Kinetic and mechanistic differences in the interactions between caldendrin and calmodulin with AKAP79 suggest different roles in synaptic function

Journal of Molecular Recognition

Volumn 25, Issue 10, 2012, Pages 495-503

  Seeger, Christian ^a,b   Gorny, Xenia ^c   Reddy, Pasham Parameshwar ^c   Seidenbecher, Constanze ^c   Danielson, U Helena ^a,b  

^a Beactica   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

Author keywords

A kinase anchoring protein; caldendrin; calmodulin; induced fit; postsynaptic density; surface plasmon resonance

Indexed keywords

AKAP5 PROTEIN, HUMAN; CA2+ BINDING PROTEIN 1; CA2+-BINDING PROTEIN-1; CALCIUM; CALCIUM BINDING PROTEIN; CALMODULIN; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; HYBRID PROTEIN;

ARTICLE; BINDING COMPETITION; BINDING SITE; BRAIN LEVEL; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; KINETICS; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SOLUTION AND SOLUBILITY; SURFACE PLASMON RESONANCE; SYNAPSE;

A KINASE ANCHOR PROTEINS; BINDING SITES; BINDING, COMPETITIVE; BRAIN CHEMISTRY; CALCIUM; CALCIUM-BINDING PROTEINS; CALMODULIN; HUMANS; KINETICS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SOLUTIONS; SURFACE PLASMON RESONANCE; SYNAPSES;

EID: 84866426155     PISSN: 09523499     EISSN: 10991352     Source Type: Journal    
DOI: 10.1002/jmr.2215     Document Type: Article

References (28)

1. Berggard T, Linse S, James P,. 2007. Methods for the detection and analysis of protein-protein interactions. Proteomics 7: 2833-2842. (Pubitemid 47359924)
2. Berridge MJ, Lipp P, Bootman MD,. 2000. The versatility and universality of calcium signalling. Nat. Rev. Mol. Cell Biol. 1: 11-21.
3. Bhattacharyya S, Biou V, Xu W, Schlüter O, Malenka RC,. 2009. A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors. Nat. Neurosci. 12: 172-181.
4. Chin D, Means AR,. 2000. Calmodulin: a prototypical calcium sensor. Trends Cell Biol. 10: 322-328. (Pubitemid 30445239)
5. Collins MO, Husi H, Yu L, Brandon JM, Anderson CNG, Blackstock WP, Choudhary JS, Grant SGN,. 2006. Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome. J. Neurochem. 97: 16-23.
6. Dell'Acqua ML, Smith KE, Gorski JA, Horne EA, Gibson ES, Gomez LL,. 2006. Regulation of neuronal PKA signaling through AKAP targeting dynamics. Eur. J. Cell Biol. 85: 627-633. (Pubitemid 43863036)
7. Dwane S, Kiely PA,. 2011. Tools used to study how protein complexes are assembled in signaling cascades. Bioeng. Bugs 2: 247-259.
8. Edwards PR, Maule CH, Leatherbarrow RJ, Winzor DJ,. 1998. Second-order kinetic analysis of IAsys biosensor data: its use and applicability. Anal. Biochem. 263: 1-12. (Pubitemid 28445417)
9. 2+/calmodulin. J. Biol. Chem. 272: 17038-17044. (Pubitemid 27289810)
10. Findeisen F, Minor DL,. 2010. Structural basis for the differential effects of CaBP1 and calmodulin on Ca(V)1.2 calcium-dependent inactivation. Structure 18: 1617-1631.
11. 2+-myristoyl switch of recoverin. J. Neurochem. 113: 1150-1162.
12. 2+/calmodulin is enhanced by PDZ-binding proteins. J. Biochem. 138: 177-182. (Pubitemid 41265368)
13. Geitmann M, Dahl G, Danielson UH,. 2011. Mechanistic and kinetic characterization of hepatitis C virus NS3 protein interactions with NS4A and protease inhibitors. J. Mol. Recognit. 24: 60-70.
14. Geitmann M, Danielson UH,. 2004. Studies of substrate-induced conformational changes in human cytomegalovirus protease using optical biosensor technology. Anal. Biochem. 332: 203-214. (Pubitemid 39485728)
15. Glück JM, Koenig BW, Willbold D,. 2011. Nanodiscs allow the use of integral membrane proteins as analytes in surface plasmon resonance studies. Anal. Biochem. 408: 46-52.
16. Gorny X, Mikhaylova M, Seeger C, Reddy PP, Reissner C, Schott BH, Danielson UH, Kreutz MR, Seidenbecher C,. 2012. AKAP79/150 interacts with the neuronal calcium-binding protein caldendrin. J. Neurochem. 1: 714-726.
17. Karlsson R., 1999. Affinity analysis of non-steady-state data obtained under mass transport limited conditions using BIAcore technology. J. Mol. Recognit. 12: 285-292. (Pubitemid 129708591)
18. Karlsson R, Katsamba PS, Nordin H, Pol E, Myszka DG,. 2006. Analyzing a kinetic titration series using affinity biosensors. Anal. Biochem. 349: 136-147. (Pubitemid 43129567)
19. Klemmer P, Smit A, Li K,. 2009. Proteomics analysis of immuno-precipitated synaptic protein complexes. J. Proteomics 72: 82-90.
20. Larsson M, Hjalm G, Sakwe AM, Engstrom A, Hoglund AS, Larsson E, Robinson RC, Sundberg C, Rask L,. 2003. Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins. Biochem. J. 373: 381-391. (Pubitemid 36897841)
21. 2+-binding protein caldendrin: gene structure, splice isoforms, and expression in the rat central nervous system. Mol. Cell Neurocsci. 19: 459-475. (Pubitemid 34293466)
22. Le AV, Tavalin SJ, Dodge-Kafka KL,. 2011. Identification of AKAP79 as a protein phosphatase 1 catalytic binding protein. Biochemistry 50: 5279-5291.
23. Popov N, Schmitt M, Schulzeck S, Matthies H,. 1975. Reliable micromethod for determination of the protein content in tissue homogenates. Acta Biol. Med. Ger. 34: 1441-1446.
24. Rich RL, Myszka DG,. 2010. Grading the commercial optical biosensor literature class of 2008: the mighty binders. J. Mol. Recognit. 23: 1-64.
25. Rich RL, Myszka DG,. 2011. Survey of the 2009 commercial optical biosensor literature. J. Mol. Recognit. 24: 892-914.
26. Sanderson JL, Dell'Acqua ML,. 2011. AKAP signaling complexes in regulation of excitatory synaptic plasticity. Neuroscientist 17: 321-336.
27. Seidenbecher CI, Langnaese K, Sanmart-Vila L, Boeckers TM, Smalla KH, Sabel BA, Garner CC, Gundelfinger ED, Kreutz MR,. 1998. Caldendrin, a novel neuronal calcium-binding protein confined to the somato-dendritic compartment. J. Biol. Chem. 273: 21324-21331. (Pubitemid 28385426)
28. Wang X, Hu B, Zieba A, Neumann NG, Kasper-Sonnenberg M, Honsbein A, Hultqvist G, Conze T, Witt W, Limbach C, Geitmann M, Danielson H, Kolarow R, Niemann G, Lessmann V, Kilimann MW,. 2009. A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1. J. Neurosci. 29: 12584-12596.