Convergent asymmetric synthesis of (+)-aureothin employing an oxygenase-mediated resolution step

Angewandte Chemie - International Edition

Volumn 51, Issue 38, 2012, Pages 9587-9591

  Henrot, Matthias ^a   Richter, Martin E A ^b   Maddaluno, Jacques ^a   Hertweck, Christian ^b   De Paolis, Michaël ^a  

^a UNIVERSITÉ ET INSA DE ROUEN   (France)

^b HANS KNÖLL INSTITUTE   (Germany)

Author keywords

aureothin; cytochrome P450; natural products; oxidation; parallel kinetic resolution

Indexed keywords

ASYMMETRIC SYNTHESIS; AUREOTHIN; CARBON SKELETON; CYTOCHROME P450; DESYM-METRIZATION; ENANTIOPURE; MONOOXYGENASES; NATURAL PRODUCTS; PARALLEL KINETIC RESOLUTION; TARGET MOLECULE;

CATALYSIS; OXIDATION;

CHEMISTRY;

AUREOTHAN; CHROMONE DERIVATIVE; CYTOCHROME P450; OXYGENASE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; KINETICS; METABOLISM; STEREOISOMERISM;

CHROMONES; CYTOCHROME P-450 ENZYME SYSTEM; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OXYGENASES; STEREOISOMERISM;

EID: 84866426333     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201204259     Document Type: Article

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