Vitamin E protects against lipid peroxidation and rescues tumorigenic phenotypes in cowden/cowden-like patient-derived lymphoblast cells with germline SDHx variants

Clinical Cancer Research

Volumn 18, Issue 18, 2012, Pages 4954-4961

  Ni, Ying ^a,c   Eng, Charis ^a,b,c,d,e  

^a LERNER RESEARCH INSTITUTE   (United States)

^b Taussig Cancer Institute   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SUCCINATE DEHYDROGENASE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL PROTECTION; CONTROLLED STUDY; COWDEN SYNDROME; DRUG MECHANISM; GENE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GERM LINE; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LYMPHOBLAST; MITOCHONDRION; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SDHX GENE;

ALPHA-TOCOPHEROL; ANTIOXIDANTS; APOPTOSIS; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; GERM-LINE MUTATION; HAMARTOMA SYNDROME, MULTIPLE; HUMANS; LIPID PEROXIDATION; MITOCHONDRIA; OXIDATION-REDUCTION; PHENOTYPE; POLYMORPHISM, GENETIC; SUCCINATE DEHYDROGENASE; TUMOR SUPPRESSOR PROTEIN P53; VITAMIN E;

EID: 84866386315     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-12-1055     Document Type: Article

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