An improved model to predict physiologically based model parameters and their inter-individual variability from anthropometry

Critical Reviews in Toxicology

Volumn 42, Issue 9, 2012, Pages 751-767

  Bosgra, Sieto ^a,b   Van Eijkeren, Jan ^b   Bos, Peter ^b   Zeilmaker, Marco ^b   Slob, Wout ^a,b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

Age; Allometric scaling; Body weight; Generic PBPK model; Height; Human physiology; Inter individual variability; Obesity

Indexed keywords

ADOLESCENT; ADULT; AGE; AGED; ANTHROPOMETRY; BLOOD FLOW; BODY HEIGHT; BODY SURFACE; BODY WEIGHT; BREATHING RATE; CHILD; FEMALE; FUNCTIONAL RESIDUAL CAPACITY; GENDER; HEART OUTPUT; HUMAN; INFANT; INTERMETHOD COMPARISON; LUNG VENTILATION; LUNG VOLUME; MALE; NEWBORN; ORGAN WEIGHT; PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL; PHYSIOLOGY; POPULATION MODEL; PRESCHOOL CHILD; QUANTITATIVE ANALYSIS; REVIEW; SCHOOL CHILD; STATISTICAL MODEL; TIDAL VOLUME;

ADIPOSE TISSUE; ANTHROPOMETRY; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; HUMANS; MODELS, BIOLOGICAL; ORGAN SIZE; RISK ASSESSMENT;

EID: 84866405543     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.3109/10408444.2012.709225     Document Type: Review

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