Liquid chromatography-tandem mass spectrometry method for simultaneous determination of seven commonly used anticancer drugs in human plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 906, Issue , 2012, Pages 1-8

  Zhou, Jingya ^a   Gao, Shouhong ^a   Zhang, Feng ^a   Jiang, Bo ^a   Zhan, Qin ^a   Cai, Fei ^a   Li, Jingxian ^a   Chen, Wansheng ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Anticancer drug; Human plasma; Liquid chromatography tandem mass spectroscopy

Indexed keywords

AMMONIUM ACETATE; ANALYTES; ANTICANCER DRUG; ATLANTIS; CANCER PATIENTS; CARBOPLATIN; CLINICAL SAMPLES; CONCENTRATION RANGES; ETOPOSIDE; EXTRACTION METHOD; GEMCITABINE; HUMAN PLASMAS; IFOSFAMIDE; IRINOTECAN; LC-MS/MS; LINEAR COEFFICIENTS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MASS SPECTROSCOPY; MOBILE PHASE; POSITIVE ELECTROSPRAY IONIZATION; RELATIVE STANDARD DEVIATIONS; SIMULTANEOUS DETERMINATIONS;

ACETONITRILE; AMMONIUM COMPOUNDS; ELECTROSPRAY IONIZATION; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA (HUMAN);

DRUG PRODUCTS;

ACETONITRILE; AMMONIUM ACETATE; CARBOPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; FORMIC ACID; GEMCITABINE; IFOSFAMIDE; IRINOTECAN; PEMETREXED; WATER;

ARTICLE; DRUG DETERMINATION; DRUG ISOLATION; ELECTROSPRAY; FLOW RATE; HUMAN; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, LIQUID; DRUG MONITORING; DRUG STABILITY; FEMALE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; NEOPLASMS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84866505327     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.07.033     Document Type: Article

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