Safe genetic modification of cardiac stem cells using a site-specific integration technique

Circulation

Volumn 126, Issue 11 SUPPL.1, 2012, Pages

  Lan, Feng ^a,b   Liu, Junwei ^a,b   Narsinh, Kazim H ^a,b   Hu, Shijun ^a,b   Han, Leng ^a,b   Lee, Andrew S ^a,b   Karow, Marisa ^b   Nguyen, Patricia K ^a,b   Nag, Divya ^a,b   Calos, Michele P ^b   Robbins, Robert C ^b   Wu, Joseph C ^a,b  

^a Department of Medicine   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cardiovascular disease; cell therapy; imaging; stem cells

Indexed keywords

PHIC31 RECOMBINASE; RECOMBINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; CARDIAC STEM CELL; CELL DIFFERENTIATION; CELL FATE; CELL ISOLATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA MODIFICATION; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; FEMALE; FLUORESCENCE MICROSCOPY; FUSION GENE; GENE EXPRESSION PROFILING; GENETIC PROCEDURES; HEART INFARCTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; LASER DOPPLER FLOWMETRY; LIMB ISCHEMIA; LIMB PERFUSION; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLASMID; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REPORTER GENE; SITE SPECIFIC INTEGRATION TECHNIQUE; STEM CELL; STEM CELL TRANSPLANTATION;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CHROMOSOMES, HUMAN, PAIR 19; ENDOTHELIAL CELLS; FEMALE; FETAL HEART; FETAL STEM CELLS; GENE EXPRESSION REGULATION; GENES, REPORTER; GENETIC THERAPY; HINDLIMB; HUMANS; INTEGRASES; ISCHEMIA; LUCIFERASES, FIREFLY; LUMINESCENT PROTEINS; MAGNETIC RESONANCE IMAGING; MICE; MICE, SCID; MUTAGENESIS, INSERTIONAL; MYOCARDIAL INFARCTION; PROTEINS; RANDOM ALLOCATION; RECOMBINANT FUSION PROTEINS; THYMIDINE KINASE; TRANSGENES; VIRAL PROTEINS; VIRUS INTEGRATION;

EID: 84866454962     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.111.084913     Document Type: Article

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