메뉴 건너뛰기




Volumn 12, Issue 8, 2012, Pages 874-879

Regulation of cell death and survival by resveratrol: Implications for cancer therapy

Author keywords

Apoptosis; Cancer; Cancer therapy; Resveratrol; Signaling

Indexed keywords

BATABULIN; CASPASE 3; CASPASE 7; CASPASE 9; CYCLOOXYGENASE 2; CYTOCHROME C; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; DEATH RECEPTOR; FAS ANTIGEN; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; INTERLEUKIN 1BETA; MITOCHONDRIAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN MCL 1; PROTEIN P21; PROTEIN S6; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RESVERATROL; SILENT INFORMATION REGULATOR PROTEIN 2; SIRTUIN 1; STAT3 PROTEIN; SURVIVIN;

EID: 84866416684     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/187152012802650129     Document Type: Article
Times cited : (11)

References (82)
  • 1
    • 38349194472 scopus 로고    scopus 로고
    • Cell death in health and disease
    • Lockshin, R.A.; Zakeri, Z. Cell death in health and disease. J. Cell Mol. Med., 2007, 11(6), 1214-1224.
    • (2007) J. Cell Mol. Med , vol.11 , Issue.6 , pp. 1214-1224
    • Lockshin, R.A.1    Zakeri, Z.2
  • 2
    • 33746886979 scopus 로고    scopus 로고
    • Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
    • Fulda, S.; Debatin, K.M. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene, 2006, 25(34), 4798-4811.
    • (2006) Oncogene , vol.25 , Issue.34 , pp. 4798-4811
    • Fulda, S.1    Debatin, K.M.2
  • 3
    • 49349117553 scopus 로고    scopus 로고
    • Apoptosis signaling pathways in anticancer therapy
    • Fulda, S.; Debatin, K.M. Apoptosis signaling pathways in anticancer therapy. Curr. Cancer Ther. Rev., 2008, 4, 14-20.
    • (2008) Curr. Cancer Ther. Rev , vol.4 , pp. 14-20
    • Fulda, S.1    Debatin, K.M.2
  • 4
    • 58149296552 scopus 로고    scopus 로고
    • Tumor resistance to apoptosis
    • Fulda, S. Tumor resistance to apoptosis. Int. J. Cancer, 2009, 124(3), 511-515.
    • (2009) Int. J. Cancer , vol.124 , Issue.3 , pp. 511-515
    • Fulda, S.1
  • 5
    • 9244224723 scopus 로고    scopus 로고
    • Intrinsic tumour suppression
    • Lowe, S.W.; Cepero, E.; Evan, G. Intrinsic tumour suppression. Nature, 2004, 432(7015), 307-315.
    • (2004) Nature , vol.432 , Issue.7015 , pp. 307-315
    • Lowe, S.W.1    Cepero, E.2    Evan, G.3
  • 7
    • 39749182234 scopus 로고    scopus 로고
    • Apoptosis: Controlled demolition at the cellular level
    • Taylor, R.C.; Cullen, S.P.; Martin, S.J. Apoptosis: controlled demolition at the cellular level. Nat. Rev. Mol. Cell Biol., 2008, 9(3), 231-241.
    • (2008) Nat. Rev. Mol. Cell Biol , vol.9 , Issue.3 , pp. 231-241
    • Taylor, R.C.1    Cullen, S.P.2    Martin, S.J.3
  • 8
    • 0347601880 scopus 로고    scopus 로고
    • A decade of caspases
    • Degterev, A.; Boyce, M.; Yuan, J. A decade of caspases. Oncogene, 2003, 22(53), 8543-8567.
    • (2003) Oncogene , vol.22 , Issue.53 , pp. 8543-8567
    • Degterev, A.1    Boyce, M.2    Yuan, J.3
  • 9
    • 44749085513 scopus 로고    scopus 로고
    • Targeting the extrinsic apoptosis pathway in cancer
    • Ashkenazi, A. Targeting the extrinsic apoptosis pathway in cancer. Cytokine Growth Factor Rev., 2008, 19(3-4), 325-331.
    • (2008) Cytokine Growth Factor Rev , vol.19 , Issue.3-4 , pp. 325-331
    • Ashkenazi, A.1
  • 10
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • Adams, J.M.; Cory, S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene, 2007, 26(9), 1324-1337.
    • (2007) Oncogene , vol.26 , Issue.9 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 11
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • Kroemer, G.; Galluzzi, L.; Brenner, C. Mitochondrial membrane permeabilization in cell death. Physiol. Rev., 2007, 87(1), 99-163.
    • (2007) Physiol. Rev , vol.87 , Issue.1 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 13
    • 3543092021 scopus 로고    scopus 로고
    • Pathways of apoptotic and non-apoptotic death in tumour cells
    • Okada, H.; Mak, T.W. Pathways of apoptotic and non-apoptotic death in tumour cells. Nat. Rev. Cancer, 2004, 4(8), 592-603.
    • (2004) Nat. Rev. Cancer , vol.4 , Issue.8 , pp. 592-603
    • Okada, H.1    Mak, T.W.2
  • 14
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri, M.C.; Zalckvar, E.; Kimchi, A.; Kroemer, G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat. Rev. Mol. Cell Biol., 2007, 8(9), 741-752.
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 15
    • 62949128915 scopus 로고    scopus 로고
    • Lysosomal involvement in cell death and cancer
    • Kirkegaard, T.; Jaattela, M. Lysosomal involvement in cell death and cancer. Biochim. Biophys. Acta, 2009, 1793(4), 746-754.
    • (2009) Biochim. Biophys. Acta , vol.1793 , Issue.4 , pp. 746-754
    • Kirkegaard, T.1    Jaattela, M.2
  • 16
    • 33749178260 scopus 로고    scopus 로고
    • Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
    • Festjens, N.; Van den Berghe, T.; Vandenabeele, P. Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. Biochim. Biophys. Acta, 2006, 1757(9-10), 1371-1387.
    • (2006) Biochim. Biophys. Acta , vol.1757 , Issue.9-10 , pp. 1371-1387
    • Festjens, N.1    van den Berghe, T.2    Vandenabeele, P.3
  • 17
    • 25444440875 scopus 로고    scopus 로고
    • The role of autophagy in cancer development and response to therapy
    • Kondo, Y.; Kanzawa, T.; Sawaya, R.; Kondo, S. The role of autophagy in cancer development and response to therapy. Nat. Rev. Cancer, 2005, 5(9), 726-734.
    • (2005) Nat. Rev. Cancer , vol.5 , Issue.9 , pp. 726-734
    • Kondo, Y.1    Kanzawa, T.2    Sawaya, R.3    Kondo, S.4
  • 18
    • 0242695672 scopus 로고    scopus 로고
    • Resveratrol: From grapevines to mammalian biology
    • Pervaiz, S. Resveratrol: from grapevines to mammalian biology. FASEB J., 2003, 17(14), 1975-1985.
    • (2003) FASEB J , vol.17 , Issue.14 , pp. 1975-1985
    • Pervaiz, S.1
  • 19
    • 0034909129 scopus 로고    scopus 로고
    • A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol
    • Gusman, J.; Malonne, H.; Atassi, G. A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol. Carcinogenesis, 2001, 22(8), 1111-1117.
    • (2001) Carcinogenesis , vol.22 , Issue.8 , pp. 1111-1117
    • Gusman, J.1    Malonne, H.2    Atassi, G.3
  • 20
    • 73449100838 scopus 로고    scopus 로고
    • Resveratrol: Its biologic targets and functional activity
    • Pervaiz, S.; Holme, A.L. Resveratrol: its biologic targets and functional activity. Antioxid Redox Signal, 2009, 11(11), 2851-2897.
    • (2009) Antioxid Redox Signal , vol.11 , Issue.11 , pp. 2851-2897
    • Pervaiz, S.1    Holme, A.L.2
  • 24
    • 70349104624 scopus 로고    scopus 로고
    • Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions
    • Reis-Sobreiro, M.; Gajate, C.; Mollinedo, F. Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions. Oncogene, 2009, 28(36), 3221-3234.
    • (2009) Oncogene , vol.28 , Issue.36 , pp. 3221-3234
    • Reis-Sobreiro, M.1    Gajate, C.2    Mollinedo, F.3
  • 25
    • 10644246821 scopus 로고    scopus 로고
    • Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
    • Delmas, D.; Rebe, C.; Micheau, O.; Athias, A.; Gambert, P.; Grazide, S.; Laurent, G.; Latruffe, N.; Solary, E. Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells. Oncogene, 2004, 23(55), 8979-8986.
    • (2004) Oncogene , vol.23 , Issue.55 , pp. 8979-8986
    • Delmas, D.1    Rebe, C.2    Micheau, O.3    Athias, A.4    Gambert, P.5    Grazide, S.6    Laurent, G.7    Latruffe, N.8    Solary, E.9
  • 26
    • 16744364517 scopus 로고    scopus 로고
    • Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells
    • Delmas, D.; Rebe, C.; Lacour, S.; Filomenko, R.; Athias, A.; Gambert, P.; Cherkaoui-Malki, M.; Jannin, B.; Dubrez-Daloz, L.; Latruffe, N.; Solary, E. Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells. J. Biol. Chem., 2003, 278(42), 41482-41490.
    • (2003) J. Biol. Chem , vol.278 , Issue.42 , pp. 41482-41490
    • Delmas, D.1    Rebe, C.2    Lacour, S.3    Filomenko, R.4    Athias, A.5    Gambert, P.6    Cherkaoui-Malki, M.7    Jannin, B.8    Dubrez-Daloz, L.9    Latruffe, N.10    Solary, E.11
  • 28
    • 70349859902 scopus 로고    scopus 로고
    • Fighting cancer with red wine? Molecular mechanisms of resveratrol
    • Kraft, T.E.; Parisotto, D.; Schempp, C.; Efferth, T. Fighting cancer with red wine? Molecular mechanisms of resveratrol. Crit. Rev. Food Sci. Nutr., 2009, 49(9), 782-799.
    • (2009) Crit. Rev. Food Sci. Nutr , vol.49 , Issue.9 , pp. 782-799
    • Kraft, T.E.1    Parisotto, D.2    Schempp, C.3    Efferth, T.4
  • 29
    • 1642576201 scopus 로고    scopus 로고
    • Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol
    • Fulda, S.; Debatin, K.M. Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol. Cancer Res., 2004, 64(1), 337-346.
    • (2004) Cancer Res , vol.64 , Issue.1 , pp. 337-346
    • Fulda, S.1    Debatin, K.M.2
  • 30
    • 41449093973 scopus 로고    scopus 로고
    • Differential effect of proIGF-II and IGF-II on resveratrol induced cell death by regulating survivin cellular localization and mitochondrial depolarization in breast cancer cells
    • Singh, S.K.; Moretta, D.; Almaguel, F.; Wall, N.R.; De Leon, M.; De Leon, D. Differential effect of proIGF-II and IGF-II on resveratrol induced cell death by regulating survivin cellular localization and mitochondrial depolarization in breast cancer cells. Growth Factors, 2007, 25(6), 363-372.
    • (2007) Growth Factors , vol.25 , Issue.6 , pp. 363-372
    • Singh, S.K.1    Moretta, D.2    Almaguel, F.3    Wall, N.R.4    de Leon, M.5    de Leon, D.6
  • 31
    • 0038777473 scopus 로고    scopus 로고
    • Resveratrol induces downregulation in survivin expression and apoptosis in HTLV-1-infected cell lines: A prospective agent for adult T cell leukemia chemotherapy
    • Hayashibara, T.; Yamada, Y.; Nakayama, S.; Harasawa, H.; Tsuruda, K.; Sugahara, K.; Miyanishi, T.; Kamihira, S.; Tomonaga, M.; Maita, T. Resveratrol induces downregulation in survivin expression and apoptosis in HTLV-1-infected cell lines: a prospective agent for adult T cell leukemia chemotherapy. Nutr Cancer, 2002, 44(2), 193-201.
    • (2002) Nutr Cancer , vol.44 , Issue.2 , pp. 193-201
    • Hayashibara, T.1    Yamada, Y.2    Nakayama, S.3    Harasawa, H.4    Tsuruda, K.5    Sugahara, K.6    Miyanishi, T.7    Kamihira, S.8    Tomonaga, M.9    Maita, T.10
  • 32
    • 33947197883 scopus 로고    scopus 로고
    • Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells
    • Bhardwaj, A.; Sethi, G.; Vadhan-Raj, S.; Bueso-Ramos, C.; Takada, Y.; Gaur, U.; Nair, A.S.; Shishodia, S.; Aggarwal, B.B. Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood, 2007, 109(6), 2293-2302.
    • (2007) Blood , vol.109 , Issue.6 , pp. 2293-2302
    • Bhardwaj, A.1    Sethi, G.2    Vadhan-Raj, S.3    Bueso-Ramos, C.4    Takada, Y.5    Gaur, U.6    Nair, A.S.7    Shishodia, S.8    Aggarwal, B.B.9
  • 33
    • 36448992018 scopus 로고    scopus 로고
    • Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4', 5 tri-hydroxystilbene): Molecular mechanisms and therapeutic potential
    • Shankar, S.; Chen, Q.; Siddiqui, I.; Sarva, K.; Srivastava, R.K. Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4', 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential. J Mol Signal, 2007, 2, 7.
    • (2007) J Mol Signal , vol.2 , pp. 7
    • Shankar, S.1    Chen, Q.2    Siddiqui, I.3    Sarva, K.4    Srivastava, R.K.5
  • 34
    • 14844312113 scopus 로고    scopus 로고
    • Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling
    • Fulda, S.; Debatin, K.-M. Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling. Eur. J. Cancer, 2005, 41(5), 786-798.
    • (2005) Eur. J. Cancer , vol.41 , Issue.5 , pp. 786-798
    • Fulda, S.1    Debatin, K.-M.2
  • 36
    • 76049106562 scopus 로고    scopus 로고
    • Resveratrol down-regulates survivin and induces apoptosis in human multidrug-resistant SPCA-1/CDDP cells
    • Zhao, W.; Bao, P.; Qi, H.; You, H. Resveratrol down-regulates survivin and induces apoptosis in human multidrug-resistant SPCA-1/CDDP cells. Oncol. Rep., 2010, 23(1), 279-286.
    • (2010) Oncol. Rep , vol.23 , Issue.1 , pp. 279-286
    • Zhao, W.1    Bao, P.2    Qi, H.3    You, H.4
  • 37
    • 77449085174 scopus 로고    scopus 로고
    • Enhancing effectiveness of the MDR-sensitive compound T138067 using advanced treatment with negative modulators of the drug-resistant protein survivin
    • Ling, X.; He, X.; Apontes, P.; Cao, F.; Azrak, R.G.; Li, F. Enhancing effectiveness of the MDR-sensitive compound T138067 using advanced treatment with negative modulators of the drug-resistant protein survivin. Am J Transl Res, 2009, 1(4), 393-405.
    • (2009) Am J Transl Res , vol.1 , Issue.4 , pp. 393-405
    • Ling, X.1    He, X.2    Apontes, P.3    Cao, F.4    Azrak, R.G.5    Li, F.6
  • 39
    • 45849113190 scopus 로고    scopus 로고
    • Inhibition of STAT3 expression and signaling in resveratrol-differentiated medulloblastoma cells
    • Yu, L.J.; Wu, M.L.; Li, H.; Chen, X.Y.; Wang, Q.; Sun, Y.; Kong, Q.Y.; Liu, J. Inhibition of STAT3 expression and signaling in resveratrol-differentiated medulloblastoma cells. Neoplasia, 2008, 10(7), 736-744.
    • (2008) Neoplasia , vol.10 , Issue.7 , pp. 736-744
    • Yu, L.J.1    Wu, M.L.2    Li, H.3    Chen, X.Y.4    Wang, Q.5    Sun, Y.6    Kong, Q.Y.7    Liu, J.8
  • 40
    • 14744268831 scopus 로고    scopus 로고
    • Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin
    • Aziz, M.H.; Afaq, F.; Ahmad, N. Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin. Photochem Photobiol, 2005, 81(1), 25-31.
    • (2005) Photochem Photobiol , vol.81 , Issue.1 , pp. 25-31
    • Aziz, M.H.1    Afaq, F.2    Ahmad, N.3
  • 41
    • 57749170979 scopus 로고    scopus 로고
    • Chemopreventive potential of resveratrol in mouse skin tumors through regulation of mitochondrial and PI3K/AKT signaling pathways
    • Roy, P.; Kalra, N.; Prasad, S.; George, J.; Shukla, Y. Chemopreventive potential of resveratrol in mouse skin tumors through regulation of mitochondrial and PI3K/AKT signaling pathways. Pharm Res, 2009, 26(1), 211-217.
    • (2009) Pharm Res , vol.26 , Issue.1 , pp. 211-217
    • Roy, P.1    Kalra, N.2    Prasad, S.3    George, J.4    Shukla, Y.5
  • 42
    • 4444274529 scopus 로고    scopus 로고
    • Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis
    • Jazirehi, A.R.; Bonavida, B. Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis. Mol. Cancer Ther., 2004, 3(1), 71-84.
    • (2004) Mol. Cancer Ther , vol.3 , Issue.1 , pp. 71-84
    • Jazirehi, A.R.1    Bonavida, B.2
  • 43
    • 33645464650 scopus 로고    scopus 로고
    • Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein
    • Kotha, A.; Sekharam, M.; Cilenti, L.; Siddiquee, K.; Khaled, A.; Zervos, A.S.; Carter, B.; Turkson, J.; Jove, R. Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein. Mol. Cancer Ther., 2006, 5(3), 621-629.
    • (2006) Mol. Cancer Ther , vol.5 , Issue.3 , pp. 621-629
    • Kotha, A.1    Sekharam, M.2    Cilenti, L.3    Siddiquee, K.4    Khaled, A.5    Zervos, A.S.6    Carter, B.7    Turkson, J.8    Jove, R.9
  • 44
    • 35348865444 scopus 로고    scopus 로고
    • Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols
    • Gledhill, J.R.; Montgomery, M.G.; Leslie, A.G.; Walker, J.E. Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols. Proc Natl Acad Sci U S A, 2007, 104(34), 13632-13637.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.34 , pp. 13632-13637
    • Gledhill, J.R.1    Montgomery, M.G.2    Leslie, A.G.3    Walker, J.E.4
  • 46
    • 62749159928 scopus 로고    scopus 로고
    • A novel resveratrol derivative, HS1793, overcomes the resistance conferred by Bcl-2 in human leukemic U937 cells
    • Jeong, S.H.; Jo, W.S.; Song, S.; Suh, H.; Seol, S.Y.; Leem, S.H.; Kwon, T.K.; Yoo, Y.H. A novel resveratrol derivative, HS1793, overcomes the resistance conferred by Bcl-2 in human leukemic U937 cells. Biochem. Pharmacol., 2009, 77(8), 1337-1347.
    • (2009) Biochem. Pharmacol , vol.77 , Issue.8 , pp. 1337-1347
    • Jeong, S.H.1    Jo, W.S.2    Song, S.3    Suh, H.4    Seol, S.Y.5    Leem, S.H.6    Kwon, T.K.7    Yoo, Y.H.8
  • 47
    • 58149488988 scopus 로고    scopus 로고
    • The 14-3-3 proteins: Integrators of diverse signaling cues that impact cell fate and cancer development
    • Morrison, D.K. The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development. Trends Cell Biol., 2009, 19(1), 16-23.
    • (2009) Trends Cell Biol , vol.19 , Issue.1 , pp. 16-23
    • Morrison, D.K.1
  • 48
    • 0345566753 scopus 로고    scopus 로고
    • Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells
    • Clement, M.V.; Hirpara, J.L.; Chawdhury, S.H.; Pervaiz, S. Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells. Blood, 1998, 92(3), 996-1002.
    • (1998) Blood , vol.92 , Issue.3 , pp. 996-1002
    • Clement, M.V.1    Hirpara, J.L.2    Chawdhury, S.H.3    Pervaiz, S.4
  • 49
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin, M.; Cao, Y.; Greten, F.R.; Li, Z.W. NF-kappaB in cancer: from innocent bystander to major culprit. Nat. Rev. Cancer, 2002, 2(4), 301-310.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.4 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 50
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden, M.S.; Ghosh, S. Shared principles in NF-kappaB signaling. Cell, 2008, 132(3), 344-362.
    • (2008) Cell , vol.132 , Issue.3 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 51
    • 0034234254 scopus 로고    scopus 로고
    • Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase
    • Holmes-McNary, M.; Baldwin, A.S., Jr. Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase. Cancer Res., 2000, 60(13), 3477-3483.
    • (2000) Cancer Res , vol.60 , Issue.13 , pp. 3477-3483
    • Holmes-McNary, M.1    Baldwin Jr., A.S.2
  • 52
    • 0034660659 scopus 로고    scopus 로고
    • Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: Potential role of reactive oxygen intermediates and lipid peroxidation
    • Manna, S.K.; Mukhopadhyay, A.; Aggarwal, B.B. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. J. Immunol., 2000, 164(12), 6509-6519.
    • (2000) J. Immunol , vol.164 , Issue.12 , pp. 6509-6519
    • Manna, S.K.1    Mukhopadhyay, A.2    Aggarwal, B.B.3
  • 53
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung, F.; Hoberg, J.E.; Ramsey, C.S.; Keller, M.D.; Jones, D.R.; Frye, R.A.; Mayo, M.W. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. Embo J., 2004, 23(12), 2369-2380.
    • (2004) Embo J , vol.23 , Issue.12 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 55
    • 3943054839 scopus 로고    scopus 로고
    • The Sir2 family of protein deacetylases
    • Blander, G.; Guarente, L. The Sir2 family of protein deacetylases. Annu. Rev. Biochem., 2004, 73, 417-435.
    • (2004) Annu. Rev. Biochem , vol.73 , pp. 417-435
    • Blander, G.1    Guarente, L.2
  • 56
    • 79251543646 scopus 로고    scopus 로고
    • Resveratrol inhibits VEGF expression of human hepatocellular carcinoma cells through a NF-kappa B-mediated mechanism
    • Yu, H.B.; Zhang, H.F.; Zhang, X.; Li, D.Y.; Xue, H.Z.; Pan, C.E.; Zhao, S.H. Resveratrol inhibits VEGF expression of human hepatocellular carcinoma cells through a NF-kappa B-mediated mechanism. Hepatogastroenterology, 2011, 57(102-103), 1241-1246.
    • (2011) Hepatogastroenterology , vol.57 , pp. 1241-1246
    • Yu, H.B.1    Zhang, H.F.2    Zhang, X.3    Li, D.Y.4    Xue, H.Z.5    Pan, C.E.6    Zhao, S.H.7
  • 57
    • 0036733776 scopus 로고    scopus 로고
    • Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: Role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9
    • Banerjee, S.; Bueso-Ramos, C.; Aggarwal, B.B. Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9. Cancer Res., 2002, 62(17), 4945-4954.
    • (2002) Cancer Res , vol.62 , Issue.17 , pp. 4945-4954
    • Banerjee, S.1    Bueso-Ramos, C.2    Aggarwal, B.B.3
  • 58
    • 77953231047 scopus 로고    scopus 로고
    • Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis
    • Bishayee, A.; Waghray, A.; Barnes, K.F.; Mbimba, T.; Bhatia, D.; Chatterjee, M.; Darvesh, A.S. Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis. Pharm Res, 2010, 27(6), 1080-1091.
    • (2010) Pharm Res , vol.27 , Issue.6 , pp. 1080-1091
    • Bishayee, A.1    Waghray, A.2    Barnes, K.F.3    Mbimba, T.4    Bhatia, D.5    Chatterjee, M.6    Darvesh, A.S.7
  • 60
    • 0042744823 scopus 로고    scopus 로고
    • Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells
    • Estrov, Z.; Shishodia, S.; Faderl, S.; Harris, D.; Van, Q.; Kantarjian, H.M.; Talpaz, M.; Aggarwal, B.B. Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells. Blood, 2003, 102(3), 987-995.
    • (2003) Blood , vol.102 , Issue.3 , pp. 987-995
    • Estrov, Z.1    Shishodia, S.2    Faderl, S.3    Harris, D.4    van, Q.5    Kantarjian, H.M.6    Talpaz, M.7    Aggarwal, B.B.8
  • 61
    • 0026330925 scopus 로고
    • Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells
    • Rambaldi, A.; Torcia, M.; Bettoni, S.; Vannier, E.; Barbui, T.; Shaw, A.R.; Dinarello, C.A.; Cozzolino, F. Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells. Blood, 1991, 78(12), 3248-3253.
    • (1991) Blood , vol.78 , Issue.12 , pp. 3248-3253
    • Rambaldi, A.1    Torcia, M.2    Bettoni, S.3    Vannier, E.4    Barbui, T.5    Shaw, A.R.6    Dinarello, C.A.7    Cozzolino, F.8
  • 62
    • 65549134823 scopus 로고    scopus 로고
    • Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-kappaB pathway in human epidermoid carcinoma A431 cells
    • Roy, P.; Kalra, N.; Nigam, N.; George, J.; Ray, R.S.; Hans, R.K.; Prasad, S.; Shukla, Y. Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-kappaB pathway in human epidermoid carcinoma A431 cells. Biochem. Biophys. Res. Commun., 2009, 384(2), 215-220.
    • (2009) Biochem. Biophys. Res. Commun , vol.384 , Issue.2 , pp. 215-220
    • Roy, P.1    Kalra, N.2    Nigam, N.3    George, J.4    Ray, R.S.5    Hans, R.K.6    Prasad, S.7    Shukla, Y.8
  • 63
    • 33745307617 scopus 로고    scopus 로고
    • Ras, PI(3)K and mTOR signalling controls tumour cell growth
    • Shaw, R.J.; Cantley, L.C. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature, 2006, 441(7092), 424-430.
    • (2006) Nature , vol.441 , Issue.7092 , pp. 424-430
    • Shaw, R.J.1    Cantley, L.C.2
  • 64
    • 0036220516 scopus 로고    scopus 로고
    • Involvement of c-jun NH(2)-terminal kinases in resveratrol-induced activation of p53 and apoptosis
    • She, Q.-B.; Huang, C.; Zhang, Y.; Dong, Z. Involvement of c-jun NH(2)-terminal kinases in resveratrol-induced activation of p53 and apoptosis. Mol. Carcinog., 2002, 33(4), 244-250.
    • (2002) Mol. Carcinog , vol.33 , Issue.4 , pp. 244-250
    • She, Q.-B.1    Huang, C.2    Zhang, Y.3    Dong, Z.4
  • 65
    • 3042656673 scopus 로고    scopus 로고
    • Resveratrol suppresses growth of Ishikawa cells through down-regulation of EGF
    • Kaneuchi, M.; Sasaki, M.; Tanaka, Y.; Yamamoto, R.; Sakuragi, N.; Dahiya, R. Resveratrol suppresses growth of Ishikawa cells through down-regulation of EGF. Int. J. Oncol., 2003, 23(4), 1167-1172.
    • (2003) Int. J. Oncol , vol.23 , Issue.4 , pp. 1167-1172
    • Kaneuchi, M.1    Sasaki, M.2    Tanaka, Y.3    Yamamoto, R.4    Sakuragi, N.5    Dahiya, R.6
  • 66
    • 70349736107 scopus 로고    scopus 로고
    • Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: Eukaryotic elongation factor 1A2 as a potential target
    • Lee, M.H.; Choi, B.Y.; Kundu, J.K.; Shin, Y.K.; Na, H.K.; Surh, Y.J. Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target. Cancer Res., 2009, 69(18), 7449-7458.
    • (2009) Cancer Res , vol.69 , Issue.18 , pp. 7449-7458
    • Lee, M.H.1    Choi, B.Y.2    Kundu, J.K.3    Shin, Y.K.4    Na, H.K.5    Surh, Y.J.6
  • 67
    • 1242342067 scopus 로고    scopus 로고
    • Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: Relevance in cell proliferation
    • Pozo-Guisado, E.; Lorenzo-Benayas, M.J.; Fernandez-Salguero, P.M. Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation. Int. J. Cancer, 2004, 109(2), 167-173.
    • (2004) Int. J. Cancer , vol.109 , Issue.2 , pp. 167-173
    • Pozo-Guisado, E.1    Lorenzo-Benayas, M.J.2    Fernandez-Salguero, P.M.3
  • 69
    • 70149104225 scopus 로고    scopus 로고
    • Resveratrol and quercetin cooperate to induce senescence-like growth arrest in C6 rat glioma cells
    • Zamin, L.L.; Filippi-Chiela, E.C.; Dillenburg-Pilla, P.; Horn, F.; Salbego, C.; Lenz, G. Resveratrol and quercetin cooperate to induce senescence-like growth arrest in C6 rat glioma cells. Cancer Sci, 2009, 100(9), 1655-1662.
    • (2009) Cancer Sci , vol.100 , Issue.9 , pp. 1655-1662
    • Zamin, L.L.1    Filippi-Chiela, E.C.2    Dillenburg-Pilla, P.3    Horn, F.4    Salbego, C.5    Lenz, G.6
  • 70
    • 78651428992 scopus 로고    scopus 로고
    • Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling
    • He, X.; Wang, Y.; Zhu, J.; Orloff, M.; Eng, C. Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling. Cancer Lett., 2011, 301(2), 168-176.
    • (2011) Cancer Lett , vol.301 , Issue.2 , pp. 168-176
    • He, X.1    Wang, Y.2    Zhu, J.3    Orloff, M.4    Eng, C.5
  • 72
    • 0034948728 scopus 로고    scopus 로고
    • Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways
    • Yu, R.; Hebbar, V.; Kim, D.W.; Mandlekar, S.; Pezzuto, J.M.; Kong, A.N. Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways. Mol. Pharmacol., 2001, 60(1), 217-224.
    • (2001) Mol. Pharmacol , vol.60 , Issue.1 , pp. 217-224
    • Yu, R.1    Hebbar, V.2    Kim, D.W.3    Mandlekar, S.4    Pezzuto, J.M.5    Kong, A.N.6
  • 73
    • 0032939164 scopus 로고    scopus 로고
    • Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway
    • Huang, C.; Ma, W.Y.; Goranson, A.; Dong, Z. Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway. Carcinogenesis, 1999, 20(2), 237-242.
    • (1999) Carcinogenesis , vol.20 , Issue.2 , pp. 237-242
    • Huang, C.1    Ma, W.Y.2    Goranson, A.3    Dong, Z.4
  • 74
    • 0035866404 scopus 로고    scopus 로고
    • Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase
    • She, Q.B.; Bode, A.M.; Ma, W.Y.; Chen, N.Y.; Dong, Z. Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase. Cancer Res., 2001, 61(4), 1604-1610.
    • (2001) Cancer Res , vol.61 , Issue.4 , pp. 1604-1610
    • She, Q.B.1    Bode, A.M.2    Ma, W.Y.3    Chen, N.Y.4    Dong, Z.5
  • 75
    • 0033515808 scopus 로고    scopus 로고
    • Resveratrolinduced activation of the mitogen-activated protein kinases, ERK1 and ERK2, in human neuroblastoma SH-SY5Y cells
    • Miloso, M.; Bertelli, A.A.; Nicolini, G.; Tredici, G. Resveratrolinduced activation of the mitogen-activated protein kinases, ERK1 and ERK2, in human neuroblastoma SH-SY5Y cells. Neurosci Lett, 1999, 264(1-3), 141-144.
    • (1999) Neurosci Lett , vol.264 , Issue.1-3 , pp. 141-144
    • Miloso, M.1    Bertelli, A.A.2    Nicolini, G.3    Tredici, G.4
  • 76
    • 56349161083 scopus 로고    scopus 로고
    • Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells
    • Madan, E.; Prasad, S.; Roy, P.; George, J.; Shukla, Y. Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells. Biochem. Biophys. Res. Commun., 2008, 377(4), 1232-1237.
    • (2008) Biochem. Biophys. Res. Commun , vol.377 , Issue.4 , pp. 1232-1237
    • Madan, E.1    Prasad, S.2    Roy, P.3    George, J.4    Shukla, Y.5
  • 77
    • 70249113671 scopus 로고    scopus 로고
    • 2,3',4,4',5'Pentamethoxy-trans-stilbene, a resveratrol derivative, is a potent inducer of apoptosis in colon cancer cells via targeting microtubules
    • Li, H.; Wu, W.K.; Zheng, Z.; Che, C.T.; Yu, L.; Li, Z.J.; Wu, Y.C.; Cheng, K.W.; Yu, J.; Cho, C.H.; Wang, M. 2,3',4,4',5'Pentamethoxy-trans-stilbene, a resveratrol derivative, is a potent inducer of apoptosis in colon cancer cells via targeting microtubules. Biochem. Pharmacol., 2009, 78(9), 1224-1232.
    • (2009) Biochem. Pharmacol , vol.78 , Issue.9 , pp. 1224-1232
    • Li, H.1    Wu, W.K.2    Zheng, Z.3    Che, C.T.4    Yu, L.5    Li, Z.J.6    Wu, Y.C.7    Cheng, K.W.8    Yu, J.9    Cho, C.H.10    Wang, M.11
  • 78
    • 62749173154 scopus 로고    scopus 로고
    • Resveratrol analog-3,5,4'-trimethoxy-trans-stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase-2 expression
    • Yang, Y.T.; Weng, C.J.; Ho, C.T.; Yen, G.C. Resveratrol analog-3,5,4'-trimethoxy-trans-stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase-2 expression. Mol Nutr Food Res, 2009, 53(3), 407-416.
    • (2009) Mol Nutr Food Res , vol.53 , Issue.3 , pp. 407-416
    • Yang, Y.T.1    Weng, C.J.2    Ho, C.T.3    Yen, G.C.4
  • 82
    • 84868308799 scopus 로고    scopus 로고
    • Resveratrol, MicroRNAs, Inflammation, and Cancer
    • Tili, E.; Michaille, J.J. Resveratrol, MicroRNAs, Inflammation, and Cancer. J. Nucleic Acids, 2011, 2011, 102-431.
    • (2011) J. Nucleic Acids , vol.2011 , pp. 102-431
    • Tili, E.1    Michaille, J.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.