Matching biochemical and functional efficacies confirm ZIP as a potent competitive inhibitor of PKMζ in neurons

Neuropharmacology

Volumn 64, Issue , 2013, Pages 37-44

  Yao, Yudong ^a   Shao, Charles ^a   Jothianandan, Desingarao ^a   Tcherepanov, Andrew ^a   Shouval, Harel ^b   Sacktor, Todd Charlton ^a,c  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c Downstate Health Sciences University   (United States)

Author keywords

aPKC; Chelerythrine; PKM ; Staurosporine; ZIP

Indexed keywords

AMPA RECEPTOR; CHELERYTHRINE; HYBRID PROTEIN; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE C ZETA; PROTEIN KINASE M ZETA; STAUROSPORINE; UNCLASSIFIED DRUG; ZETA INHIBITORY PEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN SLICE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; HIPPOCAMPUS; IN VITRO STUDY; MALE; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BENZOPHENANTHRIDINES; BINDING, COMPETITIVE; CELL LINE; CELLS, CULTURED; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; NERVE TISSUE PROTEINS; NEURONS; OLIGOPEPTIDES; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; SYNAPTIC TRANSMISSION;

EID: 84866376318     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.07.018     Document Type: Article

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