Pathological roles of purinergic signaling in the liver

Journal of Hepatology

Volumn 57, Issue 4, 2012, Pages 916-920

  Vaughn, Byron P ^a   Robson, Simon C ^a   Burnstock, Geoffrey ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

CD39; CD73; Ectonucleotidases; Liver disease; P2 receptor; T lymphocytes

Indexed keywords

ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; CD39 ANTIGEN; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y2 RECEPTOR;

ALCOHOL LIVER DISEASE; ANGIOGENESIS; ARTICLE; CARCINOGENESIS; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; DISEASE COURSE; ENZYME ACTIVITY; FATTY LIVER; GLUCOSE METABOLISM; HEPATIC ENCEPHALOPATHY; HEPATITIS C VIRUS; HEPATORENAL SYNDROME; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; LIPOLYSIS; LIVER CANCER; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER FUNCTION; LIVER INJURY; LIVER REGENERATION; LIVER TRANSPLANTATION; MORTALITY; NATURAL KILLER CELL; PATHOPHYSIOLOGY; PORTAL HYPERTENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURINE METABOLISM; SIGNAL TRANSDUCTION; URINE VOLUME;

EID: 84866409390     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.06.008     Document Type: Note

References (27)

1. V. Ralevic, and G. Burnstock Receptors for purines and pyrimidines Pharmacol Rev 1998 412 492
2. S.C. Robson, Y. Wu, X. Sun, C. Knosalla, K. Dwyer, and K. Enjyoji Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation Semin Thromb Hemost 2005 217 233
3. G. Beldi, Y. Wu, X. Sun, M. Imai, K. Enjyoji, and E. Csizmadia Regulated catalysis of extracellular nucleotides by vascular CD39/ENTPD1 is required for liver regeneration Gastroenterology 135 2008 1751 1760
4. 2 following trauma-hemorrhage and resuscitation: downregulation of inflammatory cytokine (TNF, IL-6) release J Surg Res 52 1992 364 371
5. X. Sun, M. Imai, M. Nowak-Machen, O. Guckelberger, K. Enjyoji, and Y. Wu Liver damage and systemic inflammatory responses are exacerbated by the genetic deletion of CD39 in total hepatic ischemia Purinergic Signalling 7 2011 427 434
6. G. Beldi, Y. Banz, A. Kroemer, X. Sun, Y. Wu, and N. Graubardt Deletion of CD39 on natural killer cells attenuates hepatic ischemia/reperfusion injury in mice Hepatology 51 2010 1702 1711
7. M.L. Hart, I.C. Gorzolla, J. Schittenhelm, S.C. Robson, and H.K. Eltzschig SP1-dependent induction of CD39 facilitates hepatic ischemic preconditioning J Immunol 184 2010 4017 4024
8. S. Crumm, M. Cofan, E. Juskeviciute, and J.B. Hoek Adenine nucleotide changes in the remnant liver: an early signal for regeneration after partial hepatectomy Hepatology 48 2008 898 908
9. S. Thevananther, H. Sun, A. Hernandez, S.S. Awad, and S.J. Karpen Impaired hepatocellular proliferation in P2Y2 purinergic receptor knockout mice: mitogenic role of extracellular ATP Hepatology 44 2008 206A
10. G. Beldi, K. Enjyoji, Y. Wu, L. Miller, Y. Banz, and X. Sun The role of purinergic signaling in the liver and in transplantation: effects of extracellular nucleotides on hepatic graft vascular injury, rejection and metabolism Front Biosci 13 2008 2588 2603
11. I. Cadden, N. Partovi, and E.M. Yoshida Review article: possible beneficial effects of coffee on liver disease and function Aliment Pharmacol Ther 26 2007 1 8
12. R. Hernández-Muñoz, M. Díaz-Muñoz, J.A. Suárez-Cuenca, C. Trejo-Solís, V. López, and L. Sánchez-Sevilla Adenosine reverses a preestablished CCl4-induced micronodular cirrhosis through enhancing collagenolytic activity and stimulating hepatocyte cell proliferation in rats Hepatology 34 2001 677 687
13. J.A. Dranoff, M. Ogawa, E.A. Kruglov, M.D.A. Gaça, J. Sévigny, and S.C. Robson Expression of P2Y nucleotide receptors and ectonucleotidases in quiescent and activated rat hepatic stellate cells Am J Physiol Gastrointest Liver Physiol 287 2004 G417 G424
14. J.A. Dranoff, E.A. Kruglov, J. Toure, N. Braun, H. Zimmermann, and D. Jain Ectonucleotidase NTPDase2 is selectively down-regulated in biliary cirrhosis J Investig Med 52 2004 475 482
15. A. Zipprich, W.Z. Mehal, C. Ripoll, and R.J. Groszmann A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatory response in the CCL-cirrhotic liver Liver Int 30 2010 988 994
16. Z. Ming, and W.W. Lautt Caffeine-induced natriuresis and diuresis via blockade of hepatic adenosine-mediated sensory nerves and a hepatorenal reflex Can J Physiol Pharmacol 88 2010 1115 1121
17. B. Hocher, S. Heiden, K. von Websky, A.M. Arafat, J. Rahnenfuhrer, and M. Alter Renal effects of the novel selective adenosine A1 receptor blocker SLV329 in experimental liver cirrhosis in rats PLoS One 6 2011 e17891
18. W. Schmidt, G. Wolf, K. Grüngreiff, and K. Linke Adenosine influences the high-affinity uptake of transmitter glutamate and aspartate under conditions of hepatic encephalopathy Metab Brain Dis 8 1993 73 80
19. X. Sun, Y. Wu, W. Gao, K. Enjyoji, E. Csizmadia, and C.E. Müller CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice Gastroenterology 139 2010 1030 1040
20. L. Feng, X. Sun, E. Csizmadia, L. Han, S. Bian, and T. Murakami Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate Neoplasia 13 2011 206 216
21. M. Fang, Z. Shen, S. Huang, L. Zhao, S. Chen, and T.W. Mak The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway Cell 143 2010 711 724
22. K. Enjyoji, K. Kotani, C. Thukral, B. Blumel, X. Sun, and Y. Wu Deletion of Cd39/Entpd1 results in hepatic insulin resistance Diabetes 57 2008 2311 2320
23. Z. Peng, P.A. Borea, T. Wilder, H. Yee, L. Chiriboga, and M.R. Blackburn Adenosine signaling contributes to ethanol-induced fatty liver in mice J Clin Investig 119 2009 582 594
24. R. Hoque, M.A. Sohail, S. Salhanick, A.F. Malik, A. Ghani, and S.C. Robson P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice Am J Physiol Gastrointest Liver Physiol 302 2012 G1171 G1179
25. Y. Sudo, S. Takaya, M. Kobayashi, A. Fukuda, O. Harada, and T. Suto Assessment of graft viability using hyaluronic acid and adenosine triphosphate in orthotopic liver transplantation from non-heart-beating donors Transplant Proc 32 2000 2114 2115
26. 2 on acute hepatic ischemia Transplant Proc 19 1987 1324 1326
27. S. Mizuno, T. Hamada, K. Nakatani, M. Kishiwada, M. Usul, and H. Sakurai Monitoring peripheral blood CD4+ adenosine triphosphate activity after living donor liver transplantation: impact of combination assays of immune function and CYP3A5 genotype J Hepatobiliary Pancreat Sci 18 2011 226 232