Sirenomelia Phenotype in Bmp7;Shh Compound Mutants: A Novel Experimental Model for Studies of Caudal Body Malformations

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Garrido Allepuz, Carlos ^a   González Lamuño, Domingo ^b   Ros, Maria A ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

^b HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR 8; MESSENGER RNA; TRANSCRIPTION FACTOR MSX2; VASCULAR ENDOTHELIAL CADHERIN;

ALLELE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BMP4 GENE; BMP7 GENE; BONE DEVELOPMENT; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EXPERIMENTAL MODEL; FGF8 GENE; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE MUTATION; GENOTYPE; HEART DEVELOPMENT; HETEROZYGOTE; HOMOZYGOTE; ISL1 GENE; LIMB DEVELOPMENT; LMX1B GENE; MORPHOGENESIS; MOUSE; MSX2 GENE; NEWBORN; NONHUMAN; PATHOGENESIS; PHENOTYPE; PITX1 GENE; SHH GENE; SIRENOMELIA; TBX4 GENE;

ANIMALS; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 7; CELL DEATH; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; ECTROMELIA; EMBRYO, MAMMALIAN; GENE DELETION; HEDGEHOG PROTEINS; HUMANS; LOWER EXTREMITY; MICE; PHENOTYPE;

MUS;

EID: 84866455766     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044962     Document Type: Article

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