.
4. Ohishi K, Inoue N, Maeda Y, et al. Gaa1p and Gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins. Mol Biol Cell 2000;11:1523-1533.
5. Ohishi K, Inoue N, Kinoshita T. PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8. EMBO J 2001;20:4088-4098.
6. Hong Y, Ohishi K, Kang JY, et al. Human PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins. Mol Biol Cell 2003;14:1780-1789.
7. Nagamune K, Ohishi K, Ashida H, et al. GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunits. Proc Natl Acad Sci USA 2003;100:10682-10687.
8. Guo Z, Linn JF, Wu G, et al. CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer. Nat Med 2004;10:374-381.
9. Wu G, Guo Z, Chatterjee A, et al. Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer. Cancer Res 2006;66:9829-9836.
10. Kurokawa Y, Matoba R, Nakamori S, et al. PCR-array gene expression profiling of hepatocellular carcinoma. J Exp Clin Cancer Res 2004;23:135-141.
11. Ho JC, Cheung ST, Patil M, et al. Increased expression of glycosyl-phosphatidylinositol anchor attachment protein 1 (GPAA1) is associated with gene amplification in hepatocellular carcinoma. Int J Cancer 2006;119:1330-1337.
12. Yu J, Nagarajan S, Knez JJ, et al. The affected gene underlying the class K surface protein defects codes for the GPI-transamidase. Proc Natl Acad Sci USA 1997;94:12580-12585.
13. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley Jr BW, et al. Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-Beta 1 secreted by the tumor cells. J Cell Biochem 2006;97:1036-1051.
14. Hyman E, Kauraniemi P, Hautaniemi S, et al. Impact of DNA amplification on gene expression patterns in breast cancer. Cancer Res 2002;62:6240-6245.
15. Osterberg L, Levan K, Partheen K, et al. Cytogenetic analysis of Carboplatin resistance in early-stage epithelial ovarian carcinoma. Cancer Genet Cytogenet 2005;163:44-150.
16. Pere H, Tapper J, Wahlström T, et al. Distinct chromosomal imbalances in uterine serous and endometrioid carcinomas. Cancer Res 1998;58:892-895.
17. Wilting SM, Snijders PJ, Meijer GA, et al. Increased gene copy numbers at chromosome 20q are frequent in both squamous cell carcinomas and adenocarcinomas of the cervix. J Pathol 2006;209:220-230.
18. Haiman CA, Patterson N, Freedman ML, et al. Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet 2007;39:638-644.
19. Hunter DJ, Kraft P, Jacobs KB, et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet 2007;39:645-649.
20. Wreesmann VB, Ghossein RA, Patel SG, et al. Genome-wide appraisal of thyroid cancer progression. Am J Pathol 2002;161:1549-1556.
21. Luk C, Tsao MS, Bayani J, et al. Molecular cytogenetic analysis of non-small cell lung carcinoma by spectral karyotyping and comparative genomic hybridization. Cancer Genet Cytogenet 2001;125:87-99.