Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study

Journal of Biomolecular Screening

Volumn 17, Issue 9, 2012, Pages 1136-1150

  Foong, Charlene Shu Fen ^a,b   Sandanaraj, Edwin ^a   Brooks, Harold B ^c   Campbell, Robert M ^c   Ang, Beng Ti ^a,b,d,e   Chong, Yuk Kien ^a,b   Tang, Carol ^d,e,f  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c ELI LILLY AND COMPANY   (United States)

^d NATIONAL NEUROSCIENCE INSTITUTE   (Singapore)

^e DUKE NUS MEDICAL SCHOOL   (Singapore)

^f DIVISION OF MEDICAL ONCOLOGY   (Singapore)

Author keywords

cancer stem cells; glioma; glioma propagating cells; Gravendeel; PLK1; Polo like kinase 1; REMBRANDT; self renewal

Indexed keywords

POLO LIKE KINASE 1; POLO LIKE KINASE 3;

ANIMAL CELL; ARTICLE; BIOINFORMATICS; CELL RENEWAL; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION; GLIOMA CELL; GLIOMA PROPAGATING CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

ANIMALS; BRAIN NEOPLASMS; CELL CYCLE PROTEINS; CELL PROLIFERATION; CELL SURVIVAL; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; DISEASE PROGRESSION; DRUG SCREENING ASSAYS, ANTITUMOR; GLIOMA; HUMANS; INHIBITORY CONCENTRATION 50; MICE; MICROARRAY ANALYSIS; NEOPLASTIC STEM CELLS; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PTERIDINES; SMALL MOLECULE LIBRARIES; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED;

EID: 84866411726     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112457820     Document Type: Article

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