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Volumn 5, Issue 7, 2012, Pages 952-962

Resveratrol helps recovery from fatty liver and protects against hepatocellular carcinoma induced by hepatitis B virus X protein in a mouse model

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; GLUTATHIONE; HEPATITIS B VIRUS X PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; R 5010; REACTIVE OXYGEN METABOLITE; RESVERATROL; SIRTUIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG;

EID: 84866446123     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-12-0001     Document Type: Article
Times cited : (54)

References (42)
  • 1
    • 58149376548 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatocellular carcinoma
    • Aravalli RN, Steer CJ, Cressman EN. Molecular mechanisms of hepatocellular carcinoma. Hepatology 2008;48:2047-63.
    • (2008) Hepatology , vol.48 , pp. 2047-2063
    • Aravalli, R.N.1    Steer, C.J.2    Cressman, E.N.3
  • 2
    • 7044229778 scopus 로고    scopus 로고
    • Primary liver cancer: Worldwide incidence and trends
    • Bosch FX, Ribes J, Díaz M, Cléries R. Primary liver cancer: worldwide incidence and trends. Gastroenterology 2004;127 Suppl 1:S5-16.
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL. 1
    • Bosch, F.X.1    Ribes, J.2    Díaz, M.3    Cléries, R.4
  • 3
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
    • DOI 10.1053/j.gastro.2007.04.061, PII S0016508507007998
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007;132:2557-76. (Pubitemid 46890874)
    • (2007) Gastroenterology , vol.132 , Issue.7 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 4
    • 77952730428 scopus 로고    scopus 로고
    • The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis
    • Ascha MS, Hanouneh IA, Lopez R, Tamimi TA, Feldstein AF, Zein NN. The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis. Hepatology 2010;51:1972-8.
    • (2010) Hepatology , vol.51 , pp. 1972-1978
    • Ascha, M.S.1    Hanouneh, I.A.2    Lopez, R.3    Tamimi, T.A.4    Feldstein, A.F.5    Zein, N.N.6
  • 5
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection
    • Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology 2010;51:1820-32.
    • (2010) Hepatology , vol.51 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 7
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • DOI 10.1038/nrd2060, PII NRD2060
    • Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006;5:493-506. (Pubitemid 44136961)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 8
    • 80053456372 scopus 로고    scopus 로고
    • Calorie restriction and resveratrol in cardiovascular health and disease
    • Dolinsky VW, Dyck JR. Calorie restriction and resveratrol in cardiovascular health and disease. Biochim Biophys Acta 2011;1812:1477-89.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 1477-1489
    • Dolinsky, V.W.1    Dyck, J.R.2
  • 10
    • 33846796318 scopus 로고    scopus 로고
    • Resveratrol, a red wine polyphenol, attenuates ethanol-induced oxidative stress in rat liver
    • DOI 10.1016/j.lfs.2006.11.044, PII S0024320506009404
    • Kasdallah-Grissa A, Mornagui B, Aouani E, Hammami M, El May M, Gharbi N, et al. Resveratrol, a red wine polyphenol, attenuates ethanol-induced oxidative stress in rat liver. Life Sci 2007;80:1033-9. (Pubitemid 46204723)
    • (2007) Life Sciences , vol.80 , Issue.11 , pp. 1033-1039
    • Kasdallah-Grissa, A.1    Mornagui, B.2    Aouani, E.3    Hammami, M.4    El, M.M.5    Gharbi, N.6    Kamoun, A.7    El-Fazaa, S.8
  • 13
    • 74649083195 scopus 로고    scopus 로고
    • Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma
    • Bishayee A, Politis T, Darvesh AS. Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma. Cancer Treat Rev 2010;36:43-53.
    • (2010) Cancer Treat Rev , vol.36 , pp. 43-53
    • Bishayee, A.1    Politis, T.2    Darvesh, A.S.3
  • 14
    • 62549154478 scopus 로고    scopus 로고
    • Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: Inhibition of cell proliferation and induction of apoptosis
    • Bishayee A, Dhir N. Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. ChemBiol Interact 2009;179:131-44.
    • (2009) ChemBiol Interact , vol.179 , pp. 131-144
    • Bishayee, A.1    Dhir, N.2
  • 15
    • 77953229913 scopus 로고    scopus 로고
    • Resveratrol suppresses oxidative stress and inflammatory response in diethylni-trosamine-initiated rat hepatocarcinogenesis
    • Bishayee A, Barnes KF, Bhatia D, Darvesh AS, Carroll RT. Resveratrol suppresses oxidative stress and inflammatory response in diethylni-trosamine- initiated rat hepatocarcinogenesis. Cancer Prev Res 2010;3:753-63.
    • (2010) Cancer Prev Res , vol.3 , pp. 753-763
    • Bishayee, A.1    Barnes, K.F.2    Bhatia, D.3    Darvesh, A.S.4    Carroll, R.T.5
  • 16
    • 84855860394 scopus 로고    scopus 로고
    • Alteration of hepatic proinflammatory cytokines is involved in the resveratrol-mediated chemoprevention of chemically-induced hepatocarcinogenesis
    • Mbimba T, Awale P, Bhatia D, Geldenhuys WJ, Darvesh AS, Carroll RT, et al. Alteration of hepatic proinflammatory cytokines is involved in the resveratrol-mediated chemoprevention of chemically-induced hepatocarcinogenesis. Curr Pharm Biotechnol 2012;13:229-34.
    • (2012) Curr Pharm Biotechnol , vol.13 , pp. 229-234
    • Mbimba, T.1    Awale, P.2    Bhatia, D.3    Geldenhuys, W.J.4    Darvesh, A.S.5    Carroll, R.T.6
  • 17
    • 30144444237 scopus 로고    scopus 로고
    • Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice
    • Wu BK, Li CC, Chen HJ, Chang JL, Jeng KS, Chou CK, et al. Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice. Biochem Biophys Res Commun 2006;340:916-28.
    • (2006) Biochem Biophys Res Commun , vol.340 , pp. 916-928
    • Wu, B.K.1    Li, C.C.2    Chen, H.J.3    Chang, J.L.4    Jeng, K.S.5    Chou, C.K.6
  • 18
    • 40949143283 scopus 로고    scopus 로고
    • Chemopreventive effect of silymarin on liver pathology in HBV X protein transgenic mice
    • DOI 10.1158/0008-5472.CAN-07-2450
    • Wu YF, Fu SL, Kao CH, Yang CW, Lin CH, Hsu MT, et al. Chemopreventive effect of silymarin on liver pathology in HBV X protein transgenic mice. Cancer Res 2008;68:2033-42. (Pubitemid 351416591)
    • (2008) Cancer Research , vol.68 , Issue.6 , pp. 2033-2042
    • Wu, Y.-F.1    Fu, S.-L.2    Kao, C.-H.3    Yang, C.-W.4    Lin, C.-H.5    Hsu, M.-T.6    Tsai, T.-F.7
  • 20
    • 0029069933 scopus 로고
    • Visualization of the transport pathways of low density lipoproteins across the endothelial cells in the branched regions of rat arteries
    • Kao CH, Chen JK, Kuo JS, Yang VC. Visualization of the transport pathways of low density lipoproteins across the endothelial cells in the branched regions of rat arteries. Atherosclerosis 1995;116:27-41.
    • (1995) Atherosclerosis , vol.116 , pp. 27-41
    • Kao, C.H.1    Chen, J.K.2    Kuo, J.S.3    Yang, V.C.4
  • 24
    • 79959261445 scopus 로고    scopus 로고
    • What is new for an old molecule? Systematic review and recommendations on the use of resveratrol
    • Vang O, Ahmad N, Baile CA, Baur JA, Brown K, Csiszar A, et al. What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One 2011;6:e19881.
    • (2011) PLoS One , vol.6
    • Vang, O.1    Ahmad, N.2    Baile, C.A.3    Baur, J.A.4    Brown, K.5    Csiszar, A.6
  • 26
    • 34247637220 scopus 로고    scopus 로고
    • Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARγ
    • DOI 10.1053/j.gastro.2007.03.039, PII S001650850700563X
    • Kim KH, Shin HJ, Kim K, Choi HM, Rhee SH, Moon HB, et al. Hepatitis B virus X protein induces hepatic steatosis via transcriptional activation of SREBP1 and PPARgamma. Gastroenterology 2007;132:1955-67. (Pubitemid 46677949)
    • (2007) Gastroenterology , vol.132 , Issue.5 , pp. 1955-1967
    • Kim, K.H.1    Shin, H.2    Kim, K.3    Choi, H.M.4    Rhee, S.H.5    Moon, H.6    Kim, H.H.7    Yang, U.S.8    Yu, D.9    Cheong, J.10
  • 27
    • 58149291663 scopus 로고    scopus 로고
    • Hepatitis B virus X protein induces lipogenic transcription factor SREBP1 and fatty acid synthase through the activation of nuclear receptor LXRalpha
    • Kim K, Kim KH, Kim HH, Cheong J. Hepatitis B virus X protein induces lipogenic transcription factor SREBP1 and fatty acid synthase through the activation of nuclear receptor LXRalpha. Biochem J 2008;416:219-30.
    • (2008) Biochem J , vol.416 , pp. 219-230
    • Kim, K.1    Kim, K.H.2    Kim, H.H.3    Cheong, J.4
  • 28
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • DOI 10.1172/JCI200215593
    • Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 2002;109:1125-31. (Pubitemid 34496588)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.9 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 30
    • 0346003777 scopus 로고    scopus 로고
    • Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor γ1 (PPARγ1) overexpression
    • DOI 10.1074/jbc.M210062200
    • Yu S, Matsusue K, Kashireddy P, Cao WQ, Yeldandi V, Yeldandi AV, et al. Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J Biol Chem 2003;278:498-505. (Pubitemid 36043602)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.1 , pp. 498-505
    • Yu, S.1    Matsusue, K.2    Kashireddy, P.3    Cao, W.-Q.4    Yeldandi, V.5    Yeldandi, A.V.6    Rao, M.S.7    Gonzalez, F.J.8    Reddy, J.K.9
  • 31
    • 65449149413 scopus 로고    scopus 로고
    • Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-associated hepatocellular carcinoma
    • Na TY, Shin YK, Roh KJ, Kang SA, Hong I, Oh SJ, et al. Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-associated hepatocellular carcinoma. Hepatology 2009;49:1122-31.
    • (2009) Hepatology , vol.49 , pp. 1122-1131
    • Na, T.Y.1    Shin, Y.K.2    Roh, K.J.3    Kang, S.A.4    Hong, I.5    Oh, S.J.6
  • 32
    • 0035907311 scopus 로고    scopus 로고
    • The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade
    • Lee YI, Kang-Park S, Do SI, Lee YI. The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade. J Biol Chem 2001;276:16969-77.
    • (2001) J Biol Chem , vol.276 , pp. 16969-16977
    • Lee, Y.I.1    Kang-Park, S.2    Do, S.I.3    Lee, Y.I.4
  • 34
    • 68049127791 scopus 로고    scopus 로고
    • Second-hand smoke stimulates lipid accumulation in the liver by modulating AMPK and SREBP-1
    • Yuan H, Shyy JY, Martins-Green M. Second-hand smoke stimulates lipid accumulation in the liver by modulating AMPK and SREBP-1. J Hepatol 2009;51:535-47.
    • (2009) J Hepatol , vol.51 , pp. 535-547
    • Yuan, H.1    Shyy, J.Y.2    Martins-Green, M.3
  • 35
    • 77953480631 scopus 로고    scopus 로고
    • Biochemical effects of SIRT1 activators
    • Baur JA. Biochemical effects of SIRT1 activators. Biochim Biophys Acta 2010;1804:1626-34.
    • (2010) Biochim Biophys Acta , vol.1804 , pp. 1626-1634
    • Baur, J.A.1
  • 36
    • 38749083797 scopus 로고    scopus 로고
    • Effect of Resveratrol on Oxidative Stress Enzymes in Rats Subjected to 70% Partial Hepatectomy
    • DOI 10.1016/j.transproceed.2007.11.021, PII S004113450701370X
    • Kirimlioglu V, Karakayali H, Turkoglu S, Haberal M. Effect of resveratrol on oxidative stress enzymes in rats subjected to 70% partial hepatectomy. Transplant Proc 2008;40:293-6. (Pubitemid 351186622)
    • (2008) Transplantation Proceedings , vol.40 , Issue.1 , pp. 293-296
    • Kirimlioglu, V.1    Karakayali, H.2    Turkoglu, S.3    Haberal, M.4
  • 38
    • 84984548367 scopus 로고    scopus 로고
    • Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: A follow-up study in Taiwan
    • Chen CL, Yang HI, Yang WS, Liu CJ, Chen PJ, You SL, et al. Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan. Gastroenterology 2008;135:111-21.
    • (2008) Gastroenterology , vol.135 , pp. 111-121
    • Chen, C.L.1    Yang, H.I.2    Yang, W.S.3    Liu, C.J.4    Chen, P.J.5    You, S.L.6
  • 39
    • 0036170178 scopus 로고    scopus 로고
    • The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmful
    • Juan ME, Vinardell MP, Planas JM. The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmful. J Nutr 2002;132:257-60. (Pubitemid 34135604)
    • (2002) Journal of Nutrition , vol.132 , Issue.2 , pp. 257-260
    • Emlia, J.M.1    Pilar, V.M.2    Planas, J.M.3
  • 41
    • 68049147267 scopus 로고    scopus 로고
    • Safety studies conducted on high-purity trans-resveratrol in experimental animals
    • Williams LD, Burdock GA, Edwards JA, Beck M, Bausch J. Safety studies conducted on high-purity trans-resveratrol in experimental animals. Food Chem Toxicol 2009;47:2170-82.
    • (2009) Food Chem Toxicol , vol.47 , pp. 2170-2182
    • Williams, L.D.1    Burdock, G.A.2    Edwards, J.A.3    Beck, M.4    Bausch, J.5


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