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Volumn 60, Issue 36, 2012, Pages 9120-9129

Anti-inflammatory activities of an ethanol extract of Ecklonia stolonifera in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells

Author keywords

anti inflammation; Ecklonia stolonifera; MAP kinases; NF B; RAW 264.7 cells

Indexed keywords

ANTI-INFLAMMATION; ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY ACTION; ANTI-INFLAMMATORY ACTIVITY; BROWN ALGAE; CHEMOPREVENTIVE ACTIVITY; CYCLOOXYGENASE 2; CYTOKINES; DOSE-DEPENDENT MANNER; ECKLONIA STOLONIFERA; ETHANOL EXTRACT; ETHANOLIC EXTRACTS; INDUCIBLE NITRIC OXIDE SYNTHASE; INFLAMMATORY DISEASE; LIPOPOLYSACCHARIDES; MAP KINASE; MOLECULAR MECHANISM; MURINE MACROPHAGES; NUCLEAR FACTORS; P38 MAPK; POTENTIAL SOURCES; PROSTAGLANDINE; THERAPEUTIC AGENTS; TRANSCRIPTIONAL ACTIVITY;

EID: 84866407367     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf3022018     Document Type: Conference Paper
Times cited : (65)

References (36)
  • 1
    • 0027255749 scopus 로고
    • Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial lipopolysaccharide
    • Xie, Q. W.; Whisnant, R.; Nathan, C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial lipopolysaccharide J. Exp. Med. 1993, 177, 1779-1784
    • (1993) J. Exp. Med. , vol.177 , pp. 1779-1784
    • Xie, Q.W.1    Whisnant, R.2    Nathan, C.3
  • 3
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan, C. Nitric oxide as a secretory product of mammalian cells FASEB J. 1992, 6, 3051-3064
    • (1992) FASEB J. , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 5
    • 38749112555 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: From vascular biology to biomarker discovery and risk prediction
    • Packard, R. R.; Libby, P. Inflammation in atherosclerosis: From vascular biology to biomarker discovery and risk prediction Clin. Chem. 2008, 54, 24-38
    • (2008) Clin. Chem. , vol.54 , pp. 24-38
    • Packard, R.R.1    Libby, P.2
  • 6
    • 0029941097 scopus 로고    scopus 로고
    • Transcriptional regulation of the human iNOS gene in vascular-smooth- muscle cells and macrophages: Evidence for tissue specificity
    • Kolyada, A. Y.; Savikovsky, N.; Madias, N. E. Transcriptional regulation of the human iNOS gene in vascular-smooth-muscle cells and macrophages: evidence for tissue specificity Biochem. Biophys. Res. Commun. 1996, 220, 600-605
    • (1996) Biochem. Biophys. Res. Commun. , vol.220 , pp. 600-605
    • Kolyada, A.Y.1    Savikovsky, N.2    Madias, N.E.3
  • 7
    • 0030608878 scopus 로고    scopus 로고
    • Involvement of NF-κB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages
    • D'Acquisto, F.; Iuvone, T.; Rombola, L.; Sautebin, L.; Di Rosa, M.; Carnuccio, R. Involvement of NF-κB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages FEBS Lett. 1997, 418, 175-178
    • (1997) FEBS Lett. , vol.418 , pp. 175-178
    • D'Acquisto, F.1    Iuvone, T.2    Rombola, L.3    Sautebin, L.4    Di Rosa, M.5    Carnuccio, R.6
  • 8
    • 0032575626 scopus 로고    scopus 로고
    • Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor κb-binding sites
    • Marks-Konczalik, J.; Chu, S. C.; Moss, J. Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor κB-binding sites J. Biol. Chem. 1998, 273, 22201-22208
    • (1998) J. Biol. Chem. , vol.273 , pp. 22201-22208
    • Marks-Konczalik, J.1    Chu, S.C.2    Moss, J.3
  • 9
    • 0034942860 scopus 로고    scopus 로고
    • NF-κB in rheumatoid arthritis: A pivotal regulator of inflammation, hyperplasia, and tissue destruction
    • Makarov, S. S. NF-κB in rheumatoid arthritis: A pivotal regulator of inflammation, hyperplasia, and tissue destruction Arthritis Res. 2001, 3, 200-2006
    • (2001) Arthritis Res. , vol.3 , pp. 200-2006
    • Makarov, S.S.1
  • 10
    • 0029146930 scopus 로고
    • Signal-induced site-specific phosphorylation targets IκB-α to the ubiquitin-proteasome pathway
    • Chen, Z.; Hagler, J.; Palombella, V. J.; Melandri, F.; Scherer, D.; Ballard, D.; Maniatis, T. Signal-induced site-specific phosphorylation targets IκB-α to the ubiquitin-proteasome pathway Genes Dev. 1995, 9, 1586-1597
    • (1995) Genes Dev. , vol.9 , pp. 1586-1597
    • Chen, Z.1    Hagler, J.2    Palombella, V.J.3    Melandri, F.4    Scherer, D.5    Ballard, D.6    Maniatis, T.7
  • 11
    • 0032032424 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-α gene expression in endotoxin-stimulated primary glial cultures
    • Bhat, N. R.; Zhang, P.; Lee, J. C.; Hogan, E. L. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-α gene expression in endotoxin-stimulated primary glial cultures J. Neurosci. 1998, 18, 1633-1641
    • (1998) J. Neurosci. , vol.18 , pp. 1633-1641
    • Bhat, N.R.1    Zhang, P.2    Lee, J.C.3    Hogan, E.L.4
  • 12
    • 44449154463 scopus 로고    scopus 로고
    • 2 terminal kinase (JNK) is an essential mediator of Toll-like receptor 2-induced corneal inflammation
    • 2 terminal kinase (JNK) is an essential mediator of Toll-like receptor 2-induced corneal inflammation J. Leukocyte Biol. 2008, 83, 991-997
    • (2008) J. Leukocyte Biol. , vol.83 , pp. 991-997
    • Adhikary, G.1    Sun, Y.2    Pearlman, E.3
  • 13
    • 79960516624 scopus 로고    scopus 로고
    • Akt-Mediated proinflammatory response of mononuclear phagocytes infected with Burkholderia cenocepacia occurs by a novel GSK3β-dependent, IκB kinase-independent mechanism
    • Cremer, T. J.; Shah, P.; Cormet-Boyaka, E.; Valvano, M. A.; Butchar, J. P.; Tridandapani, S. Akt-Mediated proinflammatory response of mononuclear phagocytes infected with Burkholderia cenocepacia occurs by a novel GSK3β-dependent, IκB kinase-independent mechanism J. Immunol. 2011, 187, 635-643
    • (2011) J. Immunol. , vol.187 , pp. 635-643
    • Cremer, T.J.1    Shah, P.2    Cormet-Boyaka, E.3    Valvano, M.A.4    Butchar, J.P.5    Tridandapani, S.6
  • 14
    • 19344363575 scopus 로고    scopus 로고
    • Activation of phosphoinositide 3-kinase in response to inflammation and nitric oxide leads to the up-regulation of cyclooxygenase-2 expression and subsequent cell proliferation in mesangial cells
    • Sheu, M. L.; Chao, K. F.; Sung, Y. J.; Lin, W. W.; Lin-Shiau, S. Y.; Liu, S. H. Activation of phosphoinositide 3-kinase in response to inflammation and nitric oxide leads to the up-regulation of cyclooxygenase-2 expression and subsequent cell proliferation in mesangial cells Cell. Signal. 2005, 17, 975-984
    • (2005) Cell. Signal. , vol.17 , pp. 975-984
    • Sheu, M.L.1    Chao, K.F.2    Sung, Y.J.3    Lin, W.W.4    Lin-Shiau, S.Y.5    Liu, S.H.6
  • 15
    • 0242564783 scopus 로고
    • Chinese seaweeds in herbal medicine
    • Tseng, C. K. Chinese seaweeds in herbal medicine Hydrobiologia 1984, 116/117, 152-154
    • (1984) Hydrobiologia , vol.116-117 , pp. 152-154
    • Tseng, C.K.1
  • 17
    • 4644304417 scopus 로고    scopus 로고
    • Inhibitory phlorotannins from the edible brown alga Ecklonia stolonifera on total reactive oxygen species (ROS) generation
    • Kang, H. S.; Chung, H. Y.; Kim, J. Y.; Son, B. W.; Jung, H. A.; Choi, J. S. Inhibitory phlorotannins from the edible brown alga Ecklonia stolonifera on total reactive oxygen species (ROS) generation Arch. Pharm. Res. 2004, 27, 194-198
    • (2004) Arch. Pharm. Res. , vol.27 , pp. 194-198
    • Kang, H.S.1    Chung, H.Y.2    Kim, J.Y.3    Son, B.W.4    Jung, H.A.5    Choi, J.S.6
  • 18
    • 80051962940 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase 1B and α-glucosidase inhibitory phlorotannins from edible brown algae, Ecklonia stolonifera and Eisenia bicyclis
    • Moon, H. E.; Islam, N.; Ahn, B. R.; Chowdhury, S. S.; Sohn, H. S.; Jung, H. A.; Choi, J. S. Protein tyrosine phosphatase 1B and α-glucosidase inhibitory phlorotannins from edible brown algae, Ecklonia stolonifera and Eisenia bicyclis Biosci., Biotechnol., Biochem. 2011, 75, 1472-1480
    • (2011) Biosci., Biotechnol., Biochem. , vol.75 , pp. 1472-1480
    • Moon, H.E.1    Islam, N.2    Ahn, B.R.3    Chowdhury, S.S.4    Sohn, H.S.5    Jung, H.A.6    Choi, J.S.7
  • 19
    • 58449103316 scopus 로고    scopus 로고
    • Anti-hyperlipidemic effect of an edible brown algae, Ecklonia stolonifera, and its constituents on poloxamer 407-induced hyperlipidemic and cholesterol-fed rats
    • Yoon, N. Y.; Kim, H. R.; Chung, H. Y.; Choi, J. S. Anti-hyperlipidemic effect of an edible brown algae, Ecklonia stolonifera, and its constituents on poloxamer 407-induced hyperlipidemic and cholesterol-fed rats Arch. Pharm. Res. 2008, 31, 1564-1571
    • (2008) Arch. Pharm. Res. , vol.31 , pp. 1564-1571
    • Yoon, N.Y.1    Kim, H.R.2    Chung, H.Y.3    Choi, J.S.4
  • 20
    • 33746773084 scopus 로고    scopus 로고
    • The inhibitory effects of eckol and dieckol from Ecklonia stolonifera on the expression of matrix metalloproteinase-1 in human dermal fibroblasts
    • Joe, M. J.; Kim, S. N.; Choi, H. Y.; Shin, W. S.; Park, G. M.; Kang, D. W.; Kim, Y. K. The inhibitory effects of eckol and dieckol from Ecklonia stolonifera on the expression of matrix metalloproteinase-1 in human dermal fibroblasts Biol. Pharm. Bull. 2006, 29, 1735-1739
    • (2006) Biol. Pharm. Bull. , vol.29 , pp. 1735-1739
    • Joe, M.J.1    Kim, S.N.2    Choi, H.Y.3    Shin, W.S.4    Park, G.M.5    Kang, D.W.6    Kim, Y.K.7
  • 21
    • 84861627243 scopus 로고    scopus 로고
    • Isolation and Identification of phlorotannins from Ecklonia stolonifera with antioxidant and hepatoprotective properties in tacrine-treated HepG2 cells
    • Lee, M. S.; Shin, T. S.; Utsuki, T.; Choi, J. S.; Byun, D. S.; Kim, H. R. Isolation and Identification of phlorotannins from Ecklonia stolonifera with antioxidant and hepatoprotective properties in tacrine-treated HepG2 cells J. Agric. Food Chem. 2012, 60, 5340-5349
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 5340-5349
    • Lee, M.S.1    Shin, T.S.2    Utsuki, T.3    Choi, J.S.4    Byun, D.S.5    Kim, H.R.6
  • 22
    • 65649088598 scopus 로고    scopus 로고
    • Anti-inflammatory effect of Ishige okamurae ethanolic extract via inhibition of NF-κB transcription factor in RAW 264.7 cells
    • Kim, M. M.; Rajapakse, N.; Kim, S. K. Anti-inflammatory effect of Ishige okamurae ethanolic extract via inhibition of NF-κB transcription factor in RAW 264.7 cells Phytother. Res. 2009, 23, 628-634
    • (2009) Phytother. Res. , vol.23 , pp. 628-634
    • Kim, M.M.1    Rajapakse, N.2    Kim, S.K.3
  • 23
    • 58149518005 scopus 로고    scopus 로고
    • Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-κB pathways
    • Jung, W. K.; Ahn, Y. W.; Lee, S. H.; Choi, Y. H.; Kim, S. K.; Yea, S. S.; Choi, I.; Park, S. G.; Seo, S. K.; Lee, S. W.; Choi, I. W. Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-κB pathways Food Chem. Toxicol. 2009, 47, 410-417
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 410-417
    • Jung, W.K.1    Ahn, Y.W.2    Lee, S.H.3    Choi, Y.H.4    Kim, S.K.5    Yea, S.S.6    Choi, I.7    Park, S.G.8    Seo, S.K.9    Lee, S.W.10    Choi, I.W.11
  • 24
    • 0035104119 scopus 로고    scopus 로고
    • LPS induction of gene expression in human monocytes
    • Guha, M.; Mackman, N. LPS induction of gene expression in human monocytes Cell. Signal. 2001, 13, 85-94
    • (2001) Cell. Signal. , vol.13 , pp. 85-94
    • Guha, M.1    MacKman, N.2
  • 25
    • 77249174822 scopus 로고    scopus 로고
    • Anti-inflammatory activity of new compounds from Andrographis paniculata by NF-κB transactivation inhibition
    • Chao, W. W.; Kuo, Y. H.; Lin, B. F. Anti-inflammatory activity of new compounds from Andrographis paniculata by NF-κB transactivation inhibition J. Agric. Food Chem. 2010, 58, 2505-2512
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 2505-2512
    • Chao, W.W.1    Kuo, Y.H.2    Lin, B.F.3
  • 26
    • 79952155693 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide (LPS)-induced inflammatory responses by Sargassum hemiphyllum sulfated polysaccharide extract in RAW 264.7 macrophage cells
    • Hwang, P. A.; Chien, S. Y.; Chan, Y. L.; Lu, M. K.; Wu, C. H.; Kong, Z. L.; Wu, C. J. Inhibition of lipopolysaccharide (LPS)-induced inflammatory responses by Sargassum hemiphyllum sulfated polysaccharide extract in RAW 264.7 macrophage cells J. Agric. Food Chem. 2011, 59, 2062-2068
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 2062-2068
    • Hwang, P.A.1    Chien, S.Y.2    Chan, Y.L.3    Lu, M.K.4    Wu, C.H.5    Kong, Z.L.6    Wu, C.J.7
  • 27
    • 80053097456 scopus 로고    scopus 로고
    • Protective effect of Monascus -fermented red mold rice against alcoholic liver disease by attenuating oxidative stress and inflammatory response
    • Cheng, C. F.; Pan, T. M. Protective effect of Monascus -fermented red mold rice against alcoholic liver disease by attenuating oxidative stress and inflammatory response J. Agric. Food Chem. 2011, 59, 9950-9957
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 9950-9957
    • Cheng, C.F.1    Pan, T.M.2
  • 29
    • 66149110657 scopus 로고    scopus 로고
    • Inhibitory effects and molecular mechanism of dieckol isolated from marine brown alga on COX-2 and iNOS in microglial cells
    • Jung, W. K.; Heo, S. J.; Jeon, Y. J.; Lee, C. M.; Park, Y. M.; Byun, H. G.; Choi, Y. H.; Park, S. G.; Choi, I. W. Inhibitory effects and molecular mechanism of dieckol isolated from marine brown alga on COX-2 and iNOS in microglial cells J. Agric. Food Chem. 2009, 57, 4439-4446
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 4439-4446
    • Jung, W.K.1    Heo, S.J.2    Jeon, Y.J.3    Lee, C.M.4    Park, Y.M.5    Byun, H.G.6    Choi, Y.H.7    Park, S.G.8    Choi, I.W.9
  • 30
    • 82655173811 scopus 로고    scopus 로고
    • Phlorofucofuroeckol A inhibits the LPS-stimulated iNOS and COX-2 expressions in macrophages via inhibition of NF-κB, Akt, and p38 MAP
    • Kim, A. R.; Lee, M. S.; Shin, T. S.; Hua, H.; Jang, B. C.; Choi, J. S.; Byun, D. S.; Utsuki, T.; Ingram, D.; Kim, H. R. Phlorofucofuroeckol A inhibits the LPS-stimulated iNOS and COX-2 expressions in macrophages via inhibition of NF-κB, Akt, and p38 MAP Toxicol In Vitro 2011, 25, 1789-1795
    • (2011) Toxicol in Vitro , vol.25 , pp. 1789-1795
    • Kim, A.R.1    Lee, M.S.2    Shin, T.S.3    Hua, H.4    Jang, B.C.5    Choi, J.S.6    Byun, D.S.7    Utsuki, T.8    Ingram, D.9    Kim, H.R.10
  • 31
    • 0035379555 scopus 로고    scopus 로고
    • Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38
    • Madrid, L. V.; Mayo, M. W.; Reuther, J. Y.; Baldwin, A. S., Jr. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38 J. Biol. Chem. 2001, 276, 18934-18940
    • (2001) J. Biol. Chem. , vol.276 , pp. 18934-18940
    • Madrid, L.V.1    Mayo, M.W.2    Reuther, J.Y.3    Baldwin Jr., A.S.4
  • 32
    • 0036781052 scopus 로고    scopus 로고
    • NF-κB regulation in the immune system
    • Li, Q.; Verma, I. M. NF-κB regulation in the immune system Nat. Rev. Immunol. 2002, 2, 725-734
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 33
    • 21244485124 scopus 로고    scopus 로고
    • Lipoteichoic acid induces nuclear factor-κB activation and nitric oxide synthase expression via phosphatidylinositol 3-kinase, Akt, and p38 MAPK in RAW 264.7 macrophages
    • Kao, S. J.; Lei, H. C.; Kuo, C. T.; Chang, M. S.; Chen, B. C.; Chang, Y. C.; Chiu, W. T.; Lin, C. H. Lipoteichoic acid induces nuclear factor-κB activation and nitric oxide synthase expression via phosphatidylinositol 3-kinase, Akt, and p38 MAPK in RAW 264.7 macrophages Immunology 2005, 115, 366-374
    • (2005) Immunology , vol.115 , pp. 366-374
    • Kao, S.J.1    Lei, H.C.2    Kuo, C.T.3    Chang, M.S.4    Chen, B.C.5    Chang, Y.C.6    Chiu, W.T.7    Lin, C.H.8
  • 35
    • 64649096209 scopus 로고    scopus 로고
    • Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds
    • Wang, T.; Jonsdottir, R.; Olafsdottir, G. Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds Food Chem. 2009, 116, 240-248
    • (2009) Food Chem. , vol.116 , pp. 240-248
    • Wang, T.1    Jonsdottir, R.2    Olafsdottir, G.3
  • 36
    • 33750532308 scopus 로고    scopus 로고
    • Regulation of inflammation and redox signaling by dietary polyphenols
    • Rahman, I.; Biswas, S. K.; Kirkham, P. A. Regulation of inflammation and redox signaling by dietary polyphenols Biochem. Pharmacol. 2006, 72, 1439-1452
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1439-1452
    • Rahman, I.1    Biswas, S.K.2    Kirkham, P.A.3


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