Cellular protein quality control and the evolution of aggregates in spinocerebellar ataxia type 3 (SCA3)

Neuropathology and Applied Neurobiology

Volumn 38, Issue 6, 2012, Pages 548-558

  Seidel, K ^a,b,d   Meister, M ^a,b   Dugbartey, G J ^a   Zijlstra, M P ^b   Vinet, J ^b   Brunt, E R P ^a   Van Leeuwen, F W ^c   Rub U ^d   Kampinga, H H ^b   Den Dunnen, W F A ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

DNAJ; HSPA; Protein aggregation; Protein quality control; Spinocerebellar ataxia

Indexed keywords

ANTIBODY; BIOLOGICAL MARKER; CELL PROTEIN; CHAPERONE; POLYGLUTAMINE; PROTEASOME; PROTEIN DNAJB1; PROTEIN HSPA1A; PROTEIN P62; PROTEIN UBB; UBIQUITIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AUTOPHAGOSOME; CELL NUCLEUS INCLUSION BODY; CLINICAL ARTICLE; CYTOPLASM; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NERVE DEGENERATION; NEUROPATHOLOGY; PONS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; QUALITY CONTROL; QUANTITATIVE ANALYSIS; SPINOCEREBELLAR ATAXIA TYPE 3; SPINOCEREBELLAR DEGENERATION; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; AGED, 80 AND OVER; FEMALE; HSP40 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INTRANUCLEAR INCLUSION BODIES; MACHADO-JOSEPH DISEASE; MALE; MIDDLE AGED; NEURONS; PONS; UBIQUITIN;

EID: 84866465273     PISSN: 03051846     EISSN: 13652990     Source Type: Journal    
DOI: 10.1111/j.1365-2990.2011.01220.x     Document Type: Article

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