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Volumn 7, Issue 9, 2012, Pages

Broad and Cross-Clade CD4+ T-Cell Responses Elicited by a DNA Vaccine Encoding Highly Conserved and Promiscuous HIV-1 M-Group Consensus Peptides

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; GAG PROTEIN; GAMMA INTERFERON; HLA DP ANTIGEN; HLA DQ ANTIGEN; HLA DR ANTIGEN; NEF PROTEIN; PEPTIDE; POL PROTEIN; REV PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VIF PROTEIN; VPR PROTEIN; VPU PROTEIN;

EID: 84866503033     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045267     Document Type: Article
Times cited : (25)

References (72)
  • 1
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
    • Buchbinder SP, Mehrotra DV, Duerr A, Fitzgerald DW, Mogg R, et al. (2008) Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 372: 1881-1893.
    • (2008) Lancet , vol.372 , pp. 1881-1893
    • Buchbinder, S.P.1    Mehrotra, D.V.2    Duerr, A.3    Fitzgerald, D.W.4    Mogg, R.5
  • 3
    • 77958490167 scopus 로고    scopus 로고
    • Induction of Immunity to Human Immunodeficiency Virus Type-1 by Vaccination
    • McElrath MJ, Haynes BF, (2010) Induction of Immunity to Human Immunodeficiency Virus Type-1 by Vaccination. Immunity 33: 542-554.
    • (2010) Immunity , vol.33 , pp. 542-554
    • McElrath, M.J.1    Haynes, B.F.2
  • 4
    • 79957618772 scopus 로고    scopus 로고
    • Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
    • Hansen SG, Ford JC, Lewis MS, Ventura AB, Hughes CM, et al. (2011) Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine. Nature 473: 523-U270.
    • (2011) Nature , vol.473
    • Hansen, S.G.1    Ford, J.C.2    Lewis, M.S.3    Ventura, A.B.4    Hughes, C.M.5
  • 5
    • 58149136160 scopus 로고    scopus 로고
    • Post-Step modifications for research on HIV vaccines
    • Corey L, McElrath MJ, Kublin JG, (2009) Post-Step modifications for research on HIV vaccines. Aids 23: 3-8.
    • (2009) Aids , vol.23 , pp. 3-8
    • Corey, L.1    McElrath, M.J.2    Kublin, J.G.3
  • 6
    • 67449101823 scopus 로고    scopus 로고
    • Vaccine-Induced Cellular Responses Control Simian Immunodeficiency Virus Replication after Heterologous Challenge
    • Wilson NA, Keele BF, Reed JS, Piaskowski SM, MacNair CE, et al. (2009) Vaccine-Induced Cellular Responses Control Simian Immunodeficiency Virus Replication after Heterologous Challenge. Journal of Virology 83: 6508-6521.
    • (2009) Journal of Virology , vol.83 , pp. 6508-6521
    • Wilson, N.A.1    Keele, B.F.2    Reed, J.S.3    Piaskowski, S.M.4    MacNair, C.E.5
  • 7
    • 61949216736 scopus 로고    scopus 로고
    • Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge
    • Hansen SG, Vieville C, Whizin N, Coyne-Johnson L, Siess DC, et al. (2009) Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nature Medicine 15: 293-299.
    • (2009) Nature Medicine , vol.15 , pp. 293-299
    • Hansen, S.G.1    Vieville, C.2    Whizin, N.3    Coyne-Johnson, L.4    Siess, D.C.5
  • 8
    • 29644446139 scopus 로고    scopus 로고
    • Improved vaccine protection from simian AIDS by the addition of nonstructural simian immunodeficiency virus genes
    • Hel Z, Tsai WP, Tryniszewska E, Nacsa J, Markham PD, et al. (2006) Improved vaccine protection from simian AIDS by the addition of nonstructural simian immunodeficiency virus genes. Journal of Immunology 176: 85-96.
    • (2006) Journal of Immunology , vol.176 , pp. 85-96
    • Hel, Z.1    Tsai, W.P.2    Tryniszewska, E.3    Nacsa, J.4    Markham, P.D.5
  • 9
    • 58149267963 scopus 로고    scopus 로고
    • Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
    • Liu JY, O'Brien KL, Lynch DM, Simmons NL, La Porte A, et al. (2009) Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 457: 87-91.
    • (2009) Nature , vol.457 , pp. 87-91
    • Liu, J.Y.1    O'Brien, K.L.2    Lynch, D.M.3    Simmons, N.L.4    La Porte, A.5
  • 10
    • 10744230389 scopus 로고    scopus 로고
    • Development of a DNA vaccine designed to induce cytotoxic T lymphocyte responses to multiple conserved epitopes in HIV-1
    • Wilson CC, McKinney D, Anders M, MaWhinney S, Forster J, et al. (2003) Development of a DNA vaccine designed to induce cytotoxic T lymphocyte responses to multiple conserved epitopes in HIV-1. Journal of Immunology 171: 5611-5623.
    • (2003) Journal of Immunology , vol.171 , pp. 5611-5623
    • Wilson, C.C.1    McKinney, D.2    Anders, M.3    MaWhinney, S.4    Forster, J.5
  • 11
    • 0033766645 scopus 로고    scopus 로고
    • Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination
    • Barouch DH, Santra S, Schmitz JE, Kuroda MJ, Fu TM, et al. (2000) Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. Science 290: 486-492.
    • (2000) Science , vol.290 , pp. 486-492
    • Barouch, D.H.1    Santra, S.2    Schmitz, J.E.3    Kuroda, M.J.4    Fu, T.M.5
  • 12
    • 0033868431 scopus 로고    scopus 로고
    • Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection
    • Egan MA, Charini WA, Kuroda MJ, Schmitz JE, Racz P, et al. (2000) Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection. Journal of Virology 74: 7485-7495.
    • (2000) Journal of Virology , vol.74 , pp. 7485-7495
    • Egan, M.A.1    Charini, W.A.2    Kuroda, M.J.3    Schmitz, J.E.4    Racz, P.5
  • 13
    • 79955476141 scopus 로고    scopus 로고
    • HIV-specific CD4 T cells and immune control of viral replication
    • Porichis F, Kaufmann DE, (2011) HIV-specific CD4 T cells and immune control of viral replication. Current Opinion in Hiv and Aids 6: 174-180.
    • (2011) Current Opinion in Hiv and Aids , vol.6 , pp. 174-180
    • Porichis, F.1    Kaufmann, D.E.2
  • 15
    • 1642403506 scopus 로고    scopus 로고
    • Association of strong virus-specific CD4 T cell responses with efficient natural control of primary HIV-1 infection
    • Gloster SE, Newton P, Cornforth D, Lifson JD, Williams I, et al. (2004) Association of strong virus-specific CD4 T cell responses with efficient natural control of primary HIV-1 infection. Aids 18: 749-755.
    • (2004) Aids , vol.18 , pp. 749-755
    • Gloster, S.E.1    Newton, P.2    Cornforth, D.3    Lifson, J.D.4    Williams, I.5
  • 16
    • 0030665257 scopus 로고    scopus 로고
    • Vigorous HIV-1-specific CD4(+) T cell responses associated with control of viremia
    • Rosenberg ES, Billingsley JM, Caliendo AM, Boswell SL, Sax PE, et al. (1997) Vigorous HIV-1-specific CD4(+) T cell responses associated with control of viremia. Science 278: 1447-1450.
    • (1997) Science , vol.278 , pp. 1447-1450
    • Rosenberg, E.S.1    Billingsley, J.M.2    Caliendo, A.M.3    Boswell, S.L.4    Sax, P.E.5
  • 17
    • 67650866563 scopus 로고    scopus 로고
    • Strong Ability of Nef-Specific CD4(+) Cytotoxic T Cells To Suppress Human Immunodeficiency Virus Type 1 (HIV-1) Replication in HIV-1-Infected CD4(+) T Cells and Macrophages
    • Zheng N, Fujiwara M, Ueno T, Oka S, Takiguchi M, (2009) Strong Ability of Nef-Specific CD4(+) Cytotoxic T Cells To Suppress Human Immunodeficiency Virus Type 1 (HIV-1) Replication in HIV-1-Infected CD4(+) T Cells and Macrophages. Journal of Virology 83: 7668-7677.
    • (2009) Journal of Virology , vol.83 , pp. 7668-7677
    • Zheng, N.1    Fujiwara, M.2    Ueno, T.3    Oka, S.4    Takiguchi, M.5
  • 19
    • 52649177196 scopus 로고    scopus 로고
    • Reduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8(+) T cells induced by vaccination during CD4(+) T-cell deficiency
    • Vaccari M, Mattapallil J, Song K, Tsai WP, Hryniewicz A, et al. (2008) Reduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8(+) T cells induced by vaccination during CD4(+) T-cell deficiency. Journal of Virology 82: 9629-9638.
    • (2008) Journal of Virology , vol.82 , pp. 9629-9638
    • Vaccari, M.1    Mattapallil, J.2    Song, K.3    Tsai, W.P.4    Hryniewicz, A.5
  • 20
    • 33751509716 scopus 로고    scopus 로고
    • Induction of a virus-specific effector-memory CD4(+) T cell response by attenuated SIV infection
    • Gauduin MC, Yu Y, Barabasz A, Carville A, Piatak M, et al. (2006) Induction of a virus-specific effector-memory CD4(+) T cell response by attenuated SIV infection. Journal of Experimental Medicine 203: 2661-2672.
    • (2006) Journal of Experimental Medicine , vol.203 , pp. 2661-2672
    • Gauduin, M.C.1    Yu, Y.2    Barabasz, A.3    Carville, A.4    Piatak, M.5
  • 21
    • 0037189323 scopus 로고    scopus 로고
    • AIDS - Diversity considerations in HIV-1 vaccine selection
    • Gaschen B, Taylor J, Yusim K, Foley B, Gao F, et al. (2002) AIDS- Diversity considerations in HIV-1 vaccine selection. Science 296: 2354-2360.
    • (2002) Science , vol.296 , pp. 2354-2360
    • Gaschen, B.1    Taylor, J.2    Yusim, K.3    Foley, B.4    Gao, F.5
  • 23
    • 33745771090 scopus 로고    scopus 로고
    • Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group M consensus env immunogen
    • Weaver EA, Lu ZJ, Camacho ZT, Moukdar F, Liao HX, et al. (2006) Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group M consensus env immunogen. Journal of Virology 80: 6745-6756.
    • (2006) Journal of Virology , vol.80 , pp. 6745-6756
    • Weaver, E.A.1    Lu, Z.J.2    Camacho, Z.T.3    Moukdar, F.4    Liao, H.X.5
  • 25
    • 37349054681 scopus 로고    scopus 로고
    • Rational design of a multiepitope vaccine encoding T-Lymphocyte epitopes for treatment of chronic hepatitis B virus infections
    • Depla E, Van der Aa A, Livingston BD, Crimi C, Allosery K, et al. (2008) Rational design of a multiepitope vaccine encoding T-Lymphocyte epitopes for treatment of chronic hepatitis B virus infections. Journal of Virology 82: 435-450.
    • (2008) Journal of Virology , vol.82 , pp. 435-450
    • Depla, E.1    van der Aa, A.2    Livingston, B.D.3    Crimi, C.4    Allosery, K.5
  • 26
    • 79960644754 scopus 로고    scopus 로고
    • ImMucin: A novel therapeutic vaccine with promiscuous MHC binding for the treatment of MUC1-expressing tumors
    • Kovjazin R, Volovitz I, Kundel Y, Rosenbaum E, Medalia G, et al. (2011) ImMucin: A novel therapeutic vaccine with promiscuous MHC binding for the treatment of MUC1-expressing tumors. Vaccine 29: 4676-4686.
    • (2011) Vaccine , vol.29 , pp. 4676-4686
    • Kovjazin, R.1    Volovitz, I.2    Kundel, Y.3    Rosenbaum, E.4    Medalia, G.5
  • 27
    • 34247597291 scopus 로고    scopus 로고
    • Determination of a HLA II promiscuous peptide cocktail as potential vaccine against EBV latency II malignancies
    • Depil S, Morales O, Castelli FA, Delhem N, Francois V, et al. (2007) Determination of a HLA II promiscuous peptide cocktail as potential vaccine against EBV latency II malignancies. Journal of Immunotherapy 30: 215-226.
    • (2007) Journal of Immunotherapy , vol.30 , pp. 215-226
    • Depil, S.1    Morales, O.2    Castelli, F.A.3    Delhem, N.4    Francois, V.5
  • 28
    • 77950819099 scopus 로고    scopus 로고
    • T-Cell Correlates of Vaccine Efficacy after a Heterologous Simian Immunodeficiency Virus Challenge
    • Martins MA, Wilson NA, Reed JS, Ahn CD, Klimentidis YC, et al. (2010) T-Cell Correlates of Vaccine Efficacy after a Heterologous Simian Immunodeficiency Virus Challenge. Journal of Virology 84: 4352-4365.
    • (2010) Journal of Virology , vol.84 , pp. 4352-4365
    • Martins, M.A.1    Wilson, N.A.2    Reed, J.S.3    Ahn, C.D.4    Klimentidis, Y.C.5
  • 30
    • 77954652466 scopus 로고    scopus 로고
    • Combined Env- and Gag-specific T cell responses in relation to programmed death-1 receptor and CD4+T cell loss rates in human immunodeficiency virus-1 infection
    • Pettersen FO, Tasken K, Kvale D, (2010) Combined Env- and Gag-specific T cell responses in relation to programmed death-1 receptor and CD4+T cell loss rates in human immunodeficiency virus-1 infection. Clinical and Experimental Immunology 161: 315-323.
    • (2010) Clinical and Experimental Immunology , vol.161 , pp. 315-323
    • Pettersen, F.O.1    Tasken, K.2    Kvale, D.3
  • 31
    • 84855927062 scopus 로고    scopus 로고
    • HIV-Specific CD4 T Cell Responses to Different Viral Proteins Have Discordant Associations with Viral Load and Clinical Outcome
    • Ranasinghe S, Flanders M, Cutler S, Soghoian DZ, Ghebremichael M, et al. (2012) HIV-Specific CD4 T Cell Responses to Different Viral Proteins Have Discordant Associations with Viral Load and Clinical Outcome. Journal of Virology 86: 277-283.
    • (2012) Journal of Virology , vol.86 , pp. 277-283
    • Ranasinghe, S.1    Flanders, M.2    Cutler, S.3    Soghoian, D.Z.4    Ghebremichael, M.5
  • 32
    • 77956217622 scopus 로고    scopus 로고
    • A Vaccine Encoding Conserved Promiscuous HIV CD4 Epitopes Induces Broad T Cell Responses in Mice Transgenic to Multiple Common HLA Class II Molecules
    • Ribeiro SP, Rosa DS, Fonseca SG, Mairena EC, Postol E, et al. (2010) A Vaccine Encoding Conserved Promiscuous HIV CD4 Epitopes Induces Broad T Cell Responses in Mice Transgenic to Multiple Common HLA Class II Molecules. Plos One 5.
    • (2010) Plos One , pp. 5
    • Ribeiro, S.P.1    Rosa, D.S.2    Fonseca, S.G.3    Mairena, E.C.4    Postol, E.5
  • 33
    • 79951816846 scopus 로고    scopus 로고
    • A DNA Vaccine Encoding Multiple HIV CD4 Epitopes Elicits Vigorous Polyfunctional, Long-Lived CD4(+) and CD8(+) T Cell Responses
    • Rosa DS, Ribeiro SP, Almeida RR, Mairena EC, Postol E, et al. (2011) A DNA Vaccine Encoding Multiple HIV CD4 Epitopes Elicits Vigorous Polyfunctional, Long-Lived CD4(+) and CD8(+) T Cell Responses. Plos One 6.
    • (2011) Plos One , pp. 6
    • Rosa, D.S.1    Ribeiro, S.P.2    Almeida, R.R.3    Mairena, E.C.4    Postol, E.5
  • 34
    • 0033021020 scopus 로고    scopus 로고
    • Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices
    • Sturniolo T, Bono E, Ding JY, Raddrizzani L, Tuereci O, et al. (1999) Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices. Nature Biotechnology 17: 555-561.
    • (1999) Nature Biotechnology , vol.17 , pp. 555-561
    • Sturniolo, T.1    Bono, E.2    Ding, J.Y.3    Raddrizzani, L.4    Tuereci, O.5
  • 35
    • 0036569585 scopus 로고    scopus 로고
    • Identification of HLA DR7-restricted epitopes from human telomerase reverse transcriptase recognized by CD4+T-helper cells
    • Schroers R, Huang XF, Hammer J, Zhang JW, Chen SY, (2002) Identification of HLA DR7-restricted epitopes from human telomerase reverse transcriptase recognized by CD4+T-helper cells. Cancer Research 62: 2600-2605.
    • (2002) Cancer Research , vol.62 , pp. 2600-2605
    • Schroers, R.1    Huang, X.F.2    Hammer, J.3    Zhang, J.W.4    Chen, S.Y.5
  • 36
    • 0033566811 scopus 로고    scopus 로고
    • Cutting edge: Identification of novel T cell epitopes in Lol p5a by computational prediction
    • de Lalla C, Sturniolo T, Abbruzzese L, Hammer J, Sidoli A, et al. (1999) Cutting edge: Identification of novel T cell epitopes in Lol p5a by computational prediction. Journal of Immunology 163: 1725-1729.
    • (1999) Journal of Immunology , vol.163 , pp. 1725-1729
    • de Lalla, C.1    Sturniolo, T.2    Abbruzzese, L.3    Hammer, J.4    Sidoli, A.5
  • 37
    • 33748368696 scopus 로고    scopus 로고
    • Immunogenicity of a recombinant protein containing the Plasmodium vivax vaccine candidate MSP1(19) and two human CD4(+) T-cell epitopes administered to non-human primates (Callithrix jacchus jacchus)
    • Rosa DS, Iwai LK, Tzelepis F, Bargieri DY, Medeiros MA, et al. (2006) Immunogenicity of a recombinant protein containing the Plasmodium vivax vaccine candidate MSP1(19) and two human CD4(+) T-cell epitopes administered to non-human primates (Callithrix jacchus jacchus). Microbes and Infection 8: 2130-2137.
    • (2006) Microbes and Infection , vol.8 , pp. 2130-2137
    • Rosa, D.S.1    Iwai, L.K.2    Tzelepis, F.3    Bargieri, D.Y.4    Medeiros, M.A.5
  • 38
    • 34248384422 scopus 로고    scopus 로고
    • T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals
    • Iwai LK, Yoshida M, Sadahiro A, da Silva WR, Marin ML, et al. (2007) T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals. Clinical and Vaccine Immunology 14: 474-476.
    • (2007) Clinical and Vaccine Immunology , vol.14 , pp. 474-476
    • Iwai, L.K.1    Yoshida, M.2    Sadahiro, A.3    da Silva, W.R.4    Marin, M.L.5
  • 39
    • 7944224384 scopus 로고    scopus 로고
    • Discovery of promiscuous HLA-II-restricted T cell epitopes with TEPITOPE
    • Bian HJ, Hammer J, (2004) Discovery of promiscuous HLA-II-restricted T cell epitopes with TEPITOPE. Methods 34: 468-475.
    • (2004) Methods , vol.34 , pp. 468-475
    • Bian, H.J.1    Hammer, J.2
  • 40
    • 3042700384 scopus 로고    scopus 로고
    • In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitized individuals
    • Iwai LK, Yoshida M, Sidney J, Shikanai-Yasuda MA, Goldberg AC, et al. (2003) In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitized individuals. Molecular Medicine 9: 209-219.
    • (2003) Molecular Medicine , vol.9 , pp. 209-219
    • Iwai, L.K.1    Yoshida, M.2    Sidney, J.3    Shikanai-Yasuda, M.A.4    Goldberg, A.C.5
  • 42
    • 0036604410 scopus 로고    scopus 로고
    • A rational strategy to design multiepitope immunogens based on multiple th lymphocyte epitopes
    • Livingston B, Crimi C, Newman M, Higashimoto Y, Appella E, et al. (2002) A rational strategy to design multiepitope immunogens based on multiple th lymphocyte epitopes. Journal of Immunology 168: 5499-5506.
    • (2002) Journal of Immunology , vol.168 , pp. 5499-5506
    • Livingston, B.1    Crimi, C.2    Newman, M.3    Higashimoto, Y.4    Appella, E.5
  • 43
    • 66149144807 scopus 로고    scopus 로고
    • High Human Herpesvirus 8 (HHV-8) Prevalence, Clinical Correlates and High Incidence among Recently HIV-1-Infected Subjects in Sao Paulo, Brazil
    • Batista MD, Ferreira S, Sauer MM, Tomiyama H, Maidana Giret MT, et al. (2009) High Human Herpesvirus 8 (HHV-8) Prevalence, Clinical Correlates and High Incidence among Recently HIV-1-Infected Subjects in Sao Paulo, Brazil. Plos One 4.
    • (2009) Plos One , pp. 4
    • Batista, M.D.1    Ferreira, S.2    Sauer, M.M.3    Tomiyama, H.4    Maidana Giret, M.T.5
  • 44
    • 25144497593 scopus 로고    scopus 로고
    • Establishment of the serologic testing algorithm for recent human immunodeficiency virus (HIV) seroconversion (STARHS) strategy in the city of São Paulo, Brazil
    • Oliveira
    • Kallas EG, Bassichetto KC, Oliveira (2004) Establishment of the serologic testing algorithm for recent human immunodeficiency virus (HIV) seroconversion (STARHS) strategy in the city of São Paulo, Brazil. The Brazilian Journal of Infectious Diseases 8: 8.
    • (2004) The Brazilian Journal of Infectious Diseases , vol.8 , pp. 8
    • Kallas, E.G.1    Bassichetto, K.C.2
  • 45
    • 35348833716 scopus 로고    scopus 로고
    • Characterization of the full-length human immunodeficiency virus-1 genome from recently infected subjects in Brazil
    • Sa-Filho D, Kallas EG, Sanabani S, Sabino E, Sucupira MC, et al. (2007) Characterization of the full-length human immunodeficiency virus-1 genome from recently infected subjects in Brazil. Aids Research and Human Retroviruses 23: 1087-1094.
    • (2007) Aids Research and Human Retroviruses , vol.23 , pp. 1087-1094
    • Sa-Filho, D.1    Kallas, E.G.2    Sanabani, S.3    Sabino, E.4    Sucupira, M.C.5
  • 46
    • 80054700479 scopus 로고    scopus 로고
    • Characterization of Partial and Near Full-Length Genomes of HIV-1 Strains Sampled from Recently Infected Individuals in Sao Paulo, Brazil
    • Sanabani SS, de Souza Pastena ER, da Costa AC, Martinez VP, Kleine-Neto W, et al. (2011) Characterization of Partial and Near Full-Length Genomes of HIV-1 Strains Sampled from Recently Infected Individuals in Sao Paulo, Brazil. Plos One 6.
    • (2011) Plos One , pp. 6
    • Sanabani, S.S.1    de Souza Pastena, E.R.2    da Costa, A.C.3    Martinez, V.P.4    Kleine-Neto, W.5
  • 47
    • 33745855139 scopus 로고    scopus 로고
    • Evaluation of the interlaboratory concordance in quantification of human immunodeficiency virus-specific T cells with a gamma interferon enzyme-linked immunospot assay
    • Samri A, Durier C, Urrutia A, Sanchez I, Gahery-Segard H, et al. (2006) Evaluation of the interlaboratory concordance in quantification of human immunodeficiency virus-specific T cells with a gamma interferon enzyme-linked immunospot assay. Clinical and Vaccine Immunology 13: 684-697.
    • (2006) Clinical and Vaccine Immunology , vol.13 , pp. 684-697
    • Samri, A.1    Durier, C.2    Urrutia, A.3    Sanchez, I.4    Gahery-Segard, H.5
  • 48
    • 37649021448 scopus 로고    scopus 로고
    • Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester
    • Quah BJC, Warren HS, Parish CR, (2007) Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester. Nature Protocols 2: 2049-2056.
    • (2007) Nature Protocols , vol.2 , pp. 2049-2056
    • Quah, B.J.C.1    Warren, H.S.2    Parish, C.R.3
  • 49
    • 44449141311 scopus 로고    scopus 로고
    • Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort
    • Lacap PA, Huntington JD, Luo M, Nagelkerke NJD, Bielawny T, et al. (2008) Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort. Aids 22: 1029-1038.
    • (2008) Aids , vol.22 , pp. 1029-1038
    • Lacap, P.A.1    Huntington, J.D.2    Luo, M.3    Nagelkerke, N.J.D.4    Bielawny, T.5
  • 50
    • 77957944425 scopus 로고    scopus 로고
    • HIV Controllers with HLA-DRB1*13 and HLA-DQB1*06 Alleles Have Strong, Polyfunctional Mucosal CD4(+) T-Cell Responses
    • Ferre AL, Hunt PW, McConnell DH, Morris MM, Garcia JC, et al. (2010) HIV Controllers with HLA-DRB1*13 and HLA-DQB1*06 Alleles Have Strong, Polyfunctional Mucosal CD4(+) T-Cell Responses. Journal of Virology 84: 11020-11029.
    • (2010) Journal of Virology , vol.84 , pp. 11020-11029
    • Ferre, A.L.1    Hunt, P.W.2    McConnell, D.H.3    Morris, M.M.4    Garcia, J.C.5
  • 51
    • 33751242462 scopus 로고    scopus 로고
    • Identification of novel consensus CD4 T-cell epitopes from clade B HIV-1 whole genome that are frequently recognized by HIV-1 infected patients
    • Fonseca SG, Coutinho-Silva A, Fonseca LAM, Segurado AC, Moraes SL, et al. (2006) Identification of novel consensus CD4 T-cell epitopes from clade B HIV-1 whole genome that are frequently recognized by HIV-1 infected patients. Aids 20: 2263-2273.
    • (2006) Aids , vol.20 , pp. 2263-2273
    • Fonseca, S.G.1    Coutinho-Silva, A.2    Fonseca, L.A.M.3    Segurado, A.C.4    Moraes, S.L.5
  • 52
    • 33645028090 scopus 로고    scopus 로고
    • Group M-based HIV-1 Gag peptides are frequently targeted by T cells in chronically infected US and Zambian patients
    • Bansal A, Gough E, Ritter D, Wilson C, Mulenga J, et al. (2006) Group M-based HIV-1 Gag peptides are frequently targeted by T cells in chronically infected US and Zambian patients. Aids 20: 353-360.
    • (2006) Aids , vol.20 , pp. 353-360
    • Bansal, A.1    Gough, E.2    Ritter, D.3    Wilson, C.4    Mulenga, J.5
  • 53
    • 38449106129 scopus 로고    scopus 로고
    • CD8(+) CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity
    • Bijker MS, van den Eeden SJF, Franken KL, Melief CJM, Offringa R, et al. (2007) CD8(+) CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity. Journal of Immunology 179: 5033-5040.
    • (2007) Journal of Immunology , vol.179 , pp. 5033-5040
    • Bijker, M.S.1    van den Eeden, S.J.F.2    Franken, K.L.3    Melief, C.J.M.4    Offringa, R.5
  • 54
    • 22144458334 scopus 로고    scopus 로고
    • PREDBALB/c: a system for the prediction of peptide binding to H2(d) molecules, a haplotype of the BALB/c mouse
    • Zhang GL, Srinivasan KN, Veeramani A, August JT, Brusic V, (2005) PREDBALB/c: a system for the prediction of peptide binding to H2(d) molecules, a haplotype of the BALB/c mouse. Nucleic Acids Research 33: W180-W183.
    • (2005) Nucleic Acids Research , vol.33
    • Zhang, G.L.1    Srinivasan, K.N.2    Veeramani, A.3    August, J.T.4    Brusic, V.5
  • 55
    • 0042890384 scopus 로고    scopus 로고
    • Identification of novel immunodominant CD4(+) Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity
    • BenMohamed L, Bertrand G, McNamara CD, Gras-Masse H, Hammer J, et al. (2003) Identification of novel immunodominant CD4(+) Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity. Journal of Virology 77: 9463-9473.
    • (2003) Journal of Virology , vol.77 , pp. 9463-9473
    • BenMohamed, L.1    Bertrand, G.2    McNamara, C.D.3    Gras-Masse, H.4    Hammer, J.5
  • 56
    • 33746689169 scopus 로고    scopus 로고
    • A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and CHIV-1 primary viruses
    • Liao H-X, Sutherland LL, Xia S-M, Brock ME, Scearce RM, et al. (2006) A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and CHIV-1 primary viruses. Virology 353: 268-282.
    • (2006) Virology , vol.353 , pp. 268-282
    • Liao, H.-X.1    Sutherland, L.L.2    Xia, S.-M.3    Brock, M.E.4    Scearce, R.M.5
  • 57
    • 0038515116 scopus 로고    scopus 로고
    • Polytope vaccines for the codelivery of multiple CD8T-cell epitopes
    • Suhrbier A, (2002) Polytope vaccines for the codelivery of multiple CD8T-cell epitopes. Expert Review of Vaccines 1: 207-213.
    • (2002) Expert Review of Vaccines , vol.1 , pp. 207-213
    • Suhrbier, A.1
  • 58
    • 0033120573 scopus 로고    scopus 로고
    • Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes
    • Ishioka GY, Fikes J, Hermanson G, Livingston B, Crimi C, et al. (1999) Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes. Journal of Immunology 162: 3915-3925.
    • (1999) Journal of Immunology , vol.162 , pp. 3915-3925
    • Ishioka, G.Y.1    Fikes, J.2    Hermanson, G.3    Livingston, B.4    Crimi, C.5
  • 59
    • 34249911224 scopus 로고    scopus 로고
    • Immunogenicity of hybrid DNA vaccines expressing hepatitis B core particles carrying human and simian immunodeficiency virus epitopes in mice and rhesus macaques
    • Fuller DH, Shipley T, Allen TM, Fuller JT, Wu MS, et al. (2007) Immunogenicity of hybrid DNA vaccines expressing hepatitis B core particles carrying human and simian immunodeficiency virus epitopes in mice and rhesus macaques. Virology 364: 245-255.
    • (2007) Virology , vol.364 , pp. 245-255
    • Fuller, D.H.1    Shipley, T.2    Allen, T.M.3    Fuller, J.T.4    Wu, M.S.5
  • 60
    • 38149018633 scopus 로고    scopus 로고
    • Targeting of a CD8 T cell Env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure
    • Ngumbela KC, Day CL, Mncube Z, Nair K, Ramduth D, et al. (2008) Targeting of a CD8 T cell Env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure. Aids Research and Human Retroviruses 24: 72-82.
    • (2008) Aids Research and Human Retroviruses , vol.24 , pp. 72-82
    • Ngumbela, K.C.1    Day, C.L.2    Mncube, Z.3    Nair, K.4    Ramduth, D.5
  • 61
    • 33846101731 scopus 로고    scopus 로고
    • CD8(+) T-cell responses to different HIV proteins have discordant associations with viral load
    • Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, et al. (2007) CD8(+) T-cell responses to different HIV proteins have discordant associations with viral load. Nature Medicine 13: 46-53.
    • (2007) Nature Medicine , vol.13 , pp. 46-53
    • Kiepiela, P.1    Ngumbela, K.2    Thobakgale, C.3    Ramduth, D.4    Honeyborne, I.5
  • 63
    • 84862904805 scopus 로고    scopus 로고
    • Extended Follow-up Confirms Early Vaccine-Enhanced Risk of HIV Acquisition and Demonstrates Waning Effect Over Time Among Participants in a Randomized Trial of Recombinant Adenovirus HIV Vaccine (Step Study)
    • Duerr A, Huang Y, Buchbinder S, Coombs RW, Sanchez J, et al. (2012) Extended Follow-up Confirms Early Vaccine-Enhanced Risk of HIV Acquisition and Demonstrates Waning Effect Over Time Among Participants in a Randomized Trial of Recombinant Adenovirus HIV Vaccine (Step Study). Journal of Infectious Diseases 206.
    • (2012) Journal of Infectious Diseases , pp. 206
    • Duerr, A.1    Huang, Y.2    Buchbinder, S.3    Coombs, R.W.4    Sanchez, J.5
  • 64
    • 77949263061 scopus 로고    scopus 로고
    • Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys
    • Barouch DH, O'Brien KL, Simmons NL, King SL, Abbink P, et al. (2010) Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys. Nature Medicine 16: 319-U116.
    • (2010) Nature Medicine , vol.16
    • Barouch, D.H.1    O'Brien, K.L.2    Simmons, N.L.3    King, S.L.4    Abbink, P.5
  • 66
    • 78649516786 scopus 로고    scopus 로고
    • HIV-1-Specific Interleukin-21(+) CD4(+) T Cell Responses Contribute to Durable Viral Control through the Modulation of HIV-Specific CD8(+) T Cell Function
    • Chevalier MF, Juelg B, Pyo A, Flanders M, Ranasinghe S, et al. (2011) HIV-1-Specific Interleukin-21(+) CD4(+) T Cell Responses Contribute to Durable Viral Control through the Modulation of HIV-Specific CD8(+) T Cell Function. Journal of Virology 85: 733-741.
    • (2011) Journal of Virology , vol.85 , pp. 733-741
    • Chevalier, M.F.1    Juelg, B.2    Pyo, A.3    Flanders, M.4    Ranasinghe, S.5
  • 67
    • 70849099812 scopus 로고    scopus 로고
    • CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help
    • Nakanishi Y, Lu B, Gerard C, Iwasaki A, (2009) CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help. Nature 462: 510-U205.
    • (2009) Nature , vol.462
    • Nakanishi, Y.1    Lu, B.2    Gerard, C.3    Iwasaki, A.4
  • 68
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock DJ, Shen H, (2003) Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300: 337-339.
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 69
    • 34948906159 scopus 로고    scopus 로고
    • Superior control of HIV-1 replication by CD8(+) T cells is reflected by their avidity, polyfunctionality, and clonal turnover
    • Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, et al. (2007) Superior control of HIV-1 replication by CD8(+) T cells is reflected by their avidity, polyfunctionality, and clonal turnover. Journal of Experimental Medicine 204: 2473-2485.
    • (2007) Journal of Experimental Medicine , vol.204 , pp. 2473-2485
    • Almeida, J.R.1    Price, D.A.2    Papagno, L.3    Arkoub, Z.A.4    Sauce, D.5
  • 70
    • 0036884096 scopus 로고    scopus 로고
    • Presence of HIV-1 gag-specific IFN-gamma+IL-2(+) and CD28(+)IL-2(+) CD4 T cell responses is associated with nonprogression in HIV-1 infection
    • Boaz MJ, Waters A, Murad S, Easterbrook PJ, Vyakarnam A, (2002) Presence of HIV-1 gag-specific IFN-gamma+IL-2(+) and CD28(+)IL-2(+) CD4 T cell responses is associated with nonprogression in HIV-1 infection. Journal of Immunology 169: 6376-6385.
    • (2002) Journal of Immunology , vol.169 , pp. 6376-6385
    • Boaz, M.J.1    Waters, A.2    Murad, S.3    Easterbrook, P.J.4    Vyakarnam, A.5
  • 71
    • 27644489746 scopus 로고    scopus 로고
    • Phenotypic, functional, and kinetic parameters associated with a apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment
    • Emu B, Sinclair E, Favre D, Moretto WJ, Hsue P, et al. (2005) Phenotypic, functional, and kinetic parameters associated with a apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment. Journal of Virology 79: 14169-14178.
    • (2005) Journal of Virology , vol.79 , pp. 14169-14178
    • Emu, B.1    Sinclair, E.2    Favre, D.3    Moretto, W.J.4    Hsue, P.5


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