-
1
-
-
79952394490
-
An algorithmic framework for predicting side-effects of drugs
-
Atias,N. and Sharan,R. (2011) An algorithmic framework for predicting side-effects of drugs. J. Comput. Biol., 18, 207-218.
-
(2011)
J. Comput. Biol
, vol.18
, pp. 207-218
-
-
Atias, N.1
Sharan, R.2
-
2
-
-
33846363963
-
Structure-activity relationships for in vitro and in vivo toxicity
-
Blagg,J. (2006) Structure-activity relationships for in vitro and in vivo toxicity. Annu. Rep. Med. Chem., 41, 353-368.
-
(2006)
Annu. Rep. Med. Chem
, vol.41
, pp. 353-368
-
-
Blagg, J.1
-
3
-
-
69849094133
-
Supervised prediction of drug-target interactions using bipartite local models
-
Bleakley,K. and Yamanishi,Y. (2009) Supervised prediction of drug-target interactions using bipartite local models. Bioinformatics, 25, 2397-2403.
-
(2009)
Bioinformatics
, vol.25
, pp. 2397-2403
-
-
Bleakley, K.1
Yamanishi, Y.2
-
4
-
-
47249146126
-
Drug target identification using side-effect similarity
-
Campillos,M. et al. (2008) Drug target identification using side-effect similarity. Science, 321, 263-266.
-
(2008)
Science
, vol.321
, pp. 263-266
-
-
Campillos, M.1
-
5
-
-
11144341956
-
Chemical space and biology
-
Dobson,C. (2004) Chemical space and biology. Nature, 432, 824-828.
-
(2004)
Nature
, vol.432
, pp. 824-828
-
-
Dobson, C.1
-
6
-
-
38349114038
-
Genome scale enzyme-metabolite and drug-target interaction predictions using the signature molecular descriptor
-
Faulon,J. et al. (2008) Genome scale enzyme-metabolite and drug-target interaction predictions using the signature molecular descriptor. Bioinformatics, 24, 225-233.
-
(2008)
Bioinformatics
, vol.24
, pp. 225-233
-
-
Faulon, J.1
-
7
-
-
52749085437
-
Protein-ligand interaction prediction: an improved chemogenomics approach
-
Jacob,L. and Vert,J.-P. (2008) Protein-ligand interaction prediction: an improved chemogenomics approach. Bioinformatics, 24, 2149-2156.
-
(2008)
Bioinformatics
, vol.24
, pp. 2149-2156
-
-
Jacob, L.1
Vert, J.-P.2
-
8
-
-
38549126643
-
KEGG for linking genomes to life and the environment
-
(Database issue)
-
Kanehisa,M. et al. (2008) KEGG for linking genomes to life and the environment. Nucleic Acids Res., 36(Database issue), D480-D485.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Kanehisa, M.1
-
9
-
-
33644874819
-
From genomics to chemical genomics: new developments in KEGG
-
(Database issue)
-
Kanehisa,M. et al. (2006) From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res., 34(Database issue), D354-357.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Kanehisa, M.1
-
10
-
-
70449634957
-
Predicting new molecular targets for known drugs
-
Keiser,M. et al. (2009) Predicting new molecular targets for known drugs. Nature, 462, 175-81.
-
(2009)
Nature
, vol.462
, pp. 175-81
-
-
Keiser, M.1
-
11
-
-
76149120425
-
A side effect resource to capture phenotypic effects of drugs
-
Kuhn,M. et al. (2010) A side effect resource to capture phenotypic effects of drugs. Mol. Syst. Biol., 6, 343.
-
(2010)
Mol. Syst. Biol
, vol.6
, pp. 343
-
-
Kuhn, M.1
-
12
-
-
23844458045
-
Graph kernels for molecular structure-activity relationship analysis with support vector machines
-
Mahe,P. et al. (2005) Graph kernels for molecular structure-activity relationship analysis with support vector machines. J. Chem. Inf. Model., 45, 939-951.
-
(2005)
J. Chem. Inf. Model
, vol.45
, pp. 939-951
-
-
Mahe, P.1
-
13
-
-
4444273377
-
Protein homology detection using string alignment kernels
-
Saigo,H. et al. (2004) Protein homology detection using string alignment kernels. Bioinformatics, 20, 1682-1689.
-
(2004)
Bioinformatics
, vol.20
, pp. 1682-1689
-
-
Saigo, H.1
-
14
-
-
80052068382
-
Adverse event profiles of platinum agents: data mining of the public version of the FDA adverse event reporting system, AERS, and reproducibility of clinical observations
-
Sakaeda,T. et al. (2011) Adverse event profiles of platinum agents: data mining of the public version of the FDA adverse event reporting system, AERS, and reproducibility of clinical observations. Int. J. Med. Sci., 8, 487-491.
-
(2011)
Int. J. Med. Sci
, vol.8
, pp. 487-491
-
-
Sakaeda, T.1
-
15
-
-
0034331004
-
Chemical genetics: ligand-based discovery of gene function
-
Stockwell,B. (2000) Chemical genetics: ligand-based discovery of gene function. Nat. Rev. Genet., 1, 116-125.
-
(2000)
Nat. Rev. Genet
, vol.1
, pp. 116-125
-
-
Stockwell, B.1
-
16
-
-
79959379936
-
Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels
-
Tatonetti,N. et al. (2011) Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels. Clin. Pharmacol. Ther., 90, 133-142.
-
(2011)
Clin. Pharmacol. Ther
, vol.90
, pp. 133-142
-
-
Tatonetti, N.1
-
17
-
-
84856805878
-
A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports
-
Tatonetti,N. et al. (2012) A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports. J. Am. Med. Inform. Assoc., 19, 79-85.
-
(2012)
J. Am. Med. Inform. Assoc
, vol.19
, pp. 79-85
-
-
Tatonetti, N.1
-
18
-
-
80054881553
-
Gaussian interaction profile kernels for predicting drug-target interaction
-
van Laarhoven,T. et al. (2011) Gaussian interaction profile kernels for predicting drug-target interaction. Bioinformatics, 27, 3036-3043.
-
(2011)
Bioinformatics
, vol.27
, pp. 3036-3043
-
-
van Laarhoven, T.1
-
19
-
-
26944446576
-
Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development
-
Whitebread,S. et al. (2005) Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development. Drug Discov. Today, 10, 1421-1433.
-
(2005)
Drug Discov. Today
, vol.10
, pp. 1421-1433
-
-
Whitebread, S.1
-
20
-
-
46249090791
-
Prediction of drug-target interaction networks from the integration of chemical and genomic spaces
-
Yamanishi,Y. et al. (2008) Prediction of drug-target interaction networks from the integration of chemical and genomic spaces. Bioinformatics, 24, i232-i240.
-
(2008)
Bioinformatics
, vol.24
-
-
Yamanishi, Y.1
-
21
-
-
77954230951
-
Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework
-
Yamanishi,Y. et al. (2010) Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework. Bioinformatics, 26, i246-i254.
-
(2010)
Bioinformatics
, vol.26
-
-
Yamanishi, Y.1
|