Design, synthesis, and in vitro antimicrobial activities of novel azetidinyl-3-quinazolin-4-one hybrids

Medicinal Chemistry Research

Volumn 21, Issue 10, 2012, Pages 2762-2771

  Myangar, Kruti Navin ^a   Raval, Jignesh Priyakant ^a  

^a Ashok & Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences   (India)

Author keywords

Antibacterial; Antifungal and antitubercular activity; Azetidinone; Isonicotinic acid hydrazide; Quinazoline 4 one; Schiff base

Indexed keywords

2 [(2 CHLOROBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL)QUINAZOLINE 4 ONE; 2 [(2 HYDROXYBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL)QUINAZOLINE 4 ONE; 2 [(2 NITROBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL) QUINAZOLINE 4 ONE; 2 [(3 NITROBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL) QUINAZOLINE 4 ONE; 2 [(4 BROMOBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL)QUINAZOLINE 4 ONE; 2 [(4 CHLOROBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL)QUINAZOLINE 4 ONE; 2 [(4 ETHYLBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL)QUINAZOLINE 4 ONE; 2 [(4 HYDROXYBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL)QUINAZOLINE 4 ONE; 2 [(4 METHOXYBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL]QUINAZOLINE 4 ONE; 2 [(4 NITROBENZYLIDENE) HYDRAZINOMETHYL] 3 (N ISONICOTINAMIDE YL)QUINAZOLINE 4 ONE; 2 [(4' OXO 3' CHLORO 2' (2 HYDROXYPHENYL) AZETIDIN 1' YLAMINO] METHYL] 3 (N ISONICOTINAMIDE YL) QUINAZOLIN 4 ONE; 2 [(4' OXO 3' CHLORO 2' (2 NITROPHENYL) AZETIDIN 1' YLAMINO] METHYL] 3 (N ISONICOTINAMIDE YL) QUINAZOLIN 4 ONE; 2 [(4' OXO 3' CHLORO 2' (3 NITROPHENYL) AZETIDIN 1' YLAMINO] METHYL] 3 (N ISONICOTINAMIDE YL) QUINAZOLIN 4 ONE; 2 [(4' OXO 3' CHLORO 2' (4 BROMOPHENYL) AZETIDIN 1' YLAMINO] METHYL] 3 (N ISONICOTINAMIDE YL)QUINAZOLIN 4 ONE; 2 [(4' OXO 3' CHLORO 2' (4 METHOXYPHENYL) AZETIDIN 1' YLAMINO] METHYL] 3 (N ISONICOTINAMIDE YL)QUINAZOLIN 4 ONE; 2 [(4' OXO 3' CHLORO 2' (4 NITROPHENYL) AZETIDIN 1' YLAMINO] METHYL] 3 (N ISONICOTINAMIDE YL) QUINAZOLIN 4 ONE; 2 [(4' OXO 3' CHLORO 2' PHENYLAZETIDIN 1' YLAMINO) METHYL] 3 (N ISONICOTINAMIDE YL) QUINAZOLIN 4 ONE; 2 BENZYLIDENEHYDRAZINOMETHYL 3 (N ISONICOTINAMIDE YL] QUINAZOLINE 4 ONE; 2 HYDRAZINOMETHYL 3 (N ISONICOTINAMIDE YL) QUINAZOLINE 4 ONE; AMPICILLIN; CHLORAMPHENICOL; CIPROFLOXACIN; GENTAMICIN; GRISEOFULVIN; ISONIAZID; NORFLOXACIN; NYSTATIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTITUBERCULAR ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACILLUS SUBTILIS; CANDIDA ALBICANS; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; FUNGAL STRAIN; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; INFRARED SPECTROSCOPY; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHI; STAPHYLOCOCCUS AUREUS;

EID: 84866417452     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9808-9     Document Type: Article

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